Clinical trials: Cardiovascular Risk Profile
Type 2 Diabetes, Cardiovascular Diseases
Effect of Liraglutide on the Metabolic Profile in Patients With Type 2 Diabetes and Cardiovascular Disease
In an unbiased metabolomics approach with subsequent pathway analyses, the current study seeks to examine the effect of Liraglutide treatment on the metabolic signature in treated patients as well as the effect of Liraglutide on…
- Trial name
- Lirabolic (NCT04057261)
- Testing
- Liraglutide Pen Injector [Victoza]
- Where
- Germany
- Sponsor
- RWTH Aachen University
Cardiovascular Disease, Bleeding
Lovaza's Effect on the Activation of Platelets
This study is to determine the effects of Lovaza in platelet function studies
- Trial name
- LEAP (NCT00515541)
- Testing
- Lovaza
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Invitrox
Cardiovascular Disease Risk Factor, Insulin Resistance
Acute Postprandial Effects of Functional Ice Cream With Cimarrón Bean Extrudate in Adults
The goal of this non-randomized clinical trial is to evaluate the acute postprandial metabolic effects of a functional ice cream enriched with Cimarrón bean (Phaseolus vulgaris L.
- Conditions
- Cardiovascular Disease Risk Factor, Insulin Resistance, Overweight (BMI > 25), Hyperglycaemia
- Trial name
- ICE-CBE-GLULIP (NCT07053267)
- Testing
- Funrional Ice Cream
- Where
- Chile
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Talca
Hypertriglyceridemia
Effects Of Consumption Of A Highly Mineralized Sodium Bicarbonated Water On Blood Lipid Profile
The aim of the study is to assess the beneficial effect of the short term consumption of the highly mineralized bicarbonated sodium water on blood lipid parameters compared to a low mineralized water.
- Trial name
- NCT01819636
- Testing
- sparkling highly mineral bicarbonated sodium water
- Where
- 3 sites in France
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Neptune
Arterial Stiffness, Oral Health
Predication of Arterial Stiffness in Healthy Adults by Oral Health and Chewing Assessments
INN.oral.HEALTH is an sub-study embedded in the Innsbruck Health Promotion Program (INN.HEALTH). The study investigates whether oral health, oral structure, and oral function provide additional information for understanding…
- Conditions
- Arterial Stiffness, Oral Health, Mastication, Deglutition
- Trial name
- INNoralHEALTH (NCT07736222)
- Testing
- Dentition and Occlusal Status Assessment, Oral Health Assessment Tool, Maximum Bite Force Measurement
- Where
- Austria
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Atrial Fibrillation
Hybrid Atrial Fibrillation Ablation Registry
Recently a combined approach of surgeon ablation in combination with endocardial ablation (hybrid ablation) has been introduced.
- Trial name
- NCT02516033
- Volunteers
- 250 people
- Sponsor
- University Medical Center Groningen
Cardiovascular Diseases, Atherosclerosis
Cardiovascular Risk Profile Among Mexican-Americans
To characterize the epidemiology and genetics of apolipoproteins A-I, A-II, B, C-II, C-III, and E in a population of Mexican-Americans in Starr County, Texas.
- Conditions
- Cardiovascular Diseases, Atherosclerosis, Heart Diseases
- Trial name
- NCT00005187
- Volunteers
- 2,058 people
- Sponsor
- The University of Texas Health Science Center, Houston
Carotid Atherosclerosis, Cerebrovascular Accident
Potential Risk Factors for Stroke
Early studies have shown that the immune system may play a role in the development of strokes. Conditions such as high blood pressure, high cholesterol, diabetes, and old age can activate the immune system and increase the risk…
- Conditions
- Carotid Atherosclerosis, Cerebrovascular Accident, Diabetes Mellitus, Hypercholesterolemia
- Trial name
- NCT00001368
- Testing
- cytokine and leukocyte activation profile
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Coronary Artery Disease, Arterial Stiffness, Blood Pressure
Expanded Studies on the SCAPIS Stockholm Reexamination Cohort
The Swedish CArdioPulmonary bioImage Study (SCAPIS) is a unique, large-scale national research initiative involving 30,000 randomly selected individuals aged 50-64, recruited between 2014 and 2018.
- Conditions
- Coronary Artery Disease, Arterial Stiffness, Blood Pressure, AORTIC VALVE DISEASES, Mitral Valve Stenosis and/or Insufficiency
- Trial name
- SCAPIS-ReEx (NCT07476703)
- Testing
- Coronary computer tomography (CCTA), Echocardiograhy and aortic ultrasound, Liver elastography
- Where
- Sweden
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Danderyd Hospital
Cardiovascular Risk Factor, Cardiovascular Diseases
Substituting Sitting With Standing and Walking in Free-living Conditions Improves Daily Glucose Profile in South Asians
The purpose of this study is to investigate the effects of substituting sitting under free-living conditions in South Asian adults with overweight and obesity on continuous glucose profiles.
