Clinical trials: Caries Assessment, open to volunteers
Composite Resins, Dental Caries Class II
Bulk-Fill Composite Restorations: Clinical Evaluation
This randomized controlled clinical study aims to evaluate the clinical performance of five different bulk-fill composite materials representing distinct technological approaches according to the World Dental Federation (FDI)…
- Trial name
- NCT07518537
- Testing
- Thermoviscous bulk-fill composite restoration, Sonic-activated bulk-fill composite restoration, Flowable bulk-fill composite restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Dental Caries, Dental Cavities
Evaluation of Selective and Stepwise Excavation in Young Permanent Teeth With Deep Caries Lesions.
The purpose of this clinical trial is to evaluate and compare the outcomes of selective carious tissue removal versus stepwise carious tissue removal in young permanent teeth with deep carious lesions.
- Trial name
- SELECT (NCT06944028)
- Testing
- Selective excavation, Stepwise excavation
- Where
- Sweden
- Volunteers
- 666 people
- Sponsor
- Karolinska Institutet
Caries,Dental
CARDEC-PEL: Comparison of Two Methods of Caries Risk Assessment in Children
The aim of the study was to compare dental caries treatment and follow-up based on an elaborate and individualized assessment of caries risk in children, to a simpler risk assessment strategy by means of a double-blind randomized…
- Trial name
- NCT03969628
- Testing
- ICCMS
- Where
- Brazil
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Dental Caries
Clinical and Radiographic Assessment of First Permanent Molars With Cention-N
: Assessment of Clinical, Radiographic, and Oral Health-Related Quality of Life Following Restoration of First Permanent Molars with Cention N: A 12-Month Split-Mouth Randomized Controlled Trial Introduction Dental caries is one…
- Trial name
- Cention-N (NCT07703176)
- Testing
- Cention-N, Resin Composite
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Dental Caries in Primary Molars
Clinical Comparison of Cariclast Gel and Rotary Drilling Technique for Caries Removal in 2d Primary Molars
This randomized clinical trial aims to compare two different methods of caries removal in primary molars: the chemomechanical technique using Cariclast gel and the conventional rotary drilling method.
- Trial name
- CARICLAST-RCT (NCT07270458)
- Testing
- cares removal using cariclast gel, Conventional Mechanical Caries Removal
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Root Caries
Evaluation of Corrective Surgery Versus Dental Implants in Compromised Upper Molars
This study seeks to assess the clinical, radiographic, and patient-reported outcomes of root amputation versus implant over a 12 months period, generating robust evidence to guide clinical decision-making and enhance patient care.
- Trial name
- NCT07608497
- Testing
- root amputation
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Deep Caries Lesion of Pemanent Teeth
Adjustment Period for Partial Crowns
The aim of this study is to compare the occlusal accuracy of CAD/CAM milled and 3D printed crowns guided by an occlusal device, starting from the same digital CAD design.
- Trial name
- Adjustment per (NCT07051590)
- Testing
- cad cam, 3D printer
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ceren Sire
Dental Caries, Reversible Pulpitis
Assessment of Pain and Anxiety During Infiltration Anesthesia Using Dental Anesthesia Injector Versus Conventional Syringe in Pediatric Patients
This randomized controlled trial is conducted on pediatric dental patients to compare the effectiveness of local anesthesia administered using a dental anesthesia injector device versus the traditional syringe method.
- Trial name
- NCT07101068
- Testing
- Dental Anesthesia Injector, conventional syringe
- Where
- 2 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Nursing Students, Nursing Caries
Flipped Learning Model on Nursing Students' Thorax and Heart Examination
This study is planned to determine the impact of education provided with the flipped learning model on nursing students' thorax and heart knowledge and self-directed learning skills.
- Conditions
- Nursing Students, Nursing Caries, Nurse's Role
- Trial name
- NCT06397547
- Testing
- Flipped Learning
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Dental Caries, White Spot Lesions
QLF and Digital Imaging for Caries Activity Assessment After Orthodontic Treatment
This prospective longitudinal observational study aims to evaluate the diagnostic performance and agreement of Smartphone photography, intraoral 3D imaging, Quantitative Light-Induced Fluorescence Digital (QLF-D), and ICDAS…
- Conditions
- Dental Caries, White Spot Lesions, Caries Lesion Activity, Post-Orthodontic Enamel Demineralization
- Trial name
- NCT07608471
- Volunteers
- 30 people
- Sponsor
- Universidad El Bosque, Bogotá
Composite Post, Intracanal Reinfocement
Evaluation of Intracanal Reinforcement with Short Composite Post in Upper Primary Incisors with Severly Carious Teeth As in Early Childhood Caries Cases Using Randomized Clinical Trial
Severely damaged incisors may lead to difficulty in speech, decreased masticatory efficiency, abnormal tongue habits, subsequent malocclusions, and psychological and self-esteem problems.
