Clinical trials: Caries; Initial
White Spot Lesion of Tooth, Orthodontic Treatment
S-PRG Filler for Preventing White Spot Lesions During Orthodontic Treatment
White spot lesions are early areas of enamel demineralization that may develop during orthodontic treatment with fixed braces. This study aims to evaluate the effectiveness of S-PRG Barrier Coat in preventing white spot lesions…
- Conditions
- White Spot Lesion of Tooth, Orthodontic Treatment, Enamel Demineralization, Fluoride Varnishes
- Trial name
- SPRG-WSL (NCT07839780)
- Testing
- S-PRG Barrier Coat, S-PRG Barrier Coat + 5% Sodium Fluoride Varnish, 5% sodium fluoride varnish
- Where
- Malaysia
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Caries Active, Dentin, Carious
Success of Zirconia and Stainless Steel Crowns for Permanent Molars
The purpose of this study is to evaluate and compare the clinical and radiographic performance of zirconia and stainless steel crowns on permanent molar
- Trial name
- NCT05049694
- Testing
- zirconia crowns, stainless steel crowns
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries in Children
Clinical and Radiographic Evaluation of Resin Endocrown as Long Term Interim Restoration Versus Stainless Steel Crown for Endodontically Treated First Permanent Molar in Children: Randomized Controlled Pilot Study.
management of endodontically treated first permanent molar with deep dental caries is one of the challenging procedure that the operator face.
- Trial name
- NCT05250609
- Testing
- Endocrown "composite".
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Dental Caries, Fissure Sealant
The Effect of an Adhesive System on the Retention and Caries Prevention for Fissure Sealants in Permanent Molars
Background: Resin-based fissure sealants (FS) are recommended to prevent pit-and-fissure caries development or prevent the progression of enamel caries lesion to frank cavitation into dentine.
- Trial name
- ResinFS (NCT06608563)
- Testing
- Fissure sealant without adhesive system (NO BOND), Fissure sealant with adhesive system (BOND)
- Where
- Ireland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Dental Caries, Compliance Behavior
Treatment of Initial Caries Lesions on Proximal Surfaces of Primary and Permanent Posterior Teeth
This study aims to evaluate the effectiveness of 30% silver diamine fluoride in the treatment of clinically caries lesions in enamel, with radiographic image restricted to the enamel or the outer third of dentin on the proximal…
- Trial name
- NCT01477385
- Testing
- Resin Infiltration, 30% Silver Diammine Fluoride, Dental Flossing
- Where
- Brazil
- Volunteers
- 183 people
- Sponsor
- University of Sao Paulo
Caries; Initial, Occlusal Caries
Early Treatments for Preventing Occlusal Caries Lesions
Sealants effectively arrest non-cavitated caries lesions on the fully erupted occlusal surface of permanent teeth. However, the clinical effectiveness of sealants is uncertain in preventing occlusal caries lesions in partially…
- Conditions
- Caries; Initial, Occlusal Caries, Caries,Dental
- Trial name
- NCT05969756
- Testing
- Fluoride varnish, Conventional etch and rinse sealant, Self-etch sealant
- Where
- 2 sites in Vietnam
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hue University of Medicine and Pharmacy
Dental Caries
Cost-efficacy of Silver Diammine Fluoride in Erupting Molars
This study aims to evaluate the cost-effectiveness of 30% silver diammine fluoride in the treatment of clinically caries lesions in enamel, on occlusal surfaces in first permanent molars compared to a control group that performs…
- Trial name
- NCT01508611
- Testing
- 30% silver diammine fluoride, Oral hygiene
- Where
- Brazil
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Carious Lesion, Caries; Initial
Effect of Self-assembly Peptide With or Without Laser on Remineralization of Initial Carious
This study aimed to asses the effect of different remineralizing agents on the initial carious lesions at diff rant after immediately after treatment (as baseline), six months and one year.
- Trial name
- NCT07574814
- Testing
- ER-CR Laser, Without ER-CR Laser
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Delta University for Science and Technology
Caries,Dental, Remineralization
Remineralization Efficacy of Gum Arabic Varnish.
The aim of this study is to evaluate the remineralizing capacity of Gum Arabic varnish and its implementation into clinical practice.
- Conditions
- Caries,Dental, Remineralization, White Spot Lesion
- Trial name
- NCT04422860
- Testing
- Gum Arabic varnish, Proflourid Varnish,VOCO, MI Varnish,GC Japan Inc.
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Remineralization of White Spot Lesions Using Self-Assembling Peptide P11-4 in Primary Anterior Teeth A Randomized Clinical Trial
This study is a randomized controlled clinical trial on primary anterior teeth of 3-5 year-old patients suffering from white spot lesions (ICDAS system II scores 1-2).
