Clinical trials: Carious Lesion
Dental Pulp Necrosis, Periapical Diseases
Clinical and Radiographic Success of Calcium Hydroxide-Iodoform Paste Versus Modified Triple Antibiotic Paste for Necrotic Primary Molars in Children
This randomized clinical trial aims to compare the clinical and radiographic success of calcium hydroxide-iodoform paste and modified triple antibiotic paste when used for the treatment of necrotic primary molars in children…
- Conditions
- Dental Pulp Necrosis, Periapical Diseases, Dental Caries, Primary Teeth
- Trial name
- NCT07773805
- Testing
- Calcium Hydroxide, Iodoform, paste, modified triple antibiotic paste
- Volunteers
- 50 people
- Sponsor
- Cairo University
Dental Decay
Effect of Dental Treatment on Children's Growth
Severe dental decay affects children physically, emotionally, socially and thereby impacts on their quality of life. Evidence from developed countries showed that children with severe dental decay weighed less than their peers…
- Trial name
- NCT01243866
- Testing
- comprehensive dental treatment, Only emergency dental treatment
- Volunteers
- 86 people
- Sponsor
- King Fahad Armed Forces Hospital
Caries, Dental
Effect of Pulpotomy Using TheraCal Versus MTA on Survival Rate of Cariously-Exposed Vital Permanent Molars
Objective: To assess which is the most efficient pulpotomy medicament on tooth survival in patients with a cariously-exposed vital young permanent molar regarding: absence of postoperative pain, sinus or swelling, internal/…
- Trial name
- NCT03119779
- Testing
- MTA-Anglus, TheraCal
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Anxiety in Children, Dental Pain
Immersive Virtual Reality for Pain and Dental Anxiety During Pediatric Restorative Treatment
This study evaluated whether immersive virtual reality (VR) can help reduce pain and dental fear and improve behavioral cooperation in children undergoing restorative dental treatment.
- Conditions
- Dental Anxiety in Children, Dental Pain, Virtual Reality, Distraction
- Trial name
- VR-PED (NCT07781254)
- Testing
- Immersive Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- University of Gaziantep
Dental Caries, Early Childhood Caries (ECC)
This Feasibility Study Will Evaluate the Study Protocols for Treatment and Follow-up Controls of Primary Molars With Caries in Children Treated With Stainless Steel Crowns or Conventional Fillings. Treatment Success and Potential Failures Will be Followed at 3, 6 and 12 Months Post Treatment.
The goal of this feasibility study is to evaluate the study protocols of a future larger clinical study. In this study children, aged 3-7 years, with caries lesions in their primary molars will be treated with stainless steel…
- Trial name
- HALL-FIT (NCT07882745)
- Testing
- Stainless steel crowns, Conventional fillings
- Where
- 2 sites in Sweden
- Volunteers
- 100 people
- Sponsor
- Marie Norman
Dental Caries
DPBRN Longitudinal Study of Repaired or Replaced Dental Restorations
The purpose of this study is to assess the quality and expected lifespan of fillings recorded in the DPBRN "Reasons for replacement and repair of dental restorations" study, and the factors affecting how long the fillings last.
- Trial name
- NCT01201395
- Where
- 7 sites in United States, Denmark
- Volunteers
- 9,813 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
Dental Restoration Failure of Marginal Integrity, Dental Caries
Clinical Investigation of a New Bulk Fill Composite Resin in the Restoration of Posterior Teeth
Polymerization shrinkage remains one of the primary disadvantages of composite resin restorative materials (tooth-colored fillings).
- Conditions
- Dental Restoration Failure of Marginal Integrity, Dental Caries, Unrepairable Overhanging of Dental Restorative Materials, Poor Aesthetics of Existing Restoration
- Trial name
- NCT02572570
- Testing
- Filtek Bulk Fill Posterior, Filtek Supreme Ultra
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Acute HIV Infection
Effects of Intensive cART During Acute/Early HIV Infection
This trial will investigate the efficacy and safety of intensified antiretroviral treatment that includes raltegravir and maraviroc during the early stages of HIV infection.
