Clinical trials: Caries, Dental
Pediatric Dental General Anesthesia, Restoration
Clinical Performance and Failure Rates of Restorations Following Pediatric Dental Rehabilitation Under General Anesthesia
Full-mouth dental rehabilitation under general anesthesia (GA) is frequently required for young children with extensive dental caries, behavioral challenges, or special healthcare needs.
- Conditions
- Pediatric Dental General Anesthesia, Restoration, Clinical Performance, Full Mouth Rehabilitation
- Trial name
- NCT07827833
- Testing
- Routine Restorative Materials and Treatment Methods
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Tanta University
Caries,Dental
The Effect of Casein Phosphopeptide Amorphous Calcium Phosphate on Affected Dentine
Teeth selected for intervention with Atraumatic Restorative Treatment will receive Glass Ionomer restorations (control) or MI varnish (test) before receiving the Glass Ionomer restoration
- Trial name
- NCT04303767
- Testing
- Casein phosphopeptide amorphous calcium phosphate, Atraumatic restorative treatment
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hams Hamed Abdelrahman
Dental Caries, Primary Teeth
Discomfort Evaluation During Atraumatic Restorative Treatment in Children
This study evaluates the patient 's discomfort when submitted to partial caries removal through the atraumatic restorative treatment compared to chemo-mechanical caries removal using Papacarie™ gel.
- Conditions
- Dental Caries, Primary Teeth, Post Dental Restoration
- Trial name
- NCT03143387
- Testing
- Caries removal using only manual instruments, Caries removal using Papacarie gel
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
HIV Infections
Safety and Efficacy Study of KP-1461 to Treat ART-Experienced HIV+ Patients
The primary purpose of the study is to investigate the safety and efficacy of KP-1461 given every 12 hours for 124 days to HIV+ patients who have failed multiple antiretroviral regimens.
- Trial name
- NCT00504452
- Testing
- KP-1461
- Where
- 31 sites in United States, Puerto Rico
- Volunteers
- 27 people
- Sponsor
- Koronis Pharmaceuticals.
Dental Pulp Capping, Dental Caries Extending to Pulp
Long-term Evaluation of Direct Pulp Capping
Calcium hydroxide and mineral trioxide aggregate have been used in vital pulp therapy with variable outcomes recorded by different study.
- Trial name
- NCT03403985
- Testing
- Calcium Hydroxide (Ca(OH)2), Mineral Trioxide Aggregate
- Where
- Jordan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Destructed Teeth Restored by Zirconia Crowns, Zirconia Crowns
Clinical Outcomes of Bonded Monolithic Translucent Zirconia Crowns Using Two Different Compositions of Self-adhesive Resin Cements
The aim of the present study is to evaluate the clinical outcomes (marginal discoloration, marginal adaptation, gingival health, debonding and patient satisfaction) of translucent zirconia crowns bonded by TheraCem (MDP, calcium…
- Conditions
- Destructed Teeth Restored by Zirconia Crowns, Zirconia Crowns, Decayed, Missing, and Filled Teeth, Tooth Discoloration
- Trial name
- NCT04875468
- Testing
- TheraCem self-adhesive resin cement, Multilink adhesive resin cement
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Diana Mostafa Habeb
Dental Caries, Knowledge
Implementation of Oral Health Educational Program on Orphan Children
Oral diseases are most prevalent among children. Orphans children are one of the most vulnerable groups to diseases especially oral diseases.
- Conditions
- Dental Caries, Knowledge, Practice
- Trial name
- NCT06428474
- Testing
- Health education
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Pharos University in Alexandria
Dental Caries, Class I Dental Caries
Effect of Surface Sealant Application on Clinical Performance Occlusal Restorations
The aim was to evaluate the clinical performance of HEMA-containing and HEMA-free all-in-one self-etch adhesives with and without a surface sealing process with a nanohybrid composite in occlusal caries restorations.
- Conditions
- Dental Caries, Class I Dental Caries, Dental Composite
- Trial name
- NCT03184025
- Testing
- dentin adhesive
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Neslihan Tekçe
Dental Caries
SEALANT-DK: Longevity and Efficacy of 6 Resin Sealants Used for Sealing Permanent Teeth in Children and Adolescents
Background: Occlusal caries is the main reason for restorative therapy in the young permanent dentition, but restorations have limited survival time and may also weaken the tooth.
- Trial name
- SEALANT-DK (NCT02561689)
- Testing
- Fissure sealing
- Where
- Denmark
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Caries
The Tayside Brushing Study - Adult Follow up
Historically dental health of Scottish children had been poor for many years. Evidence form clinical trials of fluoride toothpaste identified a route to improving prevention.
