Clinical trials: Carotenoid
Nutrition Assessment
A Clinical Study to Evaluate the Efficacy of a Nutritional Supplement to Improve Carotenoid Content as Measured by a Non-invasive Hyperspectral Absorption Device
The goal of this clinical trial is to evaluate a nutritional supplement in an otherwise healthy adult population. The main questions it aims to answer are: Do antioxidant carotenoid levels increase in after supplementation as…
- Trial name
- NCT07380438
- Testing
- LifePak Optimum nutritional supplement
- Where
- South Korea
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Pharmanex
Achievement, Weight Change
INTEGRATED CHILDHOOD ACTIVITY AND NUTRITION (ICAN) STUDY
This study is a multi-functional integrated research and education project to prevent losses in academic achievement, cognitive function, and behavioral health among at-risk youth.
- Conditions
- Achievement, Weight Change, Cognition, Fitness
- Trial name
- ICAN (NCT07011602)
- Testing
- 8-week Physical Activity and Nutrition Program
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Stroke, Diabetes Mellitus
Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study
The project is a passive follow-up of the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study cohort. Originally, this was a large, randomized, double-blind, placebo-controlled, 2x2 factorial primary prevention trial…
- Conditions
- Stroke, Diabetes Mellitus, Heart Disease, Cancer
- Trial name
- NCT00342992
- Where
- Finland
- Volunteers
- 29,133 people
- Sponsor
- National Cancer Institute (NCI)
Health Behavior
Evaluation of Changes in Skin Carotenoid Scores in Medical Students Following Dietary Interventions
Skin Carotenoid Scores (SCS) are a biomarker of overall antioxidant status. This study will use Raman Spectroscopy to examine the ability of increased dietary intake of fruits and vegetables to increase SCS in medical students.
- Trial name
- NCT02163928
- Testing
- Food-based intervention; increased fruits and vegetables
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Oxidative DNA Damage
Biological Functions of Carotenoids in Humans
This study will examine the the efficiency fo absorption of major plant pigments, carotenoids, (lutein, beta-carotene and lycopene)and will measure the biological functions of carotenoids in healthy women in response to an 8-week…
- Trial name
- NCT00356252
- Testing
- mixed carotenoids
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tufts University
Primary Intestinal Hypocholesterolemia, Abetalipoproteinemia
CArotenoid in hypoChOlesterolemia
Hypobetalipoproteinemias (HBL) represent a heterogeneous group of disorders characterized by reduced plasma levels of plasmatic lipids (mainly triglycerides, total cholesterol (TC), LDL-cholesterol (LDL-C), and apolipoprotein B…
- Conditions
- Primary Intestinal Hypocholesterolemia, Abetalipoproteinemia, Chylomicron Retention Disease
- Trial name
- CaCo (NCT05208879)
- Testing
- Characterization of carotenoid status and plasma levels of oxidative stress markers in patients (case group only), Characterization, evaluation and comparison of macular pigment density
- Where
- 3 sites in France
- Volunteers
- 10 people
- Sponsor
- Hospices Civils de Lyon
Diabetes Mellitus, Oxidative Stress
Low Dose β-carotene Supplementation Diminishes Oxidative Stress in Type 2 Diabetics and Healthy Individuals
Since diabetes has multiple etiologies and oxidative stress one of the proposed mechanisms, the objective is to determine the effect of supplementation with β-carotene to type 2 diabetics and healthy individuals, on iron…
- Conditions
- Diabetes Mellitus, Oxidative Stress, Iron Metabolism Disorders
- Trial name
- NCT01477112
- Testing
- Betacarotene, Controls. No treatment
- Where
- Venezuela
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Instituto Venezolano de Investigaciones Cientificas
Macular Degeneration
"Night Vision and Carotenoids"
Vision at twilight and night is more difficult and dangerous for the entire population, even more so for the elderly and especially for the elderly with degenerative disease.
- Trial name
- NCT04741763
- Testing
- EyePromise Visual Edge
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- Robert Davis
Bioavailability
Effect of Iron and Zinc Supplementation on B-carotene Bioavailability in Healthy Males
In vitro studies found supplemental levels of iron and zinc to inhibit the micellization and cellular uptake of β-carotene. Here, we investigated this in vivo, in a double-blind 3-arm crossover human trial.
- Trial name
- NCT05840848
- Testing
- Control beta-carotene supplement plus iron Supplement, Control beta-carotene supplement plus zinc Supplement
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Iron Absorption
Effects of Vitamin A and Carotenoids on Iron Absorption
The objective of this study is to investigate the effect of vitamin A and carotenoids on iron absorption in healthy subjects with low and normal vitamin A status.
