Clinical trials: Carious Lesion
Dental Caries in Children, Anesthesia, Local
Efficacy of Ethyl Chloride Topical Anesthesia Application on the Pain Perception During Intra-oral Injections in Children in Comparison to Benzocaine Gel.
The goal of this single-blinded randomized controlled trial is to compare pain perception during buccal infiltration using indirect EC spray and topical anesthesia and BC 20% topical gel, among seven to 10-year-old school…
- Conditions
- Dental Caries in Children, Anesthesia, Local, Injection Site Discomfort
- Trial name
- NCT06011005
- Testing
- Ethyl Chloride spray (group A), Benzocaine gel 20% (group B)
- Where
- United Arab Emirates
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Dental Caries on Smooth Surface Limited to Enamel, Tooth Demineralization
Resin Infiltration and Fluoride Varnish Lesion Arresting Efficacy on Non-cavitated Proximal Lesion
Protection of dental hard tissues is one of the most important points of cariology. For this purpose, oral hygiene training (effective brushing and motivation), non-invasive approaches such as flouride varnish applications and…
- Conditions
- Dental Caries on Smooth Surface Limited to Enamel, Tooth Demineralization, Dental Caries, Dentistry, Operative
- Trial name
- NCT05202665
- Testing
- ICON DMG Resin Infiltration (micro-invasive approach), ClinproTM White Varnish, 3M ESPE Fluoride Varnish (non-invasive approach)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Tooth Diseases
Comparative Evaluation of an Alkasite-based Restorative Material and Two Different Resin Composites
The clinical performance of an an alkasite-based restorative material and two different resin composites will be evaluated and compared in non-carious cervical lesions.
- Trial name
- NCT06375837
- Testing
- an alkasite-based restorative material, hybrid resin composite, a highly filled flowable resin composite
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries, Parents
Assessment of the Age, Reasons, Oral Health Status and Dental Treatment Needs of Children in Their First Dental Visit
to asses the age, reasons, oral health status and dental treatment needs of children in their first dental visit.
- Conditions
- Dental Caries, Parents, Parenting, Pain
- Trial name
- NCT04183777
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Enamel Hypoplasia
Laser Used in the Treatment of Hypomineralized Occlusal Lesions in Teeth Enamel Affected by MIH
Background: Nowadays an increase in the incidence of teeth affected by molar incisor hypomineralisation (MIH) has been observed.
- Trial name
- NCT03614819
- Testing
- Diode laser group, Glass Ionomer Sealing Group
- Where
- Brazil
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Caries in Children
Effectiveness of Silver Diamine Fluoride in Arresting Dental Caries
The present study aims to evaluate, through a controlled clinical randomized study,the effectiveness of silver diamine fluoride in arresting dentin caries lesions in primary molars when compared to atraumatic restorative…
- Trial name
- NCT03063307
- Testing
- Atraumatic Restorative Treatment, Silver Diamine Fluoride
- Where
- Brazil
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Dental Caries, Gingivitis
Interdental Microbiota Among Adolescents
Adolescence remains a period during which tooth decay is still very active. There are few epidemiological studies in adolescents, and the majority of them were young people aged 15 and under.
- Trial name
- MIARC (NCT03700840)
- Testing
- Interdental brushes
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Université Montpellier
Dental Caries in Children, Diet Habit
Maternal Control of the Child's Feeding, Child's Eating Behavior and Early Childhood Caries in Preschoolers
Dental caries in children is considered one of the most prevalent oral diseases of this age group, leading to significant manifestations presenting as pain, interference with feeding, higher risk of developing dental caries in…
- Conditions
- Dental Caries in Children, Diet Habit, Dietary Exposure, Eating Behavior
- Trial name
- NCT06898918
- Where
- Egypt
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries
Caries-preventive Effect of a Dentifrice Containing 5,000 Ppm Fluoride in Orthodontic Patients
AIM: To evaluate the efficacy of daily tooth brushing with high concentrated fluoride dentifrice on white spot lesion (WSL) formation in adolescents during treatment with fixed orthodontic appliances (FOA).
- Trial name
- NCT01768390
- Testing
- toothpaste containing 5,000 ppm fluoride, 1450 GCP
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- University of Copenhagen
Dental Caries
Preventive Regimens With Herbal and Fluoride Toothpaste on Remineralization in High Caries Patients With Initial Lesions
This study will be conducted to assess the effect of different preventive regimens using herbal toothpaste versus fluoride toothpaste on the management of remineralization and caries risk in high caries risk patients.
