Clinical trials: Caries; Dentin
Dental Caries, Composite Resins
Clinical Evaluation of Dentin Replacement Materials in Posterior Composite Restorations
This randomized controlled clinical trial is designed to clinically evaluate and compare the performance of five dentin replacement materials used beneath posterior composite restorations.
- Conditions
- Dental Caries, Composite Resins, Composite Restoration
- Trial name
- NCT07762651
- Testing
- Biodentine, ACTIVA BioACTIVE, glass ionomer cement
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Pulpitis, Caries; Dentin
The Effect of Cryotherapy on the Outcome of Pulpotomy and Root Canal Treatment
The goal of this randomized clinical trial is to compare the outcome of total amputation and root canal treatment with or without cryotherapy in terms of postoperative pain, quality of life, and treatment success for the…
- Conditions
- Pulpitis, Caries; Dentin, Pain, Postoperative
- Trial name
- NCT06183021
- Testing
- Vital pulp cryotherapy, Intracanal cryotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people
- Sponsor
- Ondokuz Mayıs University
Caries,Dental
Microbial Sampling of Carious Dentin
The School of Dentistry is seeking to determine whether viable microorganisms remain within tooth structure after conventional, mechanical removal of areas of tooth decay, prior to placement or replacement of tooth restorations…
- Trial name
- NCT04011605
- Testing
- Biological Sample of Carious Dentin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Utah
Deep Dentin Caries in Primary Teeth, Pulp Therapy in Primary Molars
Indirect and Direct Pulp Therapy in Primary Second Molars
The purpose of this randomized controlled clinical trial was to compare the clinical and radiographic outcomes of indirect pulp treatment (IPT) and direct pulp capping (DPC) using mineral trioxide aggregate (MTA) in deep carious…
- Trial name
- NCT07382115
- Testing
- Indirect Pulp Treatment, Direct Pulp Capping
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara University
Dentin Hypersensitivity, Active Dental Caries
Fluoride Therapies on Hypersensitive Carious Lesions in Primary Teeth
This observational cohort study aims to evaluate the short-term (3 months) efficacy of the standard fluoride therapy in the German National Health System for managing hypersensitive carious lesions in primary teeth (fluoride…
- Trial name
- NCT04804423
- Testing
- 38% Silver Fluoride and Potassium Iodide solution (generic name; Riva Star®), Sodium fluoride varnish (generic name; Duraphat®)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Medicine Greifswald
Irreversible Pulpitis, Reversible Pulpitis
Treatment of Deep Carious Lesions With Selective Caries Removal, Partial or Full Pulpotomy
The optimal treatment of deep caries lesions extended to the inner third of dentin is still under discussion. Cariologists prefer selective caries removal, meanwhile endodontists recommend partial pulpotomy.
- Conditions
- Irreversible Pulpitis, Reversible Pulpitis, Dentine Caries
- Trial name
- Vitapulp (NCT04807244)
- Testing
- Selective Caries Removal with Biodentine™, Partial Pulpotomy with Biodentine™, Full Pulpotomy with Biodentine™
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Caries Active, Dentin, Carious
Success of Zirconia and Stainless Steel Crowns for Permanent Molars
The purpose of this study is to evaluate and compare the clinical and radiographic performance of zirconia and stainless steel crowns on permanent molar
- Trial name
- NCT05049694
- Testing
- zirconia crowns, stainless steel crowns
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dentin Caries, Infection
Microbiological and Microscopic Evaluation of Atraumatic Restorative Treatment in Adult Dentition
Atraumatic Restorative Treatment (ART) was proposed as a new and effective method in the 1990s to provide conservative dental treatment to the people living in economically underdeveloped countries, due to lack of dental…
- Trial name
- NCT04813744
- Testing
- Atraumatic restorative treatment
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Caries; Dentin, Dental Caries
Clinical Performance of Restorative Materials in Primary Teeth
The purpose of this study is to evaluate and compare the clinical performance of dental restorative materials in Class II cavities of primary molar teeth
- Trial name
- NCT03037814
- Testing
- Compomer, RMGIC, Giomer
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Deep Dentin Caries in Mature Permanent Teeth
Partial Pulpotomy vs Selective Removing in Deep Caries
The aim of this study was to compare the one-year results of selective caries removal and partial pulpotomy treatments in terms of pulp survival and the need for further endodontic treatment in deep carious lesions.Individuals…
- Trial name
- NCT07120009
- Testing
- selective caries removal, partial pulpotpmy
- Volunteers
- 70 people
- Sponsor
- Cukurova University
Post-operative Sensitivity, Dentin Hypersensitivity
Gluma Compared With Bonding Agent for Post-operative Sensitivity Following Composite Restorations
The aim of this study is to compare the effectiveness of Gluma desensitizer in reducing post-operative sensitivity following composite restorations in posterior teeth.
