Clinical trials: Caries, Dental
Cardiac Disease, Dental Caries
Saliva Profiles in Children With Congenital Heart Disease
The purpose of this study was to evaluate whether there are relationships between the salivary oxidative stress status of children with CHD directly dental caries including gender, age, salivary flow rate, salivary pH, salivary…
- Trial name
- NCT03457974
- Testing
- saliva
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University
HIV Infections
A Study to Compare the Effectiveness of a Four Drug Anti-HIV Regimen Given Alone or in Combination With GM-CSF or IL-12 to HIV-Positive Patients
The purpose of this study is to examine how the level of HIV is reduced in the blood when anti-HIV therapy is initiated. This study will also evaluate whether adding GM-CSF or IL-12 to the anti-HIV drug regimen will increase the…
- Trial name
- NCT00000896
- Testing
- Indinavir sulfate, Lamivudine/Zidovudine, Hepatitis A Vaccine (Inactivated)
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cavity, Cavities of Teeth
In Vivo Assessment of the Tooth-Resin Composite Interface Using Optical Coherence Tomography
The aim of the study is to compare the short-term marginal integrity of two preparation techniques for Class I composite restoration using two visual assessment techniques, the FDI World Dental Federation and US Public Health…
- Trial name
- NCT05145322
- Testing
- Composite with 90 degree cavosurface angle, Composite with wide bevel
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Minnesota
Dental Caries in Children
Toothbrushing Program in Saudi Arabia "TOPS"
Project summary Introduction: Dental caries is a major oral health problem worldwide and is a particular public health challenge in Saudi Arabia. Dental caries cause pain, infection, and negatively impact quality of life.
- Trial name
- NCT05512156
- Testing
- Supervised Toothbrushing
- Where
- Saudi Arabia
- Volunteers
- 588 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Dental Caries, Tooth Fractures
Comparison of Conventional and CAD/CAM Dental Restorations
Dental restorations (crowns, inlays or onlays) can be made conventionally or by CAD/CAM. The current literature is weak and does not separate the medical results of these two techniques.
- Conditions
- Dental Caries, Tooth Fractures, Tooth Resorption
- Trial name
- EVACFAOD (NCT02494427)
- Testing
- CAD/CAM manufactured fixed unitary dental prostheses, Conventionally manufactured unitary dental prostheses
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cavities of Teeth
Esthetics of Dental Composite and Adhesive System
To compare a newly developed filling composite to a current filling composite system. Two restorations will be placed in each subject, one using system A and one using system B.
- Trial name
- NCT03716349
- Testing
- Pulp vitality testing, Photos, local and/or topical anesthetic
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Erica Teixeira
Dental Caries
Does Administration of Probiotics During Infancy Increase the Caries Risk of a Child
Aim: to examine caries occurrence in children who ten years ago received a mixture of probiotics during infancy. Hypothesis: the administration of probiotics during infancy has no effect on future dental health.
- Trial name
- NCT01424852
- Testing
- Probiotics in infant milk formula
- Where
- Finland
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Turku
Dental Caries
Postoperative Pulpal Complications in Posterior Resin Composite Restorations Without Glass-ionomer Cement Lining
The purpose of this study is to observe the effects of glass-ionomer cement (GIC) lining on risk of pulpal complications in deep occlusal cavities with resin-based restorations.
- Trial name
- NCT01567514
- Testing
- Glass ionomer cement lining
- Where
- Thailand
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Dental Caries
A Pilot Study to Promote Maternal and Infant Oral Health
The long term goals of this project are to develop and implement a combined prenatal and postnatal intervention to decrease early childhood caries. The program is based on risk assessment, diet intervention and counseling.
