Clinical trials: Carious Lesion
Nutrition Disorders in Old Age, Caries,Dental
LifE Style, Nutrition and Oral Health in Care Givers (LENTO)
The LENTO study sample includes the caregivers and their clients living in eastern Finland. The aims of this study are 1. to study the nutritional status, oral health, coping, functional capacity and quality of life 2.
- Conditions
- Nutrition Disorders in Old Age, Caries,Dental, Dentures, Oral Mucositis
- Trial name
- NCT04003493
- Testing
- Nutrition and oral health intervention
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Dental Caries in Children
Efficacy and Safety Evaluation of Anti-Caries Varnish
The purpose of the study is to determine the efficacy \& safety of Advantage Anti-Caries Varnish for primary prevention. The objectives are: 1) To determine if Advantage Anti-Caries Varnish (test varnish) is superior to an active…
- Trial name
- NCT04947527
- Testing
- Test varnish
- Where
- United States Minor Outlying Islands
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Advantage Silver Dental Arrest, LLC
Dental Caries
DPBRN Assessment of Caries Diagnosis & Caries Treatment
The purpose of this study was to determine what methods Dental PBRN dentists use for diagnosis, prevention, and treatment of dental decay.
- Trial name
- NCT00526422
- Testing
- Dental Preventive
- Volunteers
- 532 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
Periodontitis, Dental Caries
Comparison of Topical Analgesic With Saline Rinses in Post Extraction Healing
The aim of this study is to determine the beneficial effect of mouth rinses, both topical analgesic and saline regimens as an adjuvant therapy in the presence of standard prescription of post-operative pain killers on the…
- Conditions
- Periodontitis, Dental Caries, Hypertension
- Trial name
- NCT02921165
- Testing
- analgesic mouth rinses (dissolved Aspirin), Normal saline rinses.
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Dental Caries
Phase 2, Safety & Microbiology Study of C16G2 in Multiple Oral Gel &/or Mouth Rinse Doses to Healthy Adults
The focus of the study is to evaluate the safety of multiple study drug administrations and the study drug selectively reducing or eliminating a specific bacteria in the mouth.
- Trial name
- NCT02044081
- Testing
- C16G2 Rinse, C16G2 Gel
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Armata Pharmaceuticals, Inc.
Root Caries, Antihypertensive Drugs
Effect of Hypertensive Drugs on Root Caries Among Senior Patients in Cairo University
The aim of this analytical cross-sectional study study is to evaluate the prevalence of root caries in senior patients of both genders age of 50 to 70 years old, taking antihypertensive drugs attending the Cairo University Dental…
- Trial name
- NCT06709352
- Testing
- non
- Where
- Egypt
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Dental Restoration Failure
Effect on Placement Tecnique of Bulkfill Composite
The objective of this study was to evaluate the clinical performance of a bulk-fill composite resin (3M ESPE Filtek Bulk Fill, St Paul, MN, USA) in restorations placed in occlusal cavities by comparing different placement…
- Trial name
- NCT07673952
- Testing
- bulk tecnique, incrementally technique
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries
Is Biodentine, as Successful as, Mineral Trioxide Aggregate
: A split-mouth controlled clinical trial was carried out on 21 healthy, three to seven years old children, with 42 pairs (84 molars) of contralateral mandibular primary molars indicated for pulpotomy.
- Trial name
- NCT03686475
- Testing
- Biodentine, MTA pulpotomy
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries,Dental
CATCH Healthy Smiles:An Elementary School Oral Health Intervention Trial
The purpose of this study is to clinically evaluate the effects of a school-based behavioral intervention, CATCH Healthy Smiles, to reduce the risk of dental caries in a cohort of kindergarten through 2nd grade (K-2) children…
- Trial name
- NCT04632667
- Testing
- Comparison School Group, Intervention School Group
- Where
- United States
- Volunteers
- 1,084 people
- Sponsor
- The University of Texas Health Science Center, Houston
Dental Caries
A Study to Evaluate the Safety and Microbiology of C16G2 Varnish Administered in Multiple Doses to Dental Subjects
The purpose of this single-blind study is to evaluate whether C16G2 Varnish administered in multiple doses can effectively kill the bacteria in the oral cavity that cause dental caries.
- Trial name
- NCT03004365
- Testing
- C16G2 Varnish
- Where
- 3 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Armata Pharmaceuticals, Inc.
Poliomyelitis
Duration of IPV Priming and Antibody Decay
This is an open-label randomized phase IV clinical trial assessing immunogenicity of poliovirus vaccines.Participants will be enrolled at 6 weeks of age and followed to 18 months of age.
