Clinical trials: Caries Prevention
Dental Caries
Early Childhood Caries Prevention: Effectiveness of Mother-Child Oral Health Care Programme (BASIS)
The goal of this two-arm, parallel-group cluster randomized controlled trial was to assess the effectiveness of the mother-child initiated oral health care program, termed BASIS, in preventing early childhood caries (ECC).
- Trial name
- NCT06944977
- Testing
- Anticipatory guidance and postnatal home visits, Anticipatory guidance
- Where
- Malaysia
- Volunteers
- 154 people
- Sponsor
- NORKHAFIZAH SADDKI
Caries Active, Prevention
Children in the Operating Room: Kids That go Thru Operating Room Will be Given a Connected Health Toothbrush, Kids Anticavity Toothpaste and Behavioral Health Intervention to Reduce Claim Costs
The objective of this study is to demonstrate that compliance and brushing adherence as a treatment to providers, insurance company and State Health Departments that can help improve oral health of children who have already been…
- Trial name
- NCT07539064
- Testing
- Connected Toothbrush with a behavioral health intervention
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Colgate Palmolive
Dental Caries in Children
Tooth Smart Healthy Start: Oral Health Advocates in Public Housing
Dental caries is the most common chronic disease of childhood and is increasing in prevalence in children 2-5 years old. Racial and ethnic minority groups as well as economically disadvantaged individuals are affected the most by…
- Trial name
- NCT01205971
- Testing
- Motivational Interviewing, Dental Preventive Services
- Where
- United States
- Volunteers
- 2,842 people, healthy volunteers welcome
- Sponsor
- Boston University
Dental Caries
Comparative Effectiveness of Treatments to Prevent Dental Caries
Dental caries (tooth decay) is the most prevalent childhood disease in the world. Multiple interventions are available to treat and prevent caries.
- Trial name
- NCT03448107
- Testing
- Silver Diamine Fluoride, Fluoride Varnishes, Glass Ionomer
- Where
- United States
- Volunteers
- 3,345 people, healthy volunteers welcome
- Sponsor
- NYU College of Dentistry
Dental Caries, Dental Plaque
RCT on Effectiveness of Oral Health Preventive Programmes in School Children in Uganda
Dental caries represents a challenge for Oral Health Services in several African Countries, like Uganda. Few studies have been reported the burden of oral health, its prevention and non-operative treatment among school children…
- Conditions
- Dental Caries, Dental Plaque, Dental Diseases, Dental Caries in Children
- Trial name
- NCT06081868
- Testing
- Use of toothbrush/toothpaste/fluoride varnish, Education on nutrition/oral hygiene
- Where
- Switzerland
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- University of Bern
Caries
Effect of the Use of Xylitol Gum in the Prevention of Caries Lesions in Children Living in Ladakh
Background: Ladakh is a region administered by India, covering an area slightly larger than Croatia; it is part of the larger region of Kashmir and Jammu.
- Trial name
- CaPreXCh (NCT04420780)
- Testing
- Administration of sugar-free gums sugar-free gums containing 100% Xylitol as sweetener, Administration of sugar-free gums sugar-free gums containing containing a polyols mixture plus a low amount of Xylitol (22%)
- Where
- Russia
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Bern
Root Caries
Prevention and Arrest of Root Caries Lesions with High Fluoride Concentration Mouthwash Versus Normal Fluoride Concentration Mouthwash in Elderly Patients
The study evaluats the effectiveness of regular fluoride 220 ppm F with erythritol and high fluoride 500 ppm F with erythritol mouthwashes against a placebo (regular fluoride 220 ppm F mouthwash) in the prevention of new root…
- Trial name
- NCT06723054
- Testing
- regular fluoride 220 ppm F mouthwash without erythritol, regular fluoride 220 ppm F mouthwash with erythritol, high fluoride 500 ppm F mouthwash with erythritol
- Where
- Switzerland
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Murali Srinivasan, Dr. med. dent., BDS, MDS, MBA, MAS
Dental Caries
Evaluation of CAMBRA Versus ICCMS Caries Risk Assessment Models Acquisition On Treatment Plan
randomized clinical study to evaluate 'caries management by risk assessment' Versus 'international caries classification and management system' Caries Risk Assessment Models Acquisition On Treatment Plan In Young Adult Population…
- Trial name
- NCT03668093
- Testing
- ICCM, CAMBRA
- Where
- Egypt
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries in Children
Effect of Sugar-Free Chewing Gum Containing Tulsi Extract on Salivary Streptococcus Mutans in a Group of Children
The goal of this clinical trial was to explore how adding Tulsi extract, a natural plant substance, to chewing gum affects the levels of Streptococcus mutans, type of bacteria that cause dental caries, in the saliva of children…
- Trial name
- NCT06174194
- Testing
- Tulsi Gum
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Faculty of Dental Medicine for Girls
Early Childhood Caries
A Telephone-based Case-management Intervention for Caries Prevention in Children With Severe Early Childhood Caries
Despite improvements in oral health among children, children living in areas characterized by low socio-economic status still have a significant disease burden with regard to dental caries.
