Clinical trials: Caries Assessment, active
Carious Lesion, Ready-made Crowns
The Relation Between Oral Hygiene and Microbial Load in the Oral Cavity After Restoring Primary Molars With Two Types of Ready-made Crowns
Following the restoration of primary molars with stainless steel and bioflex crowns, an evaluation of the current state of oral hygiene in relation to the amount of microorganisms and gingival health in the oral cavity will be…
- Trial name
- bioflex crown (NCT06767670)
- Testing
- stainless steel crown, bioflex crown
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Carious Teeth, Adaptation
Marginal Evaluation of Zirconia Reinforced Lithium Disilicate Partial Coverage Restoration of Egyptian Posterior Teeth.
Objective: To evaluate the marginal adaptation of the zirconia reinforced lithium disilicate (VITA AMBRIA) glass ceramic Inlay/Onlay compared with lithium disilicate(IPS emax Press) glass ceramic Inlay/Onlay in decayed posterior…
- Trial name
- NCT05281861
- Testing
- Zirconia reinforced Lithium disilicate (Vita Ambria) ceramic onlay restoration, Lithium disilicate (IPS e-max press) ceramic onlay restoration
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries, Cervical Caries
The Effectiveness RMGI and Giomer, Individually and Combined Anterior Cervical Caries
This study compares the effectiveness of three dental materials for restoring anterior cervical caries in high-risk patients: resin-modified glass ionomer (RMGI), Giomer, and a combination technique where RMGI is veneered with…
- Trial name
- NCT06901453
- Testing
- Low shrinkage Giomer restorative material (Beautifil II LS), RMGI alone - Control
- Volunteers
- 75 people
- Sponsor
- Cairo University
Tooth Diseases
Clinical Evaluation of Three Different Universal Adhesives in Non-carious Cervical Lesions
The aim of this randomized, controlled prospective clinical trial is to evaluate and compare the performances of three different universal adhesives using a flowable universal composite resin in the restoration of non-caries…
- Trial name
- NCT03415412
- Testing
- Clearfil Univesal Bond, IBond Universal, G-Premio Bond
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries
Evaluation of the Salivary-free Amino Acids Levels (Glycine , Proline , Lysine , and Alanine ) With Caries Activity
This study will be aimed to investigated the correlation between levels of salivary amino acids (glycine , proline , lysine , alanine ) in the saliva of healthy children with and without active carious lesions and to estimate the…
- Trial name
- NCT06953557
- Testing
- To compare the effect of salivary glycine , proline , lysine and alanine concentration between participants with high caries activity and participants with negative caries activity
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Dental Caries, White Spot Lesions
QLF and Digital Imaging for Caries Activity Assessment After Orthodontic Treatment
This prospective longitudinal observational study aims to evaluate the diagnostic performance and agreement of Smartphone photography, intraoral 3D imaging, Quantitative Light-Induced Fluorescence Digital (QLF-D), and ICDAS…
- Conditions
- Dental Caries, White Spot Lesions, Caries Lesion Activity, Post-Orthodontic Enamel Demineralization
- Trial name
- NCT07608471
- Volunteers
- 30 people
- Sponsor
- Universidad El Bosque, Bogotá
Caries Active, Caries Root
Surface Caries Feature Study
Dental caries (dental cavity) is very common and can impact oral health and oral health-related quality of life. Dental caries is when the tooth surfaces break down, and if left untreated, can cause tooth pain.
- Conditions
- Caries Active, Caries Root, Caries,Dental, Caries; Initial
- Trial name
- NCT07048444
- Testing
- N/A as observational study
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- 3Shape A/S
Deep Caries, Dental Caries
Evaluation of Bioactive Giomer Material Versus Nanohybrid Resin Composite in Deep Marginal Elevation
This study will be conducted to evaluate the clinical, radiographic and periodontal performance of bioactive Giomer compared to nanohybrid resin composite restoration in deep subgingival proximal cavities extending below the CEJ…
- Trial name
- NCT06497231
- Testing
- Beautifil II LS, Nanohybrid resin composite material
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries (Diagnosis), Dental Plaque (Diagnosis)
Assessment of Dental Pathologies Using Digital Tools
Digital technology is playing an increasingly important role in dentistry, because of its ability to support the practitioner and increase work efficiency.
- Conditions
- Dental Caries (Diagnosis), Dental Plaque (Diagnosis), Periodontitis
- Trial name
- RESTODATA-NUM (NCT07205588)
- Where
- 22 sites in France, Reunion
- Volunteers
- 350 people
- Sponsor
- Recherche Clinique en Odontologie (ReCOL)
Dental Caries, Pulpotomy
Comparison of Clinical Success of Stainless Steel Crowns and Zirconia Crowns in Primary Molars
Evaluation and understanding of clinical success, parental satisfaction and effects on periodontal tissues are the main expected benefits of prefabricated zirconia crowns and prefabricated stainless steel crowns.
