Clinical trials: Caries Prevention
Caries Prevention
Efficacy and Cost-effectiveness of Different Caries Preventive Protocols
To compare the caries preventive efficacy of clinical-based, home based or E-based oral health interventions and their cost effectiveness.
- Trial name
- NCT05962632
- Testing
- Fluoride based varnish (Dentkist Charm Fill Varnish ), pro care gel remineralizing agent, Mobile application
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Roya mohamed Hamad Elmaghrbi
Dental Caries, Dental Caries of Root Surface
Silver Diamine Fluoride for Caries Prevention in Removable Partial Dentures Wearers
This study measures and compares the effect of silver diamine fluoride (SDF) on caries increment in removable partial denture wearers. Half of the participants will SDF and while the other half will receive placebo.
- Trial name
- NCT03185104
- Testing
- Silver Diamine Fluoride, Distilled Water
- Volunteers
- 196 people
- Sponsor
- The University of Hong Kong
Caries,Dental
Fluoride Caries-control Effectiveness/Feasibility in Children
The aim of this study is to compare the effectiveness and feasibility of using silver diamine fluoride solution (SDF) vs. sodium fluoride varnish (NaF) for caries management in children from Bogotá (and its suburban areas) and…
- Trial name
- NCT06690008
- Testing
- Experimental group
- Where
- 2 sites in Colombia
- Volunteers
- 814 people, healthy volunteers welcome
- Sponsor
- Universidad El Bosque, Bogotá
Prevention of Dental Caries
Effect of Bioactive Glass Varnish on Salivary Parameters in Children: Randomized Controlled Trial
This study is a two-arm parallel randomized controlled trial led by Principal Investigator Inas Karawia at the Faculty of Dentistry, designed to evaluate and compare the short-term (immediatly) and sustained (over 6 months)…
- Trial name
- NCT07875387
- Testing
- Bioactive glass topical varnish, Fluoride varnish
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria
Dental Caries
Fluoride Varnish in the Prevention of Dental Caries in Aboriginal and Non-aboriginal Children
The purpose of this study is to determine whether semi-annual fluoride varnish applications combined with caregiver counseling are effective in preventing and reducing a severe form of dental decay, known as early childhood…
- Trial name
- NCT00435500
- Testing
- Fluoride varnish
- Where
- Canada
- Volunteers
- 1,320 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Dental Caries
Three Measures for the Prevention of Carious Lesions in Preschool Children
Analysis different measures preventive effect on carious Lesions incidence and oral microecological system change of preschool children
- Trial name
- NCT02341352
- Testing
- fluoride varnish, Immunoglobulin Yolk, Probiotics
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Early Childhood Caries, Dental Caries in Children
Treatment of Early Childhood Caries Using Silver Diammine Fluoride and Sodium Fluoride Tricalciumphosphate and the Effects on Oral Health Related Quality of Life
There is still a need for the assessment of different minimal intervention strategies and treatments focusing on the prevention and arrest of carious lesions of primary molars The evidence-based clinical practice guideline on…
- Conditions
- Early Childhood Caries, Dental Caries in Children, Dental Caries Extending Into Dentin, Dental Caries
- Trial name
- NCT05772039
- Testing
- Topical application of 38% Silver Diammine Fluoride Solution, Topical application of 5% Sodium Fluoride with functional Tricalcium phosphate Varnish
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Universiti Sains Malaysia
Dental Caries of Root Surface, Aging
Domiciliary Professional Oral Care for Dependent Older Adults
Keep brushing your teeth, twice a day, during life for healthy teeth and body. Not brushing your teeth regularly and well, may have a devastating effect on your teeth and your general health.
- Trial name
- HET (NCT05335239)
- Testing
- Professional dental cleaning
- Where
- Sweden
- Volunteers
- 194 people
- Sponsor
- Karolinska Institutet
Dental Caries, Occlusal Caries
Polishing vs Hydrogen Peroxide: Effect on DIAGNOdent Readings in Stained Fissures
This study compared two methods of cleaning stained pits and grooves (fissures) on the chewing surfaces of back teeth before measuring them with a laser fluorescence device (DIAGNOdent), which is used to help detect early tooth…
- Trial name
- NCT07763470
- Testing
- Mechanical Polishing with Fluoride-Free Prophylaxis Paste, 35% Hydrogen Peroxide Application
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Özlem Erçin Sultanzade
Caries, Dental
Prevention of Adult Caries Study (PACS)
Adult tooth decay is an infectious disease that afflicts the majority of Americans aged 55 and older and is the most common chronic disease at midlife with an ever growing economic toll.
