Clinical trials: Carotenoid
Postprandial Carotenoid Response
Effect of Co-consuming Different Dietary Protein Sources With Salad on the Bioavailability of Carotenoids
The goal of this clinical trial is to learn if different protein types will affect carotenoid responses in humans when co-consumed with salad.
- Trial name
- NCT07795372
- Testing
- Salad only, Salad + Chicken, Salad + Tuna
- Where
- Singapore
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Absorption, Metabolism and Excretion in Healthy Volunteers, Bioavailability and AUC
Bioavailability Trial
Carrot is a unique vegetable owing to the availability of bioactive compounds polyacetylenes (PA) as well as carotenoids present in it.
- Trial name
- NCT06686004
- Testing
- Carrots
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Age Related Macular Degeneration, Cognition Disorders
The Zeaxanthin and Visual Function Study
To evaluate if supplementation of zeaxanthin (with or without Lutein) is beneficial to patients with early and moderate Atrophic Age Related Macular Degeneration.
- Trial name
- ZVF (NCT00564902)
- Testing
- 3R 3'R Zeaxanthin, Lutein, Lutein and Zeaxanthin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Chrysantis, Inc.
Raman Spectroscopy, Children, Only
The Effect of a Nutrient Dense Food on the Skin CarotenoidLevels of School Age Children
Background: In a previous study, children who consumed a high-carotenoid juice over 8 weeks significantly increased skin carotenoid levels as compared to children who consumed a placebo juice.
- Trial name
- NCT03146715
- Testing
- Feeding trial
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Utah State University
Antioxidant Role of the Lutein in Preterm Newborn
Early Administration of the Lutein/Zeaxanthin in Premature Newborns
Premature birth is the most common cause of mortality, morbidity and disability. Premature infants have a higher risk of developing damage in the eyes (retinopathy of prematurity ROP), in the central nervous system…
- Trial name
- NCT03340103
- Testing
- LUTEIN ofta 0,5 gocce
- Where
- 4 sites in Italy
- Sponsor
- Sooft Italia
Bioavailability of Carotenoids
Human Lycopene and Beta-cryptoxanthin Absorption From Citrus Fruit
The goal of the research study is to measure and compare the absorption of equivalent amounts of beta-cryptoxanthin and Iycopene provided in citrus fruit.
- Trial name
- NCT02348164
- Testing
- Pink grapefruit first followed by tangerines two weeks later, Tangerines first followed by pink grapefruit two weeks later
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Healthy
The MULTINUTRIENT Maize Project: Results of Human Feeding Trial
The main objective of this human trial is the demonstration that β-carotene in fortified maize has good bioavailability as a plant source of vitamin A and that when humans ingest the biofortified product retinol levels are higher…
- Trial name
- MAIZE (NCT02373943)
- Testing
- β-carotene biofortified maize, β-carotene supplemented maize, Normal (non biofortified) maize without added β-carotene
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institut de Recerca Biomèdica de Lleida
Skin Carotenoid Status
Study on Carotenoid-Based Instrumental Index
Nu Skin (China) Daily-Use\&Health Products Co.,Ltd. has developed biophotonic scanners based on Raman spectroscopy, which measures skin carotenoid levels through hand skin scanning.
- Trial name
- NCT07198503
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Sleep Disturbance, Visual Health
Gac Fruit Oil Supplementation for Visual Health and Sleep Quality
This study evaluated the effects of gac fruit oil supplementation on visual health, sleep quality, depressive symptoms, cognitive function, and brain imaging parameters in adults with sleep disturbance.
- Trial name
- NCT07623070
- Testing
- Gac Fruit Oil Capsules
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Yuanpei University of Medical Technology
Healthy
Pharmacokinetics of MCS in Healthy Volunteers
This study is to examine the pharmacokinetics, absorption and serum concentrations of MCS and other components after once-daily oral dosing of MCS.
- Trial name
- MCS-2-US-pk (NCT01003171)
- Testing
- MCS-2 soft-gel capsule
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Health Ever Bio-Tech Co., Ltd.
Diabetes, Diabetic Retinopathy
Diabetic Retinopathy Functional Evaluation Study: Monitoring Carotenoid Vitamins Treatment Using ERG
To evaluate the differences in retinal function as measured by ERG in diabetics with and without retinopathy 2) the ability of the Chromatic Electroretinogram (chERG) to detect changes in global retinal function following…
- Trial name
- NCT04117022
- Testing
- DVS supplementation
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- ZeaVision, LLC
Beta-cryptoxanthin Supplementation
Beta-cryptoxanthin Supplement: Absorption and Function
Beta-cryptoxanthin (BCX) is a naturally occurring member of the carotenoid family, found in a wide range of fruits and vegetables.
