Clinical trials: Cardiovascular Surgery
Heart Disease, Dietary Modification
Feeding Study - Effects Post-cardiac Surgery
The purpose of this randomized trial is to clarify the role of enteral nutrition (EN) on the relationship between cardiopulmonary bypass-induced inflammation and insulin resistance by investigating the effects of two different…
- Conditions
- Heart Disease, Dietary Modification, Insulin Resistance
- Trial name
- NCT02274220
- Testing
- Rapid advancement of feeds, Standard advancement of feeds
- Where
- Canada
- Volunteers
- 86 people
- Sponsor
- The Hospital for Sick Children
Intracerebral Hemorrhage, Brain Hemorrhage
PRONTO: Artemis in the Removal of Intraventricular Hemorrhage in the Hyper-Acute Phase
The purpose of this prospective, single center, single arm registry is to assess technical feasibility, peri-procedural complications, post-procedure imaging outcomes, and 30-day safety outcomes in subjects with intraventricular…
- Conditions
- Intracerebral Hemorrhage, Brain Hemorrhage, Intraventricular Hemorrhage
- Trial name
- PRONTO (NCT04178746)
- Testing
- Artemis Neuro Evacuation Device
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Penumbra Inc.
Cardiac Disease
Early Mobilisation of Post Cardiac Surgery in Geriatrics.
Heart and blood vessel problems together referred to as cardiovascular diseases (CVD) include congenital heart disease, cerebrovascular illness, and coronary heart disease.
- Trial name
- NCT06360146
- Testing
- Early mobilisation
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Hyperperfusion Syndrome, Moyamoya Disease
Sevoflurane and Hyperperfusion Syndrome
The aim of the present study is to evaluate the effect of sevoflurane postconditioning on the incidence of postoperative hyperperfusion syndrome following revascularization surgery in moyamoya patients.
- Trial name
- NCT02510586
- Testing
- Sevoflurane
- Volunteers
- 152 people
- Sponsor
- Seoul National University Hospital
Cardiovascular Risk Factors
Echocardiography Management for Patients Requiring Care for Non-Cardiac Surgery
The growing population of institution patients with heart failure combined with the increasing number of surgical procedures performed each year supports the need for a critical analysis of how to most appropriately manage these…
- Trial name
- EGHEM (NCT01050361)
- Testing
- Transthoracic Echocardiogram (TTE)/Transesophageal Echocardiogram (TEE)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Venous Insufficiency
Compression Therapy Versus Surgery in the Treatment of Superficial Venous Reflux
Randomized controlled trial, a method used to implement the random allocation sequence is numbered containers. The aim of the study is to compare compression therapy with compression stockings and surgery eliminating superficial…
- Trial name
- NCT01701661
- Testing
- Operative treatment, conservative treatment
- Where
- Finland
- Volunteers
- 153 people
- Sponsor
- Helsinki University Central Hospital
Heart Surgery
Association Between S-LAAO and Adverse Cardiovascular Events Among Patients Undergoing Coronary Artery Bypass Grafting.
This is a prospective, single-center, randomized, active controlled, clinical trail to assess the efficacy and safety of surgical closure of left atrial appendage (LAA) in patients undergoing coronary artery bypass graft.
- Trial name
- NCT04108169
- Testing
- Left atrial appendage occlusion surgery
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Beijing Institute of Heart, Lung and Blood Vessel Diseases
Coronary Artery Disease
Effectiveness of Early Cardiac Rehabilitation
The goal of this experimental study is to compare the effects of early (2nd week) cardiac rehabilitation applied in addition to usual care on functional capacity, quality of life, frailty and body composition in patients…
- Trial name
- NCT06116773
- Testing
- Training, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Cardiovascular Complications, Myocardial Infarction
Ankle-Brachial Index Estimating Cardiac Complications After Surgery
Introduction: Patients undergoing noncardiac surgery are at increased risk of cardiovascular complications. The development of methods that can accurately predict the occurrence of these events is of critical importance and large…
- Conditions
- Cardiovascular Complications, Myocardial Infarction, Acute Coronary Syndromes
- Trial name
- ABRACOS (NCT01452282)
- Where
- Brazil
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Acute Myocardial Infarction (AMI), Percutaneous Coronary Intervention (PCI)
BRIDGE Trial: Embedding Consumer-grade mHealth Technologies Into Cardiac Rehabilitation
The purpose of the BRIDGE study is to learn whether supplementing traditional center-based cardiac rehabilitation (CBCR) with a mobile health technology intervention can help patients monitor their health, stay engaged in healthy…
- Conditions
- Acute Myocardial Infarction (AMI), Percutaneous Coronary Intervention (PCI), Coronary Artery Bypass Graft Surgery (CABG), Chronic Heart Failure With Reduced Ejection Fraction (HFrEF)
- Trial name
- BRIDGE (NCT07741396)
- Testing
- CBCR, BRIDGE mHealth intervention
- Volunteers
- 30 people
- Sponsor
- University of Illinois at Chicago
Peripheral Vascular Disease, Critical Limb Ischemia
Near Infrared Spectroscopy and Transcutaneous Oxygen Pressure in Critical Limb Ischemia Before and After Treatment
Comparison of two non-invasive methods for measuring tissue oxygenation. One is Transcutaneous Oxygen Pressure (TCPO2) and the other is the new method of Near Infrared Spectroscopy (NIRS) - near infrared spectroscopy in patients…
- Trial name
- NIRS (NCT01459341)
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Carmel Medical Center
Aortic Valve Stenosis
PremiCron Suture for Cardiac Valve Repair
The study is a voluntary study, initiated by B. Braun to collect clinical data for PremiCron® suture concerning its key indication.
