Clinical trials: Cardiovascular Event
Cardiovascular Diseases, Heart Diseases
Epidemiology of Insulin Growth Factor (IGF) and Cardiovascular Events
To explore the role of insulin growth factor in cardiovascular disease in older men and women.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00086424
- Volunteers
- 5,888 people
- Sponsor
- Albert Einstein College of Medicine
Heart Failure, Heart Failure With Reduced Ejection Fraction
Demographic, Clinical, Biological, Treatment Characteristics and Cardiovascular Events of Patients With Heart Failure in Vietnam: a Multicenter Prospective Observational Study
Describe the clinical characteristics, paraclinical features, and treatment during hospitalization, as well as at 1, 3, and 12 months post-discharge, of heart failure patients at selected cardiovascular centers in Vietnam.
- Conditions
- Heart Failure, Heart Failure With Reduced Ejection Fraction, Heart Failure With Mid Range Ejection Fraction
- Trial name
- MCR-HF (NCT06516562)
- Testing
- Optimal treatment
- Where
- Vietnam
- Volunteers
- 2,500 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Acute Coronary Syndrome, Tobacco Use
Post Acute Cardiac Event Smoking (PACES) Study
Summary of the Project : Quitting smoking following acute coronary syndrome (ACS) can reduce mortality up to 50%. However, depression and smoking are highly co-morbid and depressed mood may interfere with cessation and…
- Trial name
- NCT03413423
- Testing
- BAT-CS, Smoking Cessation and Health & Wellness
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- Hennepin Healthcare Research Institute
Ventricular Dysfunction, Left, Major Adverse Cardiac Events
Echo-guided Hemodynamic Management Strategy in Elderly Patients Undergoing Noncardiac Surgery
Elderly patients are the fastest growing surgical population and have an increased risk of postoperative cardiac problems. Diastolic dysfunction, or the reduced ability of the heart' s ventricles to fill completely, is common in…
- Trial name
- NCT01780727
- Testing
- EGHEM
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- University of Nebraska
Cardiac Arrest
One Year Follow-up After Rescuscited Cardiac Arrest
While 80 % of all sudden cardiac death (SCD) result from coronary artery disease (CHD) approximatively 2/3 of SCD occur as a first manifestation of the CHD.
- Trial name
- ONYRCA (NCT04796727)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Relapsed/Refractory Multiple Myeloma
A Study to Assess Adverse Events and Change in Disease State of Intravenously (IV) Infused Etentamig (ABBV-383) of Adult Participants With Relapsed or Refractory Multiple Myeloma in Japan
Multiple myeloma (MM) is an incurable disease characterized by the growth of monoclonal plasma cells in the bone marrow. The purpose of this study is to assess the adverse events and change in disease state of etentamig in adult…
- Trial name
- NCT05286229
- Testing
- Etentamig
- Where
- 6 sites in Japan
- Volunteers
- 8 people
- Sponsor
- AbbVie
Cardiac Event, Emotions
Emotion Regulation Intervention to Sustain Physical Activity in Rural-dwelling Women and Men After Myocardial Infarction
The purpose of this study is to evaluate early preliminary efficacy of the eMotion intervention in US adults who have experienced a first cardiac event and participating in phase II cardiac rehabilitation.
- Trial name
- eMotion (NCT04441086)
- Testing
- eMotion, Healthy Living Active Control
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Indiana University
Functional Disability, Dementia
Aspirin in Reducing Events in the Elderly
ASPREE-XT is a post-treatment, longitudinal observational follow-up study of ASPREE participants [ASPREE Investigator Group, 2013; www.aspree.org; McNeil et al 2017].
- Conditions
- Functional Disability, Dementia, Heart Disease, Stroke
- Trial name
- ASPREE (NCT01038583)
- Testing
- 100 mg enteric-coated aspirin
- Where
- 47 sites in United States, Australia
- Volunteers
- 19,114 people, healthy volunteers welcome
- Sponsor
- Hennepin Healthcare Research Institute
Peripheral Arterial Disease
Prevention of Ischemic Events in Patients With Peripheral Arterial Disease
The PID-PAB study aims to test the efficacy of the European Guidelines on Cardiovascular Disease Prevention in patients with peripheral arterial disease.
- Trial name
- PID-PAB (NCT00761969)
- Testing
- Implementation of the European Guidelines on cardiovascular Disease Prevention in Clinical Practice
- Where
- Slovenia
- Volunteers
- 1,455 people, healthy volunteers welcome
- Sponsor
- KRKA
Hypertension
Ambulatory Blood Pressure Monitoring in the Prediction of Cardiovascular Events and Effects of Chronotherapy
The MAPEC study was designed to investigate whether normalizing the circadian blood pressure profile towards a more dipper pattern (increasing the diurnal/nocturnal ratio of blood pressure) by the use of Chronotherapy (that is…
- Trial name
- MAPEC (NCT00295542)
- Testing
- Ambulatory blood pressure monitoring, Chronotherapy, timing of antihypertensive medication, ACEI (including spirapril, enalapril, quinapril, lisinopril)
- Where
- Spain
- Volunteers
- 3,344 people, healthy volunteers welcome
- Sponsor
- University of Vigo
Mortality of Patients with CVD, Mortality of Patients with CVD and T2DM
The Impact of Type 2 Diabetes Mellitus on Cardiovascular Events in Saudi Arabia Now and Future
Cardiovascular disease (CVD) and Type 2 diabetes mellitus (T2DM) are major global health challenges with significant morbidity and mortality. In Saudi Arabia, the prevalence of CVD and T2DM is increasing.
