Clinical trials: Caries, Dental
Dental Caries
Evaluation of Implants Placed Immediately or Delayed Into Extraction Sites
IRB4729 Study Hypothesis: Is there a significant difference in the hard and soft tissue response comparing immediate with delayed implant after tooth removal, with immediate provisionalization, in maxillary anterior sites.
- Trial name
- NCT01244997
- Testing
- Dental Implant
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Dental Caries, Dentin Sensitivity
Comparative Evaluation of the Post Operative Sensitivity of Cention-N(Commercially Available Restorative Material) Using Conventional and Polymer Bur- In-vivo Study
Cention-N(commercially available restorative material) is a cost effective restoration for posterior restorations. Post-operative sensitivity is of great concern as far as any type of restorative material is concerned.
- Trial name
- NCT05185206
- Testing
- Class 1 cavity preparation using conventional steel bur and restoration with Cention-n(commercially available restorative material)., Class 1 cavity preparation using polymer bur and restoration with Cention-n(commercially available restorative material).
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dr. D. Y. Patil Dental College & Hospital
Dental Caries, White Spot Lesions
QLF and Digital Imaging for Caries Activity Assessment After Orthodontic Treatment
This prospective longitudinal observational study aims to evaluate the diagnostic performance and agreement of Smartphone photography, intraoral 3D imaging, Quantitative Light-Induced Fluorescence Digital (QLF-D), and ICDAS…
- Conditions
- Dental Caries, White Spot Lesions, Caries Lesion Activity, Post-Orthodontic Enamel Demineralization
- Trial name
- NCT07608471
- Volunteers
- 30 people
- Sponsor
- Universidad El Bosque, Bogotá
Dental Caries
Clinical Evaluation of a Self-etch Adhesive Using a Selective Etch Technique
Study hypothesis: Etching the enamel followed by use of a self-etching adhesive on enamel and dentin is as effective as a one-step etch and rinse approach.
- Trial name
- NCT01369134
- Testing
- Adper Easy Bond Self-etch dental adhesive
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Solventum US LLC
Caries,Dental, Apical Periodontitis
Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - Pediatric
The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine…
- Trial name
- NCT03962634
- Testing
- Kovanaze Nasal Spray, Articaine Injection
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Virginia Commonwealth University
Caries, Periodontitis
Diagnosis of Common Oral Diseases by Signature Volatile Profiles
Oral diseases tend to be exacerbated due to delayed diagnosis. Patients avoid visiting their dentist even for regular checkups, and develop late stage disease, jeopardizing the treatment outcome.
- Trial name
- NCT02931032
- Testing
- Sampling of dental plaque / infected dentine
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Primary Ciliary Dyskinesia, Caries,Dental
Assessment of Oral Health Status of Children With Primary Ciliary Dyskinesia
The aim of this study is to compare the oral health findings, salivary parameters and pediatric oral health related quality of life of children with Primary Ciliary Dyskinesia (PCD) with healthy children
- Conditions
- Primary Ciliary Dyskinesia, Caries,Dental, Quality of Life, Saliva Altered
- Trial name
- NCT06618209
- Testing
- physical and chemical methods, biochemical methods, Oral Findings
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dental Pulp Disease
Manual and Rotatory Instrumentation Pulpectomy in Primary Mandibular Molars
In this study, the aim is to compare manual and rotatory pulpectomy techniques on 100 primary mandibular molars on children between the ages of 4 and 8 years.
- Trial name
- RotaPulp (NCT04636450)
- Testing
- Rotatory technique pulpectomy, Manual pulpectomy
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Universidad de Guanajuato
Dental Caries
Consumption Effect of Probiotic Products on Salivary Cariogenic Bacterial Counts in Preschool Children.
The purpose of this study is to evaluate the efficacy of probiotic products on caries-associated salivary bacterial counts (Streptococcus mutans and Lactobacillus) and its effect on dental plaque accumulation in a group of…
- Trial name
- NCT02692625
- Testing
- (L. reuteri Prodentis®).
- Where
- Saudi Arabia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Caries in Children, Satisfaction
Comparison of Caries Arrested & Prevented Among SDF, NaF Varnish and Combination in Children
Tooth decay is one of the most common chronic infectious disease found in children worldwide and if left untreated, is rapidly progress.
- Conditions
- Dental Caries in Children, Satisfaction, Cost Effectiveness, Oral Health
- Trial name
- NCT03480516
- Testing
- SDF, Fluoride varnish
- Where
- Thailand
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Patients With Deep Carious Lesions
Clinical Evaluation and Microbiological Assessment of Diode Laser and Chemical Disinfection in Comparison to Selective Caries Removal
Objectives: To evaluate the clinical and antimicrobial effect of Diode laser and chemical disinfection in comparison to selective caries removal in management of deep carious lesions.
