Clinical trials: Care Management, Patient
1. Obesity
Effectiveness of Brief Counseling for Weight Management
The purpose of this study is to test the effectiveness of three different methods for delivering weight management information. Two methods utilize an obesity drug and the third method utilizes brief behavioral counseling…
- Trial name
- NCT00212199
- Testing
- orlistat, Brief cognitive behavioral counseling
- Where
- United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes Mellitus, Non-Insulin-Dependent
OPtimal Type 2 dIabetes Management Including Benchmarking and Standard Treatment in CEEMEA
OPTIMISE-CEEMEA is a multinational, multi-centre, observational, prospective study which will include patients suffering from diabetes type 2, treated or untreated, insulin dependent or not insulin dependent.
- Trial name
- OPTIMISE (NCT01694758)
- Where
- 20 sites in Bulgaria, Romania
- Volunteers
- 733 people
- Sponsor
- AstraZeneca
Pain, Postoperative, Patient Comfort
Effect of Virtual Reality on Pain, Comfort and Satisfaction
The goal of this clinical trial is to examine the effect of virtual reality application on pain management, comfort, and care satisfaction in patients undergoing thyroidectomy-parathyroidectomy.
- Conditions
- Pain, Postoperative, Patient Comfort, Patient Satisfaction, Thyroidectomy
- Trial name
- NCT06199687
- Testing
- Use of Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Trakya University
Bariatric Surgery, Postoperative Complications
National Emergency Bariatric Surgery Audit
The goal of this observational study is to investigate the incidence, management, and outcomes of complications following bariatric surgery in patients in the United Kingdom.
- Conditions
- Bariatric Surgery, Postoperative Complications, Emergencies, Surgical Procedures, Operative
- Trial name
- NEBSA (NCT06738004)
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- Bedfordshire Hospitals NHS Foundation Trust
Acute Kidney Injury, Renal Insufficiency, Acute
VExUS-guided Fluid Management in Patients With Acute Kidney Injury in the Intensive Care Unit
A quasi experimental study that aims to verify whether the incorporation of VExUS in patients with AKI in the Intensive Care Unit (ICU) may prompt tailored interventions to increases the number of days free from Renal Replacement…
- Conditions
- Acute Kidney Injury, Renal Insufficiency, Acute, Kidney; Disease, Acute, Critical Illness
- Trial name
- AKIVEX (NCT05240833)
- Testing
- VExUS Score
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Heart Failure, Congestive, Coronary Arteriosclerosis
After Discharge Management of Low Income Frail Elderly
The purpose of this study is to determine whether comprehensive post-hospitalization interdisciplinary care management can be an effective care delivery model to improve outcomes in low-income frail elderly.
- Conditions
- Heart Failure, Congestive, Coronary Arteriosclerosis, Atrial Fibrillation, Cerebrovascular Accident
- Trial name
- NCT00328848
- Testing
- Behavioral
- Volunteers
- 530 people
- Sponsor
- Summa Health System
Severe Mental Illness
Care Coordination and Passive Mobile Data Monitoring to Improve Mental Health Care
Providing care to individuals with serious mental illness can be challenging, requiring ongoing monitoring, treatment adjustments, and coordination of various medical and social services.
- Trial name
- CCM (NCT07549178)
- Testing
- Care Coordination Mobile
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- VA Office of Research and Development
Dementia, Alzheimer Disease
Care Ecosystem: Navigating Patients and Families Through Stages of Care, Extension Trial
This is an extension trial of a prior trial (NCT02213458). Both persons with dementia (PWD) and their caregivers were enrolled as dyads.
- Conditions
- Dementia, Alzheimer Disease, Dementia, Vascular, Lewy Body Disease
- Trial name
- NCT04287738
- Testing
- Navigated Care
- Volunteers
- 912 people
- Sponsor
- University of California, San Francisco
HIV Infections, AIDS
A Randomized Clinical Trial to Evaluate Solutions for the Management of Virologic Failure on TLD in Sub-Saharan Africa
The RESOLVE trial is an open, parallel arm, randomized clinical trial which aims to determine the optimal strategy for management of virologic failure on antiretroviral therapy (ART) with tenofovir, lamivudine, and dolutegravir…
- Conditions
- HIV Infections, AIDS, Virologic Failure
- Trial name
- RESOLVE (NCT05373758)
- Testing
- Standard of Care treatment strategy, Individualized Care treatment strategy, Immediate Switch
- Where
- 3 sites in South Africa, Uganda
- Volunteers
- 648 people
- Sponsor
- Massachusetts General Hospital
Health Behavior, Motivation
Measuring Anticipated Attitudes and Behavior Towards a New Medical Treatment in Lesotho
The primary research objective is to examine how uncertainty towards a new medical treatment changes in patients when a partner (can be any close other, i.e.
