Clinical trials: Caries, Dental
Dental Caries
Oral Alkali Production and Caries Prevention in Children (Cross-sectional Component)
The fact that dental caries remains a major public health problem mandates that oral-health researchers explore new strategies for assessment of caries risk, as well as for caries prevention and management.
- Trial name
- NCT02368028
- Testing
- Oral Samples
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- University of Florida
Dental Caries
AI-Based Detection of Dental Caries in Children
This study aims to evaluate the effects of an artificial intelligence (AI)-based caries detection system on the diagnosis and categorization of dental caries in pediatric patients.
- Trial name
- NCT06984029
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Noura Nageh Ramadan Ahmed
Caries,Dental
Caries Detection With Two Different Caries Detecting Devices
The primary aim of this study will be to compare the effectiveness of the novel LumiCare™ rinse and with QLF in determining caries progression.
- Trial name
- NCT06152081
- Testing
- LumiCare rinse, QLF Inspektor Pro Imaging
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tufts University
Dental Caries, Cervical Caries
The Effectiveness RMGI and Giomer, Individually and Combined Anterior Cervical Caries
This study compares the effectiveness of three dental materials for restoring anterior cervical caries in high-risk patients: resin-modified glass ionomer (RMGI), Giomer, and a combination technique where RMGI is veneered with…
- Trial name
- NCT06901453
- Testing
- Low shrinkage Giomer restorative material (Beautifil II LS), RMGI alone - Control
- Volunteers
- 75 people
- Sponsor
- Cairo University
Dental Caries
Effectiveness of Coconut Oil Pulling With Clove Oil, Coconut Oil Pulling and Fluoride Mouthwash on Streptococcus Mutans Count in Children
This study aims to compare the effectiveness of coconut oil pulling with clove oil, coconut oil pulling alone, and fluoride mouthwash in reducing Streptococcus mutans levels in children aged 6-12 years.
- Trial name
- COPCO (NCT06902532)
- Testing
- coconut oil pulling with clove oil, coconut oil pulling, Fluoride Mouthwash
- Where
- 2 sites in Egypt
- Volunteers
- 105 people
- Sponsor
- Cairo University
Dental Caries
Performance of GIOMER Based Resin Composite
The aim of the study is to clinically evaluate the performance of GIOMER based resin composite restorations versus conventional nanohybrid resin composite restorations in complex proximal carious cavities in posterior teeth over…
- Trial name
- NCT06021028
- Testing
- complex proximal carious cavities in posterior teeth.
- Where
- Egypt
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Clinical Evaluation of a Self-etch Adhesive Using a Selective Etch Technique
Study hypothesis: Etching the enamel followed by use of a self-etching adhesive on enamel and dentin is as effective as a one-step etch and rinse approach.
- Trial name
- NCT01369134
- Testing
- Adper Easy Bond Self-etch dental adhesive
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Solventum US LLC
Dental Caries
Evaluation of a New Bioactive Material Versus a Fluoride-Releasing Hybrid Restorative Material in Cervical Lesions
This study will be conducted to evaluate and compare the clinical performance of fluoride, calcium, and phosphate-releasing new bioactive material versus a fluoride-releasing hybrid restorative material in cervical lesions for…
- Trial name
- NCT05149209
- Testing
- cervical restoration
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Is Xylitol Toothpaste Effective in Preventing Tooth Decay?
The study will identify children at high caries risk and provide their parents/caregivers with evidence-based, risk-based at-home preventive measures for their infants, including daily use of xylitol or fluoride toothpaste.
- Trial name
- NCT04096599
- Testing
- Xylitol toothpaste, Fluoride toothpaste
- Where
- China
- Volunteers
- 579 people, healthy volunteers welcome
- Sponsor
- Dr. Gillian Lee
Dental Caries Extending Into Dentin
Antibacterial Effect of Light-activated Calcium Silicate Versus Light-activated Calcium Hydroxide
This is a randomized clinical study. 48 subjects with a confirmed diagnosis of deep carious molars without pulpal lesions were randomized to one of two treatments: Patients treated with Light-cured calcium silicate (Theracal)…
- Trial name
- NCT03214770
- Testing
- TheraCal, light-cured calcium hydroxide
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Association Between Primary School Children's Speaking Attitudes and Oral Health Indicators
his cross-sectional study aims to evaluate the relationship between primary school children's speaking attitudes and oral health indicators, including dental caries, malocclusion, and tooth loss.
