Clinical trials: Caries, Dental
Dental Caries
Impact of Atraumatic Restorative Treatment and Oral Health Promotion on Psychological and Salivary Aspects of Children
This study evaluated the impact of atraumatic restorative treatment associated with oral health educational strategy on dental anxiety, oral health-related quality of life and salivary biochemical and microbiological…
- Trial name
- NCT03100773
- Testing
- Oral health educational strategy, Atraumatic Restorative Treatment
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Dental Anxiety, Children, Only
Effect of Parental Absence on Child's Dental Anxiety and Behaviors During Dental Treatment
The basis of pediatric dentistry is to provide cooperation in children with various behavioral management techniques. The presence or absence of the parent during dental treatments can be used to ensure the child's compliance…
- Conditions
- Dental Anxiety, Children, Only, Dental Caries
- Trial name
- NCT05125731
- Testing
- Parental absence, Parental visual support, Parental presence
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Caries; Initial, Occlusal Caries
Early Treatments for Preventing Occlusal Caries Lesions
Sealants effectively arrest non-cavitated caries lesions on the fully erupted occlusal surface of permanent teeth. However, the clinical effectiveness of sealants is uncertain in preventing occlusal caries lesions in partially…
- Conditions
- Caries; Initial, Occlusal Caries, Caries,Dental
- Trial name
- NCT05969756
- Testing
- Fluoride varnish, Conventional etch and rinse sealant, Self-etch sealant
- Where
- 2 sites in Vietnam
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hue University of Medicine and Pharmacy
Dental Caries Extending to Pulp, Molar Incisor Hypomineralization
Vital Pulp Therapy in Carious Teeth With Hypomineralization
Vital pulp therapy (VPT) is a general term for multiple procedures (indirect pulp cap, direct pulp cap and pulpotomy) all directed toward preserving pulp vitality and enable complete root development in immature teeth.
- Trial name
- NCT03735069
- Testing
- IPT (Indirect pulp treatment), Cvek/partial pulpotomy, Cervical pulpotomy
- Where
- Jordan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Dental Caries, Pulpitis
Comparison of Mineral Trioxide Aggregate (MTA) and 20% Formocresol (FC) in Pulpotomized Human Primary Molars
This prospective clinical randomized controlled trial is established to compare the clinical, radiographic, and histological treatment outcomes between MTA and FC in pulpotomized human primary molars at 6, 12, 18, 24 month…
- Trial name
- NCT00972556
- Testing
- Gray Mineral Trioxide Aggregate (GMTA), Diluted (20%) Formocresol (DFC)
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Dental Caries Class II
Clinical Performance of a Glass-ionomer Restorative System in Extended-sized Cavities
The aim of this clinical trial was to compare the clinical performances of a glass ionomer restorative system with a micro hybrid resin based composite in extended sized class II cavities.
- Trial name
- NCT02991664
- Testing
- Equia Forte, G-aenial Posterior
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Mutans Streptococci, Xerostomia
Xylitol Disk Use in Adults With Dry Mouth
The purpose of this study is to demonstrate whether decay causing bacteria are reduced when adhesive xylitol disks are used intraorally three times a day for two weeks in adults with dry mouth.
- Trial name
- NCT01823445
- Testing
- Xylitol disk
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Washington
Malnutrition, Child
Chronic Malnutrition and Oral Health Status in Children Aged One to Five Years
Malnutrition is a public health problem that can exert a negative impact on the general and oral health of children. The aim of the present study was to evaluate the effect of chronic malnutrition on the oral health of children…
- Trial name
- NCT03529500
- Testing
- Caries detection - dmtf index, Saliva flow rate, Saliva Buffering Capacity
- Where
- Brazil
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Severe Early Childhood Caries, Dental Caries
Salivary Antimicrobial Peptides and Severe Early Childhood Caries in Turkish Children
This observational study aims to evaluate the relationship between salivary antimicrobial peptides and severe early childhood caries (S-ECC) in Turkish children.
- Trial name
- NCT07414030
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Dental Caries
SDF With or Without Fluoride Varnish for Caries Arrest in Primary Teeth of Young Children
Tooth decay (dental caries) occurs when acids dissolve tooth structure. If not treated, cavities in primary teeth can progress quickly, leading to caries, infection and early tooth loss.
