Clinical trials: Carious Lesion
Dental Caries, Unsatisfactory or Defective Restoration of Tooth
Clinical Evaluation of a Bulk Fill Resin Composite
The purpose of this clinical trial is to measure the clinical outcomes of Tetric PowerFill Class I and II restorations cured in 3 seconds with the Bluephase PowerCure curing unit.
- Trial name
- NCT04686422
- Testing
- Tetric PowerFill
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Ivoclar Vivadent AG
Caries, Dental
Clinical Performance of an Alkasite-based Restorative Material
The evolution of restorative dental materials and technology has enabled the use of tooth-colored restorative materials in dental restorations, with all dentists hoping for the presence of materials that combine biocompatible…
- Trial name
- NCT06317857
- Testing
- Centio Forte
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cairo University
Clinical Performance
Performance Of Cervical Restorations Using Nitric Acid and Mineral Enriched Adhesive Versus Phosphoric Acid and Universal Adhesive
To evaluate the clinical performance of multifunction Nitric acid etch, mineral enriched adhesive and flowable resin composite liner versus the universal adhesive in etch and rinse mode and regular flowable liner in cervical…
- Trial name
- NCT05928533
- Testing
- clean and boost enamel cleanser of vista apex , RE GEN universal adhesive from vista apex , RE GEN Bio active flowable composite form vista apex
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Cairo University
Dental Caries in Children
SDF Effectiveness on Arresting Caries in Children
Purpose: To assess the clinical effectiveness of silver diamine fluoride (SDF) to control asymptomatic cavitated carious lesions compared to conventional glass ionomer restoration in preschool children.
- Trial name
- NCT05872542
- Testing
- Silver Diamine Fluoride (SDF), Glass Ionomer Restoration (GI), Sodium fluoride varnish with nano-sliver particles (NaF-AgNP)
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Umm Al-Qura University
Class V Non-carious Cervical Dental Lesions
Scotchbond Universal Plus Compared to Scotchbond Universal With Filtek Universal Restorative to Restore Class V NCCLs
This is a prospective, controlled, within-subject, randomized, single-center study comparing Scotchbond Universal Plus (SBU+) and Scotchbond Universal (SBU) adhesives when used with Filtek restorative.
- Trial name
- SBU+ClassV (NCT05361746)
- Testing
- Scotchbond Universal Plus Adhesive, Scotchbond Universal Adhesive
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Specific Learning Disabilities, Dental Caries
Dental Caries and Oral Hygiene Status in Children With Specific Learning Disabilities
This study aims to evaluate dental caries and oral hygiene status in children aged 7-12 years with specific learning disabilities (SLD) and to compare the findings with healthy children.
- Conditions
- Specific Learning Disabilities, Dental Caries, Oral Hygiene
- Trial name
- SLD-OH (NCT07611981)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Dental Caries, Female Infertility
Relationship Between Oral Health Status and Unexplained Female Infertility in Turkish Population
Periodontal diseases and dental caries are initiated by a pathogenic biofilm, in a susceptible host, affecting the tooth periodontium and hard tissues. Its possible association with many biologic systems has been studied.
- Trial name
- NCT03575494
- Testing
- Intraoral and Radiographic Dental Examination
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Dental Caries
Children's Comfort With Isolite and Rubber Dam During Dental Treatment
Effective isolation is essential for successful restorative dental treatment in children because it improves moisture control, treatment quality, and patient safety.
- Trial name
- COMFORT (NCT07718412)
- Testing
- Isolite, Rubber Dam Isolation
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Cumhuriyet University
Neurocognitive Deficit, Quality of Life
WHOle Brain Irradiation or STEreotactic Radiosurgery for Five or More Brain Metastases (WHOBI-STER)
This work aims to evaluate neurocognitive performance, daily activity and quality of life and local control among patients with brain metastasis (MBM) ≥ 5 due to solid tumors treated with Stereotactic RadioSurgery (SRS) or Whole…
- Conditions
- Neurocognitive Deficit, Quality of Life, Activities of Daily Living
- Trial name
- WHOBI-STER (NCT04891471)
- Testing
- Stereotactic RadioTherapy, Whole Brain Irradiation
- Where
- 4 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Mediterranean Institute of Oncology
Caries,Dental
Artificial Intellegence Rivals Digital Bitewing in Detect Secondary Caries
This study uses digital bitewing radiography as a standard for diagnosing proximal secondary caries. Patients will undergo imaging with a parallel technique and fixed settings to ensure high-quality, consistent images.
