Clinical trials: Carotid Atherosclerosis
Carotid Stenosis, Carotid Artery Diseases
Early Warning and Optimization Strategy in Carotid Endarterectomy
Carotid endarterectomy has been proven effective in prevention of cerebral vascular events in patients with severe carotid artery stenosis (symptomatic,>50%;asymptomatic,60%).
- Conditions
- Carotid Stenosis, Carotid Artery Diseases, Stroke, Vascular Diseases
- Trial name
- NCT01210937
- Testing
- CEA and TCD monitoring
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking Union Medical College Hospital
Atherosclerosis
Influenza A VIRus and Destabilization of Atherosclerotic Carotid Plaques
Atherosclerosis is the main cause of cardiovascular diseases and is characterized by the accumulation of lipids and inflammatory cells such as macrophages and lymphocytes within the vessel wall of large and medium-sized arteries…
- Trial name
- VIRAL (NCT06217471)
- Testing
- Carotid Endoarterectomy
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- IRCCS Policlinico S. Donato
PsA (Psoriatic Arthritis)
Effect of Metformin on Carotid Atherosclerosis for Non-diabetic Patients With PsA (CAMPA Study)
Background: Psoriatic arthritis (PsA) is a common chronic inflammatory disease with a prevalence up to 670 every 100,000 subjects.
- Trial name
- NCT05988684
- Testing
- Metformin
- Where
- Hong Kong
- Volunteers
- 24 people
- Sponsor
- Chinese University of Hong Kong
Carotid Stenosis, Carotid Atherosclerosis
Comparison Between Different Techniques for Carotid Artery Endarterectomy
the goal of this interventional study is to compare between the conventional and the Eversion techniques in performing carotid endarterectomy in patients with carotid artery stenosis the main question it aim to answer is which…
- Conditions
- Carotid Stenosis, Carotid Atherosclerosis, Carotid Artery Plaque
- Trial name
- NCT06207643
- Testing
- carotid endarterectomy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Coronary Artery Disease, Diabetes Mellitus, Type 2
Exercise Training in Patients With Coronary Heart Disease and Type 2 Diabetes
Diabetes mellitus (DM) is an important risk factor in the development of cardiovascular disease, and people with type 2 diabetes have a two- to four-fold increased risk for cardiovascular morbidity and mortality.
- Conditions
- Coronary Artery Disease, Diabetes Mellitus, Type 2, Atherosclerosis
- Trial name
- EXCADI (NCT01232608)
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 137 people
- Sponsor
- Oslo University Hospital
Carotid Atherosclerosis
Merck Carotid Atherosclerosis Trial (MK-0000-111)(COMPLETED)
This study will examine the effect of statin and niacin therapy on carotid plaque biomarkers
- Trial name
- MCAT (NCT00804843)
- Testing
- Atorvastatin/niacin extended-release, Atorvastatin, Simvastatin
- Volunteers
- 100 people
- Sponsor
- Merck Sharp & Dohme LLC
Vascular Aging
SNRK & Vascular Endothelial Aging
Cardiovascular diseases pose a serious threat to public health, and their prevalence is on the rise year by year. Vascular aging is an independent risk factor for cardiovascular diseases, and endothelial cell senescence is an…
- Trial name
- NCT07591337
- Testing
- serum tests and carotid ultrasound test
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University
Carotid Atherosclerosis
Artificial Intelligence Based Comprehensive Assessment System of Carotid Plaque Stability
Stroke is a common clinical disease with high disability and mortality, which seriously threatens human life and health.Carotid atherosclerotic plaque rupture is an important pathogenic basis of ischemic stroke, so judging the…
- Trial name
- NCT04544657
- Testing
- no intervention
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Atherosclerosis Cardiovascular Disease, Atherosclerosis of Artery
Oral Microbiome in Carotid Atherosclerosis
The goal of this observational study, called OMICA (Oral Microbiome in Carotid Atherosclerosis), is to learn how bacteria living in the mouth may influence the development and stability of plaques in the carotid arteries, which…
- Conditions
- Atherosclerosis Cardiovascular Disease, Atherosclerosis of Artery, Carotid Artery Plaque, Periodontitis
- Trial name
- OMICA (NCT07296965)
- Testing
- Sample Collection
- Where
- Hungary
- Volunteers
- 200 people
- Sponsor
- Semmelweis University Heart and Vascular Center
Hyperlipidemia, Carotid Atherosclerosis
Study on Hyperlipidemia Combined With Carotid Atherosclerosis With ShenJu Granules
This study focuses on PWV as the main outcome, aiming to evaluate the efficacy and safety of ShenJu in treating patients with hyperlipidemia combined with carotid atherosclerosis, and provide a basis for traditional Chinese…
- Trial name
- NCT06166121
- Testing
- ShenJu
- Where
- 2 sites in China
- Volunteers
- 80 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Hypertension, Target Organ Damage
GlycOxiTOD: Multimodal Vascular and Target-Organ Damage Registry
The goal of the GlycOxiTOD observational registry is to improve the early detection and characterization of vascular and other target-organ damage in adults at increased cardiovascular risk.
