Clinical trials: Caries, Dental
Dental Caries
A Clinical Trial to Assess the Retention and Caries Preventive Effect of Resin Based Sealants Versus ART Sealants
Background and study aims: The investigators are carrying out a clinical trial of two different sealant materials to compare the retentivity and decay inhibiting properties of the above said materials.
- Trial name
- NCT02408601
- Testing
- Helioseal - F, ART sealant
- Where
- India
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Dr. Praveen B.H
Dental Caries in Children
Clinical and Radiographic Evaluation of Injectable Composite Versus Packable Composite in Restoring of Primary Molars
This randomized clinical trial aims to compare the clinical and radiographic performance of injectable composite versus packable composite in restoring cavitated primary molars in children aged 4 to 8 years.
- Trial name
- NCT07239154
- Testing
- packable composite, injectable composite
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Eslam samy abdel monaem kalboush
Dental Caries, Endodontically Treated Teeth
Clinical Performance of Posterior Indirect Adhesive Restorations
Clinical performance of indirect adhesive restorations - onlays, overlays- luted with light-cured composite resin will be evaluated.
- Conditions
- Dental Caries, Endodontically Treated Teeth, Dental Restoration Failure of Marginal Integrity, Wear, Occlusal
- Trial name
- NCT04838483
- Testing
- Indirect adhesive restoration of posterior teeth
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Okan University
Dental Caries, Tooth Demineralization
Evaluation of Optical Coherence Tomography in Dentistry
Optical coherence tomography (OCT) is a medical diagnostic tool, providing non-invasive, non-radiative and high resolution imaging. OCT has been established since many years in ophthalmology.
- Trial name
- NCT03753256
- Testing
- Transbond XT, Protecto®CaF2Nano, Pro Seal®
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Heidelberg Medical Center
Dental Caries
The Anticariogenic Effect of Miswak (Silvadora Persica) and Grape Seed Extract
Prevention of dental caries has taken a great importance in the last decade. The use of herbal and natural products became mandatory to avoid the side effects of commercially available medications.
- Trial name
- NCT04136639
- Testing
- Miswak, Grape Seed Extract Mouthwash, fluoride
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
HIV Infections
Study of Viral Load Decay Rates in HIV Infected Participants Starting Treatment With Raltegravir (RAL) and Emtricitabine/Tenofovir Disoproxil Fumarate (TDF)
The HIV integrase inhibitor, raltegravir (RAL), which was recently approved by the FDA, has been shown in several trials to be highly effective.
- Trial name
- NCT00660972
- Testing
- Raltegravir, Emtricitabine/tenofovir disoproxil fumarate
- Where
- 15 sites in United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Dental Caries, Gingivitis
Oral Hygiene Intervention Pilot Study
The main goals of this pilot study are to develop a nursing home-customized oral hygiene protocol, intended to be delivered primarily by dental hygienists and primary care providers, and to identify potential obstacles and…
- Trial name
- NCT02668809
- Testing
- oral health assessment, Questionnaires, Clinical Exam
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Leonardo Marchini
Dental Pain, Dental Caries
Impact of Dental Pain on the Quality of Life
The aim of the present study was to evaluate the perceived impact of dental caries and dental pain on oral health-related quality of life (OHRQoL) among preschool children and their families.
- Trial name
- NCT02443207
- Volunteers
- 843 people, healthy volunteers welcome
- Sponsor
- Ana Flavia Granville-Garcia
Dental Caries, Gingivitis
Shifts in the Oral Biofilm of Patients With Known Oral Health Risk Factors
This study is observational only and is intended to evaluate changes in the makeup and function of bacteria naturally present in the mouth during treatment with braces to straighten teeth.
- Trial name
- NCT02885064
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Dental Caries in Children
Clinical Retention of Glass Ionomer Sealants Placed With and Without Rubber Dam: a Comparative Analysis
A comparative analysis of glass ionomer sealant placed on permanent molars with and without a rubber dam to assess the retention over a 2 year period.
- Trial name
- NCT03989687
- Testing
- Fuji Triage, isolation
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Irreversible Pulpitis (Toothache), Dental Caries (Diagnosis)
Evaluation of the Success Rate of Pulpotomy Versus to Root Canal Therapy in Management of Mature First Permanent Molars With Irreversible Pulpitis
The goal of This current study compare the clinical \& radiographic success rate between two different modalities conventional RCT and VPT using Bio-C-Repair as a pulp capping material to treat young patients with mature first…
- Trial name
- NCT07046533
- Testing
- (pulpotomy), root canal treatment
- Volunteers
- 60 people
- Sponsor
- Lamiaa Saeed Ahmed Elshiekh
Dental Caries
Remineralizing Efficacy of Grape Seed Extract in Management of White Spot Lesion in Post Orthodontic Treated Patients.
This clinical trial will be conducted to compare the efficacy of grape seed extract oil versus sodium fluoride mouth wash in the management of remineralization in adult patients with white spot lesion over six months.
- Trial name
- NCT04357093
- Testing
- Grape seed extract mouthwash, Sodium fluoride mouthwash
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Early Childhood Caries
Comparing Controlled Flow Delivery Dentapen® Technique to Traditional Syringes
This study compares the effect of the controlled flow delivery Dentapen® technique to traditional syringes on pain perception during dental procedures among a group of pediatric dental patients
- Trial name
- NCT05959642
- Testing
- dentapen, Traditional metal Syringes
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis, MEDİTERRANEAN DİET
Evaluation of Nutritional Habits, Oral Hygiene, Relationship Between Dental Caries and Periodontal Condition
The purpose of this observational study is to identify the dental and periodontal health issues, oral hygiene practices, and potential relationships between them by assessing the variables that may have an impact on them.The main…
- Trial name
- NCT06129357
- Testing
- 180 individuals who applied to the Periodontology Clinic were included in the study. Individuals were divided into 3 groups as healthy (n=60), gingivitis (n=60) and periodontitis (n=60).
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Necmettin Erbakan University
Irreversible Pulpitis, Caries,Dental
Evaluation of Antimicrobial, Post Operative Pain of Cinnamon Extract Versus Sodium Hypochlorite Irrigant Following Pulpectomy of Primary Teeth
The aim of the study is to evaluate effectiveness of cinnamon extract versus sodium hypochlorite as root canal irrigant for in pulpectomy of primary teeth in reduction of bacterial count .
- Trial name
- NCT05860712
- Testing
- Irrigation
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, White Spot Lesion
A Randomized Controlled Trial of Vitamin D Supplementation on Salivary Biomarkers and Cariogenic Oral Microbiome
The goal of this clinical trial is to compare the treatment effect of vitamin D supplementation and topical fluorides in the population having vitamin D deficiency and Initial Carious Lesions (ICL) on the progression of ICL in…
- Conditions
- Dental Caries, White Spot Lesion, Initial Caries, Incipient Enamel Caries
- Trial name
- Incipient (NCT06172764)
- Testing
- Vitamin D supplements along with behavioral modification, Topical fluoride application and Vitamin D supplements along with behavioral modification, Topical fluoride application along with behavioral modification
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Dental Caries
Effectiveness of Resin Sealants: Retrospective Cohort Study
This retrospective cohort study assessed sealant clinical success applied to pit and fissure by dental undergraduate students at Piracicaba Dental School - Brazil.
- Trial name
- NCT02649816
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Fernanda Miori Pascon
Dental Caries, Tooth Wear
DIMOH: New Digital Methods for Monitoring Oral Health. An in Vivo Assessment
The objectives of this study are i) to monitor the oral health of young people over a period of one year and ii) to assess the ability of a new intraoral scanner combining fluorescence with 3D imaging to detect and monitor…
- Trial name
- NCT04050306
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Decay, Dental
Effect of Natural Antibacterial Mouthwash on Taste, Salivary pH and Bacteria in High Caries Risk pt
Evaluate the effect of propolis extract mouthwash and pomegranate extract mouthwash on taste alteration, salivary pH and antibacterial activity against streptococcus mutans in high caries risk patients.
- Trial name
- NCT03623048
- Testing
- chlorhexidine, saline, Propolis extract
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Clinical and Radiographic Evaluation of Silver Diamine Fluoride Versus Light-Cured Silver Diamine Fluoride in Carious Primary Molars
This randomized clinical trial aims to evaluate and compare the clinical and radiographic performance of 38% silver diamine fluoride (SDF) with 38% silver diamine fluoride followed by light curing in children with carious primary…
- Trial name
- NCT07903155
- Testing
- Silver diamine Fluoride 38%, LED light curing
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
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