Clinical trials: Caries,Dental
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Remineralization of White Spot Lesions Using Self-Assembling Peptide P11-4 in Primary Anterior Teeth A Randomized Clinical Trial
This study is a randomized controlled clinical trial on primary anterior teeth of 3-5 year-old patients suffering from white spot lesions (ICDAS system II scores 1-2).
- Trial name
- NCT03927794
- Testing
- Self-Assembling Peptide P11-4
- Where
- Egypt
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries
Development and Validation of a Multi-Mineral Fluoride Mouthrinse
The primary goals of this project are to determine the anticaries benefits of a prototype multi-mineral mouthrinse containing 225 ppm fluoride and 30 ppm of a Ca through the remineralization of enamel white-spots (non-cavitated…
- Trial name
- NCT00642252
- Testing
- Fluoride
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana Nanotech, LLC
Dental Caries Extending Into Dentin
Comparison of Conventional Versus Conservative Caries Removal in Primary Teeth
The sample will be, at least, 90 primary molars, randomly distributed into three groups: Group 1: IPC; Group 2: SE; Group 3: SCR.
- Trial name
- Caries_removal (NCT03650647)
- Testing
- Carious dentin removal
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Femoral Neck Fractures, Pertrochanteric Fracture
Bone Intake Proteins and Muscle Mass Deficiency in Proximal Femur Fractures
The aim of this clinical trial is to compare serum concentration of bone intake proteins [ sex hormone-binding globulin (SHBG), cross linked C-telopeptide of type I collagen (CTX-I)] and muscle atrophy marker [creatine kinase…
- Conditions
- Femoral Neck Fractures, Pertrochanteric Fracture, Bone Resorption, Bone Loss
- Trial name
- NCT05804604
- Testing
- Surgical treatment of proximal femur fracture and blood sample test, Blood sample test
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Tooth Decay
Clinical Assessement of Glazed Versus Polished Lithium Disilicate Crowns in Surface Roughness and Enamel Antagonists Wear
It is believed that final glazing yields the most acceptable ceramic surfaces in terms of smoothness. However, since reglazing must be performed in a dental laboratory with the use of a thermal furnace, it requires multiple…
- Trial name
- NCT03696849
- Testing
- polished emax Press
- Volunteers
- 28 people
- Sponsor
- Cairo University
Dental Anxiety, Children, Only
Effect of Parental Absence on Child's Dental Anxiety and Behaviors During Dental Treatment
The basis of pediatric dentistry is to provide cooperation in children with various behavioral management techniques. The presence or absence of the parent during dental treatments can be used to ensure the child's compliance…
- Conditions
- Dental Anxiety, Children, Only, Dental Caries
- Trial name
- NCT05125731
- Testing
- Parental absence, Parental visual support, Parental presence
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Acute HIV Infection
Effects of Intensive cART During Acute/Early HIV Infection
This trial will investigate the efficacy and safety of intensified antiretroviral treatment that includes raltegravir and maraviroc during the early stages of HIV infection.
- Trial name
- NCT01154673
- Testing
- raltegravir, maraviroc, emtricitabine 200mg /tenofovir 300mg
- Where
- 2 sites in Canada
- Volunteers
- 32 people
- Sponsor
- University of Toronto
Caries
Clinical Evaluation of SI-R21204 Versus Nano-hybrid Resin Composite: A Prospective Controlled Clinical Trial
Despite the advances in adhesive restorative techniques and materials, dental caries still remains a critical concern even today.
- Trial name
- NCT02823769
- Testing
- SI-R21204 resin composite, Nanohybrid resin composite
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Dental Caries, Dental Adhesive Materials
Clinical Performance of Bioactive Restorative Materials
The aim of this clinical study is to evaluate the performance of three different bioactive restorative materials against a composite resin for a period of 9 months.
- Trial name
- Bioactive (NCT07394751)
- Testing
- Tetric N Ceram Bulkfill application, Cention Forte application, Stela Automix
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ege University
Obesity, Dental Caries
Nutrition Knowledge for Spanish-speaking Parents
Providing child nutrition information is a major goal of every pediatric well-child visit. Unfortunately, due to a wide array of issues, doing this effectively during clinic visits is challenging and insufficient.