- Conditions
- Hypertension, Target Organ Damage, Heart Disease Risk Factors, Vascular Stiffness
- Trial name
- GlycOxiTOD (NCT06325800)
- Testing
- Multimodal Cardiovascular Phenotyping
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Complejo Hospitalario Universitario de Santiago
Peripheral Arterial Disease, Peripheral Vascular Diseases
ACHIEVE GRX Registry
This study will evaluate real-world performance of the CorPath GRX System in peripheral vascular interventions.
- Conditions
- Peripheral Arterial Disease, Peripheral Vascular Diseases, Renal Artery Disease, Carotid Artery Diseases
- Trial name
- NCT04513613
- Testing
- Procedure/Surgery: Robotic-PVI
- Sponsor
- Siemens Healthineers Endovascular Robotics, Inc.
Extracranial Atherosclerosis
Images in Extracranial Artery Stenosis
The goals of this trial are: 1. To compare the sensitivity and specificity of various tools including Doppler and magnetic resonance imaging (MRI) for diagnosing vertebral artery stenosis and carotid artery stenosis.
- Trial name
- NCT00173927
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Atherosclerosis
RNA Cloning and Visualization in Human Atherosclerosis
The research objectives of this project are as follows: 1. Obtain high-quality human atherosclerotic arterial samples from diseased donors. 2.
- Trial name
- NCT01928095
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Virginia
Hyperlipidemia, Carotid Artery Diseases
Pitavastatin on Carotid Intima-media Thickness
This study is aimed to analyze the effects of aggressive and conventional lipid lowering therapy with Pravastatin on carotid intima-media thickness (IMT) in patients with hyperlipidemia and abnormal thickening of IMT.
- Trial name
- PEACE (NCT00711919)
- Testing
- Pitavastatin
- Where
- 18 sites in Japan
- Volunteers
- 300 people
- Sponsor
- Kyoto Prefectural University of Medicine
Aging, Aortic Aneurysm, Abdominal
The Intersectional Viborg Screening Program: Cost-(Effectiveness) of Screening for Diabetes and Cardiovascular Diseases
This is an intersectional and interdisciplinary screening program in Viborg Municipality, including 67 years old citizens. This observational study will estimate the cost-effectiveness of a combined screening program for the…
- Conditions
- Aging, Aortic Aneurysm, Abdominal, Hypertension, Mass Screening
- Trial name
- VISP (NCT03395509)
- Where
- Denmark
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Central Jutland Regional Hospital
Established Carotid Atherosclerosis
Carotid Atherosclerosis Regression at Magnetic Resonance Assessment.
The primary objective of this randomized, double blind, placebo controlled pilot study is to determine if therapies aimed at lowering LDL cholesterol (HMGCoA reductase inhibitor - simvastatin) or increasing HDL cholesterol…
- Trial name
- NCT00307307
- Testing
- Niacin/simvastatin compared to simvastatin alone at 2 doses
- Volunteers
- 69 people
- Sponsor
- University of Pennsylvania
Carotid Stenosis, Ischemic Stroke
Comprehensive Assessment of Atherosclerotic Ischemic Stroke Risk and Development of a Prediction Model
This observational study was designed for the assessment of plaque vulnerability in patients with carotid atherosclerotic stenosis and the development of predictive models for the occurrence and recurrence of atherosclerotic…
- Trial name
- CAIS-pre (NCT06315153)
- Where
- 2 sites in China
- Volunteers
- 500 people
- Sponsor
- Xuanwu Hospital, Beijing
Atherosclerosis, Chronic Kidney Disease
Vitamin D Supplementation in CKD - Vascular Function, Structure and Immune Regulation
A pilot study to assess feasibility of methods of an observer-blinded randomised controlled trial of the effect of vitamin D supplementation in Chronic Kidney Disease and low vitamin D levels on markers of vascular function (Flow…
- Trial name
- NCT04380467
- Testing
- Vitamin D (cholecalciferol)
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- St George's, University of London
Atherosclerosis
Study Effect of VIA-2291 on Atherosclerotic Vascular Inflammation in Patients Undergoing Elective Carotid Endarterectomy
This is a study to compare the effect of VIA-2291 vs. Placebo on various inflammatory biomarkers in patients with carotid stenosis scheduled for elective carotid endarterectomy
- Trial name
- NCT00352417
- Testing
- VIA-2291
- Where
- 3 sites in Italy
- Volunteers
- 50 people
- Sponsor
- Tallikut Pharmaceuticals, Inc.