Clinical trials: Caries, Dental
Dental Caries
Arresting Active Dental Caries in Preschool Children by Topical Fluorides
This randomized clinical trial aims to compare the effectiveness of three topical fluoride application protocols, namely three applications of a 30% SDF solution at yearly or weekly interval and three applications of a 5% NaF…
- Trial name
- NCT02426619
- Testing
- SDF solution, NaF varnish
- Where
- China
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dental Caries, Unsatisfactory or Defective Restoration of Tooth
Clinical Evaluation of a Bulk Fill Resin Composite
The purpose of this clinical trial is to measure the clinical outcomes of Tetric PowerFill Class I and II restorations cured in 3 seconds with the Bluephase PowerCure curing unit.
- Trial name
- NCT04686422
- Testing
- Tetric PowerFill
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Ivoclar Vivadent AG
Cariostatic Agents, Mouthwashes
Anticaries Effect of Xylitol,Probiotic and Chlorhexidine Mouth Rinses Among Individuals at High Risk
Dental caries is a localized, post eruptive pathological process involving softening of the hard tooth tissue and proceeding to the formation of cavity.
- Trial name
- AEXPC (NCT04399161)
- Testing
- Chlorhexidine mouthwash, Xylitol, Probiotic
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Dr. Krupa NC
Oral Health, Dental Caries
Improved Oral Health and Dental Care in Children with Congenital Heart Disease
Background: Congenital heart disease (CHD) is one of the most common congenital anomalies in children. As the risk for endocarditis following bacteraemia is more common during daily oral hygiene routines, such as tooth brushing…
- Trial name
- ORALPEDHEART (NCT03329170)
- Testing
- educational intervention using motivational interviewing
- Where
- Finland
- Volunteers
- 150 people
- Sponsor
- My Blomqvist
PreTerm Birth
Prevalence of Dental Caries in Preterm Birth Children Aged 2-5 Years in Primary Dentition
The purpose of the study is to determine the prevalence of dental caries in preterm birth children aged 2-5 years in primary dentition.
- Trial name
- NCT02999061
- Where
- Egypt
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- Cairo University
Clinical Trial, Dental Caries
Clinical Evaluation of Class I Direct and Indirect Restorations Over 10 Years
This clinical study aims to evaluate and compare the long-term clinical performance of direct and indirect restorations in Class I cavities of molar teeth over a 10-year period.
- Trial name
- NCT07081529
- Testing
- Direct Restoration with Microhybrid Composite, Indirect Restoration with Reinforced Microfill Composite
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Caries, Dental, Fluorosis, Dental
Dental Fluorosis Risk by the Use of Acidulated Fluoride Dentifrice
This research aimed to evaluate the risk of dental fluorosis by using an experimental fluoridated acidulated dentifrice compared to conventional dentifrices in two-to-four-year-old children residing in a non fluoridated area by…
- Trial name
- NCT03761485
- Testing
- Use of Dentifrice Fluoride
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Dental Caries in Children
Impact of Oral Health Program on Al-Lith Children's KAP
Dental caries remains a significant global public health issue, particularly affecting children's health, development, and well-being, with inadequate knowledge, attitudes, and practices around oral health exacerbating these…
- Trial name
- NCT07009015
- Testing
- The oral health education intervention program
- Where
- Malaysia
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Vitamin D Deficiency, Dental Caries
Maternal Vitamin D Levels in Pregnancy and Dental Caries in Children
The main aim of this study is to investigate potential associations between maternal pre- and postnatal vitamin D level and oral health outcomes (caries and developmental defects of enamel) in their children at 7-9 years of age.
- Conditions
- Vitamin D Deficiency, Dental Caries, Dental Enamel Hypoplasia
- Trial name
- NCT03273725
- Testing
- Dental examination including taking a saliva sample.
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Tannhelsetjenestens Kompetansesenter Midt-Norge
Dental Caries
SDF Application in Oral Cancer Patients to Prevent Dental Caries
The Texas A \& M College of Dentistry, with partner Texas Oncology-Baylor Charles A. Sammons Cancer-Center Radiation-Oncology, proposes to conduct a preliminary clinical study (NIH Stage 0) to pilot test a randomized clinical…
- Trial name
- NCT05403125
- Testing
- silver diamine fluoride, 38%, Sodium fluoride gel, 5000 PPM
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Texas A & M University Baylor College Of Dentistry
Dental Caries in Primary Molars in Children
Comparison of Smart Burs , Atraumatic Restorative Treatment and Gentle Hand Burs for Caries Removal in Children
This study compared three gentle ways of removing tooth decay in children's primary molars:Gentle hand burs(new hand held rotary instrument used withot electricity),Smart burs (polymer burs used in a slow speed hand piece) and…
- Trial name
- NCT07857785
- Testing
- Gentle Hand Burs, Atraumatic Restorative Treatment, Smart Burs(polymer bur)
- Where
- India
- Volunteers
- 90 people
- Sponsor
- Sathiraju Hema Sai Niharika
Dental Caries, Cavity, Dental
Clinical Performance of CAD/CAM Hard Hybrid Ceramic Inlays Versus Resin Composite Inlays in Vital Molars With Extensive Occluso-Proximal Cavities
this study aims to compare the clinical performance of hard hybrid ceramics and composite resin indirect restorations fabricated by CAD/CAM technology for the vital teeth with occluso-proximal cavities.