- Trial name
- NCT06685640
- Testing
- prefabricated stainless steel crowns, prefabricated zirconia crowns
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Deep Carious Lesions
Clinical Performance of Resin Composite Restoration After Dentin Biomodification by Grape Seed Extract in Deep Carious Lesions.
This study will evaluate the clinical and radiographic performance of resin composite restoration after utilized a grape seed extract as dentin biomodification in vital teeth with deep occlusal carious lesions (ICDAS 5-6) after…
- Trial name
- GSE (NCT06780527)
- Testing
- 15% Grape seed extract as dentin pretreatment
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Primary Molars
Clinical Performance of Four Restorative Materials in Primary Molars
This randomized clinical trial aims to compare the clinical and radiographic performance of four direct restorative materials used for restoring carious primary molars in children.
- Trial name
- NCT07504393
- Testing
- Cention N, Stela, SDI, Australia, Beautifil II, Shofu, Japan
- Volunteers
- 92 people
- Sponsor
- Al-Azhar University
Root Caries
Evaluation of Corrective Surgery Versus Dental Implants in Compromised Upper Molars
This study seeks to assess the clinical, radiographic, and patient-reported outcomes of root amputation versus implant over a 12 months period, generating robust evidence to guide clinical decision-making and enhance patient care.
- Trial name
- NCT07608497
- Testing
- root amputation
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries
Zirconomer-P Versus RMGI for Proximal Restorations in Primary Molars
Clinical trial comparing two tooth-colored restorative materials for treating cavities between the teeth of primary molars in children aged 4 to 7 years.
- Trial name
- NCT07788274
- Testing
- Zirconia-fortified glass ionomer, Resin-modified glass ionomer
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
MIH, Molar-Incisor Hypomineralization
Effects of Silver Diamine Fluoride and Intraoral Cryotherapy on Local Anesthesia in MIH-Affected Molars
Molar-incisor hypomineralization (MIH) is a developmental enamel defect of unclear etiology that affects permanent first molars and often permanent incisors, leading to increased porosity, hypersensitivity, and poor prognosis.
- Conditions
- MIH, Molar-Incisor Hypomineralization, Caries Assessment
- Trial name
- NCT07326241
- Testing
- Standard Local Anesthesia, Intraoral Cryotherapy, Silver Diamine Fluoride (SDF)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Molar Incisor Hypomineralization, Hypersensitivity
Intraosseous vs Infiltration Anesthesia in Molar-Incisor Hypomineralization (MIH) Children
This study aims to compare the effectiveness of intraosseous and infiltration anesthesia techniques administered using a computer-assisted anesthesia device (SleeperOne® 5; Dental HiTec, France) during restorative treatments of…
- Trial name
- MIH (NCT07352813)
- Testing
- Intraosseous anaesthesia using a computerized system, Infiltration anaesthesia using a computerized system
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Pulptomy, Dental Caries
Effect of Ferric Sulphate and Putty MTA as Pulpotomy Agent in Vital Primary Teeth
The pulp in primary teeth has a high potential for repair because of high degree of cellularity and vascularity. The rationale for the pulpotomy procedure is that the radicular pulp tissue is healthy and capable of healing after…
- Conditions
- Pulptomy, Dental Caries, Pulp Therapy
- Trial name
- CT (NCT07324928)
- Testing
- Ferric sulphate, Putty MTA
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Jazan
Dental Caries, Caries Risk
Validation of a Digital Caries Risk Assessment Questionnaire Against the CAMBRA Protocol in an Egyptian Adult Population
This study is designed as a cross-sectional diagnostic agreement study conducted in accordance with the Standards for Reporting Diagnostic Accuracy Studies (STARD 2015) and the Guidelines for Reporting Agreement and Precision of…
- Trial name
- NCT07716254
- Testing
- Digital Caries Risk Assessment
- Where
- Egypt
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Early Childhood Caries (ECC)
Caries Risk in Children Treated Under General Anesthesia for Early Childhood Caries
This observational, cross-sectional study aims to evaluate the current caries risk profiles of children who underwent dental treatment under general anesthesia (GA) for early childhood caries (ECC) between 2015 and 2020 at Aydın…
- Trial name
- NCT07330570
- Testing
- Caries Risk Assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
White Spot Lesions, White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Assessing the Effects of Resin Infiltration and Resin Modified Glass Ionomer on the Color Changes of White Spot Lesions in a Clinical and Laboratory Setting
The goal of this clinical trial is to assess the efficacy of "Icon® resin infiltration" and "VanishTM XT varnish" in restoring the appearance of white spot lesions WSLs in healthy children affected with anterior white spot…
- Conditions
- White Spot Lesions, White Spot Lesions [Initial Caries] on Smooth Surface of Tooth, Enamel Hypomineralization
- Trial name
- RI (NCT06696105)
- Testing
- Resin infiltration, Vanish XT varnish (resin modified glass ionomer restoration)
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University