- Trial name
- BETA+ (NCT05046457)
- Testing
- Beta-cryptoxanthin (BCX)
- Where
- Singapore
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Cardiovascular Diseases
Increased Access to Fruits and Vegetables for Hypertension in Immigrant Hispanic/Latinx Individuals
The goal of this observational study is to learn about the effect improved access to culturally-appropriate fruits/vegetables has on cardiometabolic markers, specifically systolic blood pressure and markers of adiposity in…
- Trial name
- NCT05802134
- Testing
- Fruit and vegetable supplement, Dietary and chronic disease management education
- Where
- 5 sites in United States
- Volunteers
- 21 people
- Sponsor
- St. Catherine University
Microbiota, Cognitive Function
Effect of Tomato Paste Consumption on the Microbiota-gut-brain Axis in Healthy Adults
Tomatoes and tomato-based products could play an important role in modulating microbiota-gut-brain axis (MGBA) interactions due to their high content of fiber and phytochemicals.
- Conditions
- Microbiota, Cognitive Function, Healthy Lifestyle
- Trial name
- MITOS (NCT05891977)
- Testing
- Intervention A - Tomato paste, Intervention B - Control
- Where
- Spain
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Retinal Drusen, Age-related Macular Degeneration
Evaluation of a New Eye-specific Multivitamin Formula in Participants at Risk of Age-related Macular Degeneration (AMD)
The aim of this study is to evaluate the clinical benefits in visual function from dietary supplementation of the Lumega-Z carotenoid liquid-supplement in participants with drusen and at risk of AMD.
- Conditions
- Retinal Drusen, Age-related Macular Degeneration, Macular Degeneration
- Trial name
- AMD (NCT03946085)
- Testing
- Lumega-Z, AREDS2
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Guardion Health Sciences, Inc.
Idiopathic Juxtafoveal Telangiectasia
The Role of Macular Pigment Carotenoids in the Pathogenesis and Treatment of Macular Telangiectasia Type 2 (MacTel)
Macular telangiectasia type 2 ("MacTel Type 2") is an uncommon eye disorder that results in slow vision loss beginning in middle age.
- Trial name
- NCT01354093
- Testing
- zeaxanthin
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Paul S. Bernstein
Childhood Obesity Pevention, Diet Quality
Healthy Children, Healthy Communities: Effectiveness of a Multilevel Rural Community Engagement Model for Improving Children's Dietary Intake in Family Child Care Homes
The purpose of this study is to find out whether a program called "Healthy Children, Healthy Communities" can help young children in rural areas eat healthier and improve their health.
- Conditions
- Childhood Obesity Pevention, Diet Quality, Feeding Behaviors, Health Behavior Change
- Trial name
- NCT07160530
- Testing
- EAT Family Style, Better Kid Care
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Efficacy and Safety of MCS-2 in the Treatment of Lower Urinary Tract Symptoms
The hypothesis of the study is to examine whether MCS-2 is safe and effective in the treatment of lower urinary tract symptoms suggestive of benign prostatic hyperplasia.
- Trial name
- MCS_LUTS (NCT01002664)
- Testing
- MCS-2
- Where
- Taiwan
- Volunteers
- 272 people
- Sponsor
- Health Ever Bio-Tech Co., Ltd.
Pediatric Population on Second Generation Antipsychotics
Beta-carotene and Oxidative Stress in Pediatric Second Generation Antipsychotic Use
Weight gain, hypertension, high cholesterol and sugar abnormalities in childhood are strongly linked and predict the risk of further complications and early death in adulthood.
- Trial name
- NCT02363816
- Sponsor
- Wayne State University
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Open-Label Extension Study of MCS-2 in the Treatment of Lower Urinary Tract Symptoms (MCS-2-US-c)
This is an open-label extension study of another study protocol, MCS-2-US-a. Subjects who have completed the 12-week treatment and procedures under the protocol MCS-2-US-a will be eligible for this study.
- Trial name
- MCS-2-US-c (NCT01002222)
- Testing
- MCS-2
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Health Ever Bio-Tech Co., Ltd.