Clinical trials: Caries, Dental
Tooth Decay
COMPARISON OF SECTIONAL MATRIX VERSUES CIRCUMFERENTIAL MATRIX FOR RECONSTRUCTION OF PROXIMAL CONTACT IN CLASS 2 RESTORATIONS
Class II caries affects proximal surfaces of premolars and maintain their anatomical proximal contact of tooth, is important to avoid food impaction in the interdental area for protection of periodontium and occurrence of…
- Trial name
- NCT05734027
- Testing
- Sectional matrix, Circumferential matrix
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Class II Dental Restorations
Clinical Evaluation of a Simplified-Shade Nano-Hybrid Composite With Full-Coverage Silane Coating and High-Performance Pulverized Fillers
The goal of this clinical trial is to evaluate simplified, shade, non-hybrid composite versus conventional multi Shade nano hybrid composite in class two restorations and reevaluate after one year follow up It's aim to answer…
- Trial name
- FSC-HPC-GC (NCT07334509)
- Testing
- Simplified Nano hybrid composite, Conventional, multi shade nano, hybrid composite
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Comparison Between Biodentine and Calcium Hydroxide in the Indirect Pulp Treatment on Primary Teeth
Objective: The study's main purpose is to evaluate and compare the clinical and radiographic outcomes of Biodentine and a light-activated calcium hydroxide based-liner (Ultra-Blend plus®) as indirect pulp treatment (IPT) liners…
- Trial name
- IPT (NCT02799927)
- Testing
- Indirect Pulp Treatment with Bioactive Dentin Substitute, Indirect Pulp treatment with Calcium hydroxide
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- José Arturo Garrocho Rangel
HIV-1 Infection
Short-term Disulfiram Administration to Accelerate the Decay of the HIV Reservoir in Antiretroviral-treated HIV Infected Individuals
The purpose of this study is to determine whether a two-week course of disulfiram will reduce the HIV-1 latent reservoir in patients on highly active antiretroviral therapy (HAART).
- Trial name
- NCT01286259
- Testing
- Disulfiram
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- University of California, San Francisco
Dental Caries, Child Behavior
Efficacy of Moderate Sedation for Dental Treatment of Young Children
There is lack of clinical trials on pediatric dental sedation. The purpose of this study is to test (using a randomized controlled trial design) the hypothesis that young children behavior during dental treatment improves with…
- Conditions
- Dental Caries, Child Behavior, Conscious Sedation Failure During Procedure
- Trial name
- NCT00902395
- Testing
- Midazolam, Protective stabilization, Midazolam, ketamine
- Where
- Brazil
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Caries,Dental
Clinical Performance of Injectable Composite Resins in Class I Cavities
Purpose of research: Evaluation and comparison of 24-month clinical performance of injectable and conventional resin composites in class I cavities.
- Trial name
- NCT06192667
- Testing
- GC Geanial Injectable (Tokyo,Japan), 3M Filtek Z250 Universal Restorative (Germany)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
High Caries Risk, Low Caries Risk
TAS1R1, TAS1R3, TLR2, TLR4, CA6 Gene Polymorphism on Dental Caries
The aim of this study is to examine the effects of TAS1R1, TAS1R3, TLR2, TLR4, CA6, gene polymorphism on caries risk in adults.
- Trial name
- NCT04066101
- Testing
- high caries risk, caries activity
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Dental Caries
In Situ Remineralisation Response of Different Artificial Caries-like Enamel Lesions to Home-care and Professional Fluoride Treatments
This study mainly compared the response of the artificial carious enamel lesions to remineralisation in situ. The tested in vitro demineralising protocols were: MC gel, PA gel, MHDP and Buffer solutions.
