Clinical trials: Care Management, Patient
Blood Loss, Surgical, Coagulation Disorder
Phase 3 Trial of Reltodecacog Alfa (VMX-C001) vs Usual Pharmacological Care in Patients Taking a FXa Direct Oral Anticoagulant Who Require Urgent Surgery With or Without Heparin.
The goal of this clinical trial is to learn if reltodecacog alfa (VMX-C001) works to to allow blood clotting control in participants who take FXa Direct Oral Anticoagulants (DOACs) during surgery or other invasive procedures that…
- Trial name
- EQUILIBRIX-S (NCT07288489)
- Testing
- Reltodecacog alfa, Usual Pharmacological Care
- Where
- 77 sites in United States, Australia and 16 more
- Volunteers
- 800 people
- Sponsor
- VarmX B.V.
Supportive Care, Cancer
Feasibility Study of the Advanced Symptom Management System (ASyMS) in Canadian Cancer Patients
The Advanced Symptom Monitoring and Management System - Canada (ASyMS-Can) is a remote phone-based symptom management system that prompts patient self-care and clinician telephone triage and intervention based on alerts for…
- Trial name
- ASyMS-Can (NCT03335189)
- Testing
- ASyMS-Can
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- University Health Network, Toronto
Inflammatory Bowel Diseases, Ulcerative Colitis
Improving Patient Outcomes Through the Implementation of an IBD Biologic Care Pathway
Inflammatory Bowel Disease (IBD) includes a group of chronic inflammatory conditions of the gastrointestinal system and is composed of Crohn's disease and ulcerative colitis.
- Conditions
- Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
- Trial name
- NCT06030882
- Testing
- Biologic Care Pathway
- Where
- Canada
- Sponsor
- Jennifer Jones
Metabolic Syndrome (MetS)
Use of a Mobile Application for Tracking Physical Activity in the Management of Metabolic Syndrome in Primary Care
This study will explore whether integrating a mobile app to track physical activity-recommended by family doctors during routine primary care visits-can help individuals with metabolic syndrome become more active.
- Trial name
- IMAFIL (NCT07236450)
- Testing
- Mobile Application and Wearable Device for Physical Activity Monitoring
- Where
- Portugal
- Volunteers
- 100 people
- Sponsor
- Andreia Lobo
Mental Disorders, Severe
Transmural Collaborative Care Model for CVRM and Medication Review for Patients Using Antipsychotics
Currently, monitoring of usage and effects of antipsychotic treatment and cardiovascular risk screening in patients with severe mental illness or antipsychotic treatment is not sufficient.
- Trial name
- TACTIC (NCT05647980)
- Testing
- TACTIC
- Where
- Netherlands
- Volunteers
- 480 people
- Sponsor
- Radboud University Medical Center
Heart Failure,Congestive, Mental Health (Depression)
Evaluation of Nurse-led Integrated Care of Complex Patients Facilitated By Telemonitoring: The SMaRT Study
In Canada, 3 out of 4 Canadians aged 65 and older have at least one chronic condition, while 1 in 4 seniors reported having three or more.
- Conditions
- Heart Failure,Congestive, Mental Health (Depression), Diabetes Mellitus, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT05543720
- Testing
- Medly
- Where
- 4 sites in Canada
- Volunteers
- 350 people
- Sponsor
- University Health Network, Toronto
Stroke
Guideline-recommended Basic Parameter Adherence in Neurocritical Care Patients
The aim of the planned study project is to assess the current situation regarding the treatment of patients with severe stroke at the neuro-critical care unit.
- Trial name
- NORMONICU (NCT06367543)
- Testing
- Time in therapeutic range of vital parameters
- Where
- Germany
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Metastatic Renal Cell Carcinoma
Impact of the PRISM-care Multidisciplinary Oncology Program on Secured Drug Intake of Patients With Kidney Cancer
The rise of oral targeted therapies favors outpatient care of cancer patients but exposes them to new risks compared to the injectable chemotherapy in the hospital: non-adherence to treatment, inappropriate management of side…
- Trial name
- PRISM care (NCT02849535)
- Testing
- PRISM care program
- Where
- 12 sites in France
- Volunteers
- 190 people
- Sponsor
- Hospices Civils de Lyon
Iron-deficiency
ProPBM : A Modified Patient Blood Management Protocol
The introduction of a modified perioperative patient blood management protocol with intravenous iron intervention for iron deficiency anaemic patients would reduce the need for allogenic blood transfusion and reduce perioperative…
- Trial name
- NCT03888768
- Testing
- MonoFer
- Where
- Malaysia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Malaysia
Sickle Cell Disease
Patient-Provider Tools to Improve the Transition to Adult Care in Sickle Cell Disease
The purpose of the study is to develop patient-provider clinical support tools to improve clinical practice, patient self-management, and disease outcomes in sickle cell disease during transition to adult care.