- Conditions
- Health Behavior, Motivation, Health Care Utilization, Consumer Behavior
- Trial name
- NCT06246058
- Testing
- Partner support, Formal recruiter attire, Without Partner support
- Where
- Lesotho
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Diabetes Mellitus, Type 2
Reusing Needles for Subcutaneous Insulin Injection in Patients With Type 2 Diabetes
A randomized clinical trial (RCT) will be carried out to compare the reuse or not of needles in patients with type 2 diabetes (T2DM) that use insulin.
- Trial name
- NCT05407233
- Testing
- Does not reuse the syringe for insulin application, Uses the syringe for insulin delivery five times
- Where
- Brazil
- Volunteers
- 71 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pain, Pain Management
Individualized Analgesia in the Intensive Care Unit With a New Pain Assessment Bundle and Protocolized Analgesia Adjustments
Both severe pain and opioid therapy are associated with negative effects. The experience of pain is common in the intensive care unit, but it is highly individual and difficult to assess, as patients are often unable to…
- Conditions
- Pain, Pain Management, Critical Illness
- Trial name
- INVISIBLE (NCT07473115)
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University of Zurich
Autism Spectrum Disorder
Gaming Open Library for Intervention in Autism at Home (GOLIAH /MICHELANGELO)
To meet the required intensive intervention hour for treating children with autism spectrum disorder (ASD), the investigators developed an automated serious gaming platform (11 games) to deliver intensive intervention at home…
- Trial name
- MICHELANGELO (NCT02560415)
- Testing
- Experimental, Comparator
- Volunteers
- 24 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
GI Cancer, Lymphoma
Geriatric Communication Skills Training Program for Oncology Clinicians
The purpose of this study is to learn more about the effects of a training program designed to help doctors communicate better with older patients and their caregivers.
- Conditions
- GI Cancer, Lymphoma, GU Cancer, Bone Marrow Transplant
- Trial name
- NCT03530969
- Testing
- Self-Efficacy Assessment, UCLA Geriatrics Attitudes Scale, Course Evaluations
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Multimorbidity
Living With Multimorbidity: Care Coordination and Symptom Management Program (COORDINATE)
The goal of this clinical trial is to learn if a new care program, called the COORDINATE Program, can help older adults with two or more chronic health conditions.
- Trial name
- NCT07157982
- Testing
- COORDINATE Program, Enhanced Usual Care
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Johns Hopkins University
Aherence, Physical Symptoms
The Effectiveness of Augmented Reality to Enhance CPAP Therapy in OSA Patients
The goal of this clinical trial is to exam if artificial reality works to improve continuous positive airway pressure (CPAP) adherence in obstructive sleep apnea (OSA) patients.
- Conditions
- Aherence, Physical Symptoms, Mental Health, Quality of Life
- Trial name
- CPAP OSA (NCT06520592)
- Testing
- With AR guided CPAP therapy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Cheng-Kung University Hospital
Venous Thromboembolism, Digital Health
Smart Technology Facilitated Patient-centered Venous Thromboembolism Management
Smart technologies, such as wearable devices, mobile technologies, and artificial intelligence, are being investigated for use in health management.
- Conditions
- Venous Thromboembolism, Digital Health, Health Education
- Trial name
- SmaVTE-COR (NCT06350344)
- Testing
- mobile venous thromboembolism application (mVTEA)
- Where
- China
- Volunteers
- 2,353 people
- Sponsor
- Navy General Hospital, Beijing
Hemorrhagic Strokes, Postoperative Hypertension
A Comparison of Nicardipine and Labetalol for Blood Pressure Control in Intensive Care Patients After Hemorrhagic Stroke Brain Surgery
Patients with hemorrhagic stroke who undergo brain surgery (craniotomy) often experience high blood pressure after surgery. Poor blood pressure control can increase the risk of bleeding, brain injury, and other serious…
- Conditions
- Hemorrhagic Strokes, Postoperative Hypertension, Hemodynamic Instability
- Trial name
- NIC-LAB ICU (NCT07364201)
- Testing
- Nicardipine, Labetalol
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Universitas Sumatera Utara
Patients With Septic Shock, Surgical Patients
Dobutamine for Management of Surgical Patients With Septic Shock
Septic shock is the last and most severe stage of sepsis and is defined by extremely low blood pressure, despite lots of intravenous fluids. The incidence of septic shock related cardiomyopathy was 10% to 70%.
- Conditions
- Patients With Septic Shock, Surgical Patients, General Anesthesia
- Trial name
- NCT06462313
- Testing
- Dobutamine, Norepinephrine
- Where
- China
- Volunteers
- 584 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Intensive Care Unit
Noninvasive Hemoglobin Monitoring by Spectrophotometry in Blunt Abdominal Trauma Patients for Conservative Management
We aimed to study the efficacy of Noninvasive Hemoglobin Monitoring by Spectrophotometry in monitoring hemoglobin level in trauma patients for conservative management.
- Trial name
- NCT05171296
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
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