Clinical trials: Carious Lesion
Dental Caries
Novel Dental Cements (ALBO-MPCA) in Patients With Caries
Cements on the base of the calcium silicates, like Mineral trioxide aggregate (MTA), and our cement mixture ALBO MPCA, as the object of this clinical trial, have various clinical applications.
- Trial name
- NCT07507136
- Testing
- ALBO MPCA
- Where
- Bosnia and Herzegovina
- Volunteers
- 20 people
- Sponsor
- Albos d.o.o. Beograd
Dental Caries
Partial Removal of Caries Dentines
The aim of this multicenter randomized controlled clinical trial is to evaluate the effectiveness of an alternative treatment for deep caries lesions in Public Health Services.
- Trial name
- PRCD (NCT00887952)
- Testing
- Partial removal of carious dentine, Stepwise excavation
- Where
- 2 sites in Brazil
- Volunteers
- 329 people
- Sponsor
- Federal University of Rio Grande do Sul
Dental Caries
Pharmacokinetics of Advantage Arrest
The study aim is to characterize the kinetics of silver and fluoride after topical application of silver diamine fluoride.
- Trial name
- NCT04184271
- Testing
- 38% silver diamine fluoride
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Advantage Silver Dental Arrest, LLC
Dental Caries
Dietary Analysis for Caries Prevention in Children Using a Computer Software
Children will be recruited from the pediatric dentistry clinic of Marquette University at their first or recall appointment and will be asked to fill a questionnaire regarding their dietary habits.
- Trial name
- NCT02375763
- Testing
- Software instruction
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marquette University
Class V Dental Caries
Clinical Evaluation of Giomer Based Injectable Resin Composite Versus Resin Modified Glass Ionomer in Class V Carious Cavities Over 18-months.
Class V carious lesions will be restored using either Resin modified glass ionomer or Giomer based injectable resin composite.The restorations will be evaluated at baseline and regular recalls of 3 months, 6 months, 12 months and…
- Trial name
- NCT05389163
- Testing
- Giomer based injectable resin composite, Resin modified glass ionomer
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
CAF With or Without CTG for the Treatment of Single Maxillary Gingival Recession With NCCL
This studies evaluate the efficacy of the coronally advanced flap (CAF) with or without connective tissue graft (CTG) for the treatment of single maxillary recession associated to non carious cervical lesion (NCCL).
- Trial name
- NCT03862534
- Testing
- CAF, CAF + CTG
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florence
Caries,Dental
Accuracy of ICCMS Versus Simplified Cariogram
The study aims to compare the validity of the caries risk assessment regarding the comprehensive ICCMs Caries risk and likelihood matrix versus the simplified Cariogram aiming to see if there is a significant difference in the…
- Trial name
- NCT06448884
- Volunteers
- 323 people
- Sponsor
- Kirolos Hisham Nadi Sedek
Dental Caries
Clinical Evaluation and Antimicrobial Effect of Papain Based Chemo-mechanical Caries Removal Agents
Minimally invasive dentistry continues to gain importance, especially in the treatment of permanent teeth with deep caries lesions and immature roots.
- Trial name
- NCT05983900
- Testing
- BRIX3000, papacarie, hand excavation
- Where
- Egypt
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Non-carious Cervical Lesions
Clinical Evaluation of Different Universal Adhesive Systems in Non-carious Cervical Lesions.
The aim of the study is to compare the performance of universal adhesives containing different-solvent-based in the restoration of non-carious cervical lesions (NCCLs).
- Trial name
- NCT04707898
- Testing
- Single Bond Universal, G-Premio Bond
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Okan University
Dental Caries
Xylitol for Caries Prevention in Inner-City Children
The purposes of this study is to determine whether xylitol use in kindergarten school children in addition to oral health education, provision of tooth brush and fluoride paste, fluoride varnish and sealant treatment will reduce…
- Trial name
- NCT01901250
- Testing
- Xylitol gummy bears, Sugar free fiber gummy bears, Oral health education
- Where
- United States
- Volunteers
- 562 people
- Sponsor
- Case Western Reserve University
Dental Caries
Association Between Primary School Children's Speaking Attitudes and Oral Health Indicators
his cross-sectional study aims to evaluate the relationship between primary school children's speaking attitudes and oral health indicators, including dental caries, malocclusion, and tooth loss.