- Conditions
- Dental Caries, Cavity, Dental, Proximal Dental Caries
- Trial name
- NCT07648485
- Testing
- hybrid ceramics, Composite resin
- Volunteers
- 50 people
- Sponsor
- Cairo University
Early Childhood Caries (ECC), Dental Caries
Effect Of Three Remineralizing Agents On Early Childhood Caries
Early Childhood Caries (ECC) remains a global public health concern, necessitating minimally invasive, fluoride-based alternatives to conventional restorative therapy.
- Trial name
- SDF (NCT07371117)
- Testing
- Silver Diamine Fluoride (SDF, 38%), Sodium Fluoride with CPP-ACP, Acidulated phospahate fluoride gel 1.23%
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- University of Jazan
Periodontal Disease, Periapical Disease
Periodontal and Periapical Inflammation and Pregnancy
This is a retrospective chart review of patient records at the University of Mississippi Medical Center. We are not actively recruiting patients for this study.
- Conditions
- Periodontal Disease, Periapical Disease, Pregnancy, Diabetes
- Trial name
- NCT00490165
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Roger Johnson
Deep Carious Lesions
Radiographic Assessment of Calcific Bridge Formation by Light Activated Calcium Silicate Versus Calcium Hydroxide for Deep Caries
sixty participants will be divided in to two groups (n=30) of patient treated by partial caries removal according to the capping material (A),where (A1)represents calcium silicate group,(A2)represent calcium hydroxide group.Apply…
- Trial name
- NCT03233893
- Testing
- light activated calcium silicate
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Nutrition Disorders in Old Age, Caries,Dental
LifE Style, Nutrition and Oral Health in Care Givers (LENTO)
The LENTO study sample includes the caregivers and their clients living in eastern Finland. The aims of this study are 1. to study the nutritional status, oral health, coping, functional capacity and quality of life 2.
- Conditions
- Nutrition Disorders in Old Age, Caries,Dental, Dentures, Oral Mucositis
- Trial name
- NCT04003493
- Testing
- Nutrition and oral health intervention
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Dental Caries, Cervical Caries
Clinical Performance of High Viscous Glass Ionomer Cervical Restorations With Silver-Modified Atraumatic Restorative Technique (SMART) Versus Conventional Treatment in Elderly Cancer Patients. (A 12-month Randomized Clinical Trial)
This study will evaluate the clinical performance of glass ionomer cervical restorations placed using the Silver-Modified Atraumatic Restorative Technique (SMART) compared with conventional restorative treatment in elderly cancer…
- Trial name
- NCT07803757
- Testing
- Silver Diamine Fluoride (SDF, 38%), Conventional Tooth Preparation, High-Viscosity Glass Ionomer Cement
- Volunteers
- 30 people
- Sponsor
- Cairo University
Dental Caries, Periodontal Diseases
Xylitol Chewing-gums: Concentration in Saliva and Antibacterial Effect
a double-blind cross-over in vivo study was performed to measure the salivary concentration of Xylitol released from the two chewing gums containing different amount of the polyol.
- Trial name
- NCT03971981
- Testing
- 100% Xylitol Gum, 22% Xylitol Gum
- Where
- Italy
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Dental Caries, White Spot Lesion
A Randomized Controlled Trial of Vitamin D Supplementation on Salivary Biomarkers and Cariogenic Oral Microbiome
The goal of this clinical trial is to compare the treatment effect of vitamin D supplementation and topical fluorides in the population having vitamin D deficiency and Initial Carious Lesions (ICL) on the progression of ICL in…
- Conditions
- Dental Caries, White Spot Lesion, Initial Caries, Incipient Enamel Caries
- Trial name
- Incipient (NCT06172764)
- Testing
- Vitamin D supplements along with behavioral modification, Topical fluoride application and Vitamin D supplements along with behavioral modification, Topical fluoride application along with behavioral modification
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Teledentistry
Accuracy of Teledentistry for Diagnosis and Treatment Need in Dental Caries Detection Versus Clinical Examination on a Group of Egyptian Children: A Diagnostic Accuracy Study
The aim of this study is to assess the accuracy of teledentistry for diagnosis and treatment need in dental caries detection versus clinical examination on a group of Egyptian children.
- Trial name
- NCT06600360
- Testing
- Teledentistry
- Volunteers
- 102 people
- Sponsor
- Cairo University
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