- Trial name
- NCT00719238
- Testing
- Nutrition plus education, Education only
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- UConn Health
Early Childhood Caries, Dental Caries
Great Beginnings for Healthy Native Smiles: An Early Childhood Caries Prevention Project
The purpose of this study is to determine whether a bundled best practices oral health intervention utilizing motivational interviewing versus a didactic maternal and child healthy lifestyle intervention will reduce childrens'…
- Trial name
- NCT04556175
- Testing
- Oral Health, Healthy Lifestyle
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Anxiety, Dental, Dental Decay
A Comparison of Oral Sedation-related Events of Three Multiagent Oral Sedation Regimens in Pediatric Dental Patients
This study will compare the post sedation events from three different multi-drug oral sedation regimens in order to help pediatric dentists determine the best course of action for their patients and prepare parents appropriately…
- Trial name
- NCT05126459
- Testing
- Regimen 1, Regimen #2, Regimen #3
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Loma Linda University
Dental Caries
Polymer Induced Liquid Precursor (PILP) in Adults in With Dentin Caries
The goal of this clinical trial is to learn if polymer-induced liquid precursor (PILP) can be used safely to treat dentin caries (cavities) in adults.
- Trial name
- NCT06727110
- Testing
- PILP Cement, PILP Conditioner
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Dental Caries in Children
Potential for Dentine Discoloration of Silver Diamino Fluoride Associated With Potassium Iodide
The objective of this randomized clinical trial will be the comparison of dentine discoloration after treatment with: Silver Diamino Fluoride and Silver Diamino Fluoride associated with Potassium Iodide for caries lesions in…
- Trial name
- NCT04001959
- Testing
- Silver Diamine Fluoride with Potassium Iodide
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Dental Caries
Oral Health Assessment of Children in CP Class
Few oral exams are performed on 6-year-olds (key age for carious disease). This project aims to increase the number of oral check-ups for 6-year-olds in fragile areas (REP/REP+ areas).
- Trial name
- NCT04795258
- Where
- France
- Volunteers
- 671 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Dental Caries
Randomized Clinical Trial of Occlusal Sealant
This study assessed long-term impact of tooth Eruption Stages (ES) on sealant retention on occlusal surfaces previously coated with intermediary bonding layer and it determined caries incidence outcome evolved.
- Trial name
- NCT02589743
- Testing
- Sealant, Adhesive and Sealant
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Extensive Decay in Primary Molars
Comparison of The Success Rates of Four Different Pulpotomy Techniques
This randomized clinical trial was conducted to examine and compare the effectiveness of pulpotomy in primary molars treated with calcium silicate based materials including Biodentine and two different mineral trioxide aggregate…
- Trial name
- NCT03135626
- Testing
- Biodentine, ProRoot (Aggregate), MTA Plus
- Volunteers
- 38 people
- Sponsor
- Istanbul University
Dental Caries
Oral-Spray Bacillus Spore Probiotic in Preventing and Supporting Treatment of Dental Caries in Children
Despite advances in oral health care, cavities remain highly prevalent worldwide, especially among children. Conventional treatment methods focus on removing damaged tooth tissue but fail to completely eliminate or control…
- Trial name
- NCT07241052
- Testing
- oral-spray 0.9% NaCl physiological saline solution, Smile Care
- Where
- Vietnam
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Anabio R&D
Dental Caries
Effects of Different Remineralization Agents on the Progression of Non-Cavitated Approximal Carious Lesions in Primary Teeth: A Randomized Clinical Trial
Dental caries is a highly prevalent disease in children. Contemporary caries management emphasizes minimally invasive approaches that aim to arrest or reverse non-cavitated lesions rather than remove tooth structure.
- Trial name
- REMİN-PRİMARY (NCT07431463)
- Testing
- P11-4 + NaF Varnish, Silver diamine fluoride, NaF Varnish Alone
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Izmir Katip Celebi University
Class III Dental Caries
Clinical Performance of Glass-hybrid in the Treatment of Class III Restorations
This is a double blinded, split mouth, randomized clinical study that evaluated the performance of a glass hybrid restorative material in class III lesions.
- Trial name
- Class-III (NCT05843734)
- Testing
- Equia forte HT
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Class V Dental Caries, High Caries Risk Patients
Clinical Evaluation of Different Bioactive Restorative Materials for Cervical Carious in High Caries Risk Patients
The aim of the study is to clinically evaluate three different bioactive restorative material in cervical carious lesion in high caries risk patients. Reducing the incidence of recurrent caries is the primary outcome
- Trial name
- NCT06736964
- Testing
- Giomer
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
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