- Trial name
- SDF-FV (NCT07153328)
- Testing
- Silver Diamine Fluoride (SDF, 38%) and Sodium Fluoride Varnish (NaF, 5%), Silver Diamine Fluoride (SDF, 38%)
- Where
- 2 sites in Albania
- Volunteers
- 104 people
- Sponsor
- Beaty Dent
Dental Wear, Dental Decay
Effect of Modeling Resin on Anterior Direct Composite Veneer
the study will be conducted to evaluate the clinical performance of direct Nanohybrid resin composite veneer restorations applied with or without modeling resin
- Trial name
- NCT06485024
- Testing
- Modeling Resin
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Plaque, Dental Caries
Probiotic Treatment of Orthodontic Patients
The purpose of this study is to examine the effect of treatment with a lozenge containing the probiotic strain S. salivarius M18 on the formation, composition and virulence of dental plaque and in healthy orthodontic patients…
- Trial name
- NCT06751979
- Testing
- Probiotic treatment
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Early Childhood Caries
Effectiveness of Dental Caries Arrest Treatment in Primary Teeth Using AgNO3 Followed by NaF Varnish
Aim: This randomised controlled trial will systematically compare the efficacy of a 25% AgNO3 solution followed by 5% NaF varnish with that of a 38% SDF solution in arresting caries teeth among preschool children when applied at…
- Trial name
- NCT02019160
- Testing
- 25% AgNO3 solution followed by 5% NaF varnish
- Where
- China
- Volunteers
- 1,070 people
- Sponsor
- The University of Hong Kong
Tooth Decay
Comparing the Clinical Success of Two Different CAD/CAM Full Cuspal Coverage Onlays
This is a single-center, ten-year, randomized controlled, split-mouth clinical trial. A total of 164 adult patients requiring full-cuspal coverage onlays will be enrolled.
- Trial name
- CUSTOM (NCT07519382)
- Testing
- full cuspal covarage onlay
- Where
- Hungary
- Volunteers
- 164 people
- Sponsor
- Semmelweis University
Oral Health
A Model-based Health Education Program to Improve Oral Health in School Going Children
This was a randomized controlled trial to assess how an education program based on health belief model (HBM) may affect oral health status in the elementary school going children.
- Trial name
- NCT05112224
- Testing
- Education program based on health belief model to improve oral health
- Where
- Iran
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Baqiyatallah Medical Sciences University
Autism Spectrum Disorder, Dental Caries
Using Video Modeled Social Stories to Improve Oral Hygiene in Children With Autism Spectrum Disorder
We hypothesize that oral hygiene habits in children 8-12 years of age can be improved using video format Social Story intervention techniques.
- Trial name
- NCT02003820
- Testing
- video modeled social story
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Yale University
Dental Caries in Children, Dental Caries
Improving Dental Health Among Toddlers in the Dominican Republic
Caries prevalence in the Dominican Republic (DR) seems high, although recent information is lacking. In DR there is a growth and development program for all children from the age of 0 to 5.Even though there is a mandatory…
- Trial name
- NCT04101617
- Testing
- Oral Health education including printed educational material
- Where
- Dominican Republic
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Universidad Iberoamericana
Dental Caries
Efficacy of Sealing Molars: Split-mouth Randomized Clinical Trial
The sealing of fossae and fissures is an effective procedure in preventing occlusal caries lesions. However, there are gaps regarding its efficacy in the treatment of initial enamel lesions.
- Trial name
- NCT03819868
- Testing
- High cost, Low Cost
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Dental Caries in Children
SDF for the Management of Dental Caries in Children in Primary Dental Care: Protocol for a Feasibility Study
Dental caries remains a significant health problem in England, effecting 11% of 3-year-olds and 23% of 5-year- olds. Children with dental caries suffer pain, infection and poor oral health-related quality of life.
- Trial name
- NCT06092151
- Testing
- Silver diamine fluoride, Usual dental care
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
White Spot Lesions
P11-4 and Fluoride Varnish for Remineralization of Post-orthodontic Lesions
This clinical study aims to compare the remineralizing effects of self-assembling peptide P11-4 (SAP11-4) with fluoride varnish in the treatment of post-orthodontic non-cavitated carious lesions (NCLs).
- Trial name
- NCT06749977
- Testing
- Remineralization with SAP11-4, Remineralization with sodium fluoride varnish
- Where
- Bulgaria
- Volunteers
- 45 people
- Sponsor
- Medical University of Sofia
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