- Trial name
- NCT03202719
- Testing
- Bivalent oral poliovirus vaccine (bOPV) at 6,10 and 14 weeks of age, Inactivated poliovirus vaccine (IPV) at 14 weeks and 18 months of age, Inactivated poliovirus vaccine (IPV) at 14 weeks, 18 weeks and 18 months of age
- Where
- 2 sites in Bangladesh
- Volunteers
- 1,645 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Oral Health, Dental Caries
The Use of Artificial Intelligence in the Dental X-rays Analysis
This cross-sectional study aims to perform a population-based assessment of the incidence of decay, dental fillings, root canal fillings, endodontic lesions, implants, implant and dental abutment crowns, pontic crowns, and…
- Conditions
- Oral Health, Dental Caries, Periapical Diseases, Tooth Loss
- Trial name
- NCT06258798
- Testing
- Taking a dental X-ray
- Where
- Poland
- Volunteers
- 1,025 people
- Sponsor
- Hospital of the Ministry of Interior, Kielce, Poland
Clinical Performance
Clinical Performance of Nano Fiber Reinforced Versus Conventional Nano Hybrid Composite in Restoring Premolars
In patients that need composite restorations in a compound proximal carious lesions in premolars, will the clinical performance of nano fiber reinforced resin composite restorations have similar results compared to those restored…
- Trial name
- NCT05808075
- Testing
- NovaProTM Fill Universal Dental Composite
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Cervical Caries
Clinical Performance of High Viscous Glass Ionomer Cervical Restorations With Silver-Modified Atraumatic Restorative Technique (SMART) Versus Conventional Treatment in Elderly Cancer Patients. (A 12-month Randomized Clinical Trial)
This study will evaluate the clinical performance of glass ionomer cervical restorations placed using the Silver-Modified Atraumatic Restorative Technique (SMART) compared with conventional restorative treatment in elderly cancer…
- Trial name
- NCT07803757
- Testing
- Silver Diamine Fluoride (SDF, 38%), Conventional Tooth Preparation, High-Viscosity Glass Ionomer Cement
- Volunteers
- 30 people
- Sponsor
- Cairo University
Dental Caries
Effect of Silver Diamine Fluoride Application on Oral Microbiome of Healthy Pediatric Patient
This clinical trial aims to learn more about the working mechanism of an antimicrobial agent used to manage dental caries, especially in young, uncooperative children.
- Trial name
- NCT06699199
- Testing
- Silver diamine Fluoride 38%, Silver diamine fluoride- potassium iodide
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- King Abdulaziz University
Deep Dental Caries
Randomized Clinical Trial for Primary Molar Pulpotomy, Biodentine Vs Formocresol-ZOE
This is a RCT that will compare the clinical and radiographic success of pulpotomies on primary molars between the traditional technique (Formocresol/ZOE) and the new technique with Biodentine.
- Trial name
- NCT02201498
- Testing
- Pulpotomies with Formocresol/OZE and Biodentine
- Where
- Canada
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Non-carious Cervical Lesions
Chlorhexidine as Coadjuvant in Dentin Adhesion of Noncarious Cervical Lesions
This study aims to evaluate the effect of chlorhexidine digluconate (CRX) application in etched dentin on the retention of noncarious cervical lesions restorations.
- Trial name
- NCT01947192
- Testing
- Treatment with chlorhexidine, Water pre-treatment
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Root Caries, Vertical Root Fracture
Evaluation of Corrective Surgery Versus Dental Implants in Compromised Mandibular Molars
This study seeks to assess the clinical, radiographic, and patient-reported outcomes of hemisection versus implant over a 12 months period, generating robust evidence to guide clinical decision-making and enhance patient care.
- Trial name
- NCT07633834
- Testing
- hemi sectioning
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Root Caries
36-Month Clinical Performance of Different Restorative Materials in the Treatment of Root Caries Lesions
This is a split-mouth, randomized clinical study that evaluating the 36-month performance of different restorative materials in the treatment of root caries lesions.
- Trial name
- NCT03722758
- Testing
- Spectrum TPH3, Riva LC
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries, Probiotics
Effect of Probiotics on Oral Homeostasis During Sugar Stress
The present study is a double-blinded randomized clinical trial with a duration of 28 days.
- Conditions
- Dental Caries, Probiotics, Gingivitis
- Trial name
- NCT05073393
- Testing
- Sugar stress
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
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