Clinical trials: Caries, Dental
Dental Caries
Phase 2, Open-Label Study for Safety, Microbiology and PK of Single or Multiple Oral C16G2 Gel Doses
Part A: Open-label, multiple arm, safety, microbiology and pharmacokinetic (PK) study in healthy adult male and female subjects 18-75 years of age. All subjects will be assessed for safety and microbiology parameters.
- Trial name
- NCT02254993
- Testing
- C16G2
- Where
- 2 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Armata Pharmaceuticals, Inc.
Pulpal Necrosis, Dental Caries
Comparison of LSTR and Pulpectomy in Primary Molars of Pediatric Patients (LSTR-PULP)
This study aims to compare the effectiveness of Lesion Sterilization and Tissue Repair (LSTR) with conventional pulpectomy in treating pulpal lesions in primary molars of pediatric patients aged 4 to 10 years.
- Conditions
- Pulpal Necrosis, Dental Caries, Periapical Periodontitis, Pediatric Dentistry
- Trial name
- LSTR-PULP (NCT07026435)
- Testing
- LSTR, Pulpectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- taymour abuawwad
Dental Caries
Er,Cr:YSGG Laser Versus Conventional Preparation for Minimally Invasive Caries Removal
This study compared two standard methods for minimally invasive caries removal in children: conventional mechanical excavation and Er,Cr:YSGG laser preparation.
- Trial name
- NCT07493278
- Testing
- Mechanical Caries Removal, Er,Cr:YSGG Laser Caries Removal
- Where
- Bulgaria
- Volunteers
- 32 people
- Sponsor
- Medical University of Sofia
Deep Caries, Caries, Dental
Performance of Bioactive Low Viscosity Composite in Deep Marginal Elevation Restorations
The goal of this study is to evaluate the clinical, radiographic and periodontal performance of bioactive Giomer Shofu Flow Plus X F03 compared to nanohybrid resin composite restoration in deep subgingival proximal cavities over…
- Trial name
- NCT06882343
- Testing
- Beautiful Flow Plus X, Dentsply Nanohybrid flowable composite
- Volunteers
- 50 people
- Sponsor
- Future University in Egypt
Dental Caries
6-year Clinical Evaluation of Glass Ionomer Cements (GIS) With Resin Coating on Posterior Teeth
The aim of this study was to evaluate the long-term clinical performance of two highly viscous encapsulated GICs (EquiaFil and Riva SC) covered with two different coatings (Equia Coat and Fuji Varnish) over 6-year using modified…
- Trial name
- GIS (NCT02616198)
- Testing
- EquiaFil G-coat, EquiaFil Fuji Varnish, Riva SC G-coat
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ege University
Deep Carious Lesions, Reversible Pulpitis
Indirect Pulp Capping With Biodentine and TheraCal LC in Permanent Mature Molars
Management of deep carious lesions in permanent mature molars with reversible pulpitis represents a challenge for clinicians. Vital pulp therapy includes indirect and direct pulp capping, partial pulpotomy and full pulpotomy.
- Conditions
- Deep Carious Lesions, Reversible Pulpitis, Indirect Pulp Capping
- Trial name
- NCT03741816
- Testing
- Indirect pulp capping
- Where
- Spain
- Volunteers
- 212 people
- Sponsor
- University of Valencia
White Spot Lesion
Effectiveness of Different Remineralizing Strategies on the Management of Early Carious Lesions in Primary Teeth
the primary aim of the study is remineralization of early carious lesions in primary teeth using different remineralizing agents of different remineralizing strategies when applied in an intensive mode.
- Trial name
- NCT06566833
- Testing
- self assmbling peptide p11-4 combined with 0.05% fluoride, Casein phosphopeptide amorphous calcium phosphate, 5% sodium fluoride varnish
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dental Caries in Children, Dental Diseases
Gurney Journey: Virtual Reality Distraction
The aim of this study is to determine whether a software virtual reality (VR) program provided during transportation to anesthesia induction reduces anxiety before the procedure, and compliance in pediatric patients.
- Conditions
- Dental Caries in Children, Dental Diseases, Gastrointestinal Surgery, Procedures Requiring Anesthesia
- Trial name
- NCT06283108
- Testing
- Standard Child Life Preparation and Support + Meta Quest 2 VR headset with Gurney Journey (a mixed reality experience), Standard Child Life Preparation and Support
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Colorado
Class I Dental Caries
Clinical Performance and Wear Resistance of Two Nano Ceramic Resin Composite in Class I Cavities
in patients with Class I Cavities, will the use of Zenit Nano Ceramic Composite restorations have similar clinical performance to conventional Ceram-X Nano Ceramic Composite restorations, evaluation of restorations will be done…
- Trial name
- NCT04738604
- Testing
- Ceram•X (Dentsply De Trey GmbH, Konstanz, Germany, Zenit Nano Ceramic Composite (PRESIDENT DENTAL, GmbH, Munich, Germany)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries in Children, Knowledge, Attitudes, Practice
The Effect of Oral Health Education on Knowledge, Attitude, Practice and Dental Caries Among Egyptian School Children
Aim of the study Assessing the effect of an oral health education program on knowledge, attitude, practice, and dental caries among a group of school children in a governmental school in Fayoum, Egypt.
