Clinical trials: Caries, Dental
Dental Caries
Clinical Performance of Bioactive Highly Filled Injectable Flowable Composite for Direct Posterior Occlusal Conservative Restorations Using FDI Criteria: Two Year Randomized Clinical Trial
The aim of this study is to evaluate Clinical Performance of bioactive highly filled injectable flowable composite for direct posterior occlusal conservative restorations using FDI Criteria
- Trial name
- NCT06790511
- Testing
- bioactive highly filled injectable flowable composite, highly filled injectable flowable composite
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Artificial Intellegence
Accuracy of an Artificial Intelligence-assisted Diagnostic System for Caries Diagnosis: a Prospective Multicenter Clinical Study
This clinical trial was designed as a prospective, multicenter, multi-reader multi-case (MRMC), superiority, parallel-controlled study. Participants who met the trial criteria and signed the informed consent form were enrolled.
- Conditions
- Dental Caries, Artificial Intellegence, Diagnosis, Machine Learning
- Trial name
- NCT06428344
- Volunteers
- 220 people
- Sponsor
- Zhejiang Provincial People's Hospital
Dental Caries, Gingivitis
Anticaries Effect of Probiotic Lactobacillus Brevis CD2 (Lb CD2).
In a previous study the efficacy of Lb CD2 on interim covariates related to caries development was tested. So, it was decided to plan a new study on schoolchildren from the same area.
- Trial name
- NCT01778699
- Testing
- lozenges
- Where
- Italy
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Dental Caries, Fissure Sealants
Comparative Evaluation of Glass Ionomer and Resin-Based Fissure Sealants on Newly Erupted Permanent First Molars: A 24-Month Randomized Clinical Trial
This clinical study aims to compare the clinical performance of two different fissure sealant materials-glass ionomer and resin-based-when applied to newly erupted permanent first molars in children.
- Conditions
- Dental Caries, Fissure Sealants, Permanent Molars, Child
- Trial name
- FISSURE24 (NCT07115290)
- Testing
- Glass ionomer-based fissure sealant, Resin-based fissure sealant
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Gulcin Bulut
Caries,Dental, Remineralization
Remineralization Efficacy of Gum Arabic Varnish.
The aim of this study is to evaluate the remineralizing capacity of Gum Arabic varnish and its implementation into clinical practice.
- Conditions
- Caries,Dental, Remineralization, White Spot Lesion
- Trial name
- NCT04422860
- Testing
- Gum Arabic varnish, Proflourid Varnish,VOCO, MI Varnish,GC Japan Inc.
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Fluorosis, Dental Caries
Effect of pH and Fluoride Concentration of Dentifrices on Caries Control
This study aims to assess the overall effect of pH and fluoride concentration of liquid dentifrices in the control of children dental caries of a fluoridated area, through visual inspection and the quantitative light-induced…
- Trial name
- EPHFCDCC (NCT01049503)
- Testing
- Low fluoride and conventional dentifrices with different pH
- Where
- Brazil
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Caries
The Children's Amalgam Trial
The Children's Amalgam Trial is one of only two randomized trials of its kind, and the only such trial in the United States, to address the potential impact of mercury exposure from amalgam restorations on neuropsychological and…
- Trial name
- NCT00065988
- Testing
- Dispersed phase amalgam restoration /composite restoration
- Where
- United States
- Volunteers
- 534 people
- Sponsor
- Carelon Research
Caries, Dental
Effect of Pulpotomy Using TheraCal Versus MTA on Survival Rate of Cariously-Exposed Vital Permanent Molars
Objective: To assess which is the most efficient pulpotomy medicament on tooth survival in patients with a cariously-exposed vital young permanent molar regarding: absence of postoperative pain, sinus or swelling, internal/…
- Trial name
- NCT03119779
- Testing
- MTA-Anglus, TheraCal
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Deep Caries
Multicenter Trial Comparing One-step Partial Caries Removal to Complete Caries Removal for the Treatment of Deep Carious Lesions in Permanent Teeth. (DECAT : DEep CAries Treatment).
This clinical trial is a national multicenter randomized controlled trial performed in parallel groups aiming to validate a treatment that preserves pulp vitality of mature permanent posterior teeth through partial removal of…
- Trial name
- DECAT (NCT02286388)
- Testing
- A one-step partial caries removal procedure for the treatment of deep carious lesions in posterior permanent teeth., A complete caries removal procedure for the treatment of deep carious lesions in posterior permanent teeth., The application of an antibacterial dental adhesive (ClearfilTM SE Protect, Kuraray Dental).
