Clinical trials: Caries, Dental
Root Caries
Silver Diamine Fluoride Application on Root Caries Fillings
The goal of this clinical trial is to learn the influence of prior silver diamine fluoride (SDF) application on root caries fillings. The main questions to answer 1.
- Trial name
- NCT06514885
- Testing
- SDF solution application, Tonic water
- Where
- Hong Kong
- Volunteers
- 184 people
- Sponsor
- The University of Hong Kong
Tooth Loss, Dentin Caries
PMCF Study on The Performance and Safety of ON DENT® PMMA Discs/Blocks and Resin Products for Temporary Restorations
This prospective, single-center, interventional post-market clinical follow-up (PMCF) study aims to evaluate the clinical performance and safety of temporary crown and bridge restorations fabricated using CE-marked ON DENT™…
- Conditions
- Tooth Loss, Dentin Caries, Tooth Fractures
- Trial name
- NCT07632443
- Testing
- Temporary Fixed Prosthesis (Tempo-CAD Monocolor PMMA), Temporary Fixed Prosthesis (Tempo-CAD Monocolor SHT PMMA), Temporary Fixed Prosthesis (Tempo-CAD Multicolor SHT PMMA)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- On Dent Tibbi Malzeme Dis Protez Ith. ve Ihr. San. Ltd. Sti.
Dental Caries in Children
Validation of the Arabic Version of the Caries Questionnaire
Arabic is one of the most spoken languages in the world; however, the CARIES-QC questionnaire which evaluate the effect of oral diseases and disorders on children's oral health-related quality of life has not yet been validated…
- Trial name
- NCT04882852
- Where
- Egypt
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Primary Teeth
Carie Care, Chemomechanical Caries Removal Technique in Primary Teeth
Chemomechanical caries removal systems have emerged as a possible valuable alternative to conventional rotary caries removal techniques in pediatric patients.
- Trial name
- NCT05538559
- Testing
- Chemomechanical caries removal by Carie-Care, Mechanical caries removal by Atraumatic Restorative Technique
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Hams Hamed Abdelrahman
Caries Experience
Evaluation of Dental Caries Using Caries Assessment Spectrum and Treatment Need (CAST) Index, International Caries Detection and Assessment System (ICDAS) Index and World Health Organization (WHO) Index
This study goals is to compare the three indices in Egyptian children aged 4 to 6 years in caries detection and time needed for the assessments which will contribute to valuable data for pediatric oral health assessments both…
- Trial name
- CAST/ICDAS/WHO (NCT06858462)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cairo University
Class V Dental Caries
Assessment of Alkasite Restorative Material Versus Resin Modified Glass Ionomer in Class V Cavities: A Clinical Trial
This study will be conducted to evaluate the clinical assessment of an alkasite based resin composite restorative material compared to resin modified glass ionomer based restorative material in class V cavities of anterior teeth…
- Trial name
- NCT06673888
- Testing
- Resin modified glass ionomer, alkasite based restorative material
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Deep Caries, Indirect Pulp Capping
Pulp Capping in Primary Molars Using TheraCal (LC)
A randomized clinical trial that aims to evaluate clinical and radiographic success rates of indirect pulp capping and direct pulp capping in primary molars with reversible pulpitis using a light-cured tri-calcium silicate base…
- Conditions
- Deep Caries, Indirect Pulp Capping, Direct Pulp Capping, Reversible Pulpitis
- Trial name
- NCT05167123
- Testing
- Light cured tri-calcium silicate base material
- Where
- 3 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries, Fissure Sealants
Comparative Evaluation of Glass Ionomer and Resin-Based Fissure Sealants on Newly Erupted Permanent First Molars: A 24-Month Randomized Clinical Trial
This clinical study aims to compare the clinical performance of two different fissure sealant materials-glass ionomer and resin-based-when applied to newly erupted permanent first molars in children.
- Conditions
- Dental Caries, Fissure Sealants, Permanent Molars, Child
- Trial name
- FISSURE24 (NCT07115290)
- Testing
- Glass ionomer-based fissure sealant, Resin-based fissure sealant
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Gulcin Bulut
Dental Caries in Children
SDF Effectiveness on Arresting Caries in Children
Purpose: To assess the clinical effectiveness of silver diamine fluoride (SDF) to control asymptomatic cavitated carious lesions compared to conventional glass ionomer restoration in preschool children.
- Trial name
- NCT05872542
- Testing
- Silver Diamine Fluoride (SDF), Glass Ionomer Restoration (GI), Sodium fluoride varnish with nano-sliver particles (NaF-AgNP)
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Umm Al-Qura University
Dental Caries
ASSESSMENT OF SDF vs. GIC AND HALL TECHNIQUE
Early childhood caries (ECC) ,a global public health problem, highly prevalent and severe with life long implications is entirely preventable.