- Trial name
- NCT02623283
- Testing
- No intervention given
- Where
- United Kingdom
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- NHS Tayside
Dental Caries
Early Childhood Caries Prevention at a Pediatric Clinic
This purpose of this study was to evaluate effectiveness of a risk-based dental caries prevention program conducted by dental personnel at an urban pediatric primary care clinic serving largely low-income residents of Baltimore…
- Trial name
- NCT00497029
- Testing
- fluoride varnish, patient education
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Tooth Crown Fracture, Dental Caries
Clinical Performance of Ceramic CAD/CAM Crowns
The purpose of this study was to evaluate the clinical performance of laboratory and chairside fabricated monolithic anterior and posterior LDGC CAD/CAM crowns performed by predoctoral students at the University of Toronto and…
- Trial name
- NCT03921307
- Where
- Canada
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Dental Caries
Parental Satisfaction of Hall Technique for Caries Management in Primary Molars
As a newly introduced technique for caries management in primary teeth, patient-centered outcomes such as parental satisfaction, acceptability of the treatment and child discomfort needs to be investigated about Hall technique.
- Trial name
- NCT07148401
- Testing
- Hall technique
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- National Research Centre, Egypt
Dental Caries
Clinical Performance of a Glass-ionomer Restorative System: A 6-year Evaluation
The aim of this clinical trial was to compare the clinical performances of a glass ionomer restorative system with a micro hybrid resin based composite in class I and class II cavities.
- Trial name
- NCT02888912
- Testing
- EQUIA, Gradia Direct Posterior
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Caries,Dental
Maximal Use Study to Determine the Pharmacokinetics of L-arginine After Exaggerated Oral Use of COL101
Pharmacokinetic (PK) study of L-arginine after exaggerated oral use of the novel dentifrice product COL101 after repeated daily applications in healthy adult subjects.
- Trial name
- NCT06182267
- Testing
- L Arginine, Sodium Fluoride
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Caries
SDF With or Without Fluoride Varnish for Caries Arrest in Primary Teeth of Young Children
Tooth decay (dental caries) occurs when acids dissolve tooth structure. If not treated, cavities in primary teeth can progress quickly, leading to caries, infection and early tooth loss.
- Trial name
- SDF-FV (NCT07153328)
- Testing
- Silver Diamine Fluoride (SDF, 38%) and Sodium Fluoride Varnish (NaF, 5%), Silver Diamine Fluoride (SDF, 38%)
- Where
- 2 sites in Albania
- Volunteers
- 104 people
- Sponsor
- Beaty Dent
Dental Caries
Partial Removal of Caries Dentines
The aim of this multicenter randomized controlled clinical trial is to evaluate the effectiveness of an alternative treatment for deep caries lesions in Public Health Services.
- Trial name
- PRCD (NCT00887952)
- Testing
- Partial removal of carious dentine, Stepwise excavation
- Where
- 2 sites in Brazil
- Volunteers
- 329 people
- Sponsor
- Federal University of Rio Grande do Sul
Decayed Teeth
Custom-made Versus Prefabricated Zirconia Crowns for Primary Molars.
Background: Do construction methods of pediatric zirconia crowns affect the periodontal health and clinical performance of badly decayed primary molars? The question asked by many practitioners.
- Trial name
- NCT04620174
- Testing
- Custom-made zirconia crowns, Prefabricated zirconia crowns
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Dental Caries (Diagnosis), Artifical Intelligence
Accuracy Of Detection Of Dental Caries From Intraoral Images Using Different ArtificiaI Intelligence Models
The goal of this observational study is to evaluate the diagnostic accuracy of different deep learning models in detecting dental caries from intra oral images taken by a professional intra oral camera in children.
- Conditions
- Dental Caries (Diagnosis), Artifical Intelligence, Intraoral Images
- Trial name
- NCT06749743
- Testing
- FASTER RCNN
- Where
- Egypt
- Volunteers
- 398 people
- Sponsor
- Cairo University
Overweight
Delivering Geospatial Intelligence to Health Care Providers
Physician counseling for physical activity, dental services, and academic support services such as tutoring could be improved through physician knowledge of local community resources and physician counseling directing patients to…
- Trial name
- CHICA GIS (NCT01567228)
- Testing
- CHICA GIS (enhanced electronic medical record)
- Where
- United States
- Volunteers
- 1,076 people
- Sponsor
- Indiana University
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