Clinical trials: Carotid Artery Diseases
Migraine
Stimulation of External Carotid Artery Circulation
This study is testing a new approach to help people with migraine headaches. Researchers want to find out if using electrical stimulation to affect blood flow in the external carotid artery is safe and practical for helping…
- Trial name
- MMA-Stim (NCT07402954)
- Testing
- Cadwell Cascade 32 PRO
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Moyamoya Disease
Family-Based Moyamoya Susceptibility and Early Detection
This single-center, prospective, family-based observational cohort study aims to investigate susceptibility to moyamoya disease (MMD) and to develop strategies for early screening in individuals at increased familial risk.
- Trial name
- FAMES (NCT07517354)
- Testing
- 5T High-Resolution MRI
- Where
- China
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Stroke, Ischemic, Stenosis, Carotid
Impact of Significant Carotid Stenosis on Retinal Perfusion Measured Via Automated Retinal Oximetry
Background: Large vessel carotid stenosis represent significant cause of ischaemic stroke. Indication for surgical revascularisation treatment relies on severity stenosis and clinical symptoms.
- Trial name
- NCT06085612
- Testing
- Automated retinal oximetry
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- University Hospital Olomouc
Type 2 Diabetes Mellitus, Carotid Atherosclerosis
Effect of Cilostazol on Carotid Atherosclerosis Estimated by 3D Ultrasound in Patients With Type 2 Diabetes
To investigate the effect of cilostazol compared with aspirin on carotid atherosclerosis in patients with type 2 diabetes mellitus
- Trial name
- NCT03248401
- Testing
- Cilostazol, Aspirin
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Bundang Hospital
Carotid Stenosis
A Study of the Effects of Minocycline on Cognitive Function After Carotid Endarterectomy
The primary aim of this protocol is to investigate a possible new, neuroprotective treatment to prevent cognitive deficits that occur after carotid endarterectomy.
- Trial name
- NCT00401921
- Testing
- Minocycline
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Vertigo, Carotid Artery Diseases
Is Carotid-Vertebral Doppler Ultrasonography Necessary for Patients With Vertigo?
This study will be carried out prospectively on patients who applied to the cardiovascular surgery polyclinic and the carotid-vertebral artery doppler ultrasound due to the vascular problem.
- Trial name
- NCT05196685
- Testing
- Carotid Doppler USG
- Where
- Turkey (Türkiye)
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Abdominal Aortic Aneurysm (AAA), Thoracic Aortic Aneurysm (TAA)
Overlay of 3D Scans on Live Fluoroscopy for Endovascular Procedures in the Hybrid OR
As endovascular procedures become more complex, there is a growing need for 3D image overlay to assist with device guidance and placement.
- Conditions
- Abdominal Aortic Aneurysm (AAA), Thoracic Aortic Aneurysm (TAA), Carotid Stenosis, Visceral Artery Aneurysm
- Trial name
- NCT01480206
- Testing
- Endovascular Aortic Repair (EVAR)
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Carotid Artery Diseases, Regional Anesthesia
Stress Reduction Using Video Googles on Patients Undergoing Vascular Surgery
One treatment option of internal carotid artery stenosis is open surgical endarterectomy. The operation is frequently carried out under regional plexus anesthesia, allowing the patient to remain awake during the procedure.
- Conditions
- Carotid Artery Diseases, Regional Anesthesia, Distress, Procedural
- Trial name
- MEP-VASC (NCT06704230)
- Testing
- video googles
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Augsburg
Head and Neck Cancer, Carotid Artery Stenosis
Carotid Ultrasound to Identify Head and Neck Cancer Survivors With High Cardiovascular Risk After Radiation Therapy
The purpose of this research study is to understand how radiation therapy may affect blood vessels in the neck called the carotid arteries.
- Conditions
- Head and Neck Cancer, Carotid Artery Stenosis, Cardiovascular Complication
- Trial name
- NCT05490875
- Testing
- Carotid ultrasound, Blood draw, Survey
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Wake Forest University Health Sciences
PET/MR, Stroke Ischemic
PET/MR Multimodal Quantitative Analysis of CBF and CMRGlc in Cerebral Ischemia
Research Purpose: This project focuses on clinical research issues in the diagnosis, treatment, and evaluation of patients with cephalic and carotid atherosclerosis.
