Clinical trials: Carotid Disease
Carotid Atherosclerosis, Seeing Sounds as Colors
Advanced Analysis of the Carotid Phonoangiography and Diseases
Purpose: To investigate the different sound spectrum of carotid arteries and to analyze its relationship to the vessel disease, and to build a new biomarker about vascular disorder.
- Conditions
- Carotid Atherosclerosis, Seeing Sounds as Colors, Stenosis, Stroke
- Trial name
- NCT02049463
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Diabetes Mellitus
Blood Pressure and Subclinical Organ Damage
Background: The purpose of this study is to analyze the relationship between central and peripheral blood pressure (clinic and ambulatory) with vascular structure and function, assessed by carotid intima-media thickness (IMT)…
- Trial name
- Vasorisk (NCT01325064)
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Moyamoya Disease, Moyamoya Syndrome
Chinese Herbal Therapy (Qiqi Shengmai Formula) for Moyamoya Vasculopathy: The CHIMES Trial
Patients diagnosed with moyamoya vasculopathy by imaging and classified as having the Traditional Chinese Medicine (TCM) syndrome of liver-yang hyperactivity will be enrolled.
- Trial name
- NCT07286110
- Testing
- Traditional Chinese Medicine (TCM) Treatment, Conventional medical treatment
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Fudan University
Epistaxis, Atherosclerosis
Carotid Intima Media Thickness (CIMT) in Epistaxis
Epistaxis is a very frequent emergency among adults and often needs specialised treatment in an ENT-department. Among others, atherosclerosis is often named as a reason for an increased risk for Epistaxis.
- Trial name
- NCT03092973
- Testing
- Ultrasound
- Where
- Switzerland
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Carotid Artery Stenosis, Cerebral Small Vessel Diseases
Revascularization Effect on CSVD Burden in Carotid Artery Stenosis
RECAS is a prospective cohort of 1,000 patients with carotid artery stenosis (CAS) and undergoing revascularization therapy or standard medication treatment alone.
- Trial name
- RECAS (NCT06031610)
- Testing
- carotid artery stenting, drug therapy
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Zhejiang Provincial People's Hospital
Carotid Artery Diseases, Aortic Diseases
Intervascular Post-Market Clinical Follow-Up (PMCF) Registry
The purpose of this registry is to evaluate the long-term safety and performance of Intervascular Vascular Grafts and Patches (Intergard Standard, Hemashield, Intergard Silver, Intergard Synergy) for bypass, repair or replacement…
- Conditions
- Carotid Artery Diseases, Aortic Diseases, Peripheral Arterial Diseases
- Trial name
- NCT07322913
- Testing
- Intergard Standard - Collagen Coated Vascular Grafts and Patches, Hemashield - Collagen Coated Vascular Grafts and Patches, Intergard Silver - Antimicrobial Collagen Coated Vascular Grafts and Patches
- Where
- 5 sites in United States, Belgium and 2 more
- Volunteers
- 1,200 people
- Sponsor
- Intervascular
Moyamoya Disease, Gut Microbiota
Gut Microbiota in Patients With Moyamoya Disease
This study is to find out the association between gut microbiota and moyamoya disease.
- Trial name
- NCT04890782
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Cardiogenic Shock, Volume Responsiveness
Volume Responsiveness By Ultrasound Of Carotid Blood Flow In Patients With Cardiogenic Shock
Resuscitation of critically ill patients has changed since the advent of goal directed therapy. Today, practitioners providing fluid resuscitation are attentive of the danger associated with volume depletion while being aware of…
- Conditions
- Cardiogenic Shock, Volume Responsiveness, Ultrasound
- Trial name
- NCT05271227
- Testing
- Transthoracic echocardiography and Carotid artery doppler (PHILIPS HD11 XE ultrasound device) before and after PLR test.
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Atherosclerosis
Office Practice Assessment of Carotid Atherosclerosis Using Handheld Ultrasound (OPACA) Study
The purposes of this study are to determine: 1. Inter-site variability in CIMT image measurement using SonoCalcTM. 2. If non-sonographer health care professionals working in an office practice setting can be trained to follow a…
- Trial name
- NCT00258973
- Testing
- Carotid Ultrasound performed in office practice
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Hypotension, Sepsis
Carotid Doppler Ultrasound for the Measurement of Intravascular Volume Status
Ultrasound represents an attractive non-invasive method to assess hemodynamic status. Understanding dynamic changes in hemodynamics in situations such as hypovolemia, sepsis, and cardiogenic shock can potentially help improve…
- Trial name
- NCT02907931
- Testing
- Point of Care Ultrasound
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Yale University
Intermittent Claudication
Effect of NCX4016 on Walking Distance in Patients With Peripheral Arterial Occlusive Disease (PAOD)
Peripheral arterial disease (PAD) is almost invariably associated with a generalized atherosclerotic involvement of the arterial tree and endothelial dysfunction.