- Trial name
- NCT01493297
- Testing
- Labeled iron solutions
- Where
- Venezuela
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Healthy Infants
Influence of Inflammation on Micronutrient Status Assessment
Inflammation can influence several biochemical measurements those commonly used to interpret micronutrient status in children. Our primary objective is to investigate the effects of inflammation on several biochemical…
- Trial name
- NCT03801161
- Testing
- Pentavalent vaccine. It is a combination of five different antigens (Hepatitis B (HBV)/ Haemophilus influenzae type b (HiB) / Tetanus-Diphtheria-whole cell Pertussis (TDwP)).
- Where
- 2 sites in Bangladesh
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Carotenoid, Bioavailability
Effect of Meal Patterning on Carotenoid Absorption From Vegetables
The purpose of this research study is to determine how different meal patterns influence the absorption of beneficial plant pigments (carotenoids) from vegetables.
- Conditions
- Carotenoid, Bioavailability, Dietary Modification
- Trial name
- S26 (NCT01856816)
- Testing
- Meal Pattern Treatment A, Meal Pattern Treatment B, Meal Pattern Treatment C
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Purdue University
Black Pepper, Absorption
Effects of Black Pepper on the Absorption of Nutrients in Vegetables
The objective of this project is to determine the extent to which eating black pepper together with vegetables increase the absorption of carotenoids (a class of important nutrients) in the vegetables such as beta-carotene.
- Conditions
- Black Pepper, Absorption, Carotenoid
- Trial name
- NCT03490955
- Testing
- salad dressing (canola oil) and black pepper, salad dressing (canola oil), black pepper
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Nutrient Deficiency, Pregnancy Related
Lutein & Zeaxanthin in Pregnancy - Carotenoid Supplementation During Pregnancy: Ocular and Systemic Effects
This study is designed to test the hypotheses that (1) the third trimester of pregnancy is a period of maternal systemic and ocular carotenoid depletion; (2) prenatal supplementation with 10 milligrams of lutein and 2 milligrams…
- Trial name
- L-ZIP (NCT03750968)
- Testing
- Carotenoid Group, Control Group
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Paul S. Bernstein
Body Weight, Obesity & Overweight
Breastmilk and the Link to Overweight/Obesity and Maternal Diet in the Mother-breastmilk-child Triad
The prospective 5-month follow-up study will involve 150 mother-infant dyads grouped based on maternal baseline BMI category (normal weight, overweight, obesity).
- Conditions
- Body Weight, Obesity & Overweight, Human Milk/Breastfeeding, Body Composition
- Trial name
- BLOOM-Triad (NCT07457515)
- Where
- 4 sites in Canada, Poland
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Warsaw University of Life Sciences
Aging, Well Aging
Age Related Effects Consuming Phaeodactylum Tricornutum
Investigation of the microalgae Phaeodactylum as food with regard to the uptake of omega-3 fatty acids and effects on various blood parameters in relation to age.
- Trial name
- MIA_E (NCT05120791)
- Testing
- microalgae phaeodactylum, From the Microalgae phaeodactylum the extracted beta-Glucan (especially chrysolaminarin), A combination of the vegetable bouillon, the microalgae and the beta-Glucan
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Tuberculosis
The Role of Vitamin D, A, and Beta Carotene in Tuberculosis Patients With Vitamin D Receptor Gene Polymorphism
Recent studies showed that vitamin D and A has an effect in improving sputum conversion in tuberculosis. This study aims to find out the effect of vitamin D 1000 IU and A 6000 IU supplementation on Tuberculosis patients with…
- Trial name
- NCT04593524
- Testing
- vitamin D 1000 IU and A 6000 IU supplementation and nutritional counseling, nutritional Counseling
- Where
- Indonesia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universitas Sumatera Utara
Glaucoma, Glaucoma Eye
Augmented Macular Pigment-containing Nutraceutical and Central Visual Function
The purpose of this study is to prospectively analyze changes in macular pigment optical density and dermal carotenoid levels as they relate to visual field function in patients prescribed a macular pigment-containing medical…
- Conditions
- Glaucoma, Glaucoma Eye, Glaucoma, Open-Angle
- Trial name
- NCT04676126
- Testing
- Lumega-Z, Dorzolamide Hcl 2% Oph Soln
- Where
- United States
- Sponsor
- University of the Incarnate Word
Hypercholesterolemia
Effect of High Stanol Ester Dose on Serum Lipids, Carotenoids and Fat-soluble Vitamins
The aim was to investigate the effects of the consumption of high doses of plant stanol esters on concentrations of serum lipids, carotenoids and fat soluble vitamins.
- Trial name
- maxsta (NCT00698256)
- Testing
- vegetable oil-based spread and oat-based drink (no brand name available)
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marjukka Kolehmainen
Overweight
The Juice Study: Sensitivity of Skin Carotenoid Status to Detect Change in Intake
This study is designed to see if drinking a tomato-based vegetable juice will increase skin carotenoids.
- Trial name
- NCT03202043
- Testing
- High dose vegetable juice, Medium dose vegetable juice, Low dose vegetable juice
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center