- Trial name
- NCT01296945
- Testing
- Kiosk, paper, Kiosk PLUS paper
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Caries,Dental
CARDEC-PEL: Comparison of Two Methods of Caries Risk Assessment in Children
The aim of the study was to compare dental caries treatment and follow-up based on an elaborate and individualized assessment of caries risk in children, to a simpler risk assessment strategy by means of a double-blind randomized…
- Trial name
- NCT03969628
- Testing
- ICCMS
- Where
- Brazil
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Dental Caries
Building Adaptive School-based Interventions for Caries
Dental caries (tooth decay) is the world's most prevalent noncommunicable disease. Current preventive and therapeutic treatments are available that can be provided in a school-based health service environment.
- Trial name
- BASICS (NCT07265830)
- Testing
- Silver Diamine Fluoride (38%), Glass Ionomer Sealant, Fluoride Varnishes
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Tooth Decay, Missing Tooth/Teeth
Correlation Study Between Socio-economical Deprivation and Oral Health in Children of 9 Years of Age
Retrospective, observational cohort study. Objectives : To search for correlations between socio-economical deprivation and oral health in french children of 9 years of age.
- Trial name
- PRECA-6 (NCT03817437)
- Where
- France
- Volunteers
- 600,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Dental Caries, Child Behavior
Efficacy of Moderate Sedation for Dental Treatment of Young Children
There is lack of clinical trials on pediatric dental sedation. The purpose of this study is to test (using a randomized controlled trial design) the hypothesis that young children behavior during dental treatment improves with…
- Conditions
- Dental Caries, Child Behavior, Conscious Sedation Failure During Procedure
- Trial name
- NCT00902395
- Testing
- Midazolam, Protective stabilization, Midazolam, ketamine
- Where
- Brazil
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Dental Caries
Decision Aids for the Management of Suspicious Occlusal Caries Lesions
The study will determine whether clinicians who use a diagnostic device treat suspicious occlusal carious lesions (SOCL) surgically more often, with the same frequency, or less frequently, than dentists not relying on a…
- Trial name
- SOCL (NCT02340767)
- Testing
- Spectra Device, DIAGNOdent
- Where
- 6 sites in United States
- Volunteers
- 3,085 people, healthy volunteers welcome
- Sponsor
- The National Dental Practice-Based Research Network
Caries, Dental
Effectiveness of Pit and Fissure Sealants in the Prevention of Dental Caries
This randomized clinical trial is aimed at testing the efficacy of pit and fissure sealants, in a current environmental context different from that of the seventies and eighties. It has a split mouth design.
- Trial name
- NCT00674869
- Testing
- pit and fissure sealant
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Dental Caries
Cost-efficacy Between ART and Composite Resin Restorations in Primary Molars
The aim of this randomized clinical trial study is to compare the longevity of Atraumatic Restorative Treatment (ART) using high viscosity GIC and Conventional Treatment using composite resin under rubber dam isolation and local…
- Trial name
- NCT02562456
- Testing
- ART using Fuji IX, Conventional Treatment
- Where
- Brazil
- Volunteers
- 428 people
- Sponsor
- University of Sao Paulo
Deep Caries
Evaluation of Biodentine Versus Glass Ionomer Cement in Treatment of Very Deep Carious Lesions
The aim of this study is to compare the effect of new bioactive dentine substitute (Biodentine) versus glass ionomer cement in very deep carious lesions clinically and radiographically using digital radiography in the terms of…
- Trial name
- NCT02868918
- Testing
- biodentine, glass ionomer cement, DigoraH optium
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Testing a Tooth Decay Prevention Program With Cree Mothers and Infants
Dental decay is an alarming problem in Cree children. The intervention is a behavioural counseling approach called Motivational Interviewing (MI).
- Trial name
- NCT00175318
- Testing
- Motivational Interviewing
- Where
- Canada
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hiv
Impact of CMV Status on HIV Viral Load Decay
Background: Cytomegalovirus (CMV) infection is usually observed among patients with HIV infection. No study to date has investigated the impact of CMV infection on HIV viral load decay during antiretroviral therapy.
- Trial name
- NCT03349359
- Testing
- HIV antiretroviral therapy
- Where
- France
- Volunteers
- 345 people
- Sponsor
- Hospices Civils de Lyon