- Conditions
- Post-operative Sensitivity, Dentin Hypersensitivity, Dental Caries, Tooth Sensitivity After Composite Restorations
- Trial name
- NCT07188142
- Testing
- Drug/Agent: Gluma Desensitizer, Drug/Agent: No desensitizer (Control)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Beenish Hassan
Class II Dental Caries, Sensitivity, Tooth
Post-operative Sensitivity in Composite Restorations
Participants will be divided into groups. In group A, Composite restoration done using oblique incremental technique. In group B, Bulk-fill technique was used.
- Trial name
- NCT06092567
- Testing
- Group A ( Oblique Incremental Placement Technique), Group B (Bulk-fill Placement technique)
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Early Childhood Caries, Dental Caries in Children
Treatment of Early Childhood Caries Using Silver Diammine Fluoride and Sodium Fluoride Tricalciumphosphate and the Effects on Oral Health Related Quality of Life
There is still a need for the assessment of different minimal intervention strategies and treatments focusing on the prevention and arrest of carious lesions of primary molars The evidence-based clinical practice guideline on…
- Conditions
- Early Childhood Caries, Dental Caries in Children, Dental Caries Extending Into Dentin, Dental Caries
- Trial name
- NCT05772039
- Testing
- Topical application of 38% Silver Diammine Fluoride Solution, Topical application of 5% Sodium Fluoride with functional Tricalcium phosphate Varnish
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Universiti Sains Malaysia
Caries, Salivary Function
Lesion Progression After Icon Treatment in Young Adults
This is a three year single site clinical evaluation of a FDA approved (510(k):K100062) lesion penetrating resin used to infiltrate and hamper progression of proximal carious lesions.
- Conditions
- Caries, Salivary Function, Tooth Sensitivity
- Trial name
- NCT01988337
- Testing
- Resin infiltration, Mock treatment
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- DMG Dental Material Gesellschaft mbH
Dentin Caries
Evaluation of ART Restorations Using Two Different Bulk-Fill Restorative Materials in Primary Molars
The aim of this clinical study is to evaluate the success of two different bulk-fill restorative materials applied to teeth restored with atraumatic treatment at 3, 6, and 12-month follow-ups.
- Trial name
- NCT06771362
- Testing
- ART with Bulk-Fill composite, ART with Glass Ionomer
- Where
- Turkey (Türkiye)
- Volunteers
- 127 people
- Sponsor
- Çanakkale Onsekiz Mart University
Early Childhood Caries (ECC), Active Dentin Caries in Primary Molars
Efficacy of Silver Diamine Fluoride Versus Nano-Silver Fluoride in Arresting Active Dentin Caries in Primary Teeth in Young Children
Early childhood caries is a major public health problem affecting preschool children worldwide. Silver Diamine Fluoride is a well-established non-invasive treatment for arresting caries; however, it causes black discoloration of…
- Trial name
- NCT07382245
- Testing
- Nano-Silver Fluoride, Silver Diamine Fluoride
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- October University for Modern Sciences and Arts
Caries; Dentin
SMART With Different Modifications in Asymptomatic Deep Carious Lesions of Primary Molars.
This study aimed to evaluate the clinical success of the 'Silver Modified Atraumatic Restorative Technique '(SMART) with different modifications in asymptomatic deep carious lesions of primary molars.
- Trial name
- NCT06645860
- Testing
- SDF+KI+LED Light 20s, SDF+KI
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Decayed Primary Molars, Decayed Tooth
Clinical Evaluation of Different Bulk-Fill Restorative Materials in Primary Molars
The goal of this clinical trial is to compare the clinical performance of chemically-cured and light-cured bulk-fill composite materials used for Class II restorations in children aged 4 to 9 years with primary second molars.
- Conditions
- Decayed Primary Molars, Decayed Tooth, Dentin Caries
- Trial name
- NCT07868016
- Testing
- Stela Capsule Bulk Fill Flowable Self-Cure Restorative, Filtek One Bulk Fill Restorative
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Burak Carıkcıoglu
Pulp Disease, Dental, Dental Caries
Dentin Bridge Formation After Indirect Pulp Capping With Bioactive Glass Incorporated in Resin Composite and Its Adhesive in Comparison With Light Cured Calcium Hydroxide
The aim of this study is to evaluate the effect of application of bioactive glass in different protocols on the formation of dentin bridge after indirect pulp capping using resin composite with its adhesive both are containing…
- Trial name
- NCT04274920
- Testing
- Bioactive Glass, Light cured calcium hydroxide
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dentin Caries
Evaluation of the Effect of Flowable Composites on Postoperative Sensitivity in Class I Restorations.
The aim of this study is to evaluate the effect of flowable conventional and bulk-fill composites on postoperative sensitivity in class I cavities over long-term follow-up.
- Trial name
- NCT07343050
- Testing
- Dental restorations
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University