Clinical trials: Cardiovascular Shock
Sepsis, Septic Shock
Ascorbic Acid (Vitamin C) Infusion in Human Sepsis
The major goal of this project is to determine whether intravenously infused ascorbic acid is safe for use as a viable therapeutic strategy in adult humans with sepsis.
- Conditions
- Sepsis, Septic Shock, Hypotension, Acute Lung Injury
- Trial name
- NCT01434121
- Testing
- Ascorbic Acid
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Virginia Commonwealth University
Metastatic Cancers, Multiple Myeloma
Vertebral Augmentation and Radiotherapy of Collapse Spinal Metastatic Cancer
Vertebral augmentation with radiotherapy to increase the functional status and quality of life for patients with vertebral body metastatic cancers.
- Conditions
- Metastatic Cancers, Multiple Myeloma, Vertebral Fracture
- Trial name
- NCT02376933
- Testing
- Vertebroplasty, Radiotherapy
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Arizona
Septic Shock, Hypotension
Esmolol to Treat the Hemodynamic Effects of Septic Shock
The main purpose of this study is to determine the effects of controlling the heart rate of patients with septic shock using an intravenous medication called esmolol.
- Conditions
- Septic Shock, Hypotension, Tachycardia
- Trial name
- NCT02369900
- Testing
- Esmolol, Saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Beth Israel Deaconess Medical Center
Hypotension, Shock
Transcutaneous pO2, Transcutaneous pCO2 and Central Venous SO2 Variations to Define Fluid Responsiveness
Fluid challenge is often carried out in critical ill patients. Its responsiveness usually requires invasive monitoring. To use non-invasive methods is very tempting.
- Conditions
- Hypotension, Shock, Fluid Challenge, Fluid Responsiveness
- Trial name
- NCT01941472
- Testing
- fluid challenge
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking Union Medical College Hospital
Septic Shock, Sepsis
Phenylephrine Versus Norepinephrine for Septic Shock in Critically Ill Patients
Septic shock is a condition that is marked by severe infection causing hypotension requiring vasopressors to maintain adequate perfusion to vital organs.
- Conditions
- Septic Shock, Sepsis, Shock, Tachycardia
- Trial name
- NCT02203630
- Testing
- Phenylephrine, Norepinephrine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Vanderbilt University Medical Center
Chronic Disease, Neoplasm Metastasis
Facilitating Communication Study
This study is a randomized clinical trial of an intervention to improve outcomes for patients and their family by using ICU nurse facilitators to support, model, and teach communication strategies that enable patients and their…
- Conditions
- Chronic Disease, Neoplasm Metastasis, Lung Neoplasm, Pulmonary Disease, Chronic Obstructive
- Trial name
- FCS2 (NCT03721952)
- Testing
- Facilitator-Based Intervention
- Where
- 3 sites in United States
- Volunteers
- 977 people
- Sponsor
- University of Washington