Clinical trials: Caries, Dental
Dental Caries
Clinical Performance of Incremental and Bulk Fill Composites in Class II Restorations
This study will examine the clinical performance of Class II restorations over a three year period with 3 composite resins - a conventional composite resin, a flowable composite resin and a bulk placed and cured composite resin.
- Trial name
- NCT02889835
- Testing
- Supreme Universal Restorative, Supreme Flowable Restorative, Bulk Fill Flowable Restorative
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Dental Caries, Gingivitis
Effect of a 2-week Sugar Stress on Bacterial Profiles in Whole Saliva
Dental caries is a non-communicable biofilm-mediated disease affecting both crown and exposed root surfaces in the primary and permanent dentitions.
- Trial name
- NCT04199897
- Testing
- Succrose rinsing, Probiotic lozenges, xylitol rinsing
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Caries
Traditional vs. Minimally Invasive Decay Treatments in Primary Molars: An 18-month Split-mouth Randomized Study
The goal of this clinical trial is to compare the 18-month clinical success rates of three caries management approaches in primary molars of 60 healthy children aged 4-8 years attending the Department of Pediatric Dentistry at…
- Trial name
- MiCRO-PM (NCT07447583)
- Testing
- Hall Technique, Silver diamine Fluoride 38%, Compomer Restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Dental Caries in Children
Staining Potential and Caries Arresting Effect of Silver Diamine Fluoride⁄Potassium Iodide and Silver Diamine Fluoride
the main objective of this study is to evaluate staining potential and Caries Arresting Effect of silver diamine fluoride⁄potassium Iodide and silver diamine fluoride in carious anterior primary teeth
- Trial name
- NCT04196829
- Testing
- silver diamine fluoride ⁄ potassium Iodide, Silver Diamine Fluoride
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries in Children
Evaluation of New Different Herbal Mouthwashes Against Caries Forming Bacteria, RCT
The goal of this randomized controlled trial is to compare three different types of mouthwash, Moringa, Star anis, and Indian Costus 90 children participated in this study divided into 3 groups according to the type of mouthwash…
- Trial name
- NCT05623605
- Testing
- Moringa mouthwash, star anise mouthwash, Indian costus mouth wash
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Nahda University
Dental Caries
Diammine Silver Fluoride in Arresting Enamel Caries Lesions on Babies' Occlusal Surfaces
This study aims to verify the actual possibility of using silver diammine fluoride (SDF) in arresting enamel caries lesions on occlusal surfaces of primary molars in babies.
- Trial name
- NCT02789202
- Testing
- Silver diamine fluoride, Fluoride Varnish
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Caries
Clinical Performance of a Glass-ionomer Restorative System: A 6-year Evaluation
The aim of this clinical trial was to compare the clinical performances of a glass ionomer restorative system with a micro hybrid resin based composite in class I and class II cavities.
- Trial name
- NCT02888912
- Testing
- EQUIA, Gradia Direct Posterior
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries
the NMFACT Caries Index
the NMFACT is a new caries index to overcome the drawbacks of DMF cries index the ''N'' is for non carious lesion, the ''M''for missed teeth,the ''F''for filled teeth,the''C''for carious teeth,the ''A''for alignment and the…
- Trial name
- NCT04330794
- Testing
- NMFACT, DMF index
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
the Effect of Prenatal Vitamins on the Tooth Structure
the effect of mother prenatal care on the teeth of the newborn children, if it affect the tooth structure or not
- Trial name
- NCT03598972
- Testing
- intervention
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries in Children
The Pharmacokinetics of Silver Diamine Fluoride (SDF) in Healthy Children
This study focus on the pharmacokinetic characteristic of silver diamine fluoride (SDF) in healthy children. All of the children received treatment for the decayed teeth in the same way.
- Trial name
- SDF (NCT04766775)
- Testing
- Silver Diamine Fluoride
- Where
- Malaysia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Dental Caries, Oral Health
Effect of Probiotics Containing Yogurts on the Composition of Biofilms in Patients Under Orthodontic Treatment
Aim: To assess in vivo if the intake of yogurt containing Bifidobacterium animalis ssp. lactis DN- 1173010 probiotic for a period of 2 weeks affects the salivary levels or biofilms of mutans streptococci and the lactobacilli of…
- Trial name
- NCT01657539
- Testing
- Yogurt containing probiotics
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Class I Dental Caries
Flowable Resin Composite: Two-Year Clinical Performance in Class I Restorations
Evaluating Two-year clinical performance of class I restored with four different flowable resin composite restorations.
