Clinical trials: Caries, Dental
Caries,Dental, Deep Caries
Comparative Evaluation of an Electrical Impedance Device Versus Digital Radiography in Estimation of Remaining Dentin Thickness
The research question was that in patients with carious posterior permanent teeth, would the electrical impedance device be as valid as digital radiography in estimation of remaining dentin thickness? The proposed hypothesis was…
- Trial name
- NCT06162182
- Testing
- electrical impedance device,, Reference test: Digital Radiographic examination
- Where
- 2 sites in Egypt
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Rawda Hesham Abd ElAziz
Amelogenesis Imperfecta, Dental Caries
Clinical Performance of Composites in Patients With Amelogenesis Imperfecta
In AI patients, adhesion still remains the first option in order to achieve an early, minimally invasive intervention, and the altered enamel still represents an acceptable substrate for bonding in some AI variants.
- Conditions
- Amelogenesis Imperfecta, Dental Caries, Dental Composite
- Trial name
- NCT04897724
- Testing
- dental composite
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Neslihan Tekçe
Caries; Dentin
SMART With Different Modifications in Asymptomatic Deep Carious Lesions of Primary Molars.
This study aimed to evaluate the clinical success of the 'Silver Modified Atraumatic Restorative Technique '(SMART) with different modifications in asymptomatic deep carious lesions of primary molars.
- Trial name
- NCT06645860
- Testing
- SDF+KI+LED Light 20s, SDF+KI
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Dental Caries in Children
Application of SDF Verses NaF Varnish in Treatment of Carious Primary Teeth
The aim of this study is to assess the postoperative pain after application of silver diamine fluoride versus sodium fluoride varnish in treatment of carious primary teeth.
- Trial name
- NCT03554980
- Testing
- Silver Diamine Fluoride, Sodium Fluoride varnish
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries,Dental
Caries-associated Saliva Biomarkers Among Different Races
discover possible differences and develop effective preventative interventions by examining the relationship between salivary biomarkers and caries prevalence across different racial groups and Detect risk factors involved in…
- Trial name
- NCT06838182
- Testing
- Salivary biomarkers tests
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries,Dental
Effect of Er,Cr:YSGG Sub-Ablative Laser Irradiation on Fissure Caries Prevention in Permanent Molars
Background: Subjecting human dental enamel to sub-ablative laser has been suggested as a novel way of caries prevention. However, further studies are needed to establish its use as a routine clinical procedure for caries…
- Trial name
- NCT06826456
- Testing
- sub-ablative Er,Cr:YSGG laser, Fluoride varnish application
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Carious Lesion
Silver Diamine Flouride in Arresting Enamel Caries
This interventional study aims to evaluate the effectiveness of 38% Silver Diamine Fluoride (SDF) in arresting enamel caries in adults aged 18-50 years.
- Trial name
- NCT07125937
- Testing
- 38% Silver Diamine Fluoride
- Where
- Pakistan
- Volunteers
- 250 people
- Sponsor
- HITEC-Institute of Medical Sciences
Caries, Dental, Pulpitis
Indirect Pulp Capping With Resin Modified Glass Ionomer
In deep carious lesions, presenting risk of pulp exposition, a treatment option is the partial caries removal of carious tissue followed by provisional restoration, while this approach is called indirect pulp capping.
- Trial name
- NCT02494193
- Testing
- Partial caries removal, Provisional restoration - control, Provisional restoration - experimental
- Where
- Brazil
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Oral Findings in Children of Multiple and Single Births, Radiographic Evaluation of Oral Findings in Children of Multiple and Single Births
Clinical and Radiographic Evaluation of Oral Findings in Children of Multiple and Single Births
Clinical and radiographic evaluation of oral findings in children of multiple and single births
- Trial name
- NCT04697017
- Testing
- The contribution of genetics to dental caries, oral habits and occlusal traits in children of multiple births
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 690 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Pulmonary Diseases, Tonsillar Hypertrophy
The Influence of Feeding Position on Pulmonary Morbidity in Young Children
Supine feeding position is associated with serous otitis media. The hypothesis is that supine feeding is associated with recurrent otitis media, tonsillar and adenoid hypertrophy and recurrent pneumonia secondary to recurrent…
- Conditions
- Pulmonary Diseases, Tonsillar Hypertrophy, Otitis Media, Dental Caries
- Trial name
- NCT00248391
- Testing
- upright feeding
- Where
- Israel
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Dental Caries, Reversible Pulpitis
The CAP-1 Trial: Stepwise Excavation Versus One Completed Excavation in Deep Caries
Brief summary Background: A large proportion of dental practice involves the treatment of caries in the permanent dentition. In USA alone tooth related pain is annually responsible for 15 billions days lost through sickness.