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Diabetes, Type 2 Diabetes
- Trial name
- NCT04645875
- Testing
- SIT regimen, SITless regimen
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Bedfordshire
Cardiovascular Risk Factor, Metabolic Complication
Cold Water Immersion and Atherosclerosis, Inflammation, Fat Accumulation and Lipid Profile Parameters
The impact of the environment on human health is considerable. An important factor is the effect of temperature on the human body, where either the effects of short-term exposure to extreme temperatures (cryotherapy, sauna, etc.)…
- Conditions
- Cardiovascular Risk Factor, Metabolic Complication, Endocrine; Complications, Immune System Diseases
- Trial name
- NCT04642066
- Testing
- Cold water immersion, No cold water immersion
- Where
- Slovakia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pavol Jozef Safarik University
Endothelial Dysfunction, Cardiovascular Risk Factor
Intracoronary Features in the Prognosis of Endothelial Dysfunction and MACES in Population With Acute Coronary Syndrome
Coronary Artery Disease (CAD) is common in Mexico, while morbidity and mortality is high. Drug therapy can relieve angina pain and stabilize plaque, but it is not able to re-flow a coronary artery.
- Conditions
- Endothelial Dysfunction, Cardiovascular Risk Factor, Coronary Syndrome, Acute
- Trial name
- iphoneSPACE (NCT03583047)
- Where
- Mexico
- Volunteers
- 45 people
- Sponsor
- Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado
Gestational Hypertension, Cardiovascular Pregnancy Complication
Physical Activity and Cardiovascular Profile of Pre-conceptional Women At Risk for GHD
To compare the cardiovascular profile of pre-conceptional women at risk for developing Gestational Hypertensive Disorders in subsequent pregnancy before and after physical activity.
- Trial name
- SPORTY (NCT05888467)
- Testing
- supervised infrared exercise group, supervised non-infrared exercise group, Control group
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Hypertension
Irbesartan in Hypertension
Study objectives: To demonstrate the effect of irbesartan on the regulation of diastolic blood pressure, in case of missing one dose after a period of administration for 6 to 8 weeks To evaluate the safety of irbesartan
- Trial name
- NCT00265967
- Testing
- Irbesartan
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Sanofi
Diabetes Mellitus, Type 2
Immune Profile and Complication Risk in Type 2 Diabetes
The aim of this study is to investigate the relation between individual differences in pattern recognition molecules (PRM's) in the innate immune system and the prevalence and development of vascular complications in patients…
- Trial name
- IMPACT (NCT00674271)
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Multiple Myeloma
Study of FasT CAR-T GC012F Injection in High Risk TE NDMM Patients
This is a single-arm, single-center, open-label clinical study to evaluate the safety and efficacy of GC012F in high-risk, transplant eligible patients with NDMM.
- Trial name
- NCT04935580
- Testing
- GC012F injection
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Changzheng Hospital
Cardiovascular Diseases, Hypertension
ICA-CHAMP: Indo-Central Asian Cardiovascular Health Assessment and Management Program
Research has shown that the presence of heart disease and stroke is higher in the Indo-Asian population compared to other ethno-cultural groups.
- Conditions
- Cardiovascular Diseases, Hypertension, Hyperlipidemia
- Trial name
- ICA-CHAMP (NCT00627159)
- Testing
- High risk assessment, Low to moderate risk
- Where
- 2 sites in Canada
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Testicular Cancer, Seminoma
Cardiac Function and Cardiovascular Risk Profile in Testicular Cancer Patients
For many years, researchers and doctors have studied different kinds of treatments to improve the survival of men with testicular cancer.
- Conditions
- Testicular Cancer, Seminoma, Non-seminomatous
- Trial name
- NCT00705094
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- AHS Cancer Control Alberta
Endothelial Function (Reactive Hyperemia)
MOVING - MOtiVation, INtervention and Vascular chanGe
Background: The impact of demographic changes on workplace has increased the importance of effective occupational preventive health programs.
- Trial name
- MOVING (NCT01919632)
- Testing
- health-behavior seminar and endurance exercise
- Where
- 2 sites in Germany
- Volunteers
- 330 people
- Sponsor
- Technical University of Munich
Cardiovascular Diseases
Effects of the Mediterranean Diet on Cardiovascular Risk Profile in Men and Women (ALIMED)-Part 2
The purpose of this study is to document differences between men and women (referred here as gender differences) in diet adherence and in changes in specific dietary intakes and energy density in response to a 12-week nutritional…
- Trial name
- NCT01852721
- Testing
- Experimental: Men and Mediterranean diet, Experimental: Women and Mediterranean diet
- Where
- Canada
- Volunteers
- 123 people
- Sponsor
- Laval University