- Where
- 15 sites in France
- Volunteers
- 464 people
- Sponsor
- Hospices Civils de Lyon
Healthy Participants
The Effect of Daily Brief Heat Exposures on Heat Acclimation
This study is the first to examine the effects of short passive heat exposure on heat acclimation (HA). Unlike traditional protocols requiring prolonged heat exposure, this study tests whether a daily 5-minute whole-body…
- Trial name
- NCT07198334
- Testing
- Heat acclimation
- Where
- Lithuania
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Neurocognitive Deficit, Quality of Life
WHOle Brain Irradiation or STEreotactic Radiosurgery for Five or More Brain Metastases (WHOBI-STER)
This work aims to evaluate neurocognitive performance, daily activity and quality of life and local control among patients with brain metastasis (MBM) ≥ 5 due to solid tumors treated with Stereotactic RadioSurgery (SRS) or Whole…
- Conditions
- Neurocognitive Deficit, Quality of Life, Activities of Daily Living
- Trial name
- WHOBI-STER (NCT04891471)
- Testing
- Stereotactic RadioTherapy, Whole Brain Irradiation
- Where
- 4 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Mediterranean Institute of Oncology
Dental Caries
Properties of Glass Ionomer Cements Associated With Chlorhexidine or Doxycycline
This study assessed the clinical performance of a resin-modified glass ionomer cement containing different concentrations of chlorhexidine digluconate and doxycycline hyclate.
- Trial name
- NCT02168374
- Testing
- Indirect pulp treatment
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Aline R F de Castilho
Type 2 Diabetes, Obesity & Overweight
Effects of GLP-1 Receptor Agonists on Saliva and Oral Health
This study aims to evaluate the effects of GLP-1 receptor agonists (GLP-1RA) on salivary parameters and oral health in individuals who will use this medication for the first time due to a diagnosis of Type 2 diabetes and/or…
- Conditions
- Type 2 Diabetes, Obesity & Overweight, Xerostomia, Dental Caries
- Trial name
- NCT07818226
- Testing
- GLP-1 Receptor Agonists
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kırıkkale University
Root Caries
Silver Diamine Fluoride Application on Root Caries Fillings
The goal of this clinical trial is to learn the influence of prior silver diamine fluoride (SDF) application on root caries fillings. The main questions to answer 1.
- Trial name
- NCT06514885
- Testing
- SDF solution application, Tonic water
- Where
- Hong Kong
- Volunteers
- 184 people
- Sponsor
- The University of Hong Kong
Educational and Preventive Session for Dental Caries, Oral Diseases
Oral Health Promotion Program in Schools in Polígono Sur
The objective of this observational study is to evaluate oral health before and after conducting an educational session on oral hygiene in schoolchildren from 3 schools in the Polígono Sur of Seville.
- Trial name
- OHPPSPS (NCT06797778)
- Where
- Spain
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- University of Seville
Dental Caries, Crowned Posterior Teeth
Hall Technique vs Conventional Technique in Permanent Teeth
The purpose of this study is to evaluate and compare the clinical and radiological performance of stainless steel crowns using conventional and Hall technique on permanent molars
- Trial name
- NCT07100028
- Testing
- SSC crown with Hall technique, SSC with conventional technique
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries
Comparative Effectiveness of Treatments to Prevent Dental Caries
Dental caries (tooth decay) is the most prevalent childhood disease in the world. Multiple interventions are available to treat and prevent caries.
- Trial name
- NCT03448107
- Testing
- Silver Diamine Fluoride, Fluoride Varnishes, Glass Ionomer
- Where
- United States
- Volunteers
- 3,345 people, healthy volunteers welcome
- Sponsor
- NYU College of Dentistry
Dental Caries
Teledentistry Mobile Photos Versus Conventional Clinical Examination for Dental Caries Diagnosis
Teledentistry is an intervention that can boost chances for the new primary healthcare paradigm, bringing service delivery and accessibility to new levels.
- Trial name
- NCT06661837
- Testing
- Clinical examination and mobile photo
- Where
- Egypt
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Healozone Study to Evaluate the Safety and Efficacy of the Use of Ozone for Management of Dental Caries
Caries means demineralization with the formation of cavities and pulp symptoms and necrosis as an end result. The acids in the mouth are mainly produced by oral bacteria like Streptococcus mutans from bacterial biofilms adhering…
- Trial name
- NCT00495495
- Testing
- Ozone treatment
- Where
- 3 sites in United States
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- Indiana University
Dental Caries
Glass-ionomer Cement Containing Chlorhexidine for ART
This study evaluated the clinical and microbiological long-term effects of 1.25% CHX associated with GIC applied in primary molars using Atraumatic Restorative Treatment (ART) technique.
- Trial name
- NCT02459730
- Testing
- ART with GIC containing 1.25% CHX., ART with GIC.
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
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