- Trial name
- NCT02637830
- Testing
- Application of fluoride varnish (22600 ppm F, Duraphat) at the begining of the study, Application of fluoride toothpaste (1500 ppm F, Crest) twice a day for 3 days of the study
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Caries
Healozone Study to Evaluate the Safety and Efficacy of the Use of Ozone for Management of Dental Caries
Caries means demineralization with the formation of cavities and pulp symptoms and necrosis as an end result. The acids in the mouth are mainly produced by oral bacteria like Streptococcus mutans from bacterial biofilms adhering…
- Trial name
- NCT00495495
- Testing
- Ozone treatment
- Where
- 3 sites in United States
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- Indiana University
Dental Caries
Waukesha Smiles: Dental Outreach to Low-income Waukesha Children
The Waukesha Smiles Project will compare approaches to improve oral health habits and increase access to basic dental care for low-income children in Waukesha, Wisconsin through a school-based outreach program of oral health…
- Trial name
- NCT00703001
- Testing
- Educational Intervention, Referral Intervention
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Dental Caries
Efficacy and Safety of Primary Teeth Anesthesia Using Nasal Spray in Children
68 healthy children from the Department of Pediatric Dentistry at Damascus University who require treatment for their primary maxillary second molars will be randomly assigned into one of two groups: experimental or control…
- Trial name
- NCT03140787
- Testing
- Nasal Spray of Lidocaine HCL, Infiltration injection of Lidocaine HCL
- Where
- Syria
- Volunteers
- 68 people
- Sponsor
- Damascus University
Overweight
Delivering Geospatial Intelligence to Health Care Providers
Physician counseling for physical activity, dental services, and academic support services such as tutoring could be improved through physician knowledge of local community resources and physician counseling directing patients to…
- Trial name
- CHICA GIS (NCT01567228)
- Testing
- CHICA GIS (enhanced electronic medical record)
- Where
- United States
- Volunteers
- 1,076 people
- Sponsor
- Indiana University
Caries Arrested
Selective Versus Stepwise Removal of Deep Carious Lesions in Permanent Teeth Using Different Medicaments
The study involved 54 adult patients between the ages of 18 and 50 years who had a posterior permanent tooth with a deep occlusal (Class I) carious lesion that extended to the inner third of the dentin (D3) and divided them into…
- Trial name
- NCT06585436
- Testing
- partial caries removal
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries
Use of Antibacterial Cement in Infected Dentin
Dental materials with antibacterial properties can prevent the harmful effects caused by oral cariogenic bacteria. This double-blind controlled clinical trial evaluated the performance of antibacterial cement for sealing infected…
- Trial name
- AC (NCT01449136)
- Testing
- Antibacterial cement
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Pernambuco
Class II Dental Caries
Influence of Lateral Pressure on Sectional Matrix
The aim of this study was evaluating the clinical effectiveness of the hand instrument in conjunction with sectional matrix when applying lateral forces at the contact area during curing to achieve large and tight proximal…
- Trial name
- NCT05423639
- Testing
- palodent, optracontact
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Kidney Disease
Oral and Dental Health Status in Patients Suffering From Chronic Kidney Disease
A large panel of oral and dental diseases exist in patients suffering from chronic kidney disease (CKD) in end-stage renal disease: it concerns teeth, peridontium, alveolar bone and saliva and it has been already described in the…
- Trial name
- NEPHRODENT (NCT02114281)
- Testing
- Care, Not care
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Bordeaux
Dental Caries in Children
Evaluation of the Antimicrobial Fiber Reinforced Composite Resin Space Maintainer Modified With Silver Nano Particles
Fiber reinforced composite resin space maintainer
- Trial name
- NCT05902975
- Testing
- Fiber reinforced composite resin space maintainer
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries
Oral Alkali Production and Caries Prevention in Children (Cross-sectional Component)
The fact that dental caries remains a major public health problem mandates that oral-health researchers explore new strategies for assessment of caries risk, as well as for caries prevention and management.
- Trial name
- NCT02368028
- Testing
- Oral Samples
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- University of Florida
Dental Restoration Failure of Marginal Integrity, Dental Caries
Longevity of Dental Fillings Utilizing 3D Printing
The aim of the present study is to compare the success of dental fillings prepared using 3D printing technique to those manufactured with the direct composite technique.
- Trial name
- NCT04630587
- Testing
- Indirect restorations
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Dental Plaque, Dental Caries
Family-based Counseling Models for Young Children
The purpose of this study is to compare the effects of two new family-based oral health promotion programs with the routine program in use earlier in Vantaa public dental service.
- Conditions
- Dental Plaque, Dental Caries, Behaviorial Habits
- Trial name
- NCT01854502
- Testing
- Oral hygiene and fluoride use, Diet and use of xylitol
- Where
- Finland
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- University of Turku
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