Clinical trials: Carious Lesion
Early Childhood Dental Caries
Development and Evaluation of a Medical Intervention for Early Childhood Caries
This study aimed to evaluate the effect of three forms of continuing medical education (CME) on provision of preventive dental services to Medicaid-enrolled children by medical personnel in primary care physician offices.
- Trial name
- IMB-RCT (NCT00464009)
- Testing
- Continuing medical education
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Caries; Dentin, Dental Caries
Clinical Performance of Restorative Materials in Primary Teeth
The purpose of this study is to evaluate and compare the clinical performance of dental restorative materials in Class II cavities of primary molar teeth
- Trial name
- NCT03037814
- Testing
- Compomer, RMGIC, Giomer
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries
Effectiveness of Fluoride Varnish in the Prevention of Early Childhood Caries: A Randomized Controlled Trial
Triple-blind randomized controlled trial with two parallel arms conducted between 2012 and 2014. Children 2-3 years old, from 28 rural public preschools, located in low socioeconomic areas of Chile were invited to participate.
- Trial name
- NCT02742038
- Testing
- Fluoride varnish plus education
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Dental Caries
The Incidence of IV Fluid Over-administration in Pediatric Dental Surgeries When Infusion Pumps Are Employed
A prospective, analyst-blinded, randomized control trial to assess the incidence of intravenous (IV) fluid over-administration in the setting of pediatric dental surgeries.
- Trial name
- NCT03312452
- Testing
- Hospira plum pump, Gravity drip device
- Where
- Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Post Dental Restoration, Caries, Dental
Clinical Performance of Two Bulk-Fill Composite of Posterior Restorations
To minimize the effects of polymerization shrinkage in the restorative treatment, there are new composites called Bulk- Fill which the companies has developed this composites for example Tetric N Ceram(Ivoclar-Vivadent) and…
- Trial name
- NCT03230604
- Testing
- Filtek Bulk Fill Composite and Tetric N Ceram Bulk Fill Composite, Z 350 Xt Composite
- Where
- Chile
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Andres Bello
Decay, Dental, Caries Class II
Clinical Performance of Short Fiber Reinforced Flowable Resin Composite Restorations 2y RCT
Clinical performance of short fiber reinforced flowable resin composite restorations versus conventional resin composite restorations will be tested in posterior teeth (2y randomized clinical trial).
- Trial name
- NCT04720638
- Testing
- Short fiber reinforced flowable resin composite restorations, Conventional resin composite restoration
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
The Tayside Brushing Study - Adult Follow up
Historically dental health of Scottish children had been poor for many years. Evidence form clinical trials of fluoride toothpaste identified a route to improving prevention.
- Trial name
- NCT02623283
- Testing
- No intervention given
- Where
- United Kingdom
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- NHS Tayside
Demineralization, Remineralization
Clinical Study to Evaluate the Anti-cavity Efficacy of Three Dentifrices: An In Situ Model
Clinical study to evaluate the anti-cavity effectiveness of three dentrifices using an intra-oral enamel Demineralization and Remineralization In-Situ Model.
- Conditions
- Demineralization, Remineralization, Dental Cavity, Enamel Lesions
- Trial name
- NCT07134231
- Testing
- Fluoride free toothpaste in a chalk base, Fluoride Toothpaste, Fluoride free toothpaste in a PCC/RNCC base
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Incipient Interproximal Caries
Can SAP P11-4 Affect The Appearance of Interproximal Cavities on an X-ray in a Military Population
The primary objective of the protocol is to learn about how SAP P 11-4 (produced commercially as Curodont products) can be used in a military population to treat incipient dental caries, or developing cavities that are still…
- Trial name
- NCT07829328
- Testing
- 0.05% Sodium Fluoride with Self-Assembling Peptides
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tripler Army Medical Center
Dental Caries, Unsatisfactory or Defective Restoration of Tooth
Clinical Evaluation of a Bulk Fill Resin Composite
The purpose of this clinical trial is to measure the clinical outcomes of Tetric PowerFill Class I and II restorations cured in 3 seconds with the Bluephase PowerCure curing unit.