- Trial name
- PMQIC (NCT07079345)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Carotid Stenosis
CorMatrix ECM for Carotid Repair Following Endarterectomy Registry
Assess device performance data from subjects undergoing patch angioplasty of the carotid artery following carotid endarterectomy using the CorMatrix ECM for Carotid Repair.
- Trial name
- NCT01569594
- Testing
- CorMatrix ECM for Carotid Repair
- Where
- 6 sites in United States
- Volunteers
- 230 people
- Sponsor
- Elutia Inc.
Atherosclerosis
Identification of Genes Expressed in Atherosclerotic Plaque
This study will identify genes and proteins in the blood of patients with atherosclerosis and in that of normal volunteers. The findings will be compared to determine the influence of these substances on the development of…
- Trial name
- NCT00353730
- Where
- 2 sites in United States
- Volunteers
- 69 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Carotid Artery Occlusive Disease
A Comparison of Cognitive Function After Carotid Endarterectomy and Stenting
This study compares cognitive function after carotid endarterectomy and stenting.
- Trial name
- NCT02220595
- Testing
- Carotid endarterectomy vs. carotid stenting
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Baylor College of Medicine
Carotid Stenosis
Co-administration of Dexmedetomidine in Carotid Endarterectomy (CEA)
All neurosurgical patients at the Neurosurgery University Hospital Bern who will be operated for carotid endarterectomy (CEA) are routinely operated in deep anae¬sthesia with suppression of the electrical activity of the…
- Trial name
- NCT04662177
- Testing
- Dexmedetomidine
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Carotid Stenosis
Role of the Type of Carotid Stent and Cerebral Protection on Cerebral Microembolization During Carotid Artery Stenting. A Randomized Study Comparing Carotid Wallstent vs Roadsaver® Stent and Distal vs Proximal Protection.
Stenting is an alternative to traditional surgery in the treatment of carotid stenosis.The intra and/or postprocedural cerebral embolization remains the most frequent complication.
- Trial name
- NCT02915328
- Testing
- Filterwire EZ™, MO.MA Ultra, Stent Roadsaver®
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Centro Cardiologico Monzino
Quadrantectomies, Spinal Fusion
Complementary and Alternative Medicine Interventions in Targeting Pain
This Controlled Randomized Clinical Trial aimed at determining the effectiveness of a modified RR intervention in reducing post-operative pain and psychological symptoms in patients undergoing surgery intervention.
- Conditions
- Quadrantectomies, Spinal Fusion, Carotid Stenosis, Abdominal Aortic Aneurysm
- Trial name
- CAMP (NCT04845334)
- Testing
- RR intervention
- Volunteers
- 128 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Moyamoya, Stroke
The Adult Hemorrhagic Moyamoya Surgery Study
The aim of this study is to investigate whether extracranial-intracranial(EC-IC) bypass surgery could prevent rebleeding and improve neurological function in adult moyamoya with hemorrhagic onset.
- Trial name
- AHMSS (NCT02319980)
- Testing
- Extracranial-intracranial bypass surgery
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Huashan Hospital
Periodontitis, Intimal Medial Thickness of Internal Carotid Artery
PERIODONTITIS AND VASCULAR DYSFUNCTION
The investigators wish to assess whether intensive periodontal therapy will reduce the burden of chronic periodontal disease and will cause regression or prevent progression of atherosclerosis assessed by a surrogate end-point…
- Trial name
- NCT03072342
- Testing
- Intensive Periodontal Treatment, Control Periodontal Treatment
- Where
- United Kingdom
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University College, London
Carotid Atherosclerosis
Shear Wave Elastography for Carotid Atherosclerotic Plaques
The goal of this prospective diagnostic accuracy cohort study is to compare the accuracy of carotid atherosclerotic plaques stiffness assessed by shear wave elastography (SWE) with greyscale median values (GSM), magnetic…
- Trial name
- NCT06214429
- Testing
- Vascular Ultrasound, Shear Wave Elastography, Greyscale Median
- Where
- Brazil
- Volunteers
- 43 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Ischaemic Stroke, Carotid Endarterectomy
Carotid Endarterectomy Versus Stenting in Patients With Acute Stage of Ischemic Stroke.
The objective of this clinical trial is to compare immediate and long-term results of carotid endarterectomy and carotid stenting in acute period of ischemic stroke.
- Conditions
- Ischaemic Stroke, Carotid Endarterectomy, Carotid Stenting
- Trial name
- NCT07083986
- Testing
- Carotid Artery Stent Placement, carotid endarterectomy
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Pirogov Russian National Research Medical University
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