Clinical trials: Caries,Dental
HIV Infections
A Study to Compare the Effectiveness of a Four Drug Anti-HIV Regimen Given Alone or in Combination With GM-CSF or IL-12 to HIV-Positive Patients
The purpose of this study is to examine how the level of HIV is reduced in the blood when anti-HIV therapy is initiated. This study will also evaluate whether adding GM-CSF or IL-12 to the anti-HIV drug regimen will increase the…
- Trial name
- NCT00000896
- Testing
- Indinavir sulfate, Lamivudine/Zidovudine, Hepatitis A Vaccine (Inactivated)
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Dental Caries, Prevention
Sealant Application by Interns After Tele-demonstration
Abstract Background: Dental caries remains a major public health issue worldwide, particularly among children. Pit and fissure sealants represent a high-quality, evidence-based preventive measure.
- Conditions
- Dental Caries, Prevention, Education
- Trial name
- TESS (NCT07232797)
- Testing
- tele-demonstration, traditional demonstration group
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries
Randomized Clinical Trial of Occlusal Sealant
This study assessed long-term impact of tooth Eruption Stages (ES) on sealant retention on occlusal surfaces previously coated with intermediary bonding layer and it determined caries incidence outcome evolved.
- Trial name
- NCT02589743
- Testing
- Sealant, Adhesive and Sealant
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Dentin Hypersensitivity
Effect of Gluma and Bioactive Glass Desensitizers in Treatment of Dentin Hypersensitivity in Cervical Non-Carious Lesions
Type of study: (A Randomized Controlled Clinical Trial) Aim :The aim of this randomized controlled clinical trial is to evaluate the effect of Gluma, Bioactive Glass and combination of both, compared to Flouride Varnish on the…
- Trial name
- NCT07063433
- Testing
- Gluma Desensitizer, Bioactive glass, Fluoride varnish
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- British University In Egypt
Dental Caries
Trial of a New NuSmile ZR Esthetic Primary Molar Crown
The hypothesis to be tested is that NuSmile ZR esthetic primary molar crowns perform similarly to an established Stainless Steel primary molar crown (3M ESPE) for restoration of primary molar teeth.
- Trial name
- NCT01919515
- Testing
- ZR Crown, Stainless Steel Crown
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- NuSmile, Ltd.
Dental Caries
Miswak Versus Standard Measures to Prevent the Incidence of Caries Young Egyptian Adults: A Randomized Controlled Clinical Trial
Objectives: Aim of the study The objective is to conduct an RCT to evaluate the effectiveness of miswak in comparison with standard caries preventive measures for the prevention of new carious lesions in high caries risk…
- Trial name
- NCT03732040
- Testing
- miswak stick, Miswak plus tooth brushing and tooth paste, Standard preventive measures (tooth brushing , interdental cleaning and mouth rinse use containing CHX and Fluoride)
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Adhesion
Efficiency of Different Modes of Universal Adhesive
The purpose of this study is to evaluate and compare the clinical performance of a Universal adhesive's different application modes.
- Trial name
- NCT04271150
- Testing
- Self-etch, Total-etch
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Post Dental Restoration, Caries, Dental
Clinical Performance of Two Bulk-Fill Composite of Posterior Restorations
To minimize the effects of polymerization shrinkage in the restorative treatment, there are new composites called Bulk- Fill which the companies has developed this composites for example Tetric N Ceram(Ivoclar-Vivadent) and…
- Trial name
- NCT03230604
- Testing
- Filtek Bulk Fill Composite and Tetric N Ceram Bulk Fill Composite, Z 350 Xt Composite
- Where
- Chile
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Andres Bello
Pulpitis, Pain Management
Effects of Topical Anesthesia Approaches on Dental Pain During and After Restorative Management of Dental Caries
The purpose of the Research Study and Overview of Participation: This study will compare different approaches used to prevent pain when giving local anesthesia to numb the teeth while managing dental cavities and decay.