- Trial name
- NCT03927794
- Testing
- Self-Assembling Peptide P11-4
- Where
- Egypt
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Glass Ionomer Cement, Cost-effectiveness
Effectiveness and Economic Evaluation of Glass Ionomer Material Using as Dental Sealant
Eruption of the first permanent molar is the earliest in our oral cavity, leading to a high occurrence of dental caries in its pits and fissures.
- Conditions
- Glass Ionomer Cement, Cost-effectiveness, Pit and Fissure Caries (Disorder)
- Trial name
- NCT03034837
- Testing
- resin sealant, ART sealant
- Where
- 2 sites in China
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Zhengzhou University
Dental Caries, Early Caries Lesions
A Randomized Split-Mouth Clinical Trial Comparing Resin Infiltration and Microabrasion for Early Caries Lesions
This study aims to evaluate and compare the clinical characteristics and treatment outcomes of early caries lesions using resin infiltration (Icon) and microabrasion (Opalustre).
- Conditions
- Dental Caries, Early Caries Lesions, White Spot Lesions[Initial Caries]on Smooth Surface of Tooth
- Trial name
- ICON-CTU (NCT07544849)
- Testing
- Resin Infiltration, Microabrasion
- Where
- Vietnam
- Volunteers
- 30 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
Caries,Dental, Pit and Fissure Caries
Retention of a Flowable Resin-based Sealant With Two Types of Adhesives
The aim of the present study is to compare the use of two adhesives for the placement of occlusal sealants, evaluating their retention on the occlusal surfaces.
- Conditions
- Caries,Dental, Pit and Fissure Caries, Sealant Dental
- Trial name
- NCT04945382
- Testing
- Scotchbond Universal 3M, Single Bond 3M
- Where
- Peru
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National University of San Marcos, Peru
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Clinical Evaluation of the Efficacy of SPR-G Barrier Coat Versus Fluoride Varnish Versus MI Paste in the Treatment of Early White Spot Lesions in Pediatric Patients
In-Vivo randomized clinical trial to compare between the clinical performance of fluoride varnish versus MI paste (CPP_ACP) and the PRG- Barrier coat material concerning enamel remineralization, arrest of active early lesions…
- Trial name
- NCT05202821
- Testing
- PRG Barrier Coat, Fluoride varnish, MI paste
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Caries; Initial
Efficacy of Resin Infiltration of Proximal Caries
The aim of the present study was to assess the clinical efficacy of resin infiltration of interproximal caries lesions using a novel measure method-----DIAGNOcam.
- Trial name
- RIDCBW (NCT04092296)
- Testing
- resin infiltration, remineralization
- Where
- China
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Wuhan University
Sound Newly Erupted First Permanent Molars With Deep Fissures Susceptible to Caries
Evaluation of Retention for Hydrophilic and Hydrophobic Sealants in Uncooperative Children
To evaluate and compare the retention and cariostatic effect of hydrophilic and hydrophobic resin-based sealants for sealing pits and fissures of permanent molars in uncooperative children.
- Trial name
- NCT04560985
- Testing
- Hydrophilic fissure sealant, Hydrophobic fissure sealant
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
White Spot Lesion of Tooth
Fluoride Varnish, Ozone, Octenidin and WSLs in Orthodontic Patients
Objectives: to assess the efficiency of four prophylactic protocols on white spot lesions during orthodontic treatment: 1. professional mechanical tooth cleaning (PMTC)+fluoride varnish, 2.
- Trial name
- NCT04992481
- Testing
- PMTC, fluoride varnish, gaseous ozone therapy
- Volunteers
- 150 people
- Sponsor
- Pomeranian Medical University Szczecin
White Spot Lesion of Tooth
Color Masking Potential of Bioactive and ICON Materials
The non cavitated white-spot lesion (WSL) occurs after sometime during fixed orthodontic treatments, and their treatment is mandatory before going into frank cavitation.
- Trial name
- NCT06402500
- Testing
- Icon Infiltrant, Bioactive infiltrant
- Where
- Jordan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
White Spot Lesion of Tooth
RMGI Varnish Versus APF Gel in Prevention of White Spot Lesions During Orthodontic Treatment
evaluate the effect of a single application of Clinpro XT varnish on enamel demineralization adjacent to orthodontic brackets during fixed orthodontic treatment in comparison with acidulated phosphorus fluoride gel.
- Trial name
- NCT03721198
- Testing
- Acidulated phosphorous flouride, Resin modified glass ionomer varnish
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mohamed zidan
Dental Caries
Preventive Regimens With Herbal and Fluoride Toothpaste on Remineralization in High Caries Patients With Initial Lesions
This study will be conducted to assess the effect of different preventive regimens using herbal toothpaste versus fluoride toothpaste on the management of remineralization and caries risk in high caries risk patients.
- Trial name
- NCT04446390
- Testing
- Himalaya complete care toothpaste, colgate cavity protection
- Where
- 2 sites in Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University