Clinical trials: Caries, Dental
Dental Caries
Telemedicine and Forensic Odontology
The aim of this study is to identify the expectations of experts in forensic odontology on telemedicine. This study could improve, in multiple cases post mortem body identification.
- Trial name
- NCT05305157
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Dental Caries
the Effect of Prenatal Vitamins on the Tooth Structure
the effect of mother prenatal care on the teeth of the newborn children, if it affect the tooth structure or not
- Trial name
- NCT03598972
- Testing
- intervention
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Masticatory Performance in Mixed Dentition Children Before and After Dental Treatment
This prospective clinical study aimed to evaluate the effects of dental treatment on masticatory performance and food preferences in children during the mixed dentition period.
- Trial name
- NCT07271901
- Testing
- Dental Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- TC Erciyes University
Dental Caries in Children
Salivary Antioxidant Capacity Before and After Complete Dental Rehabilitation
Salivary samples were obtained from 20 children in their fifth year of life diagnosed S-ECC and 20 age and sex matched controls.
- Trial name
- NCT03432728
- Testing
- Dental rehabilitation under general anesthesia
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Molar Incisor Hypomineralisation, Dental Caries
Selective Versus Non-selective Caries Excavation in MIH Affected Teeth.
The aim of this study is to compare the clinical and radiographic outcomes of selective versus nonselective caries removal in MIH affected teeth with deep carious lesions using enhanced clinical protocols.
- Trial name
- NCT07142629
- Testing
- Selective caries removal, Non-Selective caries removal
- Where
- Jordan
- Volunteers
- 60 people
- Sponsor
- King Abdullah University Hospital
Caries, Dental, Caries; Dentin
3D-printed Ceromer Crowns Versus Stainless Steel in Posterior Primary Molars
The aim of the study is to compare preformed metal crowns and 3D-printed ceromer crowns in primary molars of 4-9 years old children.
- Conditions
- Caries, Dental, Caries; Dentin, Dental Caries in Children
- Trial name
- NCT07091331
- Testing
- Personalized 3D-printed pediatric ceromer crown, Prefabricated stainless steel crown group
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Universidad Autonoma de Baja California
Poliomyelitis
Duration of IPV Priming and Antibody Decay
This is an open-label randomized phase IV clinical trial assessing immunogenicity of poliovirus vaccines.Participants will be enrolled at 6 weeks of age and followed to 18 months of age.
- Trial name
- NCT03202719
- Testing
- Bivalent oral poliovirus vaccine (bOPV) at 6,10 and 14 weeks of age, Inactivated poliovirus vaccine (IPV) at 14 weeks and 18 months of age, Inactivated poliovirus vaccine (IPV) at 14 weeks, 18 weeks and 18 months of age
- Where
- 2 sites in Bangladesh
- Volunteers
- 1,645 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Decayed Teeth
Effect of Bone Marrow Mononuclear Cell Layer Seeded on Platelet-rich Fibrin on an Alveolar Socket After Extraction
Bone marrow aspiration from maxillary tuberosity will be centrifuged to separate the bone marrow mononuclear cell layer using the density gradient separation method, then it will be seeded in a platelet-rich fibrin membrane and…
- Trial name
- NCT05465421
- Testing
- bone marrow aspiration from maxillary tuberosity and BMMNCs separation to be seeded on PRF and used for socket preservation
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Orthodontics, White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Orthodontic Treatment on Oral Microbiota and Salivary Proteins
Study on the changes in oral microbiota during orthodontic treatment in patients aged 8-18 years. Orthodontic patients treated at Stomatology Hospital of Xi'an Jiaotong University from March 2025 to March 2027 will be recruited.
- Conditions
- Orthodontics, White Spot Lesions [Initial Caries] on Smooth Surface of Tooth, Caries, Dental
- Trial name
- NCT06824493
- Testing
- no interventions, No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Xi'an Jiaotong University
Dental Caries in Children
3D-printed Crowns Versus Zirconia Crowns for Primary Molars
The aim of the present study is to compare between 3D-printed crowns and prefabricated zirconia crowns for restoring pulpally-treated primary molars regarding the following aspects: 1.