- Trial name
- NCT07271810
- Testing
- Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Ezgi Turkyilmaz
HIV Infection Primary
Kinetics of HIV-RNA Decay in Seminal Plasma of Men Treated by Dolutegravir at the Time of Primary HIV Infection
Sponsor: IMEA - Fondation Internationale Léon Mba C.H.U. Bichat - Claude Bernard 46, Rue Henri Huchard - 75018 PARIS Tél. : 01.40. 25. 63.
- Trial name
- DOLUPRIM (NCT02976259)
- Testing
- Dolutegravir
- Volunteers
- 20 people
- Sponsor
- Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba
Dental Caries, Endodontically Treated Teeth
Clinical Evaluation of Posterior Indirect Adhesive Restorations
Clinical performance of indirect adhesive restorations - onlays, overlays- luted with light-cured composite resin will be evaluated over three years.
- Conditions
- Dental Caries, Endodontically Treated Teeth, Dental Restoration Failure of Marginal Integrity, Wear, Occlusal
- Trial name
- NCT04293770
- Testing
- Indirect adhesive restoration of posterior teeth
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Okan University
Caries
The Effect of Silver Diamine Fluoride (SDF) on Bacteria Involved in Root or Cervical Carious Lesions
The study will compare bacteria levels in cavities before and after silver diamine fluoride (SDF) treatment.
- Trial name
- NCT02953886
- Testing
- Silver Diamine Fluoride (SDF)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Heba Mitwalli
Caries
Is DIAGNOcam Comparable to Bitewing Radiographs as a Diagnostic Method for Approximal Caries in Primary Teeth?
BACKGROUND: To diagnose caries in clinical practice today, a combination of clinical examination with mirror and probe, and in sometimes x-ray images are used.
- Trial name
- Diagncamera (NCT03181711)
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Malmö University
Early Childhood Caries
Happy Teeth for Hopi Tots: Cultural Adaptation of an Oral Health Entertainment-Education Intervention
Tooth decay is a preventable disease occurring at high rates among American Indian (AI) populations. The use of entertaining educational materials and cultural adaptation have shown success in improving health behaviors.
- Trial name
- NCT05297526
- Testing
- Culturally adapted children's book, Standard informational brochure on children's oral health
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northern Arizona University
Dental Caries, Pulp Disease, Dental
Pulpotomy Versus Pulpectomy in Vital Primary Incisors
The aim of this split mouth randomized controlled study was to compare formocresol pulpotomy and zinc-oxide and eugenol pulpectomy in the treatment of vital pulp exposure in primary incisor.
- Trial name
- NCT05589025
- Testing
- pulpotomy technique with formocresol, pulpectomy technique with zinc oxide and eugenol
- Volunteers
- 39 people
- Sponsor
- National Research Centre, Egypt
Deep Caries
Evaluation of Biodentine Versus Glass Ionomer Cement in Treatment of Very Deep Carious Lesions
The aim of this study is to compare the effect of new bioactive dentine substitute (Biodentine) versus glass ionomer cement in very deep carious lesions clinically and radiographically using digital radiography in the terms of…
- Trial name
- NCT02868918
- Testing
- biodentine, glass ionomer cement, DigoraH optium
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries in Children, Early Childhood Caries
Effect of Optimized Behavioural Intervention Using The Multi-Phase Optimization Strategy (MOST).
In the current study, MOST approach is proposed, to engineer an oral health behavior modification intervention, to increase the engagement of mothers in brushing their pre-school children's teeth.
- Trial name
- NCT04923581
- Testing
- Oral Health Behavioral Interventions
- Where
- 2 sites in Egypt
- Volunteers
- 128 people
- Sponsor
- Merna Ihab
Dental Caries (Diagnosis), Diagnostic Imaging
Diagnostic Performance and Children's Acceptance of Near-Infrared Light Transillumination and Bitewing Radiographs for Detecting Proximal Cavitation in Primary Molars of Patients Aged 4 to 10 Years
The goal of this observational study is to compare the diagnostic performance of three detection methods for approximal carious lesions in primary molars among pediatric patients aged 4-10 years.
- Conditions
- Dental Caries (Diagnosis), Diagnostic Imaging, Optical Imaging, Radiographic Image Interpretation, Computer-Assisted
- Trial name
- NILT (NCT07041164)
- Testing
- Bitewing radiograph, Near-infrared light transillumination
- Where
- 2 sites in Thailand
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Sawanya Prutthithaworn
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.