Clinical trials: Cardiovascular Health, open to volunteers
Hypertension, Diabetes Mellitus
Implementation of the COmmunity HEalth System InnovatiON Project in Low- and Middle- Income Countries
The COHESION-I project will evaluate the effects of the co-creation intervention (2016 to 2019) and the co-design intervention (2023 to 2024) on improving (a) health system responsiveness, and (b) patient satisfaction, at the…
- Conditions
- Hypertension, Diabetes Mellitus, Neglected Tropical Diseases
- Trial name
- COHESION-I (NCT06989502)
- Testing
- Co-creation (2016 to 2019) + Co-design (2023 to 2024), Co-design only (2023 to 2024)
- Where
- 3 sites in Mozambique, Nepal and 1 more
- Volunteers
- 2,094 people, healthy volunteers welcome
- Sponsor
- Universidad Peruana Cayetano Heredia
Myopia, Mental Health
Intervention for Preventing Myopia and Multimorbidity in Children
This study aims to develop and evaluate a scalable, hybrid intervention model for the co-prevention of myopia, obesity, and mental health issues among children.
- Conditions
- Myopia, Mental Health, Cardiovascular Health Status
- Trial name
- NCT07294222
- Testing
- Standard School Health Education, Multi-component Health Promotion Package
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Diabetes Mellitus, Type 2, Liver Fibrosis
Effect of an Early Time Restricted Eating Mediterranean Diet Compared to Naltrexone/Bupropion on Liver Fibrosis in People With Cardiometabolic Risk Factors in a Hospital Outpatient Clinic (MEDFAST-study)
In the Netherlands, there are many people with cardiometabolic diseases. More than half of these people also have fatty liver. This is a build-up of fat in the liver (steatosis) and can lead to long-term scarring (fibrosis) and…
- Conditions
- Diabetes Mellitus, Type 2, Liver Fibrosis, Liver Steatoses, Hepatic Steatosis
- Trial name
- MEDFAST (NCT06845345)
- Testing
- early time restricted Mediterranean diet, Mysimba
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Carmen Dietvorst
Dyslipidemia, Hypertension
Impact of a Produce Prescription Program and Nutrition Education Intervention on Cardiovascular Health in Youth
This study will assess the effect of a produce prescription program combined with nutritional classes on short and longer-term cardiovascular health in a cohort of children at risk for cardiovascular disease.
- Conditions
- Dyslipidemia, Hypertension, Obesity & Overweight
- Trial name
- NCT07545005
- Testing
- Nutrition education and produce prescription card
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Boston Children's Hospital
Diabetic Retinopathy
AI-Powered DIY Screening System for Diabetic Retinopathy
A pragmatic trial will be conducted in two representative clinics in each of the three types of targeted settings. It will be run for 3 months in each clinic to complete data collection of up to 100 patients in SPGC and Optometry…
- Trial name
- NCT06892353
- Testing
- AI-powered fundus camera screening
- Where
- Hong Kong
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Hereditary Angioedemas
A Study Investigating the Effectiveness and Safety of Garadacimab for Treating Patients With Hereditary Angioedema (HAE)
This is a multinational, multicenter, prospective, observational cohort study of patients with HAE in the real-world setting. The study will include patients newly initiating garadacimab in routine clinical practice.
- Trial name
- GREAT (NCT07001280)
- Testing
- No intervention
- Where
- 22 sites in United States, Austria and 3 more
- Volunteers
- 200 people
- Sponsor
- CSL Behring
Overweight , Obesity, Prediabetes
Smartwatch-based Intervention for Cardiovascular Health (SWITCH)
This study aims to employ a cluster randomized controlled trial to evaluate the effectiveness of an mHealth-Based Multi-faceted Cardiovascular Health Intervention Model among metabolically at-risk people with overweight/obesity…
- Conditions
- Overweight , Obesity, Prediabetes, High-normal Blood Pressure, Borderline Elevated Blood Lipids
- Trial name
- NCT07372729
- Testing
- Smartwatch-Based Multi-Faceted Behavioral Intervention Model Led by Exercise and Dietary Interventions, Supported by Primary Medical Staff, Along with the Distribution of Health Education Manuals, Face-to-face health education sessions
- Where
- 3 sites in China
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Stroke
SURA'A Campaign for Stroke Awareness in Primary Health Care Centers
This study aims to evaluate the effectiveness of a one-week multifaceted Stroke Urgency Recognition, and Action Awareness (SURA'A) consultation-based campaign in increasing stroke awareness and the intention to seek emergency…
- Trial name
- SURA'A (NCT07578259)
- Testing
- SURA'A Consultation-Based Campaign
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Chronic Heart Failure
Nurse-Led Education for Heart Failure Self-Care and Stability
Heart failure is a chronic condition that can lead to frequent hospitalizations and reduced quality of life. This study aims to evaluate whether a nurse-led, face-to-face educational intervention can improve clinical stability…
- Trial name
- EDUCATE (NCT07280728)
- Testing
- Nurse-Led Face-to-Face Educational Intervention (Teach-Back Method)
- Where
- Italy
- Volunteers
- 118 people
- Sponsor
- Azienda Socio Sanitaria Territoriale di Lodi
Multiple Myeloma
Follow-up of Patients With Multiple Myeloma in the West-Occitanie Region "Living With a Myeloma in West-Occitanie"
Actually very few real life data are available for patients with multiple myeloma (MM), whereas they're playing a more and more important role in health care decisions.