- Trial name
- NCT00187837
- Testing
- SW, DCE
- Where
- Denmark
- Volunteers
- 314 people
- Sponsor
- University of Copenhagen
Oral Diseases
Carnosine Supplementation on Quantity/Quality of Oral Salivae.
The aim of this study is to elucidate the mutual relationship between salivae characteristics and oral microbiome and to compare them with common oral disease; furthermore, by using specific bioinformatic tools to analyse the…
- Trial name
- PHoral (NCT04295525)
- Testing
- 400 mg mucoadhesive oral tablet
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Milan
Dental Caries
Effectiveness of SDF With Different Post-treatment Protocols in Arresting Dental Caries
To compare the effectiveness of the semi-annual application of 38% SDF with two post-treatment protocols in arresting dental caries in preschool children
- Trial name
- NCT05655286
- Testing
- 38% SDF treatment, not to rinse for at least 30 minutes after SDF treatment, rinse mouth immediately after SDF treatment
- Where
- China
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Decay, Dental, Impacted Third Molar Tooth
Risk Factors for Distal Caries of Second Molars Adjacent to Mandibular Impacted Third Molars
Distal surfaces of second molars adjacent to wisdom teeth are always at risk for caries and external root resorption. The incidence of caries is high, especially in partially impacted third molars in mesioangular and horizontal…
- Trial name
- NCT06017570
- Testing
- Radiologic examination on orthopantomogram, Clinical examination after surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 639 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Dental Caries, Periodontal Diseases
Biomimetic Hydroxyapatite in Pediatric Patients With Asthma and/or Allergic Rhinitis
The aim of the study is to compare the incidence of dental caries and the level of demineralization in pediatric patients with asthma and/or allergic rhinitis. Patients will conduct professional oral hygiene at the baseline.
- Trial name
- NCT05631197
- Testing
- Biorepair Total Protection Plus + desensitizing enamel-repair shock treatment, Sensodyne Repair & Protect
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Periodontal Diseases, Caries Dentalis
Dental and Periodontal Health Levels of Dental and Medical Faculty Students
The aim of this observational study is to investigate the relationship between periodontal and dental health status and oral health-related quality of life among dental and medical faculty students.
- Trial name
- NCT07425860
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Severe Early Childhood Caries, Dental Caries
Salivary Antimicrobial Peptides and Severe Early Childhood Caries in Turkish Children
This observational study aims to evaluate the relationship between salivary antimicrobial peptides and severe early childhood caries (S-ECC) in Turkish children.
- Trial name
- NCT07414030
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Caries Arrested
Selective Versus Stepwise Removal of Deep Carious Lesions in Permanent Teeth Using Different Medicaments
The study involved 54 adult patients between the ages of 18 and 50 years who had a posterior permanent tooth with a deep occlusal (Class I) carious lesion that extended to the inner third of the dentin (D3) and divided them into…
- Trial name
- NCT06585436
- Testing
- partial caries removal
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries
Is Xylitol Toothpaste Effective in Preventing Tooth Decay?
The study will identify children at high caries risk and provide their parents/caregivers with evidence-based, risk-based at-home preventive measures for their infants, including daily use of xylitol or fluoride toothpaste.
- Trial name
- NCT04096599
- Testing
- Xylitol toothpaste, Fluoride toothpaste
- Where
- China
- Volunteers
- 579 people, healthy volunteers welcome
- Sponsor
- Dr. Gillian Lee
Caries,Dental
Microbial Sampling of Carious Dentin
The School of Dentistry is seeking to determine whether viable microorganisms remain within tooth structure after conventional, mechanical removal of areas of tooth decay, prior to placement or replacement of tooth restorations…
- Trial name
- NCT04011605
- Testing
- Biological Sample of Carious Dentin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Utah
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