- Trial name
- NCT05117268
- Testing
- SDF Application for caries arrest, Glass ionomer restoration, Hall technique
- Where
- Pakistan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Dental Anxiety
Video Modelling and Dental Determinants on Dental Anxiety in Children
The goal of this clinical trial is to determine if video modelling reduces dental anxiety in children aged 8-12 years in Depok City.
- Trial name
- VMDDAC (NCT07365774)
- Testing
- "Let's Go to the Dentist!" Video Modelling, "Let's Brush Our Teeth!" General Dental Education Video
- Where
- 6 sites in Indonesia
- Volunteers
- 496 people
- Sponsor
- Wisnu Fadila
Caries,Dental
Nano-hydroxyapatite and Ozone - Effect on Approximal Initial Caries
Objectives: to assess the efficiency of three methods of enamel remineralization on initial approximal caries: 1. a nano-hydroxyapatite gel, 2. gaseous ozone therapy 3. combination of a nano-hydroxyapatite gel and ozone.
- Trial name
- NCT04147091
- Testing
- ApaCare & Repair
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Class V Dental Caries
Clinical Performance of Nanohybrid Resin Composite Lined With PRG Barrier Coat Compared to Resin Modified Glass Ionomer in Class V Carious Cavities Over 18 Months: Randomized Clinical Trial
Class V carious lesions will be restored using two different restorative materials either Resin modified glass ionomer or nanohybrid resin composite lined by PRG barrier coat.
- Trial name
- NCT05605457
- Testing
- PRG barrier coat + nanohybrid composite, resin modified glass ionomer
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Deep Caries
Treatment of Primary Molars With Deep Caries Using Silver Diamine Fluoride
Untreated dental caries is a worldwide pandemic (Edelstein, 2006). Due to limited financial resources, poor access to basic oral care, and the high cost of restorative treatment, children of low-income nations have their general…
- Trial name
- NCT03563534
- Testing
- Silver Diamine Fluoride, Glass Ionomer
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries in Children
Comparative Study Between Smart Bur II and Traditional Carbide Bur in Selective Removal of Caries in Permanent Molars
A more biological and conservative technique of caries removal has emerged with minimally invasive restorative dentistry's advent. As a result, Smart Burs II has become a self-limiting, sensitive tool for removing caries.
- Trial name
- NCT06187259
- Testing
- caries removal by carbide bur, caries removal by polymer bur II
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Dental Caries
Fissure Caries Inhibition Study With Solea CO2-9.3μm Short-pulsed Laser
The objective of this clinical study is to evaluate whether the use of the new CO2 - 9.3μm short-pulsed laser increases the caries resistance of occlusal pit and fissure surfaces in patients in addition to fluoride therapy.
- Trial name
- LaserFissure (NCT02357979)
- Testing
- Laser, Fluoride
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dental Caries in Children
Clinical Performance of Resin-modified Glass Ionomer and Composite Restorations in Permanent Teeth
The aim of this randomised controlled double-blinded, split mouth, single-center clinical trial was to evaluate the 18-month clinical performance of nano-filled resin-modified glass ionomer and sub-micron hybrid resin composite…
- Trial name
- NCT05583682
- Testing
- Dental restoration
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Hacinlioglu, Nadya Marie
Caries,Dental
Artificial Intellegence Rivals Digital Bitewing in Detect Secondary Caries
This study uses digital bitewing radiography as a standard for diagnosing proximal secondary caries. Patients will undergo imaging with a parallel technique and fixed settings to ensure high-quality, consistent images.
- Trial name
- NCT06667986
- Testing
- artificial intelligence models (YOLO and Mask-RCNN)
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Cairo University
Enamel Lesions, Dental Caries
Comparison of Different Methods of Enamel Preparation Before Pit and Fissure Sealants
This study concerns the prevention of dental caries by sealing pits and fissures of permanent molars with a photopolymerizable resin.
- Trial name
- NCT02594020
- Testing
- air abrasion, sono abrasion, dental bur
- Where
- 2 sites in France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Primary Dental Caries
Detection of Residual Caries on Class II Cavity Walls in Primary Teeth Following Atraumatic Restorative Treatment (ART)
The primary aim of this study is to compare the diagnostic agreement and effectiveness of three different methods-Fluorescence-Aided Caries Excavation (FACE), caries detection dye, and clinical observation-in detecting residual…
- Trial name
- NCT07250022
- Testing
- FACE + Caries Detection Dye, FACE + Visual-Tactile Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
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