Clinical trials: Caries, Dental
Caries, Dental, Pulpitis
Indirect Pulp Capping With Resin Modified Glass Ionomer
In deep carious lesions, presenting risk of pulp exposition, a treatment option is the partial caries removal of carious tissue followed by provisional restoration, while this approach is called indirect pulp capping.
- Trial name
- NCT02494193
- Testing
- Partial caries removal, Provisional restoration - control, Provisional restoration - experimental
- Where
- Brazil
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Dental Caries
Arresting Active Dental Caries in Preschool Children by Topical Fluorides
This randomized clinical trial aims to compare the effectiveness of three topical fluoride application protocols, namely three applications of a 30% SDF solution at yearly or weekly interval and three applications of a 5% NaF…
- Trial name
- NCT02426619
- Testing
- SDF solution, NaF varnish
- Where
- China
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dental Caries
A Clinical Study to Evaluate Experimental Children's Toothpastes in an In-Situ Caries Model
An in situ model will be used to evaluate and compare enamel remineralization of human enamel specimens after single use of experimental children's toothpastes.
- Trial name
- NCT01607411
- Testing
- Fluoride
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Oral Findings in Children of Multiple and Single Births, Radiographic Evaluation of Oral Findings in Children of Multiple and Single Births
Clinical and Radiographic Evaluation of Oral Findings in Children of Multiple and Single Births
Clinical and radiographic evaluation of oral findings in children of multiple and single births
- Trial name
- NCT04697017
- Testing
- The contribution of genetics to dental caries, oral habits and occlusal traits in children of multiple births
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 690 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Dental Caries
Reminerlization Potential of GSE Gel versusCPP-ACP in Carious White Spot Lesions in Post Orthodontic Patients
Assess the effectiveness of applying grape seed extract (GSE) gel versus casein phosphopeptide-amorphous calcium phosphate (MI) paste on remineralization of white spot lesion (WSLs) in post orthodontic patients.
- Trial name
- NCT03966378
- Testing
- Grape seeds extract, Casein-phosphopeptide/amorphous-calcium phosphate
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries in Children
Pharmacokinetics of Advantage Arrest in Healthy Children 13-Months to 13-Years of Age
The purpose of this study is to further characterize basic pharmacokinetic (PK) parameters in healthy children to contribute to evidence for the safety of silver diamine fluoride (SDF; Advantage Arrest).
- Trial name
- NCT05670743
- Testing
- 38% silver diamine fluoride
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Advantage Silver Dental Arrest, LLC
Pediatric Dental General Anesthesia, Restoration
Clinical Performance and Failure Rates of Restorations Following Pediatric Dental Rehabilitation Under General Anesthesia
Full-mouth dental rehabilitation under general anesthesia (GA) is frequently required for young children with extensive dental caries, behavioral challenges, or special healthcare needs.
- Conditions
- Pediatric Dental General Anesthesia, Restoration, Clinical Performance, Full Mouth Rehabilitation
- Trial name
- NCT07827833
- Testing
- Routine Restorative Materials and Treatment Methods
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Tanta University
Dental Caries
DPBRN Development of a Patient Based Provider Intervention for Early Caries Management
This study focused on improving the quality of dental care by fostering movement of the latest scientific advances into daily clinical practice.
- Trial name
- NCT01309958
- Where
- 7 sites in United States, Denmark
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
Dental Caries, Secondary Dental Caries
Clinical Criteria for the Evaluation of Caries Lesions Around Restorations in Primary Teeth (CARDEC-03)
There is still great divergence in the aspects related to caries lesions around restorations. The methods and the systems used for the detection of secondary caries lesions have presented low validity.
- Trial name
- CARDEC-03 (NCT03520309)
- Testing
- Dental treatment
- Where
- Brazil
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Caries (Diagnosis), Dental Plaque (Diagnosis)
Assessment of Dental Pathologies Using Digital Tools
Digital technology is playing an increasingly important role in dentistry, because of its ability to support the practitioner and increase work efficiency.