- Trial name
- NCT07271810
- Testing
- Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Ezgi Turkyilmaz
Caries,Dental, Plaque, Dental
Oral Health Education and Message Framing Effect on Oral Health Status of Refugees in Egypt
Refugees, facing forced displacement and often exposed to traumatic experiences, represent a vulnerable population with unique healthcare needs. Oral health is considered a prominent factor that contributes to quality of life.
- Conditions
- Caries,Dental, Plaque, Dental, Gingivitis, Oral Health Quality of Life (OHQoL) Was Assessed
- Trial name
- NCT06649760
- Testing
- Gain and loss framed mobile text messages
- Where
- Egypt
- Volunteers
- 303 people
- Sponsor
- Alexandria University
Dental Caries
Examining the Impact of School-based Dental Screening
This study examines the effectiveness of school dental screening in promoting dental attendance and reducing untreated caries among primary schoolchildren in Riyadh, Saudi Arabia.
- Trial name
- NCT03345680
- Testing
- Referred to a specific hospital for treatment
- Where
- United Kingdom
- Volunteers
- 996 people, healthy volunteers welcome
- Sponsor
- King's College London
Dental Caries, Patient Compliance
A Study to Compare Caries Detection in the Pediatric Population Between the iTero Element 5D System and Bitewing Radiographs
This is a non-significant risk, single site, prospective clinical study. The study will be conducted in the department of pediatric dentistry of the faculty of dental medicine of the Hebrew university, Israel
- Trial name
- NCT05792631
- Testing
- Near infra red imaging
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Substance Use Disorder (SUD), Decayed Teeth
Oral and Dental Health in Substance Dependent Individuals
The goal of this cross-sectional clinical study is to compare the oral health status of individuals with Methamphetamine (MA), Cannabis (THC), and Polysubstance (PSU) use disorders to healthy controls.
- Conditions
- Substance Use Disorder (SUD), Decayed Teeth, Teeth Loss, Teeth Missing
- Trial name
- ODH_SUD (NCT06640712)
- Testing
- Dental caries was assessed using the DMFT index (Decayed, Missing, and Filled Teeth) according to the World Health Organization's caries diagnostic criteria., Substance Use Disorder Diagnosis
- Where
- Turkey (Türkiye)
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Root Caries
Assessment of Arresting Root Surface Caries After the Application of PRG Bioactive Varnish
Guidelines proved that arresting and remineralization of the root surface caries is better than weakening the tooth structure and restoring it.
- Trial name
- NCT05509920
- Testing
- S-PRG barrier coat
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Cavity
Pathogenic Species and Genotypes of Bacterial Diversity in Relation to the Severity of Dental Caries
The primary objective of this study is to estimate the distribution of pathogenic species and genotypes of bacterial diversity in 7 stages ICDAS (International Caries Detection and Assessment System) corresponding to the severity…
- Trial name
- Caries Species (NCT02056262)
- Testing
- Dental cavity evaluation, Saliva sampling, Plaque sampling
- Where
- 3 sites in France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Cariostatic Agents, Mouthwashes
Anticaries Effect of Xylitol,Probiotic and Chlorhexidine Mouth Rinses Among Individuals at High Risk
Dental caries is a localized, post eruptive pathological process involving softening of the hard tooth tissue and proceeding to the formation of cavity.
- Trial name
- AEXPC (NCT04399161)
- Testing
- Chlorhexidine mouthwash, Xylitol, Probiotic
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Dr. Krupa NC
Pulp Exposure, Dental, Deep Dental Caries
Effects of Total and Selective Caries Removal - Requiring or Avoiding Vital Pulp Therapy - on Pulp Vitality and Postoperative Pain in Deep Carious Mature Permanent Teeth: A Split-Mouth Clinical Study
The effect of selective caries cleaning and total caries cleaning on pulp health and post operative pain in teeth with deep caries will be investigated.
- Trial name
- NCT07041905
- Testing
- Total Caries Removal, Selective Caries Removal
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Cukurova University
Dental Caries
DPBRN Longitudinal Study of Questionable Occlusal Caries Lesions
The purpose of this study will allow us to observe and follow the subjects' treatment from DPBRN Prevalence of Questionable Occlusal Caries Lesions Study over a 24 month period.
- Trial name
- NCT01309971
- Where
- 7 sites in United States, Denmark
- Volunteers
- 2,624 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
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