Clinical trials: Cardiovascular Risk
Foot Ulcer, Diabetic
Reliability of a Diabetic Foot Ulcer Risk Stratification and Referral Algorithm
The main objective of this research study is to validate the St Joseph's Health Care Harmonized Foot Ulcer Assessment and Stratification tool using inter-rater reliability technique to determine if the score would consistently be…
- Trial name
- NCT03370237
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hypertension
Cornell Translational Behavioral Science Research Consortium: Hypertension Qualitative Study
To explore the meaning, causes and treatment of hypertension in eligible patients. In addition the cultural, social, and psychological factors that either facilitate or serve, as barriers to behavioral change will be illuminated…
- Trial name
- NCT00227175
- Testing
- Semi-structured, open ended interview
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Weill Medical College of Cornell University
Body Composition, Visceral Obesity
Dysfunctional Adiposity and Glucose Impairment
This is a large and comprehensively phenotyped cohort with fasting glycaemia where the predictive value of body composition and anthropometric measures of total and central fat distribution for postprandial carbohydrate…
- Conditions
- Body Composition, Visceral Obesity, Carbohydrate Intolerance, Obesity, Abdominal
- Trial name
- DICAMANO (NCT03506581)
- Volunteers
- 853 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Type-2 Diabetes
Liraglutide and Cardio-Metabolic Risk Markers
Incretin-based therapies have shown significant effects beyond those on glucose metabolism. We aim in the present study to evaluate the effects of liraglutide on several cardio-metabolic risk markers.
- Trial name
- NCT01715428
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Palermo
Coronary Heart Disease, Susceptibility to, 5, Prediabetic State
Genetic Risk and Health Coaching for Type 2 Diabetes and Coronary Heart Disease
The purpose of this study is to examine whether the use of genetic test information and/or health coaching in patient risk counseling for heart disease and diabetes affect health behaviors and health outcomes in active-duty Air…
- Trial name
- NCT01884545
- Testing
- Health coaching, Genetic risk counseling, Standard risk assessment
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Duke University
Peripheral Vascular Disease
Lower Extremity Regional Anesthesia and Infrainguinal Bypass Grafting
In this investigation, the investigators will attempt to demonstrate that patients who have received nerve blocks (regional anesthesia) prior to open surgical vascular bypass of the lower extremities (infrainguinal bypass…
- Trial name
- NCT01803165
- Testing
- Single shot femoral and sciatic nerve block
- Sponsor
- University of Nebraska
Depression, Coronary Artery Disease
Effects of a Psychotherapy Intervention in Depressed Patients With Coronary Artery Disease
In patients with coronary artery disease (CAD), depressive symptoms are frequent and highly relevant for quality of life, health behaviour, health care costs, and prognosis.
- Trial name
- SPIRR-CAD (NCT00705965)
- Testing
- Psychotherapy, Information session, Usual cardiological care
- Where
- 10 sites in Germany
- Volunteers
- 570 people
- Sponsor
- University of Göttingen
Cardiovascular Diseases
Risk and Prevention Study: Evaluation of the Efficacy of n-3 PUFA in Subjects at High Cardiovascular Risk
In the everyday practice cardiovascular prevention in people at high risk is still unsatisfactory and treatments with documented efficacy are generally under-used.
- Trial name
- NCT00317707
- Testing
- N-3 Polyunsaturated Fatty Acids
- Where
- Italy
- Volunteers
- 12,513 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Heart Diseases
Training Methods for a Doctrine Of Life With Healthy Heart
This study is an interventional study which was conducted in the field. The investigators intended to develop an efficient and economically valuable method which can decrease the risk factors for prevention of cardiovascular…
- Trial name
- NCT00738231
- Testing
- Training
- Where
- Turkey (Türkiye)
- Volunteers
- 498 people
- Sponsor
- Eskisehir Osmangazi University
Heart Arrest
Automated Respiration Rate to Improve Accuracy of the Electronic Cardiac Arrest Risk Triage Score (eCART) Algorithm
Currently, breathing rate and heart rate are checked by nursing staff manually every few hours and entered into a patient's medical record.
- Trial name
- NCT02399930
- Testing
- Respiratory & Heart Rate Data Collection
- Where
- United States
- Volunteers
- 133 people
- Sponsor
- University of Chicago
Cardiovascular Diseases
Evaluating Electrocardiogram (ECG) Abnormalities From Young Adulthood Through Middle Age
An electrocardiogram (ECG) is a test that evaluates the electrical activity of the heart and can be used to detect heart problems.