- Trial name
- VAMOS (NCT04888039)
- Testing
- quality of life questionnaires (EORTC QLQ-C30 ; EORTC QLQMY20 ; EQ-5D-5L ; Cohen's stress scale)
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Toulouse
Cardiac Diseases
Health Literacy As a Mediator Between Gender, Illness Identity, and Self-Efficacy
The goal of this observational study is to understand the role of health literacy in shaping the relationship between gender differences, illness identity, and self-efficacy in geriatric patients with cardiac diseases.
- Trial name
- NCT06707116
- Volunteers
- 100 people
- Sponsor
- Cairo University
Multisystem Inflammatory Syndrome in Children (MIS-C), SARS-CoV-2 Infection
Cardiovascular Assessment 5 Years After MIS-C
Multisystem inflammatory syndrome in children (MIS-C) is a severe complication associated with SARS-CoV-2 infection that frequently affects the cardiovascular system.
- Trial name
- NCT07659847
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Cardiovascular Health Risk Communication, Cardiovascular (CV) Risk
Breast Artery Calcification (BAC) and Female Cardiovascular Disease
The investigators are recruiting women with and without Breast Artery Calcification (BAC) on their mammograms. Each participant in the study will undergo bloodwork at a Northwell Health lab, a cardiac CT scan, and fill out some…
- Conditions
- Cardiovascular Health Risk Communication, Cardiovascular (CV) Risk, Cardiovascular Disease Prevention
- Trial name
- NCT07809932
- Testing
- Cardiac CT Scan, Bloodwork
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Healthy Pregnant Women, Obese Pregnant Women
Pregnancy Cohort Study: Pregnancy as a Window to Future Health
The goal of this observational cohort study is to gain deep insights into how metabolic disorders such as obesity or diabetes during pregnancy affect the metabolic and cardiovascular health of mother and child in the short and…
- Conditions
- Healthy Pregnant Women, Obese Pregnant Women, Gestational Diabetes
- Trial name
- PregWin (NCT06925815)
- Where
- Austria
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Cardiovascular Risk Factors, Cardiovascular Diseases
Cardiovascular Risk Factors in Mexican Women
Cardiovascular disease is a major cause of morbidity and mortality among women. Cardiovascular risk in women is influenced not only by traditional risk factors, but also by sex-specific factors and social determinants of health.
- Trial name
- REFARCAM Mx (NCT07863674)
- Where
- 3 sites in Mexico
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Medicaweb, S.A.C.V.
Hypertension, Hypertension Complicated
Improving Hypertension Control in Safety-Net Settings: The Boston Hypertension Equity Alliance in Treatment
High blood pressure (BP) or hypertension (HTN) affects over 100 million individuals in the US, increasing the risk of adverse outcomes, including stroke, myocardial infarction (MI), and chronic kidney disease (CKD).
- Trial name
- BHEAT (NCT06948838)
- Testing
- RBPM, MII
- Where
- 7 sites in United States
- Volunteers
- 16,895 people
- Sponsor
- Boston Medical Center
Atrial Fibrillation (Paroxysmal)
Biofeedback Intervention for Paroxysmal Atrial Fibrillation
This project aims to bridge the gap between technology and healthcare by developing a biofeedback intervention that enables daily monitoring of atrial fibrillation episodes and physical activity levels.
- Trial name
- BI-PAF (NCT07454317)
- Testing
- Biofeedback intervention
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Liverpool John Moores University