- Trial name
- iTransition (NCT02200510)
- Testing
- Self-management intervention for Adolescents with SCD, Patient Portal Intervention for Adolescents with SCD
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Wound
Povidone-Iodine Versus Chlorhexidine in Surgical Wound Care
This comparison examines the effectiveness of povidone-iodine and chlorhexidine in managing iatrogenic wounds in surgical patients.
- Trial name
- NCT06667089
- Testing
- Povidone-Iodine, Chlorhexidine
- Where
- Spain
- Volunteers
- 107 people
- Sponsor
- University of Jaén
Chronic Disease
Classification of Patient Therapeutic Education Programs Components : Etude CONCErTo
Interest in patient therapeutic education (PTE) is increasing: in France PTE was included within the 2009 "Hospital, Patient, Health and Territory" law as an essential component of the patient healthcare pathway.
- Trial name
- CONCErTo (NCT02717182)
- Testing
- interviews
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
Hypertriglyceridemia
Vitamin C Administration and Triglycerides Level in Critical Care Patients
Vitamin C (ascorbic acid) is a water-soluble vitamin with antioxidant properties. Previous studies showed that the administration of vitamin C was associated with decreased triglyceride (TG) levels in ambulatory patients…
- Trial name
- NCT06206759
- Testing
- administration of vitamin C
- Where
- Israel
- Volunteers
- 2,000 people
- Sponsor
- Meir Medical Center
Ovarian Cancer
Individualised Versus Conventional Medical Follow-up for Women After Primary Treatment for Ovarian Cancer.
The purpose of this study in women who have completed primary treatment for ovarian cancer is to investigate the effects of individualised follow-up care delivered by a nurse compared to conventional medical follow-up on quality…
- Trial name
- NCT02298855
- Testing
- Individualised follow-up
- Where
- 3 sites in United Kingdom
- Volunteers
- 113 people
- Sponsor
- University College, London
Pain, Postoperative
An Efficacy and Safety Study to Compare Fentanyl Ionsys and Routine Care With Intravenous (IV) Morphine Patient-controlled Analgesia (PCA) in Participants Who Have Undergone Elective Major Abdominal or Orthopedic Surgery
The purpose of this study is to evaluate the mobilization characteristics, clinical use, safety and Ease of Care (EOC) of a fentanyl Iontophoretic Transdermal Patient Controlled Analgesia (PCA) system (Ionsys) and morphine…
- Trial name
- NCT00766506
- Testing
- Fentanyl IONSYS, Morphine IV PCA
- Where
- 7 sites in United Kingdom
- Volunteers
- 108 people
- Sponsor
- Janssen-Cilag Ltd.
Pain, Pain, Postoperative
Peter Hess® Sound Massage for Reducing Anxiety and Pain in Cardiac Surgery
Cardiac surgery patients often undergo anxiousness and pain. Before surgery, anxiety is often caused by the idea of sternotomy, extracorporeal circulation, fear of post-operative pain, and even death.
- Conditions
- Pain, Pain, Postoperative, Pain, Chest, Anxiety
- Trial name
- MuSoCa (NCT05204043)
- Testing
- Peter Hess® sound massage, Music relaxation Music Care®, Questionnaires
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Surgical Procedures, Elective, Nurse Based Care Management
The Effect of White Noise Sleep Mask on Patients' Sleep Quality and Comfort After Transurethral Resection of the Prostate (TUR-P) Surgery
One of the greatest challenges patients face in the postoperative period is the deterioration of sleep quality. Decreased sleep quality in the postoperative period is commonly observed due to pain, stress, anxiety, hospital…
- Trial name
- NCT06936384
- Testing
- In this group, patients will be provided with a white noise sleep mask in accordance with the protocol determined for the postoperative period. Patients will sign an informed voluntary consent form be
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Other Cancer
Shared Care: Patient-Centered Management After Hematopoietic Cell Transplantation
This research study aims to evaluate the effectiveness of allowing patients who have had a hematopoietic cell transplant to receive some of their post-transplant care with a local oncologist rather than returning to the…
- Trial name
- NCT03244826
- Testing
- Shared Care, Standard Care
- Where
- 9 sites in United States
- Volunteers
- 404 people
- Sponsor
- Dana-Farber Cancer Institute
Serious Emotional Disturbance of Youth
Development and Testing of an Electronic Behavioral Health Record Specific to the Wraparound Care Coordination Process
The purpose of this Phase II Small Business Technology Transfer (STTR) project is to complete development and evaluate usability and effectiveness of the Wraparound Team Monitoring System (Wrap-TMS), a web-based, electronic…
- Trial name
- NCT02421874
- Testing
- Wraparound Team Monitoring System electronic health record, Education about fidelity maintenance and monitoring
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Washington
Critical Illness, Pediatrics
Effect of Giving Reduced Fluid in Children After Trauma
This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid…
- Conditions
- Critical Illness, Pediatrics, General Surgery, Fluid Therapy
- Trial name
- NCT04201704
- Testing
- Balanced crystalloid solution volume administration, Packed Erythrocytes Units, Blood Product Unit volume, Plasma volume
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- Columbia University
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