- Trial name
- NCT06740643
- Testing
- intracanal reinforcement using short composite post, no intracanal reinforcement
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Cairo University
Early Childhood Caries (ECC)
Analysis of Salivary Proteins in Young Children as an Device to Improve Caries Risk Assessment
The goal of this observational study is to learn if the composition of salivary proteins in 3-year-old children, from communities with documented varying caries risks, can be used to identify future diagnostic predictors for…
- Trial name
- DecodECC (NCT06957509)
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Dentin Caries
Evaluation of the Clinical Performance of Different Composite Materials in Class III and IV Restorations.
In this study, a universal adhesive was used with different adhesive techniques (self-etch and total-etch modes) and evaluated for 18 months in three different types of composite material class III and class IV restorations…
- Trial name
- NCT07343063
- Testing
- Composite materials
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Recep Tayyip Erdogan University
Dental Caries, Detection
Comparing Fluorescent Starch Nanoparticles Rinse with ICDAS for Early Caries Detection in Children
The present study aims to evaluate the diagnostic accuracy of fluorescent starch nanoparticles caries detection rinse versus the International Caries Detection and Assessment System (ICDAS) in identifying early dental caries…
- Conditions
- Dental Caries, Detection, Fluorescence, Diagnostic Accuracy
- Trial name
- FSNCDR-ICDAS (NCT06761248)
- Testing
- Fluorescent Starch Nanoparticles Caries Detection Rinse
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Cairo University
Dental Caries, Composite Resins
Clinical Evaluation of Dentin Replacement Materials in Posterior Composite Restorations
This randomized controlled clinical trial is designed to clinically evaluate and compare the performance of five dentin replacement materials used beneath posterior composite restorations.
- Conditions
- Dental Caries, Composite Resins, Composite Restoration
- Trial name
- NCT07762651
- Testing
- Biodentine, ACTIVA BioACTIVE, glass ionomer cement
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Dental Caries, Primary Molars
Clinical Performance of Four Restorative Materials in Primary Molars
This randomized clinical trial aims to compare the clinical and radiographic performance of four direct restorative materials used for restoring carious primary molars in children.
- Trial name
- NCT07504393
- Testing
- Cention N, Stela, SDI, Australia, Beautifil II, Shofu, Japan
- Volunteers
- 92 people
- Sponsor
- Al-Azhar University
Dental Caries
The Study Aims to Compare the Effectiveness of Mesoporous Bioactive Glass-containing Adhesives vs Conventional Universal Adhesives on the Clinical Performance Composite Restorations Through Promoting Dentin Remineralization After Selective Caries Removal Over a Two-year Follow-up
a two-year, double-blind, randomized controlled trial evaluates the effectiveness of a bioactive glass adhesive (Hi-Bond Universal) versus a conventional adhesive (OptiBond Universal) in Class II carious lesions.
- Trial name
- NCT06990945
- Testing
- Hi-Bond Universal Adhesive, OptiBond Universal Adhesive
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Teledentistry
Accuracy of Teledentistry for Diagnosis and Treatment Need in Dental Caries Detection Versus Clinical Examination on a Group of Egyptian Children: A Diagnostic Accuracy Study
The aim of this study is to assess the accuracy of teledentistry for diagnosis and treatment need in dental caries detection versus clinical examination on a group of Egyptian children.
- Trial name
- NCT06600360
- Testing
- Teledentistry
- Volunteers
- 102 people
- Sponsor
- Cairo University
Pulpitis - Reversible, Occlusal Caries
Evaluation of Cytokines Level as an Indicator of Pulp Inflammation and Its Relation to the Success Rates of Pulpotomy in Primary Molars Affected With Proximal Versus Occlusal Decay
pulpotomy will be done I primary molars with occlusal or proximal decay and level of cytokines will be measured as an indicator for pulp inflammation levels
- Conditions
- Pulpitis - Reversible, Occlusal Caries, Proximal Caries
- Trial name
- NCT07171229
- Testing
- Pulpotomy, Measuring Cytokines level
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Cairo University
Dental Caries, Tooth Demineralization
Evaluation of Optical Coherence Tomography in Dentistry
Optical coherence tomography (OCT) is a medical diagnostic tool, providing non-invasive, non-radiative and high resolution imaging. OCT has been established since many years in ophthalmology.
- Trial name
- NCT03753256
- Testing
- Transbond XT, Protecto®CaF2Nano, Pro Seal®
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Heidelberg Medical Center