- Trial name
- NCT02487043
- Testing
- A telephone-based case-management intervention
- Where
- Sweden
- Volunteers
- 151 people
- Sponsor
- Karolinska Institutet
Dental Caries, Oral Health Behavior Change
Assessing the Impact of a Social Media-Based Educational Intervention Using WhatsApp Video Messages on Dental Caries Prevention Knowledge, Oral Hygiene Practices, and Attitudes Toward Dental Health Among Primary School Children Aged 10-12 Years in Public Schools in Cairo Governorate, Egypt: A Quasi-
The goal of this study is to learn if educational videos sent through WhatsApp can improve dental health knowledge, healthy habits, and attitudes in primary school children aged 10 to 12 years in Cairo, Egypt.
- Conditions
- Dental Caries, Oral Health Behavior Change, Oral Hygiene, Oral Health, Knowledge, Attitudes, Practice
- Trial name
- NCT07363317
- Testing
- WhatsApp-Based Dental Health Education for Children
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rana Mohamed Ahmed Farghal
Caries Prevention, Fissure Sealant
A Trial of Caries Prevention Effect of Fissure Sealants
The purpose of this randomized clinical trial was to compare caries prevention of a conventional resin-based sealant and a glass-ionomer sealant placed on occlusal pits and fissures over a one year period in a high caries…
- Conditions
- Caries Prevention, Fissure Sealant, Fluoride Concentration, Glass Ionomer Cement
- Trial name
- NCT02063815
- Testing
- Fissure sealant application
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dental Caries
Oral-Spray Bacillus Spore Probiotic in Preventing and Supporting Treatment of Dental Caries in Children
Despite advances in oral health care, cavities remain highly prevalent worldwide, especially among children. Conventional treatment methods focus on removing damaged tooth tissue but fail to completely eliminate or control…
- Trial name
- NCT07241052
- Testing
- oral-spray 0.9% NaCl physiological saline solution, Smile Care
- Where
- Vietnam
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Anabio R&D
Caries,Dental, Tooth Decay
KAP of Dental Practitioners Regarding CRA
The aim of the study is to evaluate the knowledge, attitude, and practice of a group of dental practitioners from Cairo and Riyadh regarding caries risk assessment and management.
- Conditions
- Caries,Dental, Tooth Decay, Tooth Diseases
- Trial name
- NCT05792215
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries, Dental
Effect of Caries Conceptualizing and Residential University Life
The study aims to detect the conceptualization of dental caries among dental student and compare the caries prevalence in residential and non residential dental student
- Trial name
- NCT06595589
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- Sara Ibrahim Ahmed Hedia
Fissure Sealant
Glass Ionomer-Based Fissure Sealants in Children
This study aimed to comparatively evaluate the 24-month clinical retention performance and caries-preventive efficacy of three glass ionomer-based fissure sealants with different compositions.
- Trial name
- Sealant (NCT07388472)
- Testing
- Retention of Fissure Sealants
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
White Spot Lesion of Tooth
Fluoride Varnish, Ozone, Octenidin and WSLs in Orthodontic Patients
Objectives: to assess the efficiency of four prophylactic protocols on white spot lesions during orthodontic treatment: 1. professional mechanical tooth cleaning (PMTC)+fluoride varnish, 2.
- Trial name
- NCT04992481
- Testing
- PMTC, fluoride varnish, gaseous ozone therapy
- Volunteers
- 150 people
- Sponsor
- Pomeranian Medical University Szczecin
Dental Caries
Effectiveness of Fissure Sealant and Topical Fluoride Application in Preventing Dental Caries
Nearly half of the 12-year-old children in China have dental caries (tooth decay) and most of the lesions are in the fissures of the first permanent molars.
- Trial name
- NCT01446107
- Testing
- placement of fissure sealant, fluoride varnish, silver fluoride
- Where
- China
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dental Caries
Caries-preventive Effect of a Dentifrice Containing 5,000 Ppm Fluoride in Orthodontic Patients
AIM: To evaluate the efficacy of daily tooth brushing with high concentrated fluoride dentifrice on white spot lesion (WSL) formation in adolescents during treatment with fixed orthodontic appliances (FOA).
- Trial name
- NCT01768390
- Testing
- toothpaste containing 5,000 ppm fluoride, 1450 GCP
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- University of Copenhagen
Dental Caries
Effect of Erythritol and Xylitol on Dental Caries Prevention in Children
This study aims at demonstrating the effect of erythritol and xylitol lozenges on preventing the new caries lesions and the possible remineralization effect of both polyols on incipient caries lesions.
- Trial name
- NCT01062633
- Testing
- A, erythritol, xylitol, C, sorbitol
- Where
- Estonia
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Tartu