- Trial name
- NCT06068244
- Testing
- 3D printed crowns, Zirconia crowns
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries, Minimally Invasive
Sealing Defective Margins of Composite Restorations With Fluid Composite Resin Nanofiller Reinforced
the patient (n=60), with at least 3 composite resins with marginal defects , randomized into 3 groups A=Sealed with flow composite reinforced with nanofiller , B= Sealed with resin sealant , and C=Control, without intervention …
- Conditions
- Dental Caries, Minimally Invasive, Repair
- Trial name
- SEAL2 (NCT03214445)
- Testing
- Sealing margins with flow composite, Sealing margins with seal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Chile
Dental Caries (Diagnosis), Dental Plaque (Diagnosis)
Intra Oral Scan and CBCT Aided Diagnosis of Dental Plaque and Caries
In this prospective controlled trial, patients will be enrolled at the University Hospital Ghent. Inclusion criteria are: age between 18 and 70 years old, presence of 20 or more teeth, and have a minimum one carious tooth…
- Trial name
- NCT06945354
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University Ghent
Dental Caries, Oral Disease
Fluoride Varnish Community Trial
This cluster-randomized controlled community trial aimed to assess the efficacy and costs of fluoride varnish application for caries prevention in a high-risk population in South Africa.
- Conditions
- Dental Caries, Oral Disease, Costs
- Trial name
- NCT03429829
- Testing
- Flairesse varnish
- Where
- 2 sites in South Africa
- Volunteers
- 513 people, healthy volunteers welcome
- Sponsor
- DMG Dental Material Gesellschaft mbH
Anxiety Disorders, Oral Disease
Effect of Trait Anxiety in Women on Oral Health Status and Oral Health Care-Seeking Behavior
Trait anxiety is the tendency of an individual to perceive environmental stimuli such as different events and situations as threatening; it's stable and reflects how an individual generally feels.
- Conditions
- Anxiety Disorders, Oral Disease, Periodontal Diseases, Periodontal Attachment Loss
- Trial name
- NCT04274855
- Where
- Egypt
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Early Childhood Dental Caries
Development and Evaluation of a Medical Intervention for Early Childhood Caries
This study aimed to evaluate the effect of three forms of continuing medical education (CME) on provision of preventive dental services to Medicaid-enrolled children by medical personnel in primary care physician offices.
- Trial name
- IMB-RCT (NCT00464009)
- Testing
- Continuing medical education
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Oral Health Related Quality of Life (OHRQoL), Early Childhood Caries (ECC)
Assessment of Oral Health-Related Quality of Life in Preschool-Aged Children in Alto Alentejo
The observational study aims to improve understanding of Oral Health-Related Quality of Life (OHRQoL) among preschool children in the District of Portalegre, Portugal, by examining the roles of sociodemographic, behavioral, and…
- Conditions
- Oral Health Related Quality of Life (OHRQoL), Early Childhood Caries (ECC), Traumatic Dental Injuries, Gingivitis
- Trial name
- NCT07648121
- Where
- Portugal
- Volunteers
- 454 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Dental Caries
In Vivo Evaluation of an Experimental Fluoride-containing Dentifrice With Hydrocolloid
The literature recognizes that fluoride is the most widely used and studied means for dental remineralization. The use of fluoride toothpaste in brushing is considered more rational method for the prevention of caries.
- Trial name
- FdentifriceT (NCT02809014)
- Testing
- Dentifrice F-Complex, Dentifrice F-Complex + NaF, Dentifrice standard
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Fabio Correia Sampaio
Dental Caries
Prevention of Enamel Demineralization by Use of K18-smooth Surface Sealant
This study will evaluate effectiveness of a urethane dimethacrylate (UDMA)-quaternary ammonium methacrylate (K18) resin (UDMA-K18) smooth surface sealant to prevent biofilm attachment to tooth surfaces thereby eliminating the…
- Trial name
- K18 (NCT03306433)
- Testing
- UDMA-K18 smooth surface sealant
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pulpitis, Caries Active
Hydraulic Cements in Partial Pulpotomy
This study is a randomized clinical trial that compares two types of hydraulic cements used in partial pulpotomy procedures for permanent teeth affected by deep decay and pulp inflammation.
- Trial name
- NCT06881615
- Testing
- MTA PLACEMENT FOR PP, PUTTY PLACEMENT FOR PP
- Where
- Spain
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Dental Caries
DPBRN Prevalence of Questionable Occlusal Caries Lesions
The purpose of this study was to investigate the process involved when making decisions about the diagnosis and treatment of questionable lesions, as well as determine if there is any association between lesions progression (or…
- Trial name
- NCT01201447
- Where
- 7 sites in United States, Denmark
- Volunteers
- 2,624 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
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