Clinical trials: Caries, Dental
Root Canal Therapy
Clinical Applicability of PBSCIMMO as a Single Material in Endodontic Obturations
A randomized, interventional, prospective, unicentric clinical study, 86 patients will be submitted to endodontic treatment of necrotic teeth.
- Trial name
- PBSCIMMO (NCT03514264)
- Testing
- Gutta Percha and AHPLUS cement (group A), PBS CIMMO cement (group B)
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Tooth Decay
Preformed Pediatric Crown Zirconia Versus Preformed Pediatric Metal Crown
Preformed metal pediatric crowns (PPCm) are currently considered the best method of restoring Primary molars affected by severe carious lesions compared to restorations made with various restorative materials (amalgams…
- Trial name
- PPC Z-M (NCT03296709)
- Testing
- PPC z, PPC m
- Where
- 4 sites in France
- Volunteers
- 101 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Dental Caries
Children's Comfort With Isolite and Rubber Dam During Dental Treatment
Effective isolation is essential for successful restorative dental treatment in children because it improves moisture control, treatment quality, and patient safety.
- Trial name
- COMFORT (NCT07718412)
- Testing
- Isolite, Rubber Dam Isolation
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Cumhuriyet University
Dental Caries
Performance of GIOMER Based Resin Composite
The aim of the study is to clinically evaluate the performance of GIOMER based resin composite restorations versus conventional nanohybrid resin composite restorations in complex proximal carious cavities in posterior teeth over…
- Trial name
- NCT06021028
- Testing
- complex proximal carious cavities in posterior teeth.
- Where
- Egypt
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Cairo University
Badly Decayed Teeth andTeeth Restored With Large Filling Restorations and Endodontically Treated Teeth and Malformed Teeth and Malposed Teeth
Clinical Evaluation of Internal Fit of Milled BioHPP Polyetheretherketone (PEEK) - Based Versus Zirconia-Based Single Crowns
All ceramic crowns are indicated in case of mild to moderate discoloration, restoration of traumatized or fractured teeth and abnormal tooth anatomy.
- Trial name
- NCT04052789
- Testing
- BioHPP PEEK copings veneered with composite resin
- Volunteers
- 16 people
- Sponsor
- Cairo University
Patients With Deep Carious Lesions, Deep Caries Lesion of Pemanent Teeth
A Comparative Clinical Study Assessing Dentin Thickness and Discoloration in Deep Carious Lesions Treated With Biodentine Alone Versus Diode Laser Pre-treatment Followed by Biodentine
This interventional clinical study aims to compare dentin thickness preservation and tooth discoloration in deep carious lesions treated with Biodentine alone versus diode laser pre-treatment followed by Biodentine.
- Conditions
- Patients With Deep Carious Lesions, Deep Caries Lesion of Pemanent Teeth, Deep Carious Lesion
- Trial name
- NCT07358442
- Testing
- Biodentin, Diode laser
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Misr International University
Dental Caries
Comparison of Silver Modified and Conventional Atraumatic Restorative Treatment Modalities
The study is a randomized controlled trial aiming to compare the effectiveness of Silver modified atraumatic restorative technique and (SMART) and conventional atraumatic restorative technique (ART) regarding their caries…
- Trial name
- NCT03881020
- Testing
- Silver diamine Fluoride 38%, Conventional atraumatic restorative treatment
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
White Spot Lesion of Tooth, Long Term Adverse Effects
Comparison of Efficacy Of Probiotic Toothpaste and Chlorhexidine Mouthwash To Reduce S.Mutans
Orthodontic appliance causes increase in plaque accumulation, especially around brackets, wires and attachments. Advances in orthodontics in recent time have led to improved quality of appliance and treatment procedures…
- Conditions
- White Spot Lesion of Tooth, Long Term Adverse Effects, Caries, Dental, Orthodontic Appliance Complication
- Trial name
- NCT03004196
- Testing
- Probiotic Toothpaste, Dr. Reddy's Clohex, Control Group
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peoples University, Bhanpur, Bhopal
Dental Caries
Dental Caries Management by Risk Assessment: Identification and Treatment of Risk Factors Among (IDF) Personnel
Our study is designed as an interventional prospective longitudinal study which examines the Israeli defense force personnel. The population of our study is composed out of the IDF personnel which will be randomly be subdivided…
- Trial name
- CAMBRA (NCT01142440)
- Testing
- behavioral intervention
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Caries, Dental
Comparing Hall vs Conventional Technique in Placing Preformed Metal Crowns From Sudan
Preformed metal crowns (PMCs) have high success rates in restoring primary molars in children but they were not generally used by dentists, especially in developing countries due to its demand of high clinical skills with the…
- Trial name
- NCT03640013
- Testing
- Hall Technique PMC
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Khartoum Centre for Research and Medical Training
Dental Caries in Children
Discoloration of Carious Primary Teeth After Application of Silver Diamine Fluoride Versus Sodium Fluoride Varnish
To assess discoloration of carious primary teeth after application of silver diamine fluoride versus sodium fluoride varnish.
