Clinical trials: Caries, Dental
Dental Caries
Effects of Nystatin Suspension Oral Application on Oral Microbial Community
The purpose of this study is to examine the effect of a prescription mouth rinse (Nystatin),an FDA approved drug, on the different types of bacteria in the mouth.
- Trial name
- NCT04550546
- Testing
- Nystatin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Rochester
Dental Caries, Infectious Diseases
Bifidobacterium Lactis BB12 and Xylitol Delivered With a Novel Slow-release Pacifier
Aims: 1. To develop a food supplement containing a health-promoting probiotic bacteria (B. lactis BB12) and xylitol to be administered with a novel soft, possibly occlusion-friendly pacifier. 2.
- Trial name
- NCT00638677
- Testing
- Sorbitol, Xylitol + BB12, Xylitol
- Where
- Finland
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Turku
Deglutition Disorders, Dysphagia
Development of a Web-Based Course to Maintain Skills in Nurses Trained to Screen for Dysphagia
This research aims to facilitate the successful implementation of the new Heart and Stroke Foundation of Ontario dysphagia screening model for acute stroke patients.
- Conditions
- Deglutition Disorders, Dysphagia, Stroke
- Trial name
- NCT00570557
- Testing
- TOR-BSST© Refresher Training
- Where
- 5 sites in United States, Canada
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Caries, Dental, Risk Reduction
Using a Mouthwash Containing Propolis, Clove Oil and Chlorhexidine to Improve the Caries Risk of High Risk Patients
This study is conducted to determine if using a mouthwash containing propolis, clove oil and chlorhexidine will improve the caries risk of high risk patients in comparison to using a mouthwash containing chlorhexidine only.
- Trial name
- NCT03553628
- Testing
- Chlorhexidine, Propolis and Clove Oil mouthwash, Chlorhexidine mouthwash
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Moataz Gamal Ali Abdul-Maksoud Konsouh
Dental Caries Class v
Evaluation of the Marginal Integrity of Recent Bulk Fill Flowable Composite vs Glass Ionomer for Carious Cervical Restorations: RCCT
The study will be conducted to assess the marginal integrity of different types of restorations (ketac ™ N100 - ketac™ Universal and bulk fill flowable composite) in class v restoration using USPHS criteria.
- Trial name
- NCT04053530
- Testing
- restorative materials
- Where
- 2 sites in Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Dental Caries Class II
Clinical Performance of Novel Alkasite Restorative Material "Cention Forte" in Class II Restorations
Background \& Rationale: Self-adhesive materials eliminate the need for adhesive protocols, offering advantages for direct restorations. The bulk-fill technique simplifies application by allowing a single-layer restoration.
- Trial name
- NCT06833528
- Testing
- tooth restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Body Mass Index, Dental Caries
The Relationship Between Body Mass Index, Dental Eruption and Dental Caries Prevalence in School Children
The aim of the current study will be to explore the relationship between body mass index, dental eruption and dental caries prevalence in school Children.
- Conditions
- Body Mass Index, Dental Caries, Eruption
- Trial name
- NCT05902611
- Testing
- BMI determination, Eruption Time Assessment, Caries Assessment
- Where
- Egypt
- Volunteers
- 1,224 people
- Sponsor
- Al-Azhar University
Caries; Initial
Evaluation of Remineralization Potential of Self Assembling Peptide Combined With Fluoride
Self-assembling peptide (P11-4) exhibited an outstanding ability for biomimetic re-mineralization of incipient enamel carious lesions.
- Trial name
- NCT05094492
- Testing
- Curodont Repair Fluoride Plus, Bifluorid 10 fluoride varnish
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Cairo University
Dental Caries, Tooth Decay
Resin Polymer (NuSmile BioFlx) Compared to Stainless Steel Crowns (3M ESPE) for Restoration of Primary Molar Teeth
The purpose of this research study is to test the effectiveness of two different crowns/caps on teeth for restoration of primary molar teeth. The two different materials of crowns are resin polymer and stainless steel crowns.
- Trial name
- NCT06354634
- Testing
- Resin polymer (NuSmile Bioflx) crown, Stainless steel crown
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Virginia Commonwealth University
Dental Caries, Secondary Dental Caries
Influence of the Number of Layers of a One Bottle Adhesive on the Longevity of Composite Restorations in Primary Molars
The aim of this study is to determinate the influence of an alternative adhesive application protocol (i.e. consecutive application of an extra adhesive layer)on restoration longevity in primary molars.