- Trial name
- NCT03955341
- Testing
- Diode laser disinfection, Chemical disinfection using 2% Chlorhexidine
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Misr International University
Dental Caries
Comparison of Two Universal Composites in Posterior Teeth
The aim of this randomized, prospective clinical study was to compare the clinical performance of a universal light-curing, ultra-fine particle hybrid composite with a new version of this product produced by the same manufacturer…
- Trial name
- NCT02888873
- Testing
- Charisma, Charisma Classic
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries in Children
Effectiveness of Teleorientation in Oral Hygiene During the COVID-19 Pandemic
The present study aims to evaluate the effectiveness of Teleorientation in oral hygiene during Pandemic by COVID-19 in children aged 6 to 10 years, attended at the Pediatric Clinic of Forp.
- Trial name
- NCT04967794
- Testing
- Teleorientation and Tooth Brushing Orientation
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Pulpitis - Reversible, Occlusal Caries
Evaluation of Cytokines Level as an Indicator of Pulp Inflammation and Its Relation to the Success Rates of Pulpotomy in Primary Molars Affected With Proximal Versus Occlusal Decay
pulpotomy will be done I primary molars with occlusal or proximal decay and level of cytokines will be measured as an indicator for pulp inflammation levels
- Conditions
- Pulpitis - Reversible, Occlusal Caries, Proximal Caries
- Trial name
- NCT07171229
- Testing
- Pulpotomy, Measuring Cytokines level
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Cairo University
Dental Caries
Caries-preventive Effect of a Dentifrice Containing 5,000 Ppm Fluoride in Orthodontic Patients
AIM: To evaluate the efficacy of daily tooth brushing with high concentrated fluoride dentifrice on white spot lesion (WSL) formation in adolescents during treatment with fixed orthodontic appliances (FOA).
- Trial name
- NCT01768390
- Testing
- toothpaste containing 5,000 ppm fluoride, 1450 GCP
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- University of Copenhagen
Dental Caries in Children, Cariostatic Agent
Cariostatic and Remineralizing Effects of Three Different Dental Varnishes
This study is a randomly, controlled, prospective in vivo study. The objective of this study is: To evaluate the cariostatic and re-mineralizing effects of Nano silver fluoride, Nano Hydroxyapatite and sodium fluoride varnishes…
- Conditions
- Dental Caries in Children, Cariostatic Agent, Resistance, Dental Caries, Fluoride Varnishes
- Trial name
- NCT04887389
- Testing
- Nano Silver Fluoride varnish, nano-hydroxyapatite varnish, sodium Fluoride Varnish
- Where
- Egypt
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Nisreen Ibrahim khan
Molar Incisor Hypomineralization, Enamel Hypoplasia
Resin Infiltration Treatment for MIH
The investigators aimed to evaluate changes in mineralisation degree, colour, and size of the lesion after Icon® in permanent teeth with MIH in 6 months.
- Conditions
- Molar Incisor Hypomineralization, Enamel Hypoplasia, Enamel Caries, Anterior Teeth
- Trial name
- NCT04685889
- Testing
- Resin infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Class IV Dental Caries
Clinical Performance of Two Different Bevel Preparations in Class IV Lesions Using Nanofilled Composite
The purpose of the study is to compare and evaluate clinical performance between two different bevel preparations in Class IV lesions using nano-filled composite restorations.
- Trial name
- NCT06220890
- Testing
- Tooth preparation in Class IV lesions with 2mm bevel, Tooth preparation in Class IV lesions with 2mm stair-step chamfer
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Cavities of Teeth
An Evaluation of Protective Effects of OpalSeal™ Against Early Dental Decay in Orthodontic Patients
Fluoride is very effective in preventing dental decay (cavities) when applied in the form of a varnish on tooth surfaces. The purpose of this study is to verify if fluoride-releasing primer (OpalSeal) offers more protection…
- Trial name
- NCT03722264
- Testing
- OpalSeal, TransbondXT
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Virginia Commonwealth University
Dental Caries
Clinical Performance of Fiber Reinforced FRC Base and Bonded CAD/CAM Resin Composite Endocrowns
This research proposal is introduced to clinically test short fiber reinforced flowable resin composite material (everX Flow, GC Europe) as a supporting base under CAD/CAM resin composite endocrowns due to gap of knowledge…
- Trial name
- NCT06348979
- Testing
- Fiber flowable (SFRC) support below hybrid nanoceramic endocrowns, all ceramic Endocrowns (emax)
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cairo University
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