- Trial name
- NCT06667986
- Testing
- artificial intelligence models (YOLO and Mask-RCNN)
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Effectiveness of Oral Health Education Programs Among School Children, Their Mothers and Teachers in Fayyum: Cohort Study
Cohort study to evaluate the effect of oral health educational program effect on oral health of school children, their mothers and teachers
- Trial name
- NCT05980273
- Testing
- Educational sessions
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Educational Intervention in Preventing Early Childhood Caries
Objective: The aim of this study is to assess the effectiveness of an oral health educative intervention in preventing early childhood caries (ECC).
- Trial name
- NCT01502566
- Testing
- Education Intervention
- Where
- Brazil
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Dental Caries
Nanosilver Fluoride to Prevent Dental Biofilms Growth
This study aims to evaluate the effectiveness of nanosilver fluoride for controlling the growth of S. mutans present in dental plaque of children.
- Trial name
- NSFCT (NCT01950546)
- Testing
- nanosilver fluoride
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pernambuco
Dental Pulp Necrosis, Periapical Diseases
Clinical and Radiographic Success of Calcium Hydroxide-Iodoform Paste Versus Modified Triple Antibiotic Paste for Necrotic Primary Molars in Children
This randomized clinical trial aims to compare the clinical and radiographic success of calcium hydroxide-iodoform paste and modified triple antibiotic paste when used for the treatment of necrotic primary molars in children…
- Conditions
- Dental Pulp Necrosis, Periapical Diseases, Dental Caries, Primary Teeth
- Trial name
- NCT07773805
- Testing
- Calcium Hydroxide, Iodoform, paste, modified triple antibiotic paste
- Volunteers
- 50 people
- Sponsor
- Cairo University
Dental Caries, Pulp Exposure, Dental
Clinical Study Evaluating Solventum™ Vitrebond™ Pulp Protect Liner/Base for Direct Capping of Pulpal Exposure
This research study is looking at the safety and effectiveness of Solventum™ Vitrebond™ Pulp Protect Liner/Base for direct pulp capping (DPC) on permanent teeth that have pulp exposure due either to deep cavities, trauma, or…
- Conditions
- Dental Caries, Pulp Exposure, Dental, Tooth Decay, Dental Decay
- Trial name
- NCT07231237
- Testing
- Vitrebond™ Pulp Protect Liner/Base
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Solventum US LLC
Dental Caries in Children
Comparison Between Amalgam and Hall Technique in Treatment of Carious Primary Teeth
compare between amalgam restoration and hall technique for treatment of decayed primary molars and intervention treatment for decayed primary molars in children, age 3-5 years using split mouth technique in the same child…
- Trial name
- NCT06924203
- Testing
- AmaIgam, Stainless steel
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Suez Canal University
Early Childhood Caries (ECC)
Goal Attainment-Based Parent Education for ECC Prevention
Preventing early childhood caries (ECC) requires improving parental knowledge and behavior, as parents play a critical role in establishing oral and dental health practices during early childhood.
- Trial name
- GAT-ECC (NCT07460271)
- Testing
- Structured Parent Education
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Dental Caries
Intra Oral Appliance (IOA) Model Evaluating the Efficacy of Sensitive Toothpaste
This single-center, randomized, double-blind, three-period crossover in situ study evaluated the enamel remineralization potential and fluoride bioavailability of three dentifrices: a fluoride-free negative control, a positive…
- Trial name
- NCT07419763
- Testing
- Negative Control Toothpaste, Active Comparator, Test toothpaste
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Caries,Dental
Comparison of the Treatment Outcomes of the Conventional Stainless Steel Crown Restorations and the Hall Technique in the Treatment of Carious Primary Molars
Stainless steel crowns have shown high success in restoring carious primary molars over a longer period of time than conventional restorations.
- Trial name
- NCT06597669
- Testing
- Placement of stainless steel crowns on primary molars
- Where
- Vietnam
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hue University of Medicine and Pharmacy
Dental Caries, Pregnancy Related
Oral Health and Pregnancy
The aim of this study is to identify the knowledge, behavior and social representation on dental health among pregnant women. This study could improve, in the future, prevention, treatments and care for them.
- Trial name
- OHAP (NCT04992754)
- Testing
- psychotherapy, lifestyle counseling
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Montpellier
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