- Conditions
- Mortality of Patients with CVD, Mortality of Patients with CVD and T2DM, Mortality of Patients with T2DM, Mortality of Patients with Neither
- Trial name
- NCT06674161
- Volunteers
- 80 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Down Syndrome, Bradycardia
Down Syndrome Autonomic Nervous System Induction Bradycardia
Children with Down syndrome (DS) often experience dangerously low heart rates on induction of anesthesia for routine procedures and this occurs at 10 times the rate of non-DS patients.
- Trial name
- DANSIB (NCT05120531)
- Testing
- Monitoring patients undergoing surgery to look for association between ANS activity and bradycardia
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Coronary Artery Disease
Correlation of Biomarkers With the Presence and Severity of Coronary Artery Disease
The development of coronary artery disease is multifactorial. Peripheral blood biomarkers paly an important role in the prediction of coronary artery disease.
- Trial name
- PREDICTION-NJ (NCT05015270)
- Testing
- Medications or percutaneous coronary intervention
- Where
- China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Red Blood Cell Distribution Width-to-albumin Ratio, Acute Myocardial Infarction (AMI)
Relationship Between RAR and MACEs in AMI-CS Patients During Hospitalization
This is a retrospective study from double center: Xuzhou Central Hospital and The First People's Hospital of Yancheng. Acute myocardial infarction (AMI) were screened and AMI complicating with cardiogenic shock were included.
- Conditions
- Red Blood Cell Distribution Width-to-albumin Ratio, Acute Myocardial Infarction (AMI), Major Adverse Cardiovascular Events
- Trial name
- NCT07507110
- Testing
- Includ the inclusion/exclusion criteria of AMI-CS
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Xuzhou Central Hospital
Symptomatic Atherothrombosis
Antiplatelet Drug Resistances and Ischemic Events
The ADRIE study is an observational study on the clinical relevance of platelet reactivity in aspirin and clopidogrel treated cardiovascular patients.
- Trial name
- ADRIE (NCT00501423)
- Where
- France
- Volunteers
- 771 people
- Sponsor
- Pierre Fontana
Hypertension, Coronary Artery Disease
Candesartan for Prevention of Cardiovascular Events After Cypher or Taxus Coronary Stenting (4C) Trial
Candesartan is effective in preventing cardiovascular events in patients without restenosis after coronary angioplasty. Therefore, the investigators hypothesized that candesartan after drug-eluting stent (DES) implantation was…
- Trial name
- NCT00139386
- Testing
- Candesartan
- Where
- Japan
- Volunteers
- 1,119 people
- Sponsor
- Kumamoto University
Metabolic Syndrome, Cardiovascular Disease (CKD)
Tongmai Jiangtang Capsule for Cardiovascular Clinical Outcomes in High-Risk Metabolic Syndrome Patients
1. Conduct a large-sample, multicenter, superiority, double-blind, randomized controlled clinical trial to verify the efficacy of TJC in reducing the risk of cardiovascular and cerebrovascular events in patients with metabolic…
- Conditions
- Metabolic Syndrome, Cardiovascular Disease (CKD), Cerebrovascular Disease, Qi Deficiency and Blood Stasis
- Trial name
- TORCH-met (NCT06908473)
- Testing
- Participants will receive Tongmai Jiangtang Capsule (TJC) in addition to standard treatment.
- Where
- China
- Volunteers
- 530 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Carotid Artery Stenosis, Head and Neck Cancer
Carotid Artery Stenosis and Ischemic Cerebrovascular Events After Radiotherapy in Patients With Head and Neck Cancer
The study had a cross-sectional design and included patients with HNC involving the oral cavity, pharynx, larynx, nasal cavity, or salivary glands who recieve RT.
- Conditions
- Carotid Artery Stenosis, Head and Neck Cancer, Radiation Therapy, Transient Ischemic Attack
- Trial name
- RT-CASinHNC (NCT06556979)
- Testing
- Radiotherapy
- Where
- Thailand
- Volunteers
- 907 people
- Sponsor
- Chulabhorn Royal Academy
Type 2 Diabetes
Chronotherapy with Low-dose Aspirin for Primary Prevention
Brief summary: Aspirin (ASA) has been shown to provide marked benefits in primary and secondary prevention of cardiovascular events.
- Trial name
- CARING (NCT00725127)
- Testing
- aspirin
- Where
- 19 sites in Spain
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- University of Vigo
Venous Embolism of Lower Extremities (Diagnosis), Arterial Embolism and Thrombosis
Case-Specific Health Care Professional Clinical Survey of Liberant™ Thrombectomy System
The purpose of Case-Specific Health Care Professional (HCP) Clinical Survey of Liberant™ Thrombectomy System, also known as the Liberant Clinical Assessment, is to collect first-in-human clinical data to confirm the safety and…
- Conditions
- Venous Embolism of Lower Extremities (Diagnosis), Arterial Embolism and Thrombosis, Acute DVT of Lower Extremity, Chronic DVT of Lower Extremity
- Trial name
- NCT07335341
- Testing
- Liberant Thrombectomy System
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- Medtronic Endovascular
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