- Trial name
- NCT07379515
- Testing
- Photobiomodulation (PBM)-induced analgesia device using multi-wavelength LED, Medicated analgesia
- Volunteers
- 204 people
- Sponsor
- Dubai Health
Dental Caries in Children
Evaluation of Children's Oral Health Education With Different Education Methods
Different educational methods may play a crucial role in oral and dental health education programs. The aim of our study is to evaluate the effects of different educational methods on the knowledge levels of primary school…
- Trial name
- NCT06569745
- Testing
- Verbal Explanation, Animation Video Display, Peer-Led Reels Video Display
- Where
- Turkey (Türkiye)
- Volunteers
- 464 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Dental Caries in Children
Comparing the Effectiveness of Papain Based Chemico-mechanical Caries Removal Gel and 38% Silver Diamine Fluoride for Treating Active Caries Lesion of Primary Molars
This study aims to investigate the efficacy of silver diamine fluoride (SDF) and Papain-based chemico-mechanical caries removal gel and using ceramic bur as a control in treating dentine caries in primary molars aged 7-8 years…
- Trial name
- NCT06412731
- Testing
- Cera-bur, Brix3000, E-SDF
- Where
- Iraq
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Dental Caries, Caries,Dental
Caries Prevalence, Experience and Risk Related Factors Among Early Middle-aged Patients Attending Cairo University
Dental caries, a widespread oral health issue, results from a complex interplay of factors including behavior, hygiene, diet, and socio-demographic aspects.
- Trial name
- NCT06365281
- Where
- Egypt
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Cairo University
Poor Aesthetic of Existing Restoration of Tooth, Dental Restoration Failure of Marginal Integrity
The Effect of Different Adhesion Strategies on the Clinical Success
The study will involve 41 people who regularly seek treatment at clinics. Participants must be in generally good health and be older than eighteen.
- Conditions
- Poor Aesthetic of Existing Restoration of Tooth, Dental Restoration Failure of Marginal Integrity, Unacceptable Morphology of Tooth Restoration, Secondary Caries
- Trial name
- NCT06500546
- Testing
- Treatment of cervical lesions
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Dental Caries, Obesity Prevention
Advancing Water Security: A Community Participatory School-Based Hydration Intervention
The goal of this study is to determine the effectiveness and sustainability of a community-participatory hydration intervention over 3 years within a district that has newly installed hydration stations and is operating under a…
- Trial name
- NCT06714929
- Testing
- Hydration
- Where
- United States
- Volunteers
- 7,200 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Secondary Caries, Dental Restoration Failure of Marginal Integrity
Comparative Evaluation of Class V Restorations
To evaluate and compare the 2-year clinical performance of Class V restorations using various restorative systems with ion-releasing and non-ion-releasing composites, utilizing fluoride-free and fluoride-releasing universal…
- Trial name
- NCT06164418
- Testing
- Dental restoration
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Caries, Dental
The Effects of Stainless Steel Crowns Applied With Hall Technique on Occlusal Vertical Dimension
In recent years restoring carious of fractured primary teeth with stainless steel crowns (SSC) has became more popular than ever.
- Trial name
- NCT03010618
- Testing
- Hall technique stainless steel crowns
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Root Caries
Evaluation of Corrective Surgery Versus Dental Implants in Compromised Upper Molars
This study seeks to assess the clinical, radiographic, and patient-reported outcomes of root amputation versus implant over a 12 months period, generating robust evidence to guide clinical decision-making and enhance patient care.
- Trial name
- NCT07608497
- Testing
- root amputation
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Inflammatory Bowel Diseases, Periodontitis
Oral Health-related Quality of Life (OHRQoL) in Patients With Inflammatory Bowel Disease (IBD)
IBD patients have a higher risk of oral diseases that affect the oral mucosa, the teeth and the tooth supporting tissues. These conditions are often associated with pain, bleeding and impaired masticatory function which may have…
- Conditions
- Inflammatory Bowel Diseases, Periodontitis, Dental Caries, Tooth Loss
- Trial name
- OQal-MICI (NCT05096897)
- Testing
- Self-administrated questionnaires
- Where
- France
- Volunteers
- 138 people
- Sponsor
- University Hospital, Lille
Unsatisfactory Restoration of Tooth, Carious Teeth
Biological and Esthetic Evaluation of Ceramic Onlay With Different Preparation Designs
Aim of study: is to asses biological and esthetical success of ceramic onlay restorations while preparing the teeth using shoulder finish line preparation versus butt joint with bevel preparation.
- Trial name
- NCT04438642
- Testing
- shoulder finishline, butt joint with bevel
- Where
- Egypt
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Ahmed Adel Mahmoud Gadallah
Restored Decayed Teeth and Post-operative Sensitivity
Dental Cement in Post-operative Sensitivity: Randomized Clinical Trial
Context: CEMENT PBS CIMMO DTA® has physical and biological properties that classify it as a biocompatible material and inducer of biomineralization, attributes that qualify it as material as an indirect pulp capper in permanent…
- Trial name
- Bioactivity (NCT04870294)
- Testing
- Teeth treated with composite resin, control group, Teeth treated with lining, pulp wall with PBS DTA® cement and composite resin restoration
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai