Clinical trials: Carotid Arteries
- Condition Carotid Arteries
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Carotid Atherosclerosis
Carotid Risk Prediction (CRISP) Consortium
Develop adverse event prediction and plaque phenotype classification models for patients with known or suspected carotid artery disease.
- Trial name
- CRISP (NCT04448353)
- Testing
- vascuCAP
- Where
- 5 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Elucid Bioimaging Inc.
Carotid Stenosis, Cerebrovascular Accident
Cost-Effectiveness of a Specialized Ultrasound Instrument to Diagnose Carotid Stenosis as a Way to Reduce the Risk of Stroke
Carotid stenosis, a condition in which plaque builds up inside the arteries of the neck and blocks blood flow to the brain, is one common cause of stroke.
- Trial name
- NCT00417586
- Testing
- Specialized Doppler Ultrasound Instrument
- Where
- United States
- Volunteers
- 984 people, healthy volunteers welcome
- Sponsor
- DVX, LLC
Aortic Pulse Wave Velocity
Validation of Optical Device for Aortic Pulse Wave Velocity Measurement
Existing techniques available for capturing reliable aortic pulse wave velocity measurements and estimating aortic stiffness are costly and require technical expertise.
- Trial name
- NCT05400421
- Testing
- System & Method for Monitoring Aortic Pulse Wave Velocity & Blood Pressure
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- VitalSines International Inc.
Hypercholesterolemia, Familial
Carotid IMT (Intima Media Thickening) Study (0524A-041)(TERMINATED)
This is a 105-week clinical study in patients with heterozygous familial hypercholesterolemia on intensive Low Density Lipoprotein-cholesterol (LDL-C) lowering therapy intended to assess the affects of MK0524A on carotid intima…
- Trial name
- ACHIEVE (NCT00384293)
- Testing
- Comparator: niacin (+) laropiprant (MK0524A)
- Volunteers
- 937 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Cardiovascular Disease, Cigarette Smoking
Cardiovascular Disease Biomarkers in Smokers and Moist Snuff Consumers
This cross-sectional study was primarily a cardiovascular disease (CVD) study designed a) to compare selected CVD biomarker data between subjects who were long-term consumers of cigarettes or moist snuff and non-consumers of…
- Trial name
- NCT01692353
- Testing
- Subject's usual brand (UB) tobacco product
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- R.J. Reynolds Tobacco Company
Atherosclerosis, Inflammatory Activity in Carotid Arteries
Effects of Crestor on Inflammation of Atherosclerotic Plaques
The primary aim of this study is to investigate the effect of 40 mg dose of rosuvastatin on carotid plaque inflammation measured with MRI and PET scanning, to evaluate whether these techniques are promising for future proof of…
- Trial name
- NCT00689416
- Testing
- rosuvastatin
- Where
- Sweden
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Cardiovascular Diseases
Evaluation of Atorvastatin Treatment on Carotid Plaque.
The purpose of the study is to evaluate the effect of 18 months treatment with atorvastatin 80mg or atorvastatin 10mg on the carotid vessel plaque morphology, in particular, the effect on evident necrotic lipid rich core of the…
- Trial name
- NCT00343655
- Testing
- Atorvastatin
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Carotid Intima- Media Thickness
A Study to Derive Normative Distribution of CIMT and to Determine Its Correlation With Cardiovascular Risk Factors
This non-interventional, prospective, multi-centric, cross-sectional study is aimed to obtain the distribution of measurements of CIMT in Indian subjects and will involve approx. 30 investigative sites from all over the country.
- Trial name
- Score-India (NCT01551875)
- Where
- 24 sites in India
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Carotid Artery Plaque
99mTc-rhAnnexin V-128 Imaging for Carotid Atherosclerosis
This was a single-center, single-dose, study comprising a Proof of Concept (PoC) part and a subsequent Phase II part. The study was being done to assess the ability of the radiotracer 99mTc-rhAnnexin V-128 to image…
- Trial name
- NCT02667457
- Testing
- 99mTc-rhAnnexin V-128
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Advanced Accelerator Applications