- Trial name
- NCT00357877
- Testing
- 10% w/v chlorhexidine acetate coating FDA IND #45466
- Where
- 4 sites in United States
- Volunteers
- 983 people
- Sponsor
- Tufts University
Caries Prevention
Comparison of the Efficacy of Three Preventive Methods to Reduce the Incidence of Coronal Caries in Schoolchildren
The objective of this clinical trial is to compare the efficacy of three preventive methods in reducing the incidence of coronal caries in the first permanent molars of Mexican schoolchildren.
- Trial name
- NCT07131358
- Testing
- Glass ionomer pit and fissure sealant plus fluoride varnish, Pit and fissure sealant with Giomer® technology, Fluoride varnish
- Where
- 3 sites in Mexico
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Carious and Non-carious Lesions of the Teeth
Comparative Evaluation of Dental Disease Prevention Programs
Relevance. The dental health of the Chapaevsk children's population and the risk factors for dental caries and periodontal disease were well studied in 1995-2009.
- Trial name
- NCT05767281
- Testing
- prevention program
- Where
- Russia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Samara State Medical University
Hypersensitivity
Caries Prevention Products & Dentinal Hypersensitivity
The aim of this pilot research project is to compare the clinical effect on dentinal hypersensitivity of three products: Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) paste with fluoride, 5000 Sodium Fluoride (NaF)…
- Trial name
- NCT02136576
- Testing
- Sensodyne, Crest Cavity Protection & MI Paste Plus, Clinpro 5000
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Tufts University
Dental Caries
Effectiveness of Fluoride Varnish in Prevention of Dental Caries in School Children
Despite the availability of free health dental service in Sri Lanka, the prevalence and severity of dental caries among 6year old school children stand at a very high level according to the results of national oral health survey…
- Trial name
- NCT02877888
- Testing
- fluoride varnish 22600ppm
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Peradeniya
Caries,Dental
Birth to Three - Cavity Free
Early childhood caries (ECC) is a potentially painful and debilitating disease, which represents a significant public health problem among young children.
- Trial name
- BTCF (NCT05756413)
- Testing
- Self-determination theory
- Where
- 16 sites in United States
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Dental Caries and Streptococcus Mutans Count
Impact of Maternal Xylitol Consumption on Mutans Sterptococci
The study was designed to determine whether maternal xylitol consumption through regular chewing of xylitol gums can affect the salivary mutans streptococci (MS), dental caries, and dental plaque levels of their children.
- Trial name
- NCT02036151
- Testing
- xylitol, fluoride varnish application
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Caries
Effective Fluoride Concentration In Toothpaste For Dental Caries Prevention
to identify the Effective Fluoride Concentration In Toothpaste For Dental Caries Prevention after 18 months of randomized controlled trial.
- Trial name
- DMFT (NCT02016001)
- Testing
- toothpaste 1 with maximum fluoride concentration, toothpaste 2 with 1000 ppm of fluoride
- Where
- Pakistan
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Dental Caries
Effectiveness of Fluoride Varnish in the Prevention of Early Childhood Caries: A Randomized Controlled Trial
Triple-blind randomized controlled trial with two parallel arms conducted between 2012 and 2014. Children 2-3 years old, from 28 rural public preschools, located in low socioeconomic areas of Chile were invited to participate.
- Trial name
- NCT02742038
- Testing
- Fluoride varnish plus education
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Caries Prevention
Comparing Bond Strength,Microleakage and Clinical Performance of Three Pit and Fissure Sealants
The aim of the study is :- 1. To evaluate and compare the microleakage of three different fissure sealants(resin-based Clinpro sealant, Moisture tolerant resin-based Embrace WetBond sealant and glass ionomer Fuji Triage sealant)…
- Trial name
- NCT04272866
- Testing
- Clinpro sealant, Embrace wetbond sealant, Triage sealant
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sarah Emad Ali El-Din
Dental Caries Class II, Dental Caries in Children
Arrest of Proximal Caries Using Orthodontic Bands and Glass Ionomer Cement
The purpose of this study is to evaluate the efficacy of using orthodontic bands with glass ionomer cement to arrest or reverse interproximal lesions as a preventive treatment compared to monitoring and oral hygiene.
- Conditions
- Dental Caries Class II, Dental Caries in Children, Dental Caries on Smooth Surface Limited to Enamel
- Trial name
- NCT04538963
- Testing
- Orthodontic Band affixed with Glass Ionomer Cement
- Where
- 2 sites in United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin