Clinical trials: Carious Lesion
Dental Caries, Artificial Intellegence
Accuracy of an Artificial Intelligence-assisted Diagnostic System for Caries Diagnosis: a Prospective Multicenter Clinical Study
This clinical trial was designed as a prospective, multicenter, multi-reader multi-case (MRMC), superiority, parallel-controlled study. Participants who met the trial criteria and signed the informed consent form were enrolled.
- Conditions
- Dental Caries, Artificial Intellegence, Diagnosis, Machine Learning
- Trial name
- NCT06428344
- Volunteers
- 220 people
- Sponsor
- Zhejiang Provincial People's Hospital
Dental Caries, Pulpotomies Primary Teeth
Ferric Sulfate and Sodium Hypochlorite Pulpotomies in Vital Primary Teeth
This study aims to compare the clinical and radiographic success of two commonly used pulpotomy agents, ferric sulfate (FS) and sodium hypochlorite (NaOCl), in vital primary molars.
- Trial name
- NCT07548008
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Marmara University
Dental Caries
Caries Prevention Effect of S-PRG Filler Incorporated in Denture Base Resins on Edentulous Elderly People
The purpose of this study is to determine whether a novel material of S-PRG fillers containing in a daily-used resin denture base and their capability of fluoride release and recharge to elevate the salivary fluoride level and…
- Trial name
- NCT02460562
- Testing
- S-PRG filler, PMMA resin
- Where
- 3 sites in Thailand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kritirat Kiatsirirote
Preterm Birth, Periodontal Disease
Saving Lives at Birth: Primary Prevention of Periodontal Disease in Relation to Preterm Birth in Malawi
The hypothesis of the investigators' project is that comprehensive primary preterm birth prevention, inclusive of maternal oral health with xylitol chewing gum (the intervention), will reduce the rate of periodontal disease and…
- Conditions
- Preterm Birth, Periodontal Disease, Caries, Dental
- Trial name
- PPaX (NCT02333227)
- Testing
- Xylitol gum
- Where
- United States
- Volunteers
- 10,069 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Pediatric Obesity, Pediatric Dentistry
Oral Health in Children and Adolescents With Obesity and Normal Weight
We aimed to compare the oral health status (dmft/DMFT index, IDCAS-II, BEWE, plaque index, gingival index, probing depth) between normal-weight (NW) and obese (OW) children/adolescents.
- Trial name
- NCT06283602
- Testing
- oral health status
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Dental Pulp Cavity, Root Canal Treatment
Endoscopic Treatment During Endodontic Procedures
The objectives of this Phase I study is to evaluate the safety and effectiveness of the endoscopic endodontic equipment device for root canal assistance treatment as well as to evaluate the ease of use of this device, by a…
- Conditions
- Dental Pulp Cavity, Root Canal Treatment, Endoscopy
- Trial name
- NCT01192607
- Testing
- Endoscopic treatment during root canal treatment
- Where
- Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Barzilai Medical Center
Root Caries, Vertical Root Fracture
Evaluation of Corrective Surgery Versus Dental Implants in Compromised Mandibular Molars
This study seeks to assess the clinical, radiographic, and patient-reported outcomes of hemisection versus implant over a 12 months period, generating robust evidence to guide clinical decision-making and enhance patient care.
- Trial name
- NCT07633834
- Testing
- hemi sectioning
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries
Edulcorants Effect in Caries Risk Schoolchildren
This double-blind RCT aimed to evaluate the effect of sugar-free snacks on caries risk in 6-9 years-old schoolchildren. Considering a 20% difference among groups, the number of subjects needed per group was set in 87.
- Trial name
- STEVIA (NCT03724864)
- Testing
- delivery of snacks
- Where
- Italy
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Oral Health, Dental Caries
The Use of Artificial Intelligence in the Dental X-rays Analysis
This cross-sectional study aims to perform a population-based assessment of the incidence of decay, dental fillings, root canal fillings, endodontic lesions, implants, implant and dental abutment crowns, pontic crowns, and…
- Conditions
- Oral Health, Dental Caries, Periapical Diseases, Tooth Loss
- Trial name
- NCT06258798
- Testing
- Taking a dental X-ray
- Where
- Poland
- Volunteers
- 1,025 people
- Sponsor
- Hospital of the Ministry of Interior, Kielce, Poland
Proximal Dental Caries
Evaluation of Reliability of the Near-infrared Imaging System (VistaCam iX Proxi) in Comparison With Digital Radiographic Findings and ICDAS-II in Detection of Approximal Carious Lesions.
The aim of this study is to evaluate the Clinical performance of the near-infrared imaging system VistaCam iX Proxi in comparison with digital radiographic findings and ICDAS-II in detection of approximal carious lesions.
- Trial name
- NCT03923192
- Testing
- Vistacam, Bitewing radiograph
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Molar Incisor Hypomineralisation, Children
This Study Aims to Evaluate the Effect of Rinsing Off or Blot-drying Silver Fluoride on the Retention of Subsequently-applied Resin- and Glass Ionomer-based Fissure Sealants in Permanent Molars Affected by Molar-Incisor Hypomineralization.
The aim of this study is three-fold: 1. To evaluate the clinical performance of glass ionomer fissure sealants and resin fissure sealants when placed immediately after or one week following the application of silver fluoride on…
- Conditions
- Molar Incisor Hypomineralisation, Children, Dental Caries
- Trial name
- NCT06641011
- Testing
- Immediate restoration (resin- based) after blot-drying silver fluoride application, Immediate restoration (GI- based) after blot-drying silver fluoride application, Immediate restoration (Resin based) after rinsing silver fluoride application
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries
ETT Rotation During Nasal Fiberoptic Intubation
A nasal endotracheal tube (ETT) is routinely placed in children and a fiberoptic scope (FOS) is commonly used for this purpose. Resistance to the passage of ETT is frequently encountered as it is advanced over the FOS for…
- Trial name
- NCT02405546
- Testing
- Pre-Rotated (Group R), No pre-rotation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Dental Caries, Caries Risk
Validation of a Digital Caries Risk Assessment Questionnaire Against the CAMBRA Protocol in an Egyptian Adult Population
This study is designed as a cross-sectional diagnostic agreement study conducted in accordance with the Standards for Reporting Diagnostic Accuracy Studies (STARD 2015) and the Guidelines for Reporting Agreement and Precision of…
- Trial name
- NCT07716254
- Testing
- Digital Caries Risk Assessment
- Where
- Egypt
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Dental Caries, Dental Restoration, Permanent
Comparison of Clinical Performance of Partial Restorations Fabricated With Three-Dimensional Printer and CAD-CAM
The aim of this clinical study is to compare CAD-CAM and 3D restorations in individuals with two hard tissue losses or restorations in their mouths.
- Conditions
- Dental Caries, Dental Restoration, Permanent, Tooth Diseases
- Trial name
- NCT07031856
- Testing
- 3D printer partial crown, Treatment as usual
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Dental Restoration Failure of Marginal Integrity, Dental Caries
Clinical Investigation of a New Bulk Fill Composite Resin in the Restoration of Posterior Teeth
Polymerization shrinkage remains one of the primary disadvantages of composite resin restorative materials (tooth-colored fillings).
- Conditions
- Dental Restoration Failure of Marginal Integrity, Dental Caries, Unrepairable Overhanging of Dental Restorative Materials, Poor Aesthetics of Existing Restoration
- Trial name
- NCT02572570
- Testing
- Filtek Bulk Fill Posterior, Filtek Supreme Ultra
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Dental Caries, Orphaned Children
Evaluation of Oral and Dental Health of Institutionalized Orphan Children Residing in Children's Homes in Turkey
Both dental caries prevalence and periodontal status of children residing in children's homes in Sivas province of Turkey were evaluated.
- Conditions
- Dental Caries, Orphaned Children, Periodontal Index
- Trial name
- NCT06725654
- Testing
- Diagnostic Procedures
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Dentin Hypersensitivity, Non-carious Cervical Lesions, Bioactive Glass Air Polishing, S-PRG
Desensitizing Effect and Tooth Color Change After Using Giomer-based Varnish Versus Bioactive Glass Air Polishing in Treating Cervical Hypersensitive Lesions
This trial is test the dentin hypersenstivity using Giomer based Varnish versus Bioactive glass air polishing system in patients with non-cervical lesions.
- Trial name
- NCT05981625
- Testing
- Giomer varnish containing surface pre-reacted glass fillers
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Diseases
Intensive Preventative Dental Program Pilot Study
Radiation therapy to treat cancer may cause a dry mouth from damage to salivary glands which may increase the risk of cavities on the teeth.
- Trial name
- IPDP (NCT07218068)
- Testing
- Fluoride varnish, Regular Care, Medical Oncology Care Team
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Wake Forest University Health Sciences
Dental Caries, Glass-Ionomer Cement
Heated Glass Ionomer Cement in Primary Molars
Objective: The aim of this study was to assess the influence of heated in the clinical success of proximal high viscosity glass ionomer cement (GIC) restorations in primary molars.
- Conditions
- Dental Caries, Glass-Ionomer Cement, Primary Teeth
- Trial name
- NCT04291872
- Testing
- Glass -Ionomer Cement with /without Led Light Cure
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dental Caries
A Comparative Study of Hall Technique, Modified Hall Technique and Conventional Stainless-Steel Crown Restorations in the Treatment of Primary Molars With Proximal Caries Lesions.
The purpose of this study is to compare the effectiveness of the Hall technique and modified Hall technique to the conventional Stainless-Steel Crown restoration in the treatment of primary molars with dentinal caries with or…
- Trial name
- NCT04822233
- Testing
- Hall Technique (HT), Modified Hall Technique (MHT), Conventional Technique (CT)
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- The University of Texas Health Science Center, Houston
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