- Trial name
- NCT04446390
- Testing
- Himalaya complete care toothpaste, colgate cavity protection
- Where
- 2 sites in Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth, Moringa Oleifera
Remineralization Efficacy of Moringa Oleifera Varnish Vs MI Varnish in Initial Carious Lesions Over 6 Months Follow Up: a Randomized Controlled Clinical Trial
This randomized clinical trial aimed to test the remineralization effect of laboratory prepared Moringa Oleifera based varnish compared to MI varnish (CPP-ACP) on incipient carious lesions.
- Trial name
- NCT06905379
- Testing
- Moringa Oleifera, Varnish
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Caries Transmission Prevention in Alaska Native Infants
The purpose of this study is to conduct a community based, randomized control trial to determine if the use of chlorhexidine mouth rinse and xylitol-sweetened chewing gum will reduce the vertical transmission of caries between…
- Trial name
- NCT00067340
- Testing
- Chlorhexidine mouth rinse, Xylitol chewing gum
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Washington
Dental Caries
Sealing Manifest Occlusal Caries Lesions in the Permanent Dentition
The research project "SEAL-DK" is focusing on advantages and disadvantages of two treatment strategies: non-invasive fissure sealing and invasive restorative treatment of manifest occlusal caries lesions in permanent teeth in…
- Trial name
- SEAL-DK (NCT02573090)
- Testing
- Non-invasive resin based fissure sealing, Invasive resin based restoration
- Volunteers
- 521 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Caries
Er:YAG Laser for Dental Cavity Preparation
The goal of this clinical trial is to compare Er:YAG laser cavity preparation with conventional rotary instruments in adults who have permanent premolars planned for extraction as part of orthodontic treatment.
- Trial name
- NCT07831720
- Testing
- Er:YAG Laser, Conventional Rotary Cavity Preparation
- Where
- Vietnam
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ho Chi Minh City Odonto-Stomatology Hospital
Mowat-Wilson Syndrome, Dental Caries
Oral Health, Dento-facial Condition and OHRQoL in Subjects With Mowat-Wilson Syndrome: an Epidemiologic Study.
Mowat-Wilson Syndrome (MWS) is a rare syndrome characterized by the presence of facial gestalt and delayed psychomotor development, variably associated with intellectual disability, epilepsy, Hirschsprung's disease (HSCR) and…
- Conditions
- Mowat-Wilson Syndrome, Dental Caries, Periodontal Diseases, Sleep Related Breathing Disorder
- Trial name
- ORALMOWAT26 (NCT07476417)
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- University of Milan
Dental Caries
Efficacy of Sealing Molars: Split-mouth Randomized Clinical Trial
The sealing of fossae and fissures is an effective procedure in preventing occlusal caries lesions. However, there are gaps regarding its efficacy in the treatment of initial enamel lesions.
- Trial name
- NCT03819868
- Testing
- High cost, Low Cost
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Dental Caries
Oral Health Knowledge and Caries Experience in Adults
This cross-sectional study assessed the level of oral health knowledge and its relationship with caries experience, independently of age and sex, in adult patients attending a university dental clinic in Gran Canaria (Spain).
- Trial name
- NCT07881380
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Las Palmas de Gran Canaria
Universal Adhesive
HEMA-free Universal Adhesives for Restoring Non-carious Cervical Lesions
because of the recent introduction of universal adhesives, little information is currently available about the bond durability of universal adhesives to various substrates.
- Trial name
- NCT05497583
- Testing
- Acetone based HEMA -free universal Adhesive, Isopropanol based HEMA- free universal Adhesive
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Dental Fluorosis
Anticaries Potential and Fluorosis Risk From Different Fluoride Toothpastes
Fluoride toothpaste has been associated not only with declining dental caries prevalence but also with an increase in dental fluorosis.
- Trial name
- NCT01589991
- Testing
- Toothpaste
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Caries, Dental, Remineralization
Remineralizing Efficacy of Giomer Varnish vs. Fluoride Varnish in Management of White Spot Lesions in Adult Patients
To evaluate the remineralizing capability of biosmart S-PRG barrier coat varnish and its employment in clinical practice
- Conditions
- Caries, Dental, Remineralization, White Spot Lesion
- Trial name
- NCT05306691
- Testing
- Bio-smart Light Cured Protective Shield with bioactive S-PRG (Surface Pre- Reacted Glass ionomer) filler technology (PRG Barrier Coat) by (By SHOFU Inc., Japan).
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
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