- Trial name
- NCT01154673
- Testing
- raltegravir, maraviroc, emtricitabine 200mg /tenofovir 300mg
- Where
- 2 sites in Canada
- Volunteers
- 32 people
- Sponsor
- University of Toronto
Caries,Dental
Microbial Sampling of Carious Dentin
The School of Dentistry is seeking to determine whether viable microorganisms remain within tooth structure after conventional, mechanical removal of areas of tooth decay, prior to placement or replacement of tooth restorations…
- Trial name
- NCT04011605
- Testing
- Biological Sample of Carious Dentin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Utah
Dental Caries in Children
Isolation of the Operative Field Influences the Survival Rate of Composite Restorations
The aim of this study was to evaluate the survival of direct composite resin restorations in primary molars using different methods of isolation of the operative field: absolute isolation (local anesthesia, use of dental clamp…
- Trial name
- IsolationC3 (NCT03733522)
- Testing
- Rubber dam isolation, Relative isolation
- Where
- Brazil
- Volunteers
- 93 people
- Sponsor
- University of Sao Paulo
Dentin Caries
Evaluation of the Remineralizing and Antibacterial Effect of Natural Versus Synthetic Materials on Deep Carious Dentin
The present study will be performed to evaluate: 1. The remineralizing effect of natural materials versus synthetic materials on deep carious dentin after selective caries removal. 2.
- Trial name
- NCT04145102
- Testing
- hesperidine, propolis, silver diamine fluoride
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries
European Study on Three Different Approaches to Managing Class 2 Cavities in Primary Teeth
The purpose of this randomized clinical trial is to compare the clinical effectiveness of three treatments involving different caries management strategies (conventional restorations, Hall technique, and Non-Restorative Caries…
- Trial name
- NCT01797458
- Testing
- Hall Technique, Non-Restorative Caries Treatment, Conventional Restoration
- Where
- 3 sites in Germany, Lithuania and 1 more
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Carious Teeth
Evaluation of Partial Versus Complete Pulpotomy in Carious Immature Molars Permanent Teeth Using Bioceramic Material
One of our major concerns and daily challenges is the management of carious immature permanent teeth, also known as young permanent teeth while preserving the vitality of the dental.
- Trial name
- NCT06101550
- Testing
- partial pulpotomy, Complete pulpotomy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Root Caries
Assessment of Arresting Root Surface Caries After the Application of PRG Bioactive Varnish
Guidelines proved that arresting and remineralization of the root surface caries is better than weakening the tooth structure and restoring it.
- Trial name
- NCT05509920
- Testing
- S-PRG barrier coat
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Cairo University
Preschool Children, Dental Caries in Primary Teeth
A Comparison of Teledentistry vs Clinical Examination for Treatment Needs Assesment
Dental caries is one of the most common chronic diseases in children and may require complex dental treatment, especially in preschool-aged children.
- Trial name
- NCT07625982
- Testing
- Tele- dentistry intraoral exam
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Dental Caries
Effectiveness of ART and Conventional Treatment - Practice-based Clinical Trial
Background: Dental caries is still a public health problem among Brazilian children and doubts still exist regarding the most effective restorative technique.
- Trial name
- NCT02568917
- Testing
- Atraumatic Restorative Treatment - Ketac Molar Easy Mix, Conventional Restoration - Composite Resin (Bulk Fill)
- Where
- Brazil
- Volunteers
- 800 people
- Sponsor
- University of Sao Paulo
Dental Caries, Pulpotomy
Comparison of Clinical Success of Stainless Steel Crowns and Zirconia Crowns in Primary Molars
Evaluation and understanding of clinical success, parental satisfaction and effects on periodontal tissues are the main expected benefits of prefabricated zirconia crowns and prefabricated stainless steel crowns.
- Trial name
- NCT06685640
- Testing
- prefabricated stainless steel crowns, prefabricated zirconia crowns
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Non-carious Cervical Lesions
Deproteinization as a Coadjuvant in Dentin Adhesion of Noncarious Cervical Lesions
This study will verify the effect of the application of a substance (10% sodium hypoclorite -NaOCL) in dentin on noncarious cervical lesions, with the aim of increasing the longevity of the restorations performed in this type of…
- Trial name
- NCT03086720
- Testing
- Sodium hypochlorite, Water
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Class I Dental Caries
Clinical Evaluation of Bioactive Restorative Materials
The objectives of this study are to evaluate and compare the biofilm inhibition and re-mineralizing potential at tooth restoration interface and their 2-year clinical performance in class I cavities.The patients will be selected…
- Trial name
- NCT07003360
- Testing
- application of beautiful blukfill II shofu composite, application of Ivoclar vivadent bulkfill composite, application of Predicta bulk fill composite
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mansoura University
DENTAL CARIES
Incidence of Caries in Smoking and Smokeless Tobacco
The following observational study evaluates incidence of caries in smoking and smokeless tobacco based on habit history by clinical examination and DMFT index.
- Trial name
- ICSSLT (NCT02767050)
- Where
- India
- Volunteers
- 613 people, healthy volunteers welcome
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
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