- Trial name
- CARDIA ECG (NCT00556751)
- Where
- United States
- Volunteers
- 5,115 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Heart Disease
Clopidogrel Response Evaluation and AnTi-Platelet InterVEntion in High Thrombotic Risk PCI Patients
To identify the high-risk patients who might have in-stent thrombosis after PCI with thromboelastography and to head-to-head compare two intensified antiplatelet therapeutic strategies of double-dosage Clopidogrel and triple…
- Trial name
- CREATIVE (NCT01779401)
- Testing
- Clopidogrel 75mg, Clopidogrel 150mg, Aspirin 100mg
- Where
- 2 sites in China
- Volunteers
- 1,078 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Gender Incongruence, Cardiovascular (CV) Risk
Cardiovascular Health of Transgender Individuals During the Gender-affirming Pathway
Gender incongruence, now classified in ICD-11 as a "marked and persistent incongruence between an individual's experienced gender and the gender assigned at birth," is managed in dedicated, multidisciplinary centres that…
- Conditions
- Gender Incongruence, Cardiovascular (CV) Risk, Cardiovascular Disease Risk Factor, Cardiovascular Disease Acute
- Trial name
- CV-TGD (NCT07187947)
- Testing
- Feminizing GAHT, Masculinizing GAHT
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Heart Diseases, Hiv
Whole Food Plant-Based Diet for HIV-Associated Reduction in Cardiovascular Risk (PLANT-HART)
The goal of this clinical trial is to evaluate the impact of using a whole food plant-based diet in the reduction of cardiovascular risk related to HIV in people who live with HIV infection.
- Trial name
- PLANT-HART (NCT05796882)
- Testing
- Whole Food Plant-Based Diet Ad Libitum, Nutritional Standard Care
- Where
- Mexico
- Volunteers
- 10 people
- Sponsor
- Universidad Autonoma de Chihuahua
Obesity, Abdominal, Metabolic Syndrome
Omega-3 PUFA in Prevention of Cardiovascular and Metabolic Diseases (CARDMET3)
The study is aimed to assess the efficacy of animal, plant sources of omega-3 polyunsaturated fatty acids and omega-3 pharmacological supplements on obesity, metabolic syndrome and cardiovascular disease.
- Conditions
- Obesity, Abdominal, Metabolic Syndrome, Cardiovascular Risk Factor
- Trial name
- CARDMET3 (NCT04208308)
- Testing
- Chia seeds supplementation (25 g), Chia seeds supplementation (15 g), Combine supplementation: chia seeds (15g) and fish oil Maxi Cor 70+20
- Where
- Slovakia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Pavol Jozef Safarik University
Stroke, Ischemic, Cardiovascular Risk Factor
Development of a Prognostic Tool for the Stratification of Cardiovascular Risk in Patients With Ischemic Stroke
The availability of several high-cost strategies for the prevention of cardiovascular morbidity and mortality in patients with established cardiovascular disease highlights the necessity of reliable risk stratification of these…
- Conditions
- Stroke, Ischemic, Cardiovascular Risk Factor, Cardiovascular Diseases, Cardiovascular Morbidity
- Trial name
- NCT04189497
- Where
- Greece
- Volunteers
- 3,500 people
- Sponsor
- University of Thessaly
Venous Thromboembolism
High-Risk Factors for VTE Death
Study population and characteristics This retrospective cohort study initially screened 105,168 consecutive hospitalized patients at Shihezi People's Hospital from February 2022 to June 2025.
- Trial name
- NCT07767279
- Testing
- comorbidity, Respiratory Failure, Sepsis
- Where
- China
- Volunteers
- 105,168 people
- Sponsor
- China International Neuroscience Institution
Multiple Myeloma
ASCT in Combination With C-CAR088 for Treating Patients With Ultra High-risk Multiple Myeloma (MM)
This is a phase I/II, single-arm, open-lable study of autologous stem cell transplantation in combination with C-CAR088, an autologous BCMA CAR-T cell product, for patients with ulta high-risk multiple myeloma, defined as failed…
- Trial name
- NCT05632380
- Testing
- Autologous hematopoietic stem cell transplantation, C-CAR088
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Coronary Heart Disease, Anemia
The Role of Concomitant Diseases in Postoperative Complications Risk Stratification.
Study is conducted to assess the prevalence and structure of comorbidity among patients undergoing abdominal surgery and produce the stratification of the risk of postoperative complications by identifying independent predictors…
- Conditions
- Coronary Heart Disease, Anemia, Bronchial Asthma, Stroke
- Trial name
- STOPRISK (NCT03945968)
- Where
- 38 sites in Russia
- Volunteers
- 16,000 people
- Sponsor
- Russian Federation of Anesthesiologists and Reanimatologists
Hypertrophic Cardiomyopathy
Efficacy of Risk Assessment for Sudden Cardiac Death in Patients With Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a heart disease characterized by hypertrophy of the left ventricular myocardium and is most often caused by mutations in sarcomere genes.
- Trial name
- NCT04402268
- Testing
- Cardioverter-defibrillator
- Where
- Poland
- Volunteers
- 252 people
- Sponsor
- Poznan University of Medical Sciences