- Trial name
- NCT07330193
- Testing
- Restoration with CFC, Restoration with HFFC, Restoration with SARC
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Mansoura University
Dental Caries, Teeth Loss
The Effect of Bitewing Radiography on Outcomes and Costs of Treating Caries in Permanent Teeth
Dentists commonly use bitewing radiographs (dental X-rays) together with a visual-tactile (clinical) examination to detect cavities between the back teeth.
- Conditions
- Dental Caries, Teeth Loss, Necrosis of Pulp, Irreversible Pulpitis
- Trial name
- BROCC (NCT07882693)
- Testing
- Visual-tactile caries examination, Visual-tactile caries examination and bilateral bitewing radiography
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jukka Leinonen
Dental Caries
Comparative Study of Experimental Dental Adhesive With and Without Phosphoric Acid Pretreatment
The intent of this study is to evaluate the clinical performance of an experimental dental bonding agent for use with dental restorative composites with and without pretreatment of the tooth dentin and enamel using phosphoric…
- Trial name
- NCT02071953
- Testing
- Experimental adhesive w/out phosphoric acid in post. rest., Experimental adhesive with phosphoric acid in post. rest.
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Dentsply International
Cavity, Dental
Clinical Performance of Bulk-fill Restorations in Class II Cavities
Direct composite resin restorations are considered an essential treatment option in the dental clinic because of increasing the demands for esthetics.
- Trial name
- NCT06461364
- Testing
- Assessment of cuspal deflection of bulk-fill restorations
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Egymedicalpedia
Dental Caries
Microbiome Changes After Laser and Chlorhexidine Disinfection in Caries Removal
The aim of this study was to investigate the effects of cavity disinfection with laser and chlorhexidine on the microbiome in cavities prepared using different caries removal methods.
- Trial name
- NCT06765330
- Testing
- CHX disinfection, Laser Disinfection, Tungsten carbide bur
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Mersin University
Dental Caries Tooth Demineralization, Post-Orthodontic Esthetic Defects
Evaluation of Self-assembling Peptides Versus Amorphous Calcium Phosphate in the Treatment of White Spot Lesions
This clinical trial aims to compare the effectiveness of two remineralizing treatments for white spot lesions (WSLs) on the enamel surfaces of the front teeth.
- Trial name
- NCT07146464
- Testing
- Self-Assembling Peptide P11-4 Self-Assembling Peptide P11-4 is a biomimetic material applied topically to white spot lesions on the enamel. It diffuses into the lesion body and forms a three-dimension
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Ain Shams University
Dental Caries
6-year Clinical Evaluation of Glass Ionomer Cements (GIS) With Resin Coating on Posterior Teeth
The aim of this study was to evaluate the long-term clinical performance of two highly viscous encapsulated GICs (EquiaFil and Riva SC) covered with two different coatings (Equia Coat and Fuji Varnish) over 6-year using modified…
- Trial name
- GIS (NCT02616198)
- Testing
- EquiaFil G-coat, EquiaFil Fuji Varnish, Riva SC G-coat
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ege University
Pulpitis, Caries; Dentin
The Effect of Cryotherapy on the Outcome of Pulpotomy and Root Canal Treatment
The goal of this randomized clinical trial is to compare the outcome of total amputation and root canal treatment with or without cryotherapy in terms of postoperative pain, quality of life, and treatment success for the…
- Conditions
- Pulpitis, Caries; Dentin, Pain, Postoperative
- Trial name
- NCT06183021
- Testing
- Vital pulp cryotherapy, Intracanal cryotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people
- Sponsor
- Ondokuz Mayıs University
Dental Hypersensitivity
Association of Two Desensitizing Protocols to Control Dentinal Hypersensitivity in Non-carious Lesions
This randomized, double-blind clinical trial evaluated the effect of photobimodulation associated with 8% strontium acetate in the treatment of dentin hypersensitivity in non-carious lesions and analyzed the risk factors with the…
- Trial name
- NCT04642001
- Testing
- Photon Laser III-DMC (without radiation emission) + My First- Colgate, Photon Laser III-DMC (without radiation emission) + Sensodyne® Rapid Relief / GSK, Photon Laser III-DMC (with irradiation emission) + My First- Colgate
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
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