- Conditions
- Dental Caries (Diagnosis), Dental Plaque (Diagnosis), Periodontitis
- Trial name
- RESTODATA-NUM (NCT07205588)
- Where
- 22 sites in France, Reunion
- Volunteers
- 350 people
- Sponsor
- Recherche Clinique en Odontologie (ReCOL)
Caries,Dental
Long-term Effects of a Lay Health Advisor Intervention on Immigrant Children's Caries
The aim of this study was to evaluate the long-term effectiveness of a lay health advisor (LHA) intervention on immigrant children's caries and preventive behaviors.This randomized controlled trial included mother-child pairs in…
- Trial name
- NCT04562675
- Testing
- LHA intervention, brochure-only
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Dental Caries
Masticatory Performance in Mixed Dentition Children Before and After Dental Treatment
This prospective clinical study aimed to evaluate the effects of dental treatment on masticatory performance and food preferences in children during the mixed dentition period.
- Trial name
- NCT07271901
- Testing
- Dental Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- TC Erciyes University
Dental Caries
Preventive Regimens With Herbal and Fluoride Toothpaste on Remineralization in High Caries Patients With Initial Lesions
This study will be conducted to assess the effect of different preventive regimens using herbal toothpaste versus fluoride toothpaste on the management of remineralization and caries risk in high caries risk patients.
- Trial name
- NCT04446390
- Testing
- Himalaya complete care toothpaste, colgate cavity protection
- Where
- 2 sites in Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Class I Dental Caries
Comparison of Postoperative Sensitivity in Posterior Teeth Using Conventional and Bulkfill Composites
The purpose of this study is to compare the onset and severity of pain and postoperative sensitivity in patients after using conventional nanohybrid and bulkfill composites Null Hypothesis: There is no significant difference in…
- Trial name
- NCT06852586
- Testing
- conventional nanohybrid composites, Bulk fill composites
- Where
- Pakistan
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- 28 Military Dental Centre Lahore
Preterm Birth, Periodontal Disease
Saving Lives at Birth: Primary Prevention of Periodontal Disease in Relation to Preterm Birth in Malawi
The hypothesis of the investigators' project is that comprehensive primary preterm birth prevention, inclusive of maternal oral health with xylitol chewing gum (the intervention), will reduce the rate of periodontal disease and…
- Conditions
- Preterm Birth, Periodontal Disease, Caries, Dental
- Trial name
- PPaX (NCT02333227)
- Testing
- Xylitol gum
- Where
- United States
- Volunteers
- 10,069 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Carious Lesion
Efficacy of Nanoparticle-incorporated Bonding Agent on Post-restorative Sensitivity
Type of study: Randomized Clinical trial To compare post-restorative sensitivity between titania nanoparticle reinforced bonding agent and bonding agent without nanoparticles in posterior composite restorations.
- Trial name
- NCT05744648
- Testing
- Composite resin restoration using Titania nanoparticle reinforced bonding agent, Composite resin restoration without Titania nanoparticle incorporated bonding agent
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Dental Caries
Silver Diamine Fluoride Pilot Study (SDF)
This pilot trial is randomized, double-blind, and placebo-controlled trial with two parallel arms: an intervention group using silver diamine fluoride (SDF) and a placebo group (control).
- Trial name
- SDF (NCT02591147)
- Testing
- Silver Diamine Fluoride 38%
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Justine Kolker
Caries, Dental
Treatment of Immature Permanent Teeth With Three Different Pulp Capping Materials With Partial Pulpotomy
The aim of this randomized controlled trial is to compare partial pulpotomy treatments with Biodentine®, calcium hydroxide (CH) and Mineral Trioxide Aggregate (MTA) in cariously exposed asymptomatic young permanent teeth…
- Trial name
- NCT03426046
- Testing
- Partial Pulpotomy, Pulp Capping Agents
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Didem Sakaryali
Dental Caries
CAMBRA - PBRN Caries Management By Risk Assessment In A Practice-Based Research Network
The goal of this project is to create a Practice Based Research Network with 30 researcher dentists calibrated on the administration of a caries risk assessment and the treatment modalities recommended based on the caries risk…
- Trial name
- CAMBRA-PBRN (NCT01176396)
- Testing
- Caries prevention active intervention, control treatment
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Artificial Intelligence, Education
Impact of Training Dental Students for an AI-Based Platform
The emergence of artificial intelligence (AI) and specifically deep learning (DL) have shown great potentials in finding radiographic features and treatment planning in the field of cariology and endodontics .
- Trial name
- NCT05912361
- Testing
- receiving a one hour theoretical and hands on training session before using an AI-based platform
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
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