- Trial name
- NCT03557996
- Testing
- Silver Diamine Fluoride, Sodium Fluoride Varnish
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oral Health Related Quality of Life (OHRQoL), Early Childhood Caries (ECC)
Assessment of Oral Health-Related Quality of Life in Preschool-Aged Children in Alto Alentejo
The observational study aims to improve understanding of Oral Health-Related Quality of Life (OHRQoL) among preschool children in the District of Portalegre, Portugal, by examining the roles of sociodemographic, behavioral, and…
- Conditions
- Oral Health Related Quality of Life (OHRQoL), Early Childhood Caries (ECC), Traumatic Dental Injuries, Gingivitis
- Trial name
- NCT07648121
- Where
- Portugal
- Volunteers
- 454 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Dental Caries
Dietary Analysis for Caries Prevention in Children Using a Computer Software
Children will be recruited from the pediatric dentistry clinic of Marquette University at their first or recall appointment and will be asked to fill a questionnaire regarding their dietary habits.
- Trial name
- NCT02375763
- Testing
- Software instruction
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marquette University
Class III Dental Caries
Clinical Performance of Glass-hybrid in the Treatment of Class III Restorations
This is a double blinded, split mouth, randomized clinical study that evaluated the performance of a glass hybrid restorative material in class III lesions.
- Trial name
- Class-III (NCT05843734)
- Testing
- Equia forte HT
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Cervical Caries
Clinical Performance of Bioceramic vs High Viscosity GIC for Cervical Restorations of Geriatric Patients
The aim of this study is to clinically evaluate the performance of the bioceramic glass ionomer compared to conventional high viscosity glass ionomer for restoration of carious cervical lesions in geriatric patients over 12…
- Trial name
- NCT05624008
- Testing
- Bioceramic glass ionomer restoration, Resin modified glass ionomer restoration
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Caries, Dental
Remineralization Effects of Hydroxyapatite Toothpaste
The objective of this in situ clinical study is to determine whether a toothpaste containing hydroxyapatite microclusters is as effective as a fluoridated kid's toothpaste in promoting remineralization of early caries lesions and…
- Trial name
- NCT03681340
- Testing
- Hydroxyapatite toothpaste, Fluoridated toothpaste
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Dr. Joachim Enax
Dental Caries
Efficacy of Hall Technique in Atypical Lesions on Primary Teeth
Atypical carious cavities could be defined as carious lesions in more than 2 surfaces of the same tooth. Dental practitioners have shown difficulties related to material's maintenance in such type of cavities and therefore…
- Trial name
- SLM2078 (NCT02782390)
- Testing
- Dental Restoration with Stainless Crown, Dental Restoration with Composite Resin
- Where
- Brazil
- Volunteers
- 364 people
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Dental Caries Class II
A Clinical Assessment of Glass Carbomer Cement
This study will evaluate the clinical performance of glass carbomer cement restorations in restoring proximal lesions in primary molars compared to that of resin modified glass ionomer cement and composite resin restorations.
- Trial name
- NCT03030690
- Testing
- Glass Carbomer Cement, Composite Resin, Resin Modified Glass Ionomer Cement
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Caries, Caries Risk
Validation of a Digital Caries Risk Assessment Questionnaire Against the CAMBRA Protocol in an Egyptian Adult Population
This study is designed as a cross-sectional diagnostic agreement study conducted in accordance with the Standards for Reporting Diagnostic Accuracy Studies (STARD 2015) and the Guidelines for Reporting Agreement and Precision of…
- Trial name
- NCT07716254
- Testing
- Digital Caries Risk Assessment
- Where
- Egypt
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Dental Caries
The Behaviour of Dental Nurses Applying Fluoride Varnish to Young Children
The behaviour of 12 dental nurses seeing 600 nursery school children in East Scotland will be video-taped to determine the interaction patterns adopted by the staff in the application of a fluoride varnish to the surfaces of the…
- Trial name
- BEHAVE (NCT00881790)
- Testing
- Fluoride varnish
- Where
- United Kingdom
- Volunteers
- 509 people, healthy volunteers welcome
- Sponsor
- University of St Andrews
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