- Trial name
- NCT01256775
- Testing
- NCX-4016
- Where
- Italy
- Volunteers
- 442 people
- Sponsor
- NicOx Research Institute S.r.l.
Carotid Artery Stenosis
Troponin In Carotid Revascularization
Patients undergoing carotid revascularization procedures are at increased risk for the development of short- and long-term cardiac complications.
- Trial name
- TROPICAR (NCT05293067)
- Testing
- high-sensitive troponin
- Where
- Serbia
- Volunteers
- 527 people
- Sponsor
- University of Belgrade
Atherosclerotic Disease, Carotid
Post-Approval Study of the Guidant Carotid Stent Systems and Embolic Protection Systems: CAPTURE
This purpose of this study is to collect data on the FDA-approved ACCULINK(TM) Carotid Stent System and FDA 510(k)-cleared ACCUNET(TM) Embolic Protection System for the treatment of patients with atherosclerotic disease, when…
- Trial name
- NCT00180492
- Testing
- RX ACCULINK(TM) Carotid Stent System and RX ACCUNET(TM) Embolic Protection System
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Abbott Medical Devices
Carotid Artery Occlusion, Middle Cerebral Artery Occlusion
The Carotid and Middle Cerebral Artery Occlusion Surgery Study
The recently published Carotid Occlusion Surgery Study (COSS) failed to show a benefit of extracranial-intracranial (EC-IC) bypass surgery over medical therapy in patients with symptomatic hemodynamically significant carotid…
- Conditions
- Carotid Artery Occlusion, Middle Cerebral Artery Occlusion, Stroke
- Trial name
- CMOSS (NCT01758614)
- Testing
- bypass surgery, Aspirin, Clopidogrel
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Xuanwu Hospital, Beijing
Atheroscleroses, Cerebral, Carotid Plaque
Carotid Plaque-Burden Scale and Outcomes. A Real Life Study
Carotid ultrasonography has been proposed as a tool for prediction of future cardiovascular disease (CVD). Nevertheless, its role in clinical practice remains controversial.
- Trial name
- NCT06187532
- Volunteers
- 1,004 people
- Sponsor
- Fundación para la Formación e Investigación de los Profesionales de la Salud de Extremadura
Atherosclerosis
Natural History of Atherosclerosis
20 patients will be recruited. The aim of the study is to determine the natural progression of atherosclerotic disease.
- Trial name
- NCT00918541
- Where
- 3 sites in Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Carotid Atherosclerosis, Stroke
Diagnosis and Therapy of Vulnerable Atherosclerotic Plaque
The aim of the present study is to examine the atherosclerotic plaque stability using in vivo and in vitro techniques and to investigate the influence of exercise, anti-diabetic, lipid-lowering and cannabinoids receptor…
- Conditions
- Carotid Atherosclerosis, Stroke, Type 2 Diabetes, Metabolic Syndrome
- Trial name
- NCT00636766
- Testing
- atorvastatin, rimonabant, rosiglitazone
- Where
- Greece
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Peripheral Arterial Disease, Peripheral Vascular Diseases
ACHIEVE GRX Registry
This study will evaluate real-world performance of the CorPath GRX System in peripheral vascular interventions.
- Conditions
- Peripheral Arterial Disease, Peripheral Vascular Diseases, Renal Artery Disease, Carotid Artery Diseases
- Trial name
- NCT04513613
- Testing
- Procedure/Surgery: Robotic-PVI
- Sponsor
- Siemens Healthineers Endovascular Robotics, Inc.
Diabetes Mellitus, Type 2, Atherosclerosis of Artery
Molecular Mechanisms and Carotid Atherosclerosis
The role of methylase system and Proprotein convertase subtilisin/kexin type 9 (PCSK9) in the accelerated atherosclerotic progression of diabetic patients is unclear.
- Conditions
- Diabetes Mellitus, Type 2, Atherosclerosis of Artery, Atherosclerotic Plaque
- Trial name
- NCT03962686
- Testing
- statin Oral Tablet plus PCSK9i
- Where
- Italy
- Volunteers
- 76 people
- Sponsor
- University of Campania Luigi Vanvitelli
Prostate Cancer
Internal Carotid Artery Blood Flow in Robot-Assisted Laparoscopic Prostatectomy
The purpose of this study is to evaluate the change of the internal carotid artery blood flow according to the steep trendelenburg position and pneumoperitoneum in patients undergoing robot-assisted laparoscopic prostatectomy.
- Trial name
- NCT04615494
- Testing
- Position
- Where
- South Korea
- Volunteers
- 28 people
- Sponsor
- Asan Medical Center
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