- Trial name
- PremiValve (NCT04096859)
- Where
- 2 sites in Germany, Spain
- Volunteers
- 198 people
- Sponsor
- Aesculap AG
Venous Thromboembolism
Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Major Abdominal Surgery
The primary objective is to compare the efficacy and safety of once daily (q.d.) subcutaneous (s.c.) injections of Semuloparin sodium (AVE5026) with q.d. s.c.
- Trial name
- SAVE-ABDO (NCT00679588)
- Testing
- Semuloparin Sodium, Enoxaparin sodium
- Where
- 270 sites in United States, Argentina and 37 more
- Volunteers
- 4,413 people
- Sponsor
- Sanofi
Cardiac Disease
Ice Bag, TR Band, and Air Compression Effects on Radial Line Removal Outcomes in Open Heart Surgery: A Clinical Trial
The study aims to find the different effects of applying an ice-bag pressure, TR radial band compression device-screw type, and TR radial band compression device-air type on early complications and comfort among patients…
- Trial name
- NCT06705361
- Testing
- Transparent Radial Artery Band (Screw-Type)
- Where
- Iraq
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Gastric Cancer, Venous Thromboembolism
Incidence of Venous Thromboembolism Following Surgery in Patients With Gastric Cancer
Venous thromboembolism (VTE) has considerably harmful effects on morbidity and mortality of cancer patients. Several guidelines recommendations have been made about the use of anticoagulation for the prevention and treatment of…
- Conditions
- Gastric Cancer, Venous Thromboembolism, Postoperative Period
- Trial name
- NCT01345773
- Testing
- Gastric surgery
- Where
- South Korea
- Volunteers
- 375 people
- Sponsor
- Seoul National University Bundang Hospital
Coagulation Protein Disorders, Blood Loss, Surgical
Observational Study of Prophylaxis and Treatment of Acute Perioperative Bleeding With Beriplex® P/N (Probe Study)
Beriplex® P/N is made from human plasma (the liquid part of the blood) and contains the coagulation factors II, VII, IX and X which are important for blood clotting (coagulation).
- Conditions
- Coagulation Protein Disorders, Blood Loss, Surgical, Perioperative Care
- Trial name
- NCT01053169
- Testing
- Beriplex® P/N, Fresh Frozen Plasma (FFP) and Beriplex® P/N, Fresh Frozen Plasma
- Where
- 6 sites in United Kingdom
- Volunteers
- 445 people
- Sponsor
- CSL Behring
Peripheral Arterial Disease
Advanta VXT and Flixene PMCF Registry
The purpose of the registry is to evaluate the long-term safety and performance of Advanta VXT and Flixene vascular grafts for repair or replacement of peripheral arteries.
- Trial name
- NCT07161583
- Testing
- Advanta VXT Vascular Graft, Flixene Vascular Graft
- Where
- 2 sites in United States, France
- Volunteers
- 1,000 people
- Sponsor
- Atrium Medical Corporation
Coronary Artery Disease, Antiplatelet Therapy
Minimally Invasive Coronary Artery Bypass Supported by Cangrelor
The purpose of this study is to find out whether it is safe and practical to perform MIDCAB surgery (a minimally invasive heart bypass procedure) while patients receive a continuous cangrelor infusion during the operation.
- Conditions
- Coronary Artery Disease, Antiplatelet Therapy, Minimally Invasive Coronary Revascularization Surgery
- Trial name
- MINOTAUR (NCT07514962)
- Testing
- Cangrelor-guided MIDCAB surgery (for the prospective cases), Aspirin MIDCAB surgery (for the historical controls)
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Cardiocentro Ticino
Peripheral Vascular Disease
A Prospective Study to Assess the Screening Value of N-terminal Pro-B-type Natriuretic Peptide (NT-proBNP) for the Identification of Patients That Benefit From Additional Cardiac Testing Prior to Vascular Surgery
The purpose of this study is to validate the screening potential of NT-proBNP for the identification of patients scheduled for vascular surgery who would benefit from additional pre-operative cardiac testing.
- Trial name
- NCT00519961
- Testing
- Elecsys®proBNP
- Where
- 2 sites in Ireland, Netherlands
- Volunteers
- 1,800 people
- Sponsor
- Hoffmann-La Roche
Atrial Fibrillation
Safety and Efficacy Study of The Combined Ablation Procedure To Treat Longstanding Persistent Atrial Fibrillation
This is a multi-center, prospective open label, feasibility study evaluating the safety and efficacy of the combined ablation procedure for the treatment of longstanding persistent atrial fibrillation.
- Trial name
- CAPstopsLSPAF (NCT01103661)
- Testing
- Numeris®-AF Guided Coagulation System with VisiTrax®
- Where
- 4 sites in United States
- Volunteers
- 7 people
- Sponsor
- nContact Surgical Inc.