Clinical trials: Caries, Dental
Dental Caries
Is Biodentine, as Successful as, Mineral Trioxide Aggregate
: A split-mouth controlled clinical trial was carried out on 21 healthy, three to seven years old children, with 42 pairs (84 molars) of contralateral mandibular primary molars indicated for pulpotomy.
- Trial name
- NCT03686475
- Testing
- Biodentine, MTA pulpotomy
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries,Dental
Artificial Intelligence (AI) for Proximal Caries Detection and Its Impact on Treatment Threshold
The purpose of this study is to assess the impact of artificial intelligence on proximal caries detection and subsequent treatment decisions of early learners and compare those with outcomes of experienced learners.
- Trial name
- NCT07648212
- Testing
- Review of Radiograph Images
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
pH, Microbiome
Oral Changes With Caloric and no Caloric Sweeteners
The objective of this clinical trial is to compare the effect that the intake of beverages without sweeteners, added with non-caloric sweeteners (stevioside) and caloric sweeteners (sucrose) on oral pH and dental biofilm…
- Conditions
- pH, Microbiome, Dental Plaque
- Trial name
- NCT05852145
- Testing
- Stevioside, Sucrose, Natural water
- Where
- Mexico
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Dental Plaque, Oral Health
Bacterial Arrangement on the Teeth
Background: Dental plaque is a coating of bacteria on the teeth. It contributes to poor dental health and diseases such as gingivitis, cavities and periodontal disease.
- Conditions
- Dental Plaque, Oral Health, Periodontal Disease and Caries, Periodontal Disease
- Trial name
- NCT01712672
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Dental Caries
EFFICACY OF MORUS ALBA FRUIT EXTRACTS AND CHLORHEXIDINE ON SALIVARY STREPTOCOCCUS MUTANS AND pH LEVELS
Dental caries is highly prevalent across the globe including Pakistan and is associated with tooth loss, malocclusion and temporomandibular joint problems and sometimes may cause life threatening infections.
- Trial name
- NCT05052775
- Testing
- Chlorhexidine Mouthwash, Morus Alba 20%, Morus Alba 30%
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Ziauddin University
Deep Caries, Dental Caries
Evaluation of Bioactive Giomer Material Versus Nanohybrid Resin Composite in Deep Marginal Elevation
This study will be conducted to evaluate the clinical, radiographic and periodontal performance of bioactive Giomer compared to nanohybrid resin composite restoration in deep subgingival proximal cavities extending below the CEJ…
- Trial name
- NCT06497231
- Testing
- Beautifil II LS, Nanohybrid resin composite material
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries in Children
Novel Self-Adhesive Composite Hybrid Versus Conventional Composite in Restoration of Carious Primary Teeth.
The clinical trial aim to evaluate clinical effectiveness of self-adhesive composite hybrid (Surefil one) versus conventional composite(VOCO Grandio) as restorative material for carious primary teeth.
- Trial name
- NCT05173753
- Testing
- Novel self-adhesive hybrid composite(Surefil one)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Clinical Performance
Clinical Performance of Nano Fiber Reinforced Versus Conventional Nano Hybrid Composite in Restoring Premolars
In patients that need composite restorations in a compound proximal carious lesions in premolars, will the clinical performance of nano fiber reinforced resin composite restorations have similar results compared to those restored…
- Trial name
- NCT05808075
- Testing
- NovaProTM Fill Universal Dental Composite
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Hypersensitivity
Association of Two Desensitizing Protocols to Control Dentinal Hypersensitivity in Non-carious Lesions
This randomized, double-blind clinical trial evaluated the effect of photobimodulation associated with 8% strontium acetate in the treatment of dentin hypersensitivity in non-carious lesions and analyzed the risk factors with the…
- Trial name
- NCT04642001
- Testing
- Photon Laser III-DMC (without radiation emission) + My First- Colgate, Photon Laser III-DMC (without radiation emission) + Sensodyne® Rapid Relief / GSK, Photon Laser III-DMC (with irradiation emission) + My First- Colgate
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dental Caries, Caries,Dental
Caries Prevalence, Experience and Risk Related Factors Among Early Middle-aged Patients Attending Cairo University
Dental caries, a widespread oral health issue, results from a complex interplay of factors including behavior, hygiene, diet, and socio-demographic aspects.