- Trial name
- NCT04686422
- Testing
- Tetric PowerFill
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Ivoclar Vivadent AG
Dental Caries, Teeth Loss
Impact of the Radiographic Examination on Diagnosis and Treatment Decision of Caries Lesions in Primary Teeth
Radiographs have been used to aid dentists in detecting the presence of cavities in the deciduous teeth of children. This procedure is globally recommended because the conventional clinical examination usually overlooks some…
- Conditions
- Dental Caries, Teeth Loss, Quality of Life
- Trial name
- CARDEC-1 (NCT02078453)
- Testing
- Dental treatment
- Where
- Brazil
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Caries
Teledentistry Mobile Photos Versus Conventional Clinical Examination for Dental Caries Diagnosis
Teledentistry is an intervention that can boost chances for the new primary healthcare paradigm, bringing service delivery and accessibility to new levels.
- Trial name
- NCT06661837
- Testing
- Clinical examination and mobile photo
- Where
- Egypt
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Early Caries Lesion
Effect of Ozone Therapy on Remineralization of Initial Caries Lesions in Children
Initial caries lesions can be managed using non-invasive treatment approaches that promote remineralization and prevent lesion progression.
- Trial name
- OZONE-CARIES (NCT07671651)
- Testing
- Ozone Therapy, other
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Neslihan Atmaca
Caries, Dental, Local Anesthesia
Effect of AI-Supported Child-Friendly Communication on Dental Anxiety in Pediatric Patients
This study compares the effects of traditional behavior management techniques and AI-assisted child-friendly communication on dental anxiety, physiological stress, and pain perception during local anesthesia in healthy children…
- Conditions
- Caries, Dental, Local Anesthesia, Inferior Alveolar Nerve Block, Dental Anxiety
- Trial name
- NCT07133919
- Testing
- AI-Assisted Child-Friendly Communication, Traditional Behavior Management Techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Dental Caries
Radiographic Progression of Sealed and Infiltrated Caries Lesions in Vivo
The purpose of this study was to compare with a clinical randomized controlled split-mouth design study the changes in the therapeutic effect of infiltrating versus sealing proximal caries lesions and placebo treatment after 1, 2…
- Trial name
- NCT01417832
- Testing
- Resin infiltration / adhesive
- Where
- Colombia
- Volunteers
- 37 people
- Sponsor
- Universidad El Bosque, Bogotá
Dental Caries, Crowned Posterior Teeth
Hall Technique vs Conventional Technique in Permanent Teeth
The purpose of this study is to evaluate and compare the clinical and radiological performance of stainless steel crowns using conventional and Hall technique on permanent molars
- Trial name
- NCT07100028
- Testing
- SSC crown with Hall technique, SSC with conventional technique
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries in Children
Effectiveness of Silver Diamine Fluoride in Arresting Dental Caries
The present study aims to evaluate, through a controlled clinical randomized study,the effectiveness of silver diamine fluoride in arresting dentin caries lesions in primary molars when compared to atraumatic restorative…
- Trial name
- NCT03063307
- Testing
- Atraumatic Restorative Treatment, Silver Diamine Fluoride
- Where
- Brazil
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Dental Caries
Esthetic Evaluation of Onlay Restorations Constructed From Vita Ambria Glass Ceramics
There is limited data available on VITA AMBRIA glass ceramic , so this study is conducted to investigate the esthetic parameters of this new glass press system.
- Trial name
- NCT05437432
- Testing
- VITA AMBRIA, IPS e.max press
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Gingival Recession, Localized, Tooth Abrasion
Use of a Novel Volume-stable Collagen Matrix (VCMX) in the Treatment of Single Gingival Recession Associated With Non-carious Cervical Lesion Partially Restored
Gingival recessions (GR) are often associated with non-carious cervical lesions (NCCL), resulting, thus, in a combined defect. This mucogingival condition has a different treatment prognosis when compared with a GR without…
- Trial name
- NCT05916716
- Testing
- Restorative procedure, Coronally Advanced Flap (CAF)., Volume-stable collagen matrix (VCMX)
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Dental Caries
SDF vs Fluoride Varnish for Streptococcus Mutans Reduction in Children
This randomized split-mouth clinical trial will compare the effectiveness of 38% silver diamine fluoride (SDF) versus 5% sodium fluoride varnish (FV) in reducing salivary Streptococcus mutans levels in children with bilateral…
- Trial name
- Streptococcus (NCT07181967)
- Testing
- Sodium Fluoride Varnish (5%), Silver Diamine Fluoride (38%)
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Assiut University
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