- Trial name
- NCT01680289
- Testing
- Three adhesive coats, Two adhesive coats
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Dental Caries in Children, Dental Caries Class II
Treatment of Interproximal Cavities on Primary Molar Teeth With Silver Diamine Fluoride
This study investigates whether 1) Silver diamine fluoride (SDF) application using Super Floss can arrest and/or reverse initial interproximal caries on primary molars and 2) whether SDF applied with Super Floss is more effective…
- Conditions
- Dental Caries in Children, Dental Caries Class II, Dental Caries
- Trial name
- NCT03770286
- Testing
- 5% Fluoride Varnish, 38% Silver diamine fluoride, Super Floss
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Dental Caries in Children
Pandemic-adapted Caries Care Multicentre Single-group Interventional Study
The current understanding of dental caries has not been completely transferred into the clinical practice to control caries lesion progression (severity / activity) and the individual risk of caries.
- Trial name
- NCT04666597
- Testing
- Modified CariesCare International management
- Where
- 21 sites in United States, Argentina and 11 more
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- Universidad El Bosque, Bogotá
Dental Caries in Children
Prevention of Recurrent Caries With Lactobacilli PRECAL
The aim of this study was to compare the effect of drops containing probiotic bacteria (Lactobacillus reuteri 17938, Lactobacillus reuteri PTA 5289, Biogaia AB, Sweden) on the incidence of dental caries with placebo drops in…
- Trial name
- NCT04929340
- Testing
- Probiotic bacteria
- Where
- 3 sites in Sweden
- Volunteers
- 70 people
- Sponsor
- Umeå University
Dental Caries
Clinical Performance of Glass Ionomer Versus Resin Composite Restorations
The aim of this randomised-controlled, single-blind, split-mouth, and single-centre clinical trial was to evaluate the 2-year clinical performances of a high-viscosity glass ionomer and nanohybrid composite resin in occlusal…
- Trial name
- NCT04488380
- Testing
- dental restoration
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
DME, Dental Caries
The Effect of Bulk Filling Flowable Composite on Caries Recurrence in Deep Marginal Elevation: A Randomized Clinical Trial
Deep marginal elevation usinge a bioactive dental material in deep subgingival Class II restorations, S-PRG filler-containing materials offer significant benefits due to their bioactive properties, Their ability to release…
- Conditions
- DME, Dental Caries, Dental, Deep Margin Elevation
- Trial name
- NCT06900868
- Testing
- Assigned Interventions
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Dental Caries
Effect of Probiotic Drink on Number of Salivary Mutans Streptococci in School Going Children
This study was conducted to assess the effects of commercially available probiotic drink on the number of salivary mutans streptococci in school going children, aged 12-14 years in Bangalore city in India
- Trial name
- NCT01943123
- Testing
- probiotic drink
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Oxford Dental College, Hospital and Research Center, Bangalore, India
Dental Caries Class II
Retrospective Evaluation of Posterior Direct Restorations
This retrospective study aims to evaluate the clinical performance of posterior multi-surface Class II amalgam (AM) and resin composite (RC) restorations placed by dental students over a five-year period.
- Trial name
- NCT04827823
- Testing
- Retrospective evaluation of amalgam and composite restorations
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Dental Caries on Pit and Fissure Surface
Using ICDAS II and KaVo DIAGNOdent Pen Detecting Tooth Pit and Fissure Level Incipent Caries Progression
The study was to monitor effectiveness of glass ionomer sealant and resin-based sealant in ICDAS, and to evaluat the correlation between ICDAS and DIAGNOdent over 24 months.
- Trial name
- NCT03077035
- Testing
- glass ionomer sealants, resin-based sealant
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sheng-Chao Wang
Dental Caries, Knowledge
Implementation of Oral Health Educational Program on Orphan Children
Oral diseases are most prevalent among children. Orphans children are one of the most vulnerable groups to diseases especially oral diseases.
- Conditions
- Dental Caries, Knowledge, Practice
- Trial name
- NCT06428474
- Testing
- Health education
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Pharos University in Alexandria
Dental Caries, Hydroxyapatite
Study of People's Profile Living in France Who Could be Interested in the Use of a Nanohydroxyapatite Toothpaste
Nano-hydroxyapatite is an interesting candidate to be a substitute for fluor in toothpastes or a complement to fluorides in order to prevent caries.
- Trial name
- NCT05234060
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
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