Clinical trials: Caries, Dental
Dental Caries
Prevention of Enamel Demineralization by Use of K18-smooth Surface Sealant
This study will evaluate effectiveness of a urethane dimethacrylate (UDMA)-quaternary ammonium methacrylate (K18) resin (UDMA-K18) smooth surface sealant to prevent biofilm attachment to tooth surfaces thereby eliminating the…
- Trial name
- K18 (NCT03306433)
- Testing
- UDMA-K18 smooth surface sealant
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Dental Caries, Dental Atraumatic Restorative Treatment
Oral Health and Its Relation to Development and Well-being of Schoolchildren Before and After Restorative Treatments
The present study aims evaluate the oral health conditions of schoolchildren and its relation to growth, development and well-being.
- Conditions
- Dental Caries, Dental Atraumatic Restorative Treatment, Oral Health
- Trial name
- NCT02754466
- Testing
- Subjective vs objective criteria in selective excavation, Glass-ionomer vs Bulk fill composites in the ART approach
- Where
- Brazil
- Volunteers
- 270 people
- Sponsor
- University of Brasilia
Dental Caries
SEALANT-DK: Longevity and Efficacy of 6 Resin Sealants Used for Sealing Permanent Teeth in Children and Adolescents
Background: Occlusal caries is the main reason for restorative therapy in the young permanent dentition, but restorations have limited survival time and may also weaken the tooth.
- Trial name
- SEALANT-DK (NCT02561689)
- Testing
- Fissure sealing
- Where
- Denmark
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Oral Health, Parkinson Disease
Preliminary Study of the Quality of the Oral Flora in Parkinson's Patients
This is a prospective interventional clinical study whose main objective is to determine the impact of oral hygiene guidance on the oral health status of patients with Parkinson disease
- Trial name
- PARKIDENT (NCT03827551)
- Testing
- Delivery of oral hygiene advices
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Bordeaux
Dental Caries
EFFICACY OF MORUS ALBA FRUIT EXTRACTS AND CHLORHEXIDINE ON SALIVARY STREPTOCOCCUS MUTANS AND pH LEVELS
Dental caries is highly prevalent across the globe including Pakistan and is associated with tooth loss, malocclusion and temporomandibular joint problems and sometimes may cause life threatening infections.
- Trial name
- NCT05052775
- Testing
- Chlorhexidine Mouthwash, Morus Alba 20%, Morus Alba 30%
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Ziauddin University
Dental Caries
Antibacterial Effect of Nano Silver Fluoride vs Chlorhexidine on Occlusal Carious Molars Treated With Partial Caries Removal Technique
The teeth of the patients that meet inclusion criteria will be anesthetized, isolated with a rubber dam. Cavity opened using conventional high-speed rotary instruments.
- Trial name
- NCT03186261
- Testing
- Nano silver fluoride solution, Cavity Cleanser
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries in Children
Staining Potential and Caries Arresting Effect of Silver Diamine Fluoride⁄Potassium Iodide and Silver Diamine Fluoride
the main objective of this study is to evaluate staining potential and Caries Arresting Effect of silver diamine fluoride⁄potassium Iodide and silver diamine fluoride in carious anterior primary teeth
- Trial name
- NCT04196829
- Testing
- silver diamine fluoride ⁄ potassium Iodide, Silver Diamine Fluoride
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cairo University
Polycystic Ovary Syndrome, Dental Caries
Oxidative Stress in Polycystic Ovary Syndrome With Periodontal Disease and Dental Caries Lesions
This study evaluates the oxidative stress parameters in females with polycystic ovary syndrome (PCOS) and clinically healthy. Because of the fact that both oral disease included periodontitis and dental caries, and metabolic…
- Trial name
- NCT03594968
- Testing
- polycystic ovary syndrome
- Where
- Turkey (Türkiye)
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Dental Caries
Evaluation of Ion Releasing Hybrid Restorative Material
Esthetic and mechanical evaluation of calcium and phosphate releasing hybrid restorative material and fluoride releasing hybrid restorative material versus the conventional nanofilled resin composite in proximal carious lesions…
- Trial name
- NCT04854655
- Testing
- Conventional resin composite, Activa Presto, Giomer
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Dental Pulp Exposure
Stepwise and One Step Techniques In Deep Dentin Lesion
This double blind, randomized, controlled clinical trial aimed to observe the success of stepwise (SW) and one step (OneS) excavation techniques in the management of deep dentin caries.