- Trial name
- NCT06365281
- Where
- Egypt
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Decay, Cavities of Teeth
Plaque Removal Effectiveness of a Flossing Device Compared to the Conventional Flossing in Adults
Objective: To evaluate the effectiveness in plaque removal of the new device; Dental floss holders and compare the results to the conventional way of flossing.
- Conditions
- Tooth Decay, Cavities of Teeth, Gingivitis, Plaque
- Trial name
- NCT06318819
- Testing
- Dental Floss Holders
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maha A. Bahammam
Teeth; Lesion, Dental Root Caries
5-year Clinical Evaluation of Cavity Lining on the Restoration
The purpose of this double-blind, randomized trial is to compare the clinical performance of a composite restorations in root surface carious lesions with or without resin modified glass ionomer lining.
- Trial name
- NCT03802539
- Testing
- Glass Liner
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
White Spot Lesion of Tooth
Efficacy of Different Agents in Treatment of Initial Caries on Smooth Surfaces in Permanent Teeth in Children
White spot lesions (WSL) are characterized by an apparently intact outer surface and a demineralized subsurface, and are considered the first clinical sign of dental caries.
- Trial name
- NCT05206539
- Testing
- Self-assembling peptide (P11-4), CPP-ACFP, Resin infiltration
- Where
- Bulgaria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Caries,Dental, Caries
Using Motivational Interviewing To Reduce Parental Risk-Related Behaviors For Early Childhood Caries
The study's aim was to investigate if a motivational interviewing intervention (MI) improved oral self-care behaviors of AIAN caregivers of infants and determine if the MI intervention promoted positive changes in caregivers' ECC…
- Trial name
- NCT04286256
- Testing
- Motivational Interviewing
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Dental Caries
Clinical Performance of a Highly-filled Flowable Composite in Class III Restorations.
The aim of this study was to evaluate the 12-month clinical performance of a highly filled flowable composite resin in anterior teeth.
- Trial name
- NCT07051551
- Testing
- tooth restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Glass Ionomer Cement, Cost-effectiveness
Effectiveness and Economic Evaluation of Glass Ionomer Material Using as Dental Sealant
Eruption of the first permanent molar is the earliest in our oral cavity, leading to a high occurrence of dental caries in its pits and fissures.
- Conditions
- Glass Ionomer Cement, Cost-effectiveness, Pit and Fissure Caries (Disorder)
- Trial name
- NCT03034837
- Testing
- resin sealant, ART sealant
- Where
- 2 sites in China
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Zhengzhou University
Caries, Dental, Tooth Decay
Efficacy of Solventum™ Vitrebond™ Pulp Protect Liner/Base Used as a Liner/Base Under Dental Restorations
This is a clinical study evaluating a new dental product called Solventum™ Vitrebond™ Pulp Protect Liner/Base. This new product is designed to be used as a liner or base between the tooth and the dental filling, as well as for a…
- Conditions
- Caries, Dental, Tooth Decay, Dental Decay, Tooth Sensitivity
- Trial name
- NCT07261137
- Testing
- Vitrebond™ Pulp Protect Liner/Base, Vitrebond™ Plus (comparator)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Solventum US LLC
Dental Caries
The Anticariogenic Effect of Miswak (Silvadora Persica) and Grape Seed Extract
Prevention of dental caries has taken a great importance in the last decade. The use of herbal and natural products became mandatory to avoid the side effects of commercially available medications.
- Trial name
- NCT04136639
- Testing
- Miswak, Grape Seed Extract Mouthwash, fluoride
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Tooth Decay
One Year Clinical Evaluation of Conservative Versus Conventional Ceramic Onlays
the aim of present study is to evaluate clinically the fracture liability , marginal adaptation , and patient satisfaction of conservative versus conventional ceramic Onlays use e-max press to restore defective restored molar…
- Trial name
- NCT05250232
- Testing
- onlays conservative, onlays conventional
- Volunteers
- 22 people
- Sponsor
- Cairo University
Prevention of Dental Caries
Effect of Bioactive Glass Varnish on Salivary Parameters in Children: Randomized Controlled Trial
This study is a two-arm parallel randomized controlled trial led by Principal Investigator Inas Karawia at the Faculty of Dentistry, designed to evaluate and compare the short-term (immediatly) and sustained (over 6 months)…
- Trial name
- NCT07875387
- Testing
- Bioactive glass topical varnish, Fluoride varnish
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria
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