- Trial name
- KAP (NCT06280547)
- Testing
- Oral health education
- Where
- Egypt
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cervical Caries
Clinical Performance of Bioceramic vs High Viscosity GIC for Cervical Restorations of Geriatric Patients
The aim of this study is to clinically evaluate the performance of the bioceramic glass ionomer compared to conventional high viscosity glass ionomer for restoration of carious cervical lesions in geriatric patients over 12…
- Trial name
- NCT05624008
- Testing
- Bioceramic glass ionomer restoration, Resin modified glass ionomer restoration
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Decay, Dental, Missing Teeth
Relationship Between Oral Findings and Salivary Factors in Sars-Cov-2 Patients
Two hundred individuals will be formed according to the study and control groups: Group-1: coronavirus 2 (Covid-19) (+) patients (n=100) and Group-2: Healthy individuals (in which the volunteers will be included due to group-1)…
- Conditions
- Decay, Dental, Missing Teeth, COVID-19, Cytokine Storm
- Trial name
- NCT05476848
- Testing
- ELISA test for Cytokines
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Ege University
Dental Caries, Primary Teeth
Non-Restorative Versus Conventional Caries Treatment in Primary Teeth: A Randomized Controlled Trial
Dental caries is common in young children, and treatment of cavities in primary teeth can be challenging. Conventional treatment usually involves removal of carious tooth tissue and placement of a restoration.
- Trial name
- NRCT (NCT07866755)
- Testing
- Non-restorative caries treatment (NRCT), CT
- Where
- Slovenia
- Volunteers
- 96 people
- Sponsor
- Lenka Likar Ostrc, DMD
Dental Caries, Cervical Caries
Clinical Performance of High Viscous Glass Ionomer Cervical Restorations With Silver-Modified Atraumatic Restorative Technique (SMART) Versus Conventional Treatment in Elderly Cancer Patients. (A 12-month Randomized Clinical Trial)
This study will evaluate the clinical performance of glass ionomer cervical restorations placed using the Silver-Modified Atraumatic Restorative Technique (SMART) compared with conventional restorative treatment in elderly cancer…
- Trial name
- NCT07803757
- Testing
- Silver Diamine Fluoride (SDF, 38%), Conventional Tooth Preparation, High-Viscosity Glass Ionomer Cement
- Volunteers
- 30 people
- Sponsor
- Cairo University
Caries Experience
Evaluation of Dental Caries Using Caries Assessment Spectrum and Treatment Need (CAST) Index, International Caries Detection and Assessment System (ICDAS) Index and World Health Organization (WHO) Index
This study goals is to compare the three indices in Egyptian children aged 4 to 6 years in caries detection and time needed for the assessments which will contribute to valuable data for pediatric oral health assessments both…
- Trial name
- CAST/ICDAS/WHO (NCT06858462)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cervical Caries
Clinical Evaluation of Self-Adhesive Flowable Giomer With and Without Selective Enamel Etching
This randomized clinical trial is to evaluate the clinical performance of the self-adhesive flowable Giomer with and without selective enamel etching compared to flowable Giomer using standard bonding protocol in class V cavity…
- Trial name
- NCT07575646
- Testing
- Beautifil Flow Plus F00, FIT SA after selective enamel etching, FIT SA
- Volunteers
- 75 people
- Sponsor
- Cairo University
Tooth Decay
COMPARISON OF SECTIONAL MATRIX VERSUES CIRCUMFERENTIAL MATRIX FOR RECONSTRUCTION OF PROXIMAL CONTACT IN CLASS 2 RESTORATIONS
Class II caries affects proximal surfaces of premolars and maintain their anatomical proximal contact of tooth, is important to avoid food impaction in the interdental area for protection of periodontium and occurrence of…
- Trial name
- NCT05734027
- Testing
- Sectional matrix, Circumferential matrix
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Dental Caries
Microbial Testing for Caries Risk Assessment
Specific Aims 1) Assess CG (Cariogenic) Saliva-Check Mutans® saliva testing for identification of high caries risk patients
- Trial name
- NCT03389373
- Testing
- GC Strep Mutans Saliva Sampling
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Caries; Initial, Occlusal Caries
Early Treatments for Preventing Occlusal Caries Lesions
Sealants effectively arrest non-cavitated caries lesions on the fully erupted occlusal surface of permanent teeth. However, the clinical effectiveness of sealants is uncertain in preventing occlusal caries lesions in partially…
- Conditions
- Caries; Initial, Occlusal Caries, Caries,Dental
- Trial name
- NCT05969756
- Testing
- Fluoride varnish, Conventional etch and rinse sealant, Self-etch sealant
- Where
- 2 sites in Vietnam
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hue University of Medicine and Pharmacy
Dental Caries, Pulpitis
Comparison of Mineral Trioxide Aggregate (MTA) and 20% Formocresol (FC) in Pulpotomized Human Primary Molars
This prospective clinical randomized controlled trial is established to compare the clinical, radiographic, and histological treatment outcomes between MTA and FC in pulpotomized human primary molars at 6, 12, 18, 24 month…
- Trial name
- NCT00972556
- Testing
- Gray Mineral Trioxide Aggregate (GMTA), Diluted (20%) Formocresol (DFC)
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.