- Trial name
- NCT04351048
- Testing
- Stepwise Excavation, One Step Excavation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TIJEN PAMIR
Dental Caries Class II, Dental Caries in Children
Arrest of Proximal Caries Using Orthodontic Bands and Glass Ionomer Cement
The purpose of this study is to evaluate the efficacy of using orthodontic bands with glass ionomer cement to arrest or reverse interproximal lesions as a preventive treatment compared to monitoring and oral hygiene.
- Conditions
- Dental Caries Class II, Dental Caries in Children, Dental Caries on Smooth Surface Limited to Enamel
- Trial name
- NCT04538963
- Testing
- Orthodontic Band affixed with Glass Ionomer Cement
- Where
- 2 sites in United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Decayed Teeth
3D Printed Donor Tooth Replica in Autotransplantation of Teeth
3D printed replicas of the donor tooth can reduce extraoral time during the autotransplantation of teeth, which can reduce dehydration and manipulation of periodontal tissue of the donor tooth, thus possibly increasing the…
- Trial name
- NCT04933409
- Testing
- 3D printed replica of the donor tooth, Conventional Autotransplantation of tooth
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- College of Medical Sciences Teaching Hospital. Nepal
Class I Dental Caries
Clinical Performance and Wear Resistance of Two Nano Ceramic Resin Composite in Class I Cavities
in patients with Class I Cavities, will the use of Zenit Nano Ceramic Composite restorations have similar clinical performance to conventional Ceram-X Nano Ceramic Composite restorations, evaluation of restorations will be done…
- Trial name
- NCT04738604
- Testing
- Ceram•X (Dentsply De Trey GmbH, Konstanz, Germany, Zenit Nano Ceramic Composite (PRESIDENT DENTAL, GmbH, Munich, Germany)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Proximal Dental Caries
Evaluation of Reliability of the Near-infrared Imaging System (VistaCam iX Proxi) in Comparison With Digital Radiographic Findings and ICDAS-II in Detection of Approximal Carious Lesions.
The aim of this study is to evaluate the Clinical performance of the near-infrared imaging system VistaCam iX Proxi in comparison with digital radiographic findings and ICDAS-II in detection of approximal carious lesions.
- Trial name
- NCT03923192
- Testing
- Vistacam, Bitewing radiograph
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oral Disease, Dental Caries
Implementing a Participatory, Multi-level Intervention to Improve Asian American Health Study
This feasibility and acceptability study will be conducted at 3 community outreach centers serving an urban, low-income Chinese population.
- Trial name
- NCT03438045
- Testing
- Partnered intervention
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- NYU College of Dentistry
Dental Caries (Disorder)
Color Match Assessment of a Single Shade Structurally Colored Universal Resin Composite
Matching the color of resin composite utilized in anterior teeth is believed to be one of the most challenging tasks a dentist has to face in daily practice.
- Trial name
- NCT04960852
- Testing
- a single shade structurally colored universal resin composite
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- National Research Centre, Egypt
Dental Caries in Children
Experimental Research on Deep Carious Lesion Treatment of Molars
Maintaining dental pulp vitality is crucial for tooth preservation and functionality. Untreated dental caries may lead to pulp necrosis and infection, affecting children's growth and well-being.
- Trial name
- VITAPULP (NCT03626740)
- Testing
- TheraCal, MTA
- Where
- Romania
- Volunteers
- 40 people
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Unsatisfactory Restoration of Tooth, Carious Teeth
Biological and Esthetic Evaluation of Ceramic Onlay With Different Preparation Designs
Aim of study: is to asses biological and esthetical success of ceramic onlay restorations while preparing the teeth using shoulder finish line preparation versus butt joint with bevel preparation.
- Trial name
- NCT04438642
- Testing
- shoulder finishline, butt joint with bevel
- Where
- Egypt
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Ahmed Adel Mahmoud Gadallah
Dental Caries
Clinical Performance of Posterior Glass Ionomer Restorations in Adolescents (KETAC)
The purpose of this study is to determine whether two tooth-colored glass ionomer materials are effective for load-bearing dental fillings.
- Trial name
- NCT02705729
- Testing
- Ketac Universal, Ketac Molar Quick
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Obesity, Type 2 Diabetes
The Influence of Simple, Low-Cost Chemistry Intervention Videos: A Randomized Trial of Children's Preferences for Sugar-Sweetened Beverages
Sugar-sweetened beverage (SSB) consumption is associated with the development of obesity, type 2 diabetes, and dental caries. The current study attempts to explore whether an educational, science-based intervention is able to…
- Conditions
- Obesity, Type 2 Diabetes, Dental Caries
- Trial name
- NCT04971317
- Testing
- Sugar-Sweetened Beverage (SSB) Video, Water Video, Control
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health