Clinical trials: Carious Lesion
Caries, Dental, Cariostatic Agents
Reducing Bacteria That Cause Tooth Decay
The purpose of the study is to determine the effect of a two-step mouth rinsing procedure on reducing the germs (mutans Streptococci) that cause tooth decay.
- Trial name
- NCT03062605
- Testing
- Iodine (Betadine), NaOCL
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Rheumatic Heart Disease, Pregnancy
Dental Anesthesia in Pregnant Women With Rheumatic Heart Disease
The hemodynamic parameters of 31 pregnant women with rheumatic valve disease, undergoing restorative dentistry under local anesthesia with 2% solution of lidocaine, divided in two groups, with (Group LE) and without 1:100,000…
- Conditions
- Rheumatic Heart Disease, Pregnancy, Dental Caries
- Trial name
- NCT00482573
- Testing
- Dental local anesthesia
- Where
- Brazil
- Volunteers
- 31 people
- Sponsor
- University of Sao Paulo
Dental Caries, Restorative Material
Evaluate the Effectiveness of an Experimental Urethane Dimethacrylate Resin Based Dental Composite Material
This double blind randomized controlled prospective clinical trial will compare the clinical success of two tooth colored resin composite dental filling materials - TPH3 (Dentsply Caulk) and an experimental urethane…
- Trial name
- NCT02018822
- Testing
- urethane dimethacrylate, TPH3, Esthet-X HD
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Dental Caries
ETT Rotation During Nasal Fiberoptic Intubation
A nasal endotracheal tube (ETT) is routinely placed in children and a fiberoptic scope (FOS) is commonly used for this purpose. Resistance to the passage of ETT is frequently encountered as it is advanced over the FOS for…
- Trial name
- NCT02405546
- Testing
- Pre-Rotated (Group R), No pre-rotation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Dental Caries
Reliability of Fluorescent Camera and Caries Detection Dye Versus the Visual Tactile Method
1. Three dentinal carious lesions will be chosen in this study and will be in the same patient. 2. Using local anaesthesia and rubber dam, the operative field will disinfected with 1% hypochlorite, and the dentine lesions should…
- Trial name
- NCT03051594
- Testing
- fluorescent camera, caries detector dye, visual tactile assessment
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Composite Resin Plus Connective Tissue Graft.
The aim of the present study is to evaluate the clinical, aesthetic and patient-centered parameters of connective tissue graft associated or not with composite resin for the treatment of gingival recession.
- Trial name
- NCT02423473
- Testing
- Connective tissue graft, Composite resin restoration (Filtek Supreme - 3M)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Dental Caries
Effectiveness of ICCMS in Reducing the Incidence of Dental Caries in Children
The aim of the present study is to evaluate the effectiveness of using the ICCMS (International Caries Classification And Management System)in reducing caries lesions incidence compared to a control group that use different…
- Trial name
- NCT03488056
- Testing
- ICCMS, SESC standard care
- Where
- Brazil
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Oral Health, Dental Caries
Improved Oral Health and Dental Care in Children with Congenital Heart Disease
Background: Congenital heart disease (CHD) is one of the most common congenital anomalies in children. As the risk for endocarditis following bacteraemia is more common during daily oral hygiene routines, such as tooth brushing…
- Trial name
- ORALPEDHEART (NCT03329170)
- Testing
- educational intervention using motivational interviewing
- Where
- Finland
- Volunteers
- 150 people
- Sponsor
- My Blomqvist
Low Back Pain
Soft Tissue Biomechanical Behavior During Acupuncture in Low Back Pain
The goal of this proposal is to test the overall hypothesis that subjects with chronic or recurrent low back pain have an abnormal soft tissue response to acupuncture needling, and that this altered response is associated with…
- Trial name
- NCT00487266
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Deep Dental Caries
Outcomes of Partial Pulpotomy Treatment in Cariously Exposed Teeth
The aim of this clinical trial is to learn how successful Biodentine and Theracal PT dental filling materials are in treating deep tooth decay in adults. It will also provide information about post-treatment pain.
- Trial name
- NCT06802549
- Testing
- Biodentine (calcium silicate-based cement) (Septodont, Saint Maur de Fossés, France), Theracal PT (resin modified calcium silicate-based cement) (Bisco Inc., Schaumburg, IL, USA)
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Firat University
Molar Incisor Hypomineralization, Dental Caries
Prevalence of MIH in Young Adults At Cairo University Dental Hospital and Its Link to Dental Cavities: a Cross-Sectional Study
We are conducting a study to understand how often MIH (Molar Incisor Hypomineralization) occurs and whether it is linked to a higher chance of dental cavities (caries).
- Trial name
- NCT06701552
- Where
- Egypt
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Cairo University
Deep Carious Lesion, Indirect Pulp Treatment
Light Cured Resin Modified Calcium Silicate Versus Light Cured Calcium Hydroxide in Indirect Pulp Treatment of Primary Molars
The objective of this study is to explore if light cured resin modified Calcium silicate could result in better clinical and radiographic success if compared to light cured Calcium hydroxide when used in indirect pulp capping…
- Trial name
- NCT03791255
- Testing
- Calcium silicate liner, Calcium hydroxide liner
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Root Caries, NaF
The Efficacy of Tooth Mouse, SFD and NaF in Caries Activity in Root Caries. A Randomized Clinical Trial
The aim of this study is to summarize the current level of evidence on the prevalence of root caries in elderly population, evaluate the prevalence of root caries in elderly patients living in Canton Bern, Switzerland and to…
- Conditions
- Root Caries, NaF, SDF, Tooth Mousse
- Trial name
- NCT05765058
- Testing
- Group A, Group B, Group C
- Where
- Switzerland
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Bern
Apical Periodontitis, Pulp Disease, Dental
In-Vivo Diagnostic Accuracy and Repeatability of Root ZX3 for Working-Length Determination in Single-Rooted Teeth: Agreement With CBCT and Microscopic Validation
This study evaluated the accuracy and repeatability of the Root ZX3 electronic apex locator for working-length determination in 77 single-rooted permanent teeth.
- Conditions
- Apical Periodontitis, Pulp Disease, Dental, Device Reliability, Device Performance
- Trial name
- NCT07689838
- Testing
- Root ZX3 Electronic Apex Locator
- Where
- Saudi Arabia
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Dental Caries in Primary Molars in Children
Comparison of Smart Burs , Atraumatic Restorative Treatment and Gentle Hand Burs for Caries Removal in Children
This study compared three gentle ways of removing tooth decay in children's primary molars:Gentle hand burs(new hand held rotary instrument used withot electricity),Smart burs (polymer burs used in a slow speed hand piece) and…
- Trial name
- NCT07857785
- Testing
- Gentle Hand Burs, Atraumatic Restorative Treatment, Smart Burs(polymer bur)
- Where
- India
- Volunteers
- 90 people
- Sponsor
- Sathiraju Hema Sai Niharika
Pulpitis, Pain Management
Effects of Topical Anesthesia Approaches on Dental Pain During and After Restorative Management of Dental Caries
The purpose of the Research Study and Overview of Participation: This study will compare different approaches used to prevent pain when giving local anesthesia to numb the teeth while managing dental cavities and decay.
- Trial name
- NCT07379515
- Testing
- Photobiomodulation (PBM)-induced analgesia device using multi-wavelength LED, Medicated analgesia
- Volunteers
- 204 people
- Sponsor
- Dubai Health
Caries, Periodontal Diseases
Third Molar: Caries, Periodontal Disease and Quality of Life
Caries and periodontal disease are chronic diseases of the oral cavity. The incidence of caries and periodontal disease can vary depending on the position of the third molar, The aim of this study was to verify possible…
- Trial name
- NCT04024644
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Caries
Medical Management of Caries in the Primary Dentition Using Silver Nitrate
This pilot trial compares conventional restorations with a new strategy based on the medical management of caries using silver nitrate and fluoride varnish with no restorations.
- Trial name
- NCT02604134
- Testing
- Prophylaxis, Fluoride varnish, Silver Nitrate
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Arwa Owais
Migraine Disorders
TREXIMA and RELPAX Gastric Scintigraphy Inside and Outside a Migraine
An evaluation of tablet disintegration and absorption and gastric transit of sumatriptan and naproxen sodium from a TREXIMA tablet and eletriptan from a RELPAX 40mg tablet.
- Trial name
- NCT00385008
- Testing
- Combination Product (sumatriptan succinate / naproxen sodium), RELPAX(eletriptan) 40mg Tablet
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- GlaxoSmithKline
Dental Caries
Stainless Steel Crowns Versus Bulkfill Composite Resin for Restoring Primary Molars After Endodontic Treatment
The pulp therapy in primary teeth is designed to eliminate the infection and keep the tooth in a functional state until its natural exfoliation.
- Trial name
- NCT03186950
- Testing
- Restoration with Stainless Steel Crowns, Restoration using BulkFill CR
- Where
- Brazil
- Volunteers
- 91 people
- Sponsor
- University of Sao Paulo
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