Clinical trials: Caries, Dental
Dental Caries
Consumption of Probiotics on Salivary Bacteria Causing Dental Caries
Dental caries is a multifactorial disease effecting majority of the human population.One of the etiological factor causing dental caries is salivary mutans streptococci.
- Trial name
- NCT02752594
- Testing
- probiotic
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sharda University
Dental Caries
Effect of Curodont Repair or Placebo on the Remineralisation in Patients With Class 5 Carious Lesions
The purpose of this study is to evaluate the therapeutic benefit of Curodont Repair for the treatment of early buccal carious lesions compared to placebo.
- Trial name
- NCT02020681
- Testing
- Curodont Repair, Fluoride
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Credentis AG
Caries,Dental
CATCH Healthy Smiles:An Elementary School Oral Health Intervention Trial
The purpose of this study is to clinically evaluate the effects of a school-based behavioral intervention, CATCH Healthy Smiles, to reduce the risk of dental caries in a cohort of kindergarten through 2nd grade (K-2) children…
- Trial name
- NCT04632667
- Testing
- Comparison School Group, Intervention School Group
- Where
- United States
- Volunteers
- 1,084 people
- Sponsor
- The University of Texas Health Science Center, Houston
Dental Caries in Children, Dental Plaque
Targeting of Preventive Treatment for Adolescents at Risk of Oral Diseases
The aim of the study is to identify adolescent patients that are at risk of developing oral diseases, and to assess if targeted preventive oral treatment with antibacterial dual-light therapy as an adjunctive treatment method can…
- Conditions
- Dental Caries in Children, Dental Plaque, Tooth Decay, Periodontitis
- Trial name
- LumoPrevent (NCT06286501)
- Testing
- Lumoral Treatment, Standard, personalized oral health care
- Where
- Finland
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Wellbeing Services County of Pirkanmaa
Dental Caries Pit and Fissure, Oral Disease
Effectiveness and Retention of Pit and Fissure Sealants in Rural Setup: A School-based Clinical Trial in Nepal
The program titled "Campus to Community: breaking the barrier in oral health education and dental care" is uniquely designed program to link University (Kathmandu University School of Medical Sciences) to community (Sanghutar…
- Trial name
- NCT05894200
- Testing
- Glass Ionomer cement pit and fissure sealant, Silver Diamine Fluoride
- Where
- Nepal
- Volunteers
- 377 people
- Sponsor
- Kathmandu University School of Medical Sciences
Dental Caries
Evaluation of Anti-biofilm Effects of Ferumoxytol (Feraheme) Using an in Situ Biofilm Demineralization Model
To evaluate the effects of a clinically approved and commercially available iron oxide formulation Ferumoxytol (Feraheme®) to control cariogenic biofilms and enamel demineralization.
- Trial name
- NCT03678012
- Testing
- Ferumoxytol/Hydrogen peroxide, Hydrogen Peroxide, Water
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cervical Caries
Clinical Performance of Short Fiber Reinforced Resin Modified Glass Ionomer Restorations in Cervical Carious Teeth (1y Randomized Clinical Trial)
This research proposal is introduced to clinically test short fiber reinforced glass ionomer material from GC Europe due to gap of knowledge present in this area.
- Trial name
- NCT06185881
- Testing
- restoration of cervical carious teeth
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain During Caries Excavation
Comparison of Intraoperative Pain Perception During Caries Excavation Using Smart Burs and Carisolv to Conventional Diamond Burs
The goal of this randomized controlled trial is to compare the amount of pain experienced during removal of dental caries using Smart burs, Carisolv, and conventional diamond burs in adults aged 18-45 years with active caries in…
- Trial name
- NCT07869407
- Testing
- polymer burs, Carisolv, Conventional Diamond Burs
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Rehman Medical Institute - RMI
Dental Caries in Children
Two Different Minimal Invasive Techniques in Caries Removal of Primary Teeth
Pain control during dental treatments is the most challenging situations that face the pediatric dentist especially in young and fearful or anxious child.
- Trial name
- NCT06759311
- Testing
- ART, Brix 3000, Carie Move
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Hams Hamed Abdelrahman
Tooth Fracture, Tooth Decay
Comparison of Clinical Outcomes of Different Wound Closure Methods in Immediate Implant Placement in the Aesthetic Zone
Implant-supported restorations have become one of the best treatment options for patients with tooth loss, with predictable long-term success rates and clinical outcomes.
- Trial name
- NCT05127629
- Testing
- Immediate implant placement, Guided bone regeneration, Wound closure with gelatin sponge
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Carious Dentin
Postoperative Hypersensitivity and Digital Radiographic Assessment of a Zinc Modified Versus a Conventional Glass Ionomer Cement in Deep Carious Lesion: Randomized Controlled Clinical Trial
The study aim to evaluate the difference between the effect of zinc modified glass ionomer and conventional glass ionomer on the success of partial caries removel technique
- Trial name
- NCT03285022
- Testing
- Partial caries removel techniques
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Self Assembling Peptide P11-4 in Patients With Early Occlusal Carious Lesions
Objectives: Occlusal surfaces of erupting permanent molars are highly prone to caries. Self-assembling peptide (P11-4) has proven to enhance biomimetic mineralization of early carious lesions.
- Trial name
- NCT02724592
- Testing
- self assembling peptide P11-4 (Curodont™ Repair), fluoride varnish (Duraphat®)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Dental Caries
Preventive Effect of a Probiotic Tablet on Oral Health in Preschool Children
The aim of the prospective project is to investigate effect of daily probiotic supplements on dental caries development in preschool children living in a low socioeconomic immigrant area in souithern Sweden.
- Trial name
- NCT01720771
- Testing
- probiotic tablet, sugar pill
- Where
- Sweden
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Caries
In Situ Remineralisation Response of Different Artificial Caries-like Enamel Lesions to Home-care and Professional Fluoride Treatments
This study mainly compared the response of the artificial carious enamel lesions to remineralisation in situ. The tested in vitro demineralising protocols were: MC gel, PA gel, MHDP and Buffer solutions.
- Trial name
- NCT02637830
- Testing
- Application of fluoride varnish (22600 ppm F, Duraphat) at the begining of the study, Application of fluoride toothpaste (1500 ppm F, Crest) twice a day for 3 days of the study
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Antibacterial Effect of Diode Laser
The Microbiological Assessment of Deep Carious Lesions After Step-wise Excavation and Diode Laser Cavity Disinfection .
This study will be conducted to assess antibacterial effect of the diode laser in deep carious cavity after step wise excavation using the bacteriological assessment method.
- Trial name
- NCT03298165
- Testing
- diode laser
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cairo University
Patients With Deep Carious Lesions
Comparative Study Between Biodentine and Mineral Trioxide Aggregate in Direct Pulp Capping
Comparative study between Biodentine and MTA in direct pulp capping of deeply carious teeth.
- Trial name
- NCT02803528
- Testing
- Biodentine, MTA
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
Pulptomy, Dental Caries
Effect of Ferric Sulphate and Putty MTA as Pulpotomy Agent in Vital Primary Teeth
The pulp in primary teeth has a high potential for repair because of high degree of cellularity and vascularity. The rationale for the pulpotomy procedure is that the radicular pulp tissue is healthy and capable of healing after…
- Conditions
- Pulptomy, Dental Caries, Pulp Therapy
- Trial name
- CT (NCT07324928)
- Testing
- Ferric sulphate, Putty MTA
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Jazan
Tooth Decay, Missing Tooth/Teeth
Correlation Study Between Socio-economical Deprivation and Oral Health in Children of 9 Years of Age
Retrospective, observational cohort study. Objectives : To search for correlations between socio-economical deprivation and oral health in french children of 9 years of age.
- Trial name
- PRECA-6 (NCT03817437)
- Where
- France
- Volunteers
- 600,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Dental Caries, Restored Decayed Teeth and Post-operative Sensitivity
Comparative Evaluation of Clinical Success of BIOFLX Crowns and SSC in Primary Molars
Although Stainless steel crowns (SSC) are the gold standard treatment modality for multi-surface carious lesion in paediatric patients, the quest for metal free, aesthetic restoration with comparable features that of SSC still…
- Trial name
- RCT (NCT07465211)
- Testing
- US Public Health Service modified criteria, The parental satisfaction
- Where
- India
- Volunteers
- 36 people
- Sponsor
- satish vishwanathaiah
Dental Caries
Fluoride Varnish Randomized Clinical Trial
The purpose of this study is to compare the efficacy of fluoride varnish (FV) applied once or twice a year with counseling to counseling alone in preventing early childhood caries (ECC) (tooth decay in children under the age of…
- Trial name
- NCT00